Ursodeoxycholic acid attenuates colonic epithelial secretory function

Journal of Physiology

Volumn 591, Issue 9, 2013, Pages 2307-2318

  Kelly, Orlaith B ^a   Mroz, Magdalena S ^a   Ward, Joseph B J ^a   Colliva, Carolina ^c   Scharl, Michael ^d   Pellicciari, Roberto ^c   Gilmer, John F ^e   Fallon, Padraic G ^f   Hofmann, Alan F ^d   Roda, Aldo ^c   Murray, Frank E ^b   Keely, Stephen J ^a  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b BEAUMONT HOSPITAL   (Ireland)

^c UNIVERSITY OF BOLOGNA   (Italy)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e TRINITY COLLEGE DUBLIN   (Ireland)

^f TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

6ALPHA METHYL URSODEOXYCHOLIC ACID; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CARBACHOL; CARRIER PROTEIN; CHLORIDE ION; FORSKOLIN; LITHOCHOLIC ACID; POTASSIUM CHANNEL; STOMACH SECRETION INHIBITOR; UNCLASSIFIED DRUG; URSODEOXYCHOLIC ACID;

ADULT; AGED; ANIMAL TISSUE; ANTISECRETORY ACTIVITY; ARTICLE; BACTERIAL METABOLISM; BIOTINYLATION; CELL SURFACE; COLON MUCOSA; COLONIC SECRETION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIARRHEA; DRUG ACTIVITY; DRUG MECHANISM; ENZYME INHIBITION; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; VOLTAGE CLAMP;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTIDIARRHEALS; BILE ACIDS AND SALTS; COLON; EPITHELIAL CELLS; HUMANS; MALE; MICE; MICE, INBRED C57BL; MIDDLE AGED; POTASSIUM CHANNEL BLOCKERS; SODIUM-POTASSIUM-EXCHANGING ATPASE; URSODEOXYCHOLIC ACID;

EID: 84877000653     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2013.252544     Document Type: Article

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