-
1
-
-
84940556588
-
An efficient system for intracellular delivery of beta-lactam antibiotics to overcome bacterial resistance
-
Abed, N., Saïd-Hassane, F., Zouhiri, F., Mougin, J., Nicolas, V., Desmaële, D., et al. (2015). An efficient system for intracellular delivery of beta-lactam antibiotics to overcome bacterial resistance. Sci. Rep. 5:13500. doi: 10.1038/srep13500
-
(2015)
Sci. Rep
, vol.5
, pp. 13500
-
-
Abed, N.1
Saïd-Hassane, F.2
Zouhiri, F.3
Mougin, J.4
Nicolas, V.5
Desmaële, D.6
-
2
-
-
33644942482
-
Genetic improvement of processes yielding microbial products
-
Adrio, J. L., and Demain, A. L. (2006). Genetic improvement of processes yielding microbial products. FEMS Microbiol. Rev. 30, 187-214. doi: 10.1111/j.1574-6976.2005.00009.x
-
(2006)
FEMS Microbiol. Rev
, vol.30
, pp. 187-214
-
-
Adrio, J.L.1
Demain, A.L.2
-
3
-
-
24644515752
-
Tuning genetic control through promoter engineering
-
Alper, H., Fischer, C., Nevoigt, E., and Stephanopoulos, G. (2005). Tuning genetic control through promoter engineering. Proc. Natl. Acad. Sci. U.S.A. 102, 12678-12683. doi: 10.1073/pnas.0504604102
-
(2005)
Proc. Natl. Acad. Sci. U.S.A
, vol.102
, pp. 12678-12683
-
-
Alper, H.1
Fischer, C.2
Nevoigt, E.3
Stephanopoulos, G.4
-
4
-
-
84921367701
-
Chemical biology applied to the study of bacterial pathogens
-
Anthouard, R., and DiRita, V. J. (2015). Chemical biology applied to the study of bacterial pathogens. Infect. Immun. 83, 456-469. doi: 10.1128/IAI.02021-14
-
(2015)
Infect. Immun
, vol.83
, pp. 456-469
-
-
Anthouard, R.1
DiRita, V.J.2
-
5
-
-
84927509844
-
Heterologous production of fungal secondary metabolites in Aspergilli
-
Anyaogu, D. C., and Mortensen, U. H. (2015). Heterologous production of fungal secondary metabolites in Aspergilli. Front. Microbiol. 6:77. doi: 10.3389/fmicb.2015.00077
-
(2015)
Front. Microbiol
, vol.6
, pp. 77
-
-
Anyaogu, D.C.1
Mortensen, U.H.2
-
6
-
-
84940055507
-
Discovery and resupply of pharmacologically active plant-derived natural products: a review
-
Atanasov, A. G., Waltenberger, B., Pferschy-Wenzig, E. M., Linder, T., Wawrosch, C., Uhrin, P., et al. (2015). Discovery and resupply of pharmacologically active plant-derived natural products: a review. Biotechnol. Adv. 33, 1582-1614. doi: 10.1016/j.biotechadv.2015.08.001
-
(2015)
Biotechnol. Adv
, vol.33
, pp. 1582-1614
-
-
Atanasov, A.G.1
Waltenberger, B.2
Pferschy-Wenzig, E.M.3
Linder, T.4
Wawrosch, C.5
Uhrin, P.6
-
7
-
-
14544294545
-
Bioactive microbial metabolites
-
Berdy, J. (2005). Bioactive microbial metabolites. J. Antibiot. 58, 1-26. doi: 10.1038/ja.2005.1
-
(2005)
J. Antibiot
, vol.58
, pp. 1-26
-
-
Berdy, J.1
-
8
-
-
84926255529
-
Metabolite induction via microorganism co-culture: a potential way to enhance chemical diversity for drug discovery
-
Bertrand, S., Bohni, N., Schnee, S., Schumpp, O., Gindro, K., and Wolfender, J. L. (2014). Metabolite induction via microorganism co-culture: a potential way to enhance chemical diversity for drug discovery. Biotechnol. Adv. 32, 1180-1204. doi: 10.1016/j.biotechadv.2014.03.001
-
(2014)
Biotechnol. Adv
, vol.32
, pp. 1180-1204
-
-
Bertrand, S.1
Bohni, N.2
Schnee, S.3
