Bile acids modulate tight junction structure and barrier function of Caco-2 monolayers via EGFR activation

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 294, Issue 4, 2008, Pages

  Raimondi, Francesco ^a   Santoro, Pasquale ^a   Barone, Maria Vittoria ^a   Pappacoda, Serena ^a   Barretta, Maria Luisa ^a   Nanayakkara, Merlin ^a   Apicella, Carmela ^a   Capasso, Letizia ^a   Paludetto, Roberto ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Epidermal growth factor; Epithelial growth factor receptor; Intestinal permeability

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; BILE ACID; CHENODEOXYCHOLIC ACID; CHOLIC ACID; DEOXYCHOLIC ACID; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUSCARINIC RECEPTOR; OCCLUDIN; URSODEOXYCHOLIC ACID;

ARTICLE; CELL STRAIN CACO 2; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DEPHOSPHORYLATION; ELECTRIC RESISTANCE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INTESTINE MUCOSA PERMEABILITY; NECROTIZING ENTEROCOLITIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STATISTICAL ANALYSIS; TIGHT JUNCTION;

ANTIBODIES, MONOCLONAL; BILE ACIDS AND SALTS; CACO-2 CELLS; CHENODEOXYCHOLIC ACID; CHOLIC ACID; DEOXYCHOLIC ACID; DEXTRANS; ELECTRIC IMPEDANCE; ENZYME ACTIVATION; EPIDERMAL GROWTH FACTOR; HUMANS; INTESTINAL MUCOSA; KINETICS; MEMBRANE PROTEINS; ORGANOMETALLIC COMPOUNDS; ORGANOPHOSPHORUS COMPOUNDS; PERMEABILITY; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PYRIMIDINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; SRC-FAMILY KINASES; TIGHT JUNCTIONS;

EID: 42049106193     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00043.2007     Document Type: Article

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