SHIP-1 couples to the Dectin-1 hemITAM and selectively modulates reactive oxygen species production in dendritic cells in response to Candida albicans

Journal of Immunology

Volumn 195, Issue 9, 2015, Pages 4466-4478

  Blanco Menéndez, Noelia ^a   Del Fresno, Carlos ^a   Fernandes, Sandra ^b   Calvo, Enrique ^a   Conde Garrosa, Ruth ^a   Kerr, William G ^b,c   Sancho, David ^a  

^a CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^b State University of New York Upstate Medical University: College of Medicine   (United States)

^c SYRACUSE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DECTIN 1; GLYCOPROTEIN P 15095; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMITAM PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE SYK; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SHIP 1 PROTEIN; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG; INOSITOL POLYPHOSPHATE 5 PHOSPHATASE; INPP5D PROTEIN, MOUSE; LECTIN; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 5 PHOSPHATASE; PROTEIN BINDING;

ARTICLE; BINDING AFFINITY; BINDING SITE; CANDIDA ALBICANS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; FUNGUS IDENTIFICATION; IMMUNE RESPONSE; MOLECULAR DYNAMICS; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; ANIMAL; BONE MARROW CELL; CONFOCAL MICROSCOPY; DENDRITIC CELL; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; PHAGOSOME; PHYSIOLOGY; PROTEIN MOTIF; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; BONE MARROW CELLS; CANDIDA ALBICANS; DENDRITIC CELLS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HOST-PATHOGEN INTERACTIONS; INOSITOL POLYPHOSPHATE 5-PHOSPHATASES; LECTINS, C-TYPE; MACROPHAGES; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; NF-KAPPA B; NFATC TRANSCRIPTION FACTORS; PHAGOCYTOSIS; PHAGOSOMES; PHOSPHATIDYLINOSITOL-3,4,5-TRISPHOSPHATE 5-PHOSPHATASES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN BINDING; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84945156965     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402874     Document Type: Article

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