Schumpp, O.4
Gindro, K.5
Wolfender, J.L.6
-
9
-
-
84907899428
-
Natural product and natural product derived drugs in clinical trials
-
Butler, M. S., Robertson, A. A., and Cooper, M. A. (2014). Natural product and natural product derived drugs in clinical trials. Nat. Prod. Rep. 31, 1612-1661. doi: 10.1039/C4NP00064A
-
(2014)
Nat. Prod. Rep
, vol.31
, pp. 1612-1661
-
-
Butler, M.S.1
Robertson, A.A.2
Cooper, M.A.3
-
10
-
-
57649100762
-
Metabolic engineering for plant natural product biosynthesis in microbes
-
Chemler, J. A., and Koffas, M. A. (2008). Metabolic engineering for plant natural product biosynthesis in microbes. Curr. Opin. Biotechnol. 19, 597-605. doi: 10.1016/j.copbio.2008.10.011
-
(2008)
Curr. Opin. Biotechnol
, vol.19
, pp. 597-605
-
-
Chemler, J.A.1
Koffas, M.A.2
-
11
-
-
84863229940
-
DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency
-
Conrado, R. J., Wu, G. C., Boock, J. T., Xu, H., Chen, S. Y., Lebar, T., et al. (2012). DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency. Nucleic Acids Res. 40, 1879-1889. doi: 10.1093/nar/gkr888
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 1879-1889
-
-
Conrado, R.J.1
Wu, G.C.2
Boock, J.T.3
Xu, H.4
Chen, S.Y.5
Lebar, T.6
-
12
-
-
79960697001
-
Organization of intracellular reactions with rationally designed RNA assemblies
-
Delebecque, C. J., Lindner, A. B., Silver, P. A., and Aldaye, F. A. (2011). Organization of intracellular reactions with rationally designed RNA assemblies. Science 333, 470-474. doi: 10.1126/science.1206938
-
(2011)
Science
, vol.333
, pp. 470-474
-
-
Delebecque, C.J.1
Lindner, A.B.2
Silver, P.A.3
Aldaye, F.A.4
-
13
-
-
62449089680
-
Microbial drug discovery: 80 years of progress
-
Demain, A. L., and Sanchez, S. (2009). Microbial drug discovery: 80 years of progress. J. Antibiot. 62, 5-16. doi: 10.1038/ja.2008.16
-
(2009)
J. Antibiot
, vol.62
, pp. 5-16
-
-
Demain, A.L.1
Sanchez, S.2
-
14
-
-
84978087336
-
Enhanced production of nargenicin A1 and creation of a novel derivative using a synthetic biology platform
-
Dhakal, D., Chaudhary, A. K., Yi, J. S., Pokhrel, A. R., Shrestha, B., Parajuli, P., et al. (2016). Enhanced production of nargenicin A1 and creation of a novel derivative using a synthetic biology platform. Appl. Microbiol. Biotechnol. 100, 9917-9931. doi: 10.1007/s00253-016-7705-3
-
(2016)
Appl. Microbiol. Biotechnol
, vol.100
, pp. 9917-9931
-
-
Dhakal, D.1
Chaudhary, A.K.2
Yi, J.S.3
Pokhrel, A.R.4
Shrestha, B.5
Parajuli, P.6
-
15
-
-
84924040451
-
Enhanced production of nargenicin A1 and generation of novel glycosylated derivatives
-
Dhakal, D., Le, T. T., Pandey, R. P., Jha, A. K., Gurung, R., Parajuli, P., et al. (2015). Enhanced production of nargenicin A1 and generation of novel glycosylated derivatives. Appl. Biochem. Biotechnol. 175, 2934-2949. doi: 10.1007/s12010-014-1472-3
-
(2015)
Appl. Biochem. Biotechnol
, vol.175
, pp. 2934-2949
-
-
Dhakal, D.1
Le, T.T.2
Pandey, R.P.3
Jha, A.K.4
Gurung, R.5
Parajuli, P.6
-
16
-
-
84938936179
-
Commentary: toward a new focus in antibiotic and drug discovery from the Streptomyces arsenal
-
