메뉴 건너뛰기




Volumn 92, Issue 1, 2009, Pages 79-93

Recent advances in the understanding of bile acid malabsorption

Author keywords

Bile acid malabsorption; Diarrhoea; Mechanisms; SeHCAT

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BILE ACID; BILE ACID SEQUESTRANT; CHOLEST 4 EN 3 ONE; COLESEVELAM; COLESTIPOL; COLESTYRAMINE; DIGOXIN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 19; GLUCOCORTICOID; SELENIUM HOMOCHOLIC ACID TAURINE; TAURINE; THIAZIDE DIURETIC AGENT; THYROID HORMONE; UNCLASSIFIED DRUG;

EID: 72049127573     PISSN: 00071420     EISSN: 14718391     Source Type: Journal    
DOI: 10.1093/bmb/ldp032     Document Type: Review
Times cited : (87)

References (59)
  • 1
    • 0014071178 scopus 로고
    • The syndrome of ileal disease and the broken enterohepatic circulation: Cholerhetic enteropathy
    • Hofmann AF (1967) The syndrome of ileal disease and the broken enterohepatic circulation: cholerhetic enteropathy. Gastroenterology, 52, 752-757.
    • (1967) Gastroenterology , vol.52 , pp. 752-757
    • Hofmann, A.F.1
  • 3
    • 0015767212 scopus 로고
    • Diarrhoea associated with idiopathic bile acid malabsorp-tion Fact or fantasy?
    • Thaysen EH, Pedersen L (1973) Diarrhoea associated with idiopathic bile acid malabsorp-tion. Fact or fantasy? Dan Med Bull, 20, 174-177.
    • (1973) Dan Med Bull , vol.20 , pp. 174-177
    • Thaysen, E.H.1    Pedersen, L.2
  • 5
    • 0025824484 scopus 로고
    • Idiopathic bile acid malabsorption-a review of clinical presentation, diagnosis, and response to treatment
    • Williams AJK, Merrick MV, Eastwood MA (1991) Idiopathic bile acid malabsorption-a review of clinical presentation, diagnosis, and response to treatment. Gut, 32, 1004-1006.
    • (1991) Gut , vol.32 , pp. 1004-1006
    • Williams, A.J.K.1    Merrick, M.V.2    Eastwood, M.A.3
  • 7
    • 69949136438 scopus 로고    scopus 로고
    • Systematic review: The prevalence of idiopathic bile acid malabsorption as diagnosed by SeHCAT scanning in patients with diarrhoea-predominant irritable bowel syndrome
    • Wedlake L, A'Hern R, Russell D, Thomas K, Walters JR, Andreyev HJ (2009) Systematic review: the prevalence of idiopathic bile acid malabsorption as diagnosed by SeHCAT scanning in patients with diarrhoea-predominant irritable bowel syndrome. Alimen Pharm Therap, 30, 707-717.
    • (2009) Alimen Pharm Therap , vol.30 , pp. 707-717
    • Wedlake, L.1    A'Hern, R.2    Russell, D.3    Thomas, K.4    Walters, J.R.5    Andreyev, H.J.6
  • 8
    • 0029920858 scopus 로고    scopus 로고
    • Carrier-mediated jejunal absorption of conjugated bile acids in the guinea pig
    • Amelsberg A, Schteingart CD, Ton-Nu HT, Hofmann AF (1996) Carrier-mediated jejunal absorption of conjugated bile acids in the guinea pig. Gastroenterology, 110, 1098-1106.
    • (1996) Gastroenterology , vol.110 , pp. 1098-1106
    • Amelsberg, A.1    Schteingart, C.D.2    Ton-Nu, H.T.3    Hofmann, A.F.4
  • 9
    • 33751115468 scopus 로고    scopus 로고
    • Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man
    • Lundasen T, Galman C, Angelin B, Rudling M (2006) Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man. J Intern Med, 260, 530-536.
    • (2006) J Intern Med , vol.260 , pp. 530-536
    • Lundasen, T.1    Galman, C.2    Angelin, B.3    Rudling, M.4
  • 10
    • 0037790917 scopus 로고    scopus 로고
    • The enzymes, regulation, and genetics of bile acid synthesis
    • Russell DW (2003) The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem, 72, 137-174.
    • (2003) Annu Rev Biochem , vol.72 , pp. 137-174
    • Russell, D.W.1
  • 11
    • 0028039878 scopus 로고
    • Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter
    • Wong MH, Oelkers P, Craddock AL, Dawson PA (1994) Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter. J Biol Chem, 269, 1340-1347.
