Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs

Cell Reports

Volumn 19, Issue 8, 2017, Pages 1614-1630

  Yoshinaga, Masanori ^a,b   Nakatsuka, Yoshinari ^a,b   Vandenbon, Alexis ^c   Ori, Daisuke ^a,f   Uehata, Takuya ^a,b   Tsujimura, Tohru ^d   Suzuki, Yutaka ^e   Mino, Takashi ^a,b   Takeuchi, Osamu ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN AGENCY FOR MEDICAL RESEARCH AND DEVELOPMENT   (Japan)

^c OSAKA UNIVERSITY   (Japan)

^d HYOGO COLLEGE OF MEDICINE   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f NARA INSTITUTE OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

anemia; endonuclease; HIF2 ; iron metabolism; mRNA degradation; transferrin receptor

Indexed keywords

CD71 ANTIGEN; HEPCIDIN; MESSENGER RNA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE DOMAIN CONTAINING PROTEIN 3; REGNASE 1; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; FERRITIN; IRON; LEUKOCYTE ANTIGEN; PHD3 PROTEIN, MOUSE; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; REGNASE-1, MOUSE; RIBONUCLEASE; TRANSFERRIN RECEPTOR;

ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; FEMALE; GENE; GENE FUNCTION; HOMEOSTASIS; IN VIVO STUDY; IRON DEFICIENCY ANEMIA; IRON METABOLISM; IRON TRANSPORT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REGNASE 1 GENE; TFR1 GENE; UPREGULATION; ANEMIA; ANIMAL; DEFICIENCY; DNA RESPONSIVE ELEMENT; DUODENUM; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PATHOLOGY; PROMOTER REGION; RNA STABILITY;

ANEMIA; ANIMALS; ANTIGENS, CD; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; DUODENUM; FERRITINS; HOMEOSTASIS; IRON; MICE; PROCOLLAGEN-PROLINE DIOXYGENASE; PROMOTER REGIONS, GENETIC; RECEPTORS, TRANSFERRIN; RESPONSE ELEMENTS; RIBONUCLEASES; RNA STABILITY; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 85019704408     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.05.009     Document Type: Article

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