Lubiprostone activates Cl- secretion via cAMP signaling and increases membrane CFTR in the human colon carcinoma cell line, T84

Digestive Diseases and Sciences

Volumn 56, Issue 2, 2011, Pages 339-351

  Ao, Mei ^a   Venkatasubramanian, Jayashree ^a   Boonkaewwan, Chaiwat ^a,b   Ganesan, Nivetha ^a   Syed, Asma ^a   Benya, Richard V ^a   Rao, Mrinalini C ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b KASETSART UNIVERSITY   (Thailand)

Author keywords

cAMP signaling; Cl secretion; Cystic fibrosis transmembrane conductance regulator; Lubiprostone; T84

Indexed keywords

CHLORIDE ION; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; IODIDE; LUBIPROSTONE; TRANSMEMBRANE CONDUCTANCE REGULATOR;

APICAL MEMBRANE; ARTICLE; BIOTINYLATION; CELL MEMBRANE; CELL STRAIN T84; CHLORIDE TRANSPORT; COLON CARCINOMA; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SHORT CIRCUIT CURRENT; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

ALPROSTADIL; BENZOIC ACIDS; BIOLOGICAL TRANSPORT; BUMETANIDE; CARCINOMA; CATHARTICS; CELL LINE, TUMOR; CELL MEMBRANE; CHLORIDES; COLONIC NEOPLASMS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DOSE-RESPONSE RELATIONSHIP, DRUG; FORSKOLIN; GENE EXPRESSION REGULATION; HUMANS; THIAZOLIDINES;

EID: 79952438594     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-010-1495-8     Document Type: Article

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