    • (1994) J Biol Chem , vol.269 , pp. 1340-1347
    • Wong, M.H.1    Oelkers, P.2    Craddock, A.L.3    Dawson, P.A.4
  • 12
    • 0028800562 scopus 로고
    • Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter
    • Shneider BL, Dawson PA, Christie DM et al. (1995) Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter. J Clin Invest, 95, 745-754.
    • (1995) J Clin Invest , vol.95 , pp. 745-754
    • Shneider, B.L.1    Dawson, P.A.2    Christie, D.M.3
  • 13
    • 0036998185 scopus 로고    scopus 로고
    • In vitro determination of active bile acid absorption in small biopsy specimens obtained endoscopically or surgically from the human intestine
    • Ung KA, Olofsson G, Fae A et al. (2002) In vitro determination of active bile acid absorption in small biopsy specimens obtained endoscopically or surgically from the human intestine. Eur J Clin Invest, 32, 115-121.
    • (2002) Eur J Clin Invest , vol.32 , pp. 115-121
    • Ung, K.A.1    Olofsson, G.2    Fae, A.3
  • 14
    • 0016272230 scopus 로고
    • Gastric emptying and secretion of bile acids, cholesterol, and pancreatic enzymes during digestion. Duodenal perfusion studies in healthy subjects
    • Brunner H, Northfield TC, Hofmann AF, Go VL, Summerskill WH (1974) Gastric emptying and secretion of bile acids, cholesterol, and pancreatic enzymes during digestion. Duodenal perfusion studies in healthy subjects. Mayo Clin Proc, 49, 851-860.
    • (1974) Mayo Clin Proc , vol.49 , pp. 851-860
    • Brunner, H.1    Northfield, T.C.2    Hofmann, A.F.3    Go, V.L.4    Summerskill, W.H.5
  • 15
    • 1242269851 scopus 로고    scopus 로고
    • Regulation of bile acid synthesis: Pathways, nuclear receptors, and mechanisms
    • Chiang JY (2004) Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms. J Hepatol, 40, 539-551.
    • (2004) J Hepatol , vol.40 , pp. 539-551
    • Chiang, J.Y.1
  • 16
    • 0142074212 scopus 로고    scopus 로고
    • Monitoring hepatic cholesterol 7alpha-hydroxylase activity by assay of the stable bile acid intermediate 7alpha-hydroxy-4-cholesten-3-one in peripheral blood
    • Galman C, Arvidsson I, Angelin B, Rudling M (2003) Monitoring hepatic cholesterol 7alpha-hydroxylase activity by assay of the stable bile acid intermediate 7alpha-hydroxy-4-cholesten-3-one in peripheral blood. J Lipid Res, 44, 859-866.
    • (2003) J Lipid Res , vol.44 , pp. 859-866
    • Galman, C.1    Arvidsson, I.2    Angelin, B.3    Rudling, M.4
  • 17
    • 33947134611 scopus 로고    scopus 로고
    • Bile formation and the enterohepatic circulation
    • Johnson L (ed.) 4th ed. Elsevier
    • Dawson P, Benjamin S, Hofmann A (2006) Bile formation and the enterohepatic circulation. In Johnson L (ed.) Physiology of the Gastrointestinal Tract, 4th ed. Elsevier, 1437-1462.
    • (2006) Physiology of the Gastrointestinal Tract , pp. 1437-1462
    • Dawson, P.1    Benjamin, S.2    Hofmann, A.3
  • 18
    • 0027439285 scopus 로고
    • Movement of fatty acids, fatty acid analogues, and bile acids across phospholipid bilayers
    • Kamp F, Hamilton JA, Kamp F, Westerhoff HV, Hamilton JA (1993) Movement of fatty acids, fatty acid analogues, and bile acids across phospholipid bilayers. Biochemistry, 32, 11074-11086.
    • (1993) Biochemistry , vol.32 , pp. 11074-11086
    • Kamp, F.1    Hamilton, J.A.2    Kamp, F.3    Westerhoff, H.V.4    Hamilton, J.A.5
  • 19
    • 0033637121 scopus 로고    scopus 로고
    • A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
    • Goodwin B, Jones SA, Price RR et al. (2000) A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Mol Cell, 6, 517-526.