Dhakal, D., and Sohng, J. K. (2015). Commentary: toward a new focus in antibiotic and drug discovery from the Streptomyces arsenal. Front. Microbiol. 6:727. doi: 10.3389/fmicb.2015.00727
-
(2015)
Front. Microbiol
, vol.6
, pp. 727
-
-
Dhakal, D.1
Sohng, J.K.2
-
17
-
-
68449088806
-
Synthetic protein scaffolds provide modular control over metabolic flux
-
Dueber, J. E., Wu, G. C., Malmirchegini, G. R., Moon, T. S., Petzold, C. J., Ullal, A. V., et al. (2009). Synthetic protein scaffolds provide modular control over metabolic flux. Nat. Biotechnol. 27, 753-759. doi: 10.1038/nbt.1557
-
(2009)
Nat. Biotechnol
, vol.27
, pp. 753-759
-
-
Dueber, J.E.1
Wu, G.C.2
Malmirchegini, G.R.3
Moon, T.S.4
Petzold, C.J.5
Ullal, A.V.6
-
18
-
-
84941346066
-
Complete biosynthesis of opioids in yeast
-
Galanie, S., Thodey, K., Trenchard, I. J., Interrante, M. F., and Smolke, C. D. (2015). Complete biosynthesis of opioids in yeast. Science 349, 1095-1100. doi: 10.1126/science.aac9373
-
(2015)
Science
, vol.349
, pp. 1095-1100
-
-
Galanie, S.1
Thodey, K.2
Trenchard, I.J.3
Interrante, M.F.4
Smolke, C.D.5
-
19
-
-
84922394953
-
Co-culture systems and technologies: taking synthetic biology to the next level
-
Goers, L., Freemont, P., and Polizzi, K. M. (2014). Co-culture systems and technologies: taking synthetic biology to the next level. J. R. Soc. Interface 11:20140065. doi: 10.1098/rsif.2014.0065
-
(2014)
J. R. Soc. Interface
, vol.11
-
-
Goers, L.1
Freemont, P.2
Polizzi, K.M.3
-
20
-
-
79951846247
-
Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters
-
Gomez-Escribano, J. P., and Bibb, M. J. (2011). Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters. Microb. Biotechnol. 4, 207-215. doi: 10.1111/j.1751-7915.2010.00219.x
-
(2011)
Microb. Biotechnol
, vol.4
, pp. 207-215
-
-
Gomez-Escribano, J.P.1
Bibb, M.J.2
-
21
-
-
84863946395
-
The generation of "unnatural" products: synthetic biology meets synthetic chemistry
-
Goss, R. J., Shankar, S., and Fayad, A. A. (2012). The generation of "unnatural" products: synthetic biology meets synthetic chemistry. Nat. Prod. Rep. 29, 870-889. doi: 10.1039/c2np00001f
-
(2012)
Nat. Prod. Rep
, vol.29
, pp. 870-889
-
-
Goss, R.J.1
Shankar, S.2
Fayad, A.A.3
-
22
-
-
84935468676
-
Enhanced antibacterial and anti-biofilm activities of silver nanoparticles against Gram-negative and Gram-positive bacteria
-
Gurunathan, S., Han, J. W., Kwon, D. N., and Kim, J. H. (2014). Enhanced antibacterial and anti-biofilm activities of silver nanoparticles against Gram-negative and Gram-positive bacteria. Nanoscale Res. Lett. 9:373. doi: 10.1186/1556-276X-9-373
-
(2014)
Nanoscale Res. Lett
, vol.9
, pp. 373
-
-
Gurunathan, S.1
Han, J.W.2
Kwon, D.N.3
Kim, J.H.4
-
23
-
-
84926205808
-
The re-emergence of natural products for drug discovery in the genomics era
-
Harvey, A. L., Edrada-Ebel, R., and Quinn, R. J. (2015). The re-emergence of natural products for drug discovery in the genomics era. Nat. Rev. Drug Discov. 14, 111-129. doi: 10.1038/nrd4510
-
(2015)
Nat. Rev. Drug Discov
, vol.14
, pp. 111-129
-
-
Harvey, A.L.1
Edrada-Ebel, R.2
Quinn, R.J.3
-
24
-
-
84864275239
-
Precursor directed biosynthesis of an orthogonally functional erythromycin analogue: selectivity in the ribosome macrolide binding pocket
