Lithocholic acid attenuates cAMP-dependent Cl– secretion in human colonic epithelial T84 cells

American Journal of Physiology - Cell Physiology

Volumn 310, Issue 11, 2016, Pages C1010-C1023

  Ao, Mei ^a   Domingue, Jada C ^a   Khan, Nabihah ^b   Javed, Fatima ^b   Osmani, Kashif ^a   Sarathy, Jayashree ^a,b   Rao, Mrinalini C ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b BENEDICTINE UNIVERSITY   (United States)

Author keywords

Adenosine 3 ,5 cyclic monophosphate signaling; Cystic fibrosis transmembrane conductance regulator; Potassium ion conductances

Indexed keywords

BILE ACID SPECIFIC TRANSMEMBRANE PROTEIN COUPLED RECEPTOR 5; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHLORIDE ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FARNESOID X RECEPTOR; LITHOCHOLIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MUSCARINIC M3 RECEPTOR; PROTEIN; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR; ANTIDIARRHEAL AGENT; CFTR PROTEIN, HUMAN; CHLORIDE; CYCLIC AMP; MAPK1 PROTEIN, HUMAN; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT;

APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CELL LEVEL; CELL MEMBRANE PERMEABILITY; CELL VIABILITY; CELLULAR SECRETION; CHLORIDE CURRENT; CHOLESTASIS; COLON CELL; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SYNTHESIS; IC50; INTESTINE EPITHELIUM CELL; INTRACELLULAR SIGNALING; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN INDUCTION; PROTEIN SYNTHESIS INHIBITION; SHORT CIRCUIT CURRENT; TRANSEPITHELIAL RESISTANCE; AGONISTS; CELL LINE; COLON; DOSE RESPONSE; DRUG EFFECTS; EPITHELIUM CELL; HUMAN; INTESTINAL SECRETIONS; INTESTINE MUCOSA; METABOLISM; PHOSPHORYLATION; SECRETION (PROCESS); SIGNAL TRANSDUCTION; TIME FACTOR;

ANTIDIARRHEALS; CELL LINE; CHLORIDES; COLON; CYCLIC AMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; HUMANS; INTESTINAL MUCOSA; INTESTINAL SECRETIONS; LITHOCHOLIC ACID; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHORYLATION; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84983677567     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00350.2015     Document Type: Article

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