    • (2000) Mol Cell , vol.6 , pp. 517-526
    • Goodwin, B.1    Jones, S.A.2    Price, R.R.3
  • 20
    • 27844546989 scopus 로고    scopus 로고
    • Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
    • Inagaki T, Choi M, Moschetta A et al. (2005) Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab, 2, 217-225.
    • (2005) Cell Metab , vol.2 , pp. 217-225
    • Inagaki, T.1    Choi, M.2    Moschetta, A.3
  • 21
    • 58949097425 scopus 로고    scopus 로고
    • Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression
    • Song Kh, Li T, Owsley E, Strom S, Chiang JY (2009) Bile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expression. Hepatology, 49, 297-305.
    • (2009) Hepatology , vol.49 , pp. 297-305
    • Kh, S.1    Li, T.2    Owsley, E.3    Strom, S.4    Chiang, J.Y.5
  • 22
    • 65449177586 scopus 로고    scopus 로고
    • High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis
    • Schaap FG, van der Gaag NA, Gouma DJ, Jansen PL (2009) High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis. Hepatology, 49, 1228-1235.
    • (2009) Hepatology , vol.49 , pp. 1228-1235
    • Schaap, F.G.1    Van Der Gaag, N.A.2    Gouma, D.J.3    Jansen, P.L.4
  • 23
    • 27744516236 scopus 로고    scopus 로고
    • Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesis
    • Galman C, Angelin B, Rudling M (2005) Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesis. Gastroenterology, 129, 1445-1453.
    • (2005) Gastroenterology , vol.129 , pp. 1445-1453
    • Galman, C.1    Angelin, B.2    Rudling, M.3
  • 24
    • 0015105518 scopus 로고
    • Colonic secretion of water and electrolytes induced by bile acids: Perfusion studies in man
    • Mekhjian HS, Phillips SF, Hofmann AF (1971) Colonic secretion of water and electrolytes induced by bile acids: perfusion studies in man. J Clin Invest, 50, 1569-1577.
    • (1971) J Clin Invest , vol.50 , pp. 1569-1577
    • Mekhjian, H.S.1    Phillips, S.F.2    Hofmann, A.F.3
  • 25
    • 0019523826 scopus 로고
    • Factors in the mechanism of diarrhea in bile acid malabsorption: Fecal pH-a key determinant
    • McJunkin B, Fromm H, Sarva RP, Amin P (1981) Factors in the mechanism of diarrhea in bile acid malabsorption: fecal pH-a key determinant. Gastroenterology, 80, 1454-1464.
    • (1981) Gastroenterology , vol.80 , pp. 1454-1464
    • McJunkin, B.1    Fromm, H.2    Sarva, R.P.3    Amin, P.4
  • 26
    • 0042929633 scopus 로고    scopus 로고
    • Bile acid malabsorption in patients with chronic diarrhoea: Clinical value of SeHCAT test
    • Wildt S, Rasmussen SN, Madsen JL, Rumessen JJ (2003) Bile acid malabsorption in patients with chronic diarrhoea: clinical value of SeHCAT test. Scand J Gastroenterol, 38, 826-830.
    • (2003) Scand J Gastroenterol , vol.38 , pp. 826-830
    • Wildt, S.1    Rasmussen, S.N.2    Madsen, J.L.3    Rumessen, J.J.4
  • 27
    • 0027977042 scopus 로고
    • Bile acid malabsorption in Crohn's disease and indications for its assessment using SeHCAT
    • Nyhlin H, Merrick MV, Eastwood MA (1994) Bile acid malabsorption in Crohn's disease and indications for its assessment using SeHCAT. Gut, 35, 90-93.
    • (1994) Gut , vol.35 , pp. 90-93
    • Nyhlin, H.1    Merrick, M.V.2    Eastwood, M.A.3
  • 28
    • 0021920402 scopus 로고
    • Is bile acid malabsorption underdiagnosed? An evaluation of accuracy of diagnosis by measurement of SeHCAT retention
    • Merrick MV, Eastwood MA, Ford MJ (1985) Is bile acid malabsorption underdiagnosed? An evaluation of accuracy of diagnosis by measurement of SeHCAT retention. Br Med J (Clin Res Ed), 290, 665-668.
    • (1985) Br Med J (Clin Res Ed) , vol.290 , pp. 665-668
    • Merrick, M.V.1    Eastwood, M.A.2    Ford, M.J.3
  • 29
    • 72049128705 scopus 로고    scopus 로고
    • GE Healthcare
    • Amersham, UK: GE Healthcare, (Ref Type: Pamphlet)
    • GE Healthcare (2008) SeHCAT Prescribing Information. Amersham, UK: GE Healthcare, (Ref Type: Pamphlet).
