Regulation of immune cell signaling by SHIP1: A phosphatase, scaffold protein, and potential therapeutic target

European Journal of Immunology

Volumn 47, Issue 6, 2017, Pages 932-945

  Pauls, Samantha D ^a   Marshall, Aaron J ^a  

^a UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Cellular activation; Homeostasis; Inhibitory receptors; Protein protein interactions; Signal transduction

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATASE; PHOSPHOINOSITIDE PHOSPHATASE; PHOSPHOINOSITIDE PHOSPHATASE SHIP1; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG; INPP5D PROTEIN, HUMAN; INPP5D PROTEIN, MOUSE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 5 PHOSPHATASE; PROTEIN;

AUTOIMMUNITY; B LYMPHOCYTE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CYTOSKELETON; DENDRITIC CELL; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME STRUCTURE; HUMAN; IMMUNOCOMPETENT CELL; IMMUNOREGULATION; INFLAMMATORY DISEASE; LEUKEMIA; LYMPHOMA; MACROPHAGE; MAST CELL; NATURAL KILLER CELL; PLECKSTRIN HOMOLOGY DOMAIN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; T LYMPHOCYTE; ANIMAL; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HOMEOSTASIS; IMMUNOLOGY; METABOLISM; MOUSE; PHOSPHORYLATION;

ANIMALS; B-LYMPHOCYTES; DENDRITIC CELLS; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMANS; KILLER CELLS, NATURAL; MACROPHAGES; MAST CELLS; MICE; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHATIDYLINOSITOL-3,4,5-TRISPHOSPHATE 5-PHOSPHATASES; PHOSPHORYLATION; PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 85019964470     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201646795     Document Type: Review

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