-
Harvey, C. J., Puglisi, J. D., Pande, V. S., Cane, D. E., and Khosla, C. (2012). Precursor directed biosynthesis of an orthogonally functional erythromycin analogue: selectivity in the ribosome macrolide binding pocket. J. Am. Chem. Soc. 134, 12259-12265. doi: 10.1021/ja304682q
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 12259-12265
-
-
Harvey, C.J.1
Puglisi, J.D.2
Pande, V.S.3
Cane, D.E.4
Khosla, C.5
-
25
-
-
84885360495
-
Antimicrobial compounds from natural sources
-
Hayashi, M. A., Bizerra, F. C., and Da-Silva, P. I. (2013). Antimicrobial compounds from natural sources. Front. Microbiol. 4:195. doi: 10.3389/fmicb.2013.00195
-
(2013)
Front. Microbiol
, vol.4
, pp. 195
-
-
Hayashi, M.A.1
Bizerra, F.C.2
Da-Silva, P.I.3
-
26
-
-
79958015012
-
Role of natural product diversity in chemical biology
-
Hong, J. (2011). Role of natural product diversity in chemical biology. Curr. Opin. Chem. Biol. 15, 350-354. doi: 10.1016/j.cbpa.2011.03.004
-
(2011)
Curr. Opin. Chem. Biol
, vol.15
, pp. 350-354
-
-
Hong, J.1
-
27
-
-
84940006777
-
Structural modification of herboxidiene by substrate-flexible cytochrome P450 and glycosyltransferase
-
Jha, A. K., Dhakal, D., Van, P. T. T., Pokhrel, A. R., Yamaguchi, T., Jung, H. J., et al. (2015). Structural modification of herboxidiene by substrate-flexible cytochrome P450 and glycosyltransferase. Appl. Microbiol. Biotechnol. 99, 3421-3431. doi: 10.1007/s00253-015-6431-6
-
(2015)
Appl. Microbiol. Biotechnol
, vol.99
, pp. 3421-3431
-
-
Jha, A.K.1
Dhakal, D.2
Van, P.T.T.3
Pokhrel, A.R.4
Yamaguchi, T.5
Jung, H.J.6
-
28
-
-
84859772410
-
Synthetic biology and the development of tools for metabolic engineering
-
Keasling, J. D. (2012). Synthetic biology and the development of tools for metabolic engineering. Metab. Eng. 14, 189-195. doi: 10.1016/j.ymben.2012.01.004
-
(2012)
Metab. Eng
, vol.14
, pp. 189-195
-
-
Keasling, J.D.1
-
29
-
-
38849174356
-
Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products
-
Kennedy, J. (2008). Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products. Nat. Prod. Rep. 25, 25-34. doi: 10.1039/B707678A
-
(2008)
Nat. Prod. Rep
, vol.25
, pp. 25-34
-
-
Kennedy, J.1
-
30
-
-
84939541097
-
Reinvigorating natural product combinatorial biosynthesis with synthetic biology
-
Kim, E., Moore, B. S., and Yoon, Y. J. (2015). Reinvigorating natural product combinatorial biosynthesis with synthetic biology. Nat. Chem. Biol. 11, 649-659. doi: 10.1038/nchembio.1893
-
(2015)
Nat. Chem. Biol
, vol.11
, pp. 649-659
-
-
Kim, E.1
Moore, B.S.2
Yoon, Y.J.3
-
31
-
-
34948842023
-
Total synthesis approaches to natural product derivatives based on the combination of chemical synthesis and metabolic engineering
-
Kirschning, A., Taft, F., and Knobloch, T. (2007). Total synthesis approaches to natural product derivatives based on the combination of chemical synthesis and metabolic engineering. Org. Biomol. Chem. 5, 3245-3259. doi: 10.1039/b709549j
-
(2007)
Org. Biomol. Chem
, vol.5
, pp. 3245-3259
-
-
Kirschning, A.1
Taft, F.2
Knobloch, T.3
-
32
-
-
84979531773
-
Goodbye to brute force in antibiotic discovery?