    • (2008) SeHCAT Prescribing Information
  • 30
    • 0029969524 scopus 로고    scopus 로고
    • Serum 7 alpha-hydroxy-4-cholesten-3-one and selenohomocholyltaurine (SeHCAT) whole body retention in the assessment of bile acid induced diarrhoea
    • Brydon WG, Nyhlin H, Eastwood MA, Merrick MV (1996) Serum 7 alpha-hydroxy-4-cholesten-3-one and selenohomocholyltaurine (SeHCAT) whole body retention in the assessment of bile acid induced diarrhoea. Eur J Gastroenterol Hepatol, 8, 117-123.
    • (1996) Eur J Gastroenterol Hepatol , vol.8 , pp. 117-123
    • Brydon, W.G.1    Nyhlin, H.2    Eastwood, M.A.3    Merrick, M.V.4
  • 31
    • 33645106624 scopus 로고    scopus 로고
    • Normal or increased bile acid uptake in isolated mucosa from patients with bile acid malabsorption
    • Bajor A, Kilander A, Fae A et al. (2006) Normal or increased bile acid uptake in isolated mucosa from patients with bile acid malabsorption. Eur J Gastroenterol Hepatol, 18, 397-403.
    • (2006) Eur J Gastroenterol Hepatol , vol.18 , pp. 397-403
    • Bajor, A.1    Kilander, A.2    Fae, A.3
  • 32
    • 0346607187 scopus 로고    scopus 로고
    • Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor
    • Jung D, Fantin AC, Scheurer U, Fried M, Kullak-Ublick GA (2004) Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor. Gut, 53, 78-84.
    • (2004) Gut , vol.53 , pp. 78-84
    • Jung, D.1    Fantin, A.C.2    Scheurer, U.3    Fried, M.4    Kullak-Ublick, G.A.5
  • 33
    • 72049106461 scopus 로고    scopus 로고
    • 57 ed
    • British National Formulary
    • British National Formulary (2009) 57 ed. BMJ Group and RPS Publishing, 68.
    • (2009) BMJ Group and RPS Publishing , vol.68
  • 34
    • 0022540277 scopus 로고
    • Use of 23-selena-25-homocholyltaurine to detect bile acid malabsorption in patients with ileal dysfunction or diarrhea
    • Sciarretta G, Vicini G, Fagioli G et al. (1986) Use of 23-selena-25-homocholyltaurine to detect bile acid malabsorption in patients with ileal dysfunction or diarrhea. Gastroenterology, 91, 1-9.
    • (1986) Gastroenterology , vol.91 , pp. 1-9
    • Sciarretta, G.1    Vicini, G.2    Fagioli, G.3
  • 35
    • 0023228639 scopus 로고
    • 75Se HCAT test in the detection of bile acid malabsorption in functional diarrhoea and its correlation with small bowel transit
    • Sciarretta G, Fagioli G, Furno A et al. (1987) 75Se HCAT test in the detection of bile acid malabsorption in functional diarrhoea and its correlation with small bowel transit. Gut, 28, 970-975.
    • (1987) Gut , vol.28 , pp. 970-975
    • Sciarretta, G.1    Fagioli, G.2    Furno, A.3
  • 37
    • 0026704832 scopus 로고
    • The prevalence of bile acid malabsorption in irritable bowel syndrome and the effect of cholestyramine: An uncontrolled open multicentre study
    • and the Italian 75SeHCAT Multicentre Study Group.
    • Galatola G, and the Italian 75SeHCAT Multicentre Study Group. (1992) The prevalence of bile acid malabsorption in irritable bowel syndrome and the effect of cholestyramine: an uncontrolled open multicentre study. Eur J Gastroenterol Hepatol, 4, 533-537.
    • (1992) Eur J Gastroenterol Hepatol , vol.4 , pp. 533-537
    • Galatola, G.1
  • 38
    • 0027448881 scopus 로고
    • Bile acid malabsorption in patients with chronic diarrhoea
    • Eusufzai S (1993) Bile acid malabsorption in patients with chronic diarrhoea. Scand J Gastroenterol, 28, 865-868.
    • (1993) Scand J Gastroenterol , vol.28 , pp. 865-868
    • Eusufzai, S.1
  • 39
    • 0030237573 scopus 로고    scopus 로고
    • Radiological bile acid absorption test 75SeHCAT in patients with diarrhoea of unknown cause
    • Rudberg U, Nylander B (1996) Radiological bile acid absorption test 75SeHCAT in patients with diarrhoea of unknown cause. Acta Radiol, 37, 672-675.
    • (1996) Acta Radiol , vol.37 , pp. 672-675
    • Rudberg, U.1    Nylander, B.2
  • 40
    • 0031678671 scopus 로고    scopus 로고
    • Idiopathic bile acid malabsorption: Qualitative and quantitative clinical features and response to cholestyramine
    • Sinha L, Liston R, Testa HJ, Moriarty KJ (1998) Idiopathic bile acid malabsorption: qualitative and quantitative clinical features and response to cholestyramine. Aliment Pharmacol Ther, 12, 839-844.
    • (1998) Aliment Pharmacol Ther , vol.12 , pp. 839-844
    • Sinha, L.1    Liston, R.2    Testa, H.J.3    Moriarty, K.J.4
  • 42
    • 0034788750 scopus 로고    scopus 로고
    • Bile acid malabsorption in microscopic colitis and in previously unexplained functional chronic diarrhea
    • Fernandez-Banares F, Esteve M, Salas A et al. (2001) Bile acid malabsorption in microscopic colitis and in previously unexplained functional chronic diarrhea. Dig Dis Sci, 46, 2231-2238.
    • (2001) Dig Dis Sci , vol.46 , pp. 2231-2238
    • Fernandez-Banares, F.1    Esteve, M.2    Salas, A.3
  • 43
    • 35448957983 scopus 로고    scopus 로고
    • Systematic evaluation of the causes of chronic watery diarrhea with functional characteristics
    • Fernandez-Banares F, Esteve M, Salas A et al. (2007) Systematic evaluation of the causes of chronic watery diarrhea with functional characteristics. Am J Gastroenterol, 102, 2520-2528.
    • (2007) Am J Gastroenterol , vol.102 , pp. 2520-2528
    • Fernandez-Banares, F.1    Esteve, M.2    Salas, A.3
  • 44
    • 14544290041 scopus 로고    scopus 로고
    • New treatment for bile salt malabsorption
    • Puleston J, Morgan H, Andreyev J (2005) New treatment for bile salt malabsorption. Gut, 54, 441-442.
    • (2005) Gut , vol.54 , pp. 441-442
    • Puleston, J.1    Morgan, H.2    Andreyev, J.3
  • 45
    • 72049088070 scopus 로고    scopus 로고
    • A 4-year experience with colesevelam hydrochloride: A new treatment for bile acid malabsorption?
    • Wedlake L, Thomas K, Lalji A, Anagnostopoulos C, Andreyev J (2009) A 4-year experience with colesevelam hydrochloride: a new treatment for bile acid malabsorption? Gut, 58, A117.
    • (2009) Gut , vol.58
    • Wedlake, L.1    Thomas, K.2    Lalji, A.3    Anagnostopoulos, C.4    Andreyev, J.5
  • 46
    • 0030944084 scopus 로고    scopus 로고
    • Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)
    • Oelkers P, Kirby LC, Heubi JE, Dawson PA (1997) Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2). J Clin Invest, 99, 1880-1887.
    • (1997) J Clin Invest , vol.99 , pp. 1880-1887
    • Oelkers, P.1    Kirby, L.C.2    Heubi, J.E.3    Dawson, P.A.4
  • 47
    • 2342604426 scopus 로고    scopus 로고
    • Accelerated regional bowel transit and overweight shown in idiopathic bile acid malabsorption
    • Sadik R, Abrahamsson H, Ung K-A, Stotzer P-O (2004) Accelerated regional bowel transit and overweight shown in idiopathic bile acid malabsorption. Am J Gastroenterol, 99, 711-718.
    • (2004) Am J Gastroenterol , vol.99 , pp. 711-718
    • Sadik, R.1    Abrahamsson, H.2    Ung, K.-A.3    Stotzer, P.-O.4
  • 48
    • 70349496807 scopus 로고    scopus 로고
    • A new mechanism for bile acid diarrhea: Defective feedback inhibition of bile acid biosynthesis
    • press. Epub ahead of print 2 November 2009
    • Walters JRF, Tasleem AM, Omer OS et al. (2009) A new mechanism for bile acid diarrhea: defective feedback inhibition of bile acid biosynthesis. Clin Gastro Hepatol. In press. Epub ahead of print 2 November 2009.
    • (2009) Clin Gastro Hepatol
    • Walters, J.R.F.1    Tasleem, A.M.2    Omer, O.S.3
  • 49
    • 0346100571 scopus 로고    scopus 로고
    • Enterohepatic Bile Salt Transporters in Normal Physiology and Liver Disease
    • DOI 10.1053/j.gastro.2003.06.005
    • Kullak-Ublick GA, Stieger B, Meier PJ (2004) Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology, 126, 322-342. (Pubitemid 38040747)
    • (2004) Gastroenterology , vol.126 , Issue.SUPPL. 1 , pp. 322-342
    • Kullak-Ublick, G.A.1    Stieger, B.2    Meier, P.J.3
  • 50
    • 0029075432 scopus 로고
    • Cloning and chromosomal localization of the human ileal lipid-binding protein
    • Oelkers P, Dawson PA (1995) Cloning and chromosomal localization of the human ileal lipid-binding protein. Biochim Biophys Acta, 1257, 199-202.
    • (1995) Biochim Biophys Acta , vol.1257 , pp. 199-202
    • Oelkers, P.1    Dawson, P.A.2
  • 51
    • 14844291348 scopus 로고    scopus 로고
    • The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter
    • Dawson PA, Hubbert M, Haywood J et al. (2005) The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter. J Biol Chem, 280, 6960-6968.
    • (2005) J Biol Chem , vol.280 , pp. 6960-6968
    • Dawson, P.A.1    Hubbert, M.2    Haywood, J.3
  • 53
    • 0034878273 scopus 로고    scopus 로고
    • Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption
    • Montagnani M, Love MW, Rössel P, Dawson PA, Qvist P (2001) Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption. Scand J Gastroenterol, 36, 1077-1080.
    • (2001) Scand J Gastroenterol , vol.36 , pp. 1077-1080
    • Montagnani, M.1    Love, M.W.2    Rössel, P.3    Dawson, P.A.4    Qvist, P.5
  • 54
    • 33846002724 scopus 로고    scopus 로고
    • Analysis of ileal sodium/bile acid cotransporter and related nuclear receptor genes in a family with multiple cases of idiopathic bile acid malabsorption
    • Montagnani M, Abrahamsson A, Galman C et al. (2006) Analysis of ileal sodium/bile acid cotransporter and related nuclear receptor genes in a family with multiple cases of idiopathic bile acid malabsorption. World J Gastroenterol, 12, 7710-7714.
    • (2006) World J Gastroenterol , vol.12 , pp. 7710-7714
    • Montagnani, M.1    Abrahamsson, A.2    Galman, C.3
  • 55
    • 42149145538 scopus 로고    scopus 로고
    • Exploring possible mechanisms for primary bile acid malabsorption: Evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea
    • Balesaria S, Pell RJ, Abbott LJ et al. (2008) Exploring possible mechanisms for primary bile acid malabsorption: evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea. Eur J Gastroenterol Hepatol, 20, 413-422.
    • (2008) Eur J Gastroenterol Hepatol , vol.20 , pp. 413-422
    • Balesaria, S.1    Pell, R.J.2    Abbott, L.J.3
  • 57
    • 0026165709 scopus 로고
    • Primary bile acid diarrhoea without an ileal carrier defect: Quantification of active bile acid transport across the ileal brush border membrane
    • van Tilburg AJ, de Rooij FW, van den Berg JW, van Blankenstein M (1991) Primary bile acid diarrhoea without an ileal carrier defect: quantification of active bile acid transport across the ileal brush border membrane. Gut, 32, 500-503.
    • (1991) Gut , vol.32 , pp. 500-503
    • Van Tilburg, A.J.1    De Rooij, F.W.2    Van Den Berg, J.W.3    Van Blankenstein, M.4
  • 58
    • 0023237863 scopus 로고
    • Primary bile acid malabsorption. Histologic and immunologic study in three patients
    • Popovic OS, Kostic KM, Milovic VB et al. (1987) Primary bile acid malabsorption. Histologic and immunologic study in three patients. Gastroenterology, 92, 1851-1858.
    • (1987) Gastroenterology , vol.92 , pp. 1851-1858
    • Popovic, O.S.1    Kostic, K.M.2    Milovic, V.B.3
  • 59
    • 37249011815 scopus 로고    scopus 로고
    • FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption
    • Jung D, Inagaki T, Gerard RD et al. (2007) FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption. J Lipid Res, 48, 2693-2700.
    • (2007) J Lipid Res , vol.48 , pp. 2693-2700
    • Jung, D.1    Inagaki, T.2    Gerard, R.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.