-
Kolter, R., and van Wezel, G. P. (2016). Goodbye to brute force in antibiotic discovery? Nat. Microbiol. 1:15020. doi: 10.1038/nmicrobiol.2015.20
-
(2016)
Nat. Microbiol
, vol.1
, pp. 15020
-
-
Kolter, R.1
van Wezel, G.P.2
-
33
-
-
84872287714
-
Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites
-
Komatsu, M., Komatsu, K., Koiwai, H., Yamada, Y., Kozone, I., Izumikawa, M., et al. (2013). Engineered Streptomyces avermitilis host for heterologous expression of biosynthetic gene cluster for secondary metabolites. ACS Synth. Biol. 2, 384-396. doi: 10.1021/sb3001003
-
(2013)
ACS Synth. Biol
, vol.2
, pp. 384-396
-
-
Komatsu, M.1
Komatsu, K.2
Koiwai, H.3
Yamada, Y.4
Kozone, I.5
Izumikawa, M.6
-
34
-
-
85013703075
-
Inversion of extender unit selectivity in the erythromycin polyketide synthase by acyltransferase domain engineering
-
Koryakina, I., Kasey, C., McArthur, J. B., Lowell, A. N., Chemler, J. A., et al. (2016). Inversion of extender unit selectivity in the erythromycin polyketide synthase by acyltransferase domain engineering. ACS. Chem. Biol. 12, 114-123. doi: 10.1021/acschembio.6b00732
-
(2016)
ACS. Chem. Biol
, vol.12
, pp. 114-123
-
-
Koryakina, I.1
Kasey, C.2
McArthur, J.B.3
Lowell, A.N.4
Chemler, J.A.5
-
35
-
-
84987667504
-
Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers
-
Lam, S. J., O'Brien-Simpson, N. M., Pantarat, N., Sulistio, A., Wong, E. H., Chen, Y. Y., et al. (2016). Combating multidrug-resistant Gram-negative bacteria with structurally nanoengineered antimicrobial peptide polymers. Nat. Microbiol. 1:16162. doi: 10.1038/nmicrobiol.2016.162
-
(2016)
Nat. Microbiol
, vol.1
, pp. 16162
-
-
Lam, S.J.1
O'Brien-Simpson, N.M.2
Pantarat, N.3
Sulistio, A.4
Wong, E.H.5
Chen, Y.Y.6
-
36
-
-
84861440312
-
Systems metabolic engineering of microorganisms for natural and non-natural chemicals
-
Lee, J. W., Na, D., Park, J. M., Lee, J., Choi, S., and Lee, S. Y. (2012). Systems metabolic engineering of microorganisms for natural and non-natural chemicals. Nat. Chem. Biol. 8, 536-546. doi: 10.1038/nchembio.970
-
(2012)
Nat. Chem. Biol
, vol.8
, pp. 536-546
-
-
Lee, J.W.1
Na, D.2
Park, J.M.3
Lee, J.4
Choi, S.5
Lee, S.Y.6
-
37
-
-
84960425041
-
TarO-specific inhibitors of wall teichoic acid biosynthesis restore β-lactam efficacy against methicillin-resistant staphylococci
-
Lee, S. H., Wang, H., Labroli, M., Koseoglu, S., Zuck, P., Mayhood, T., et al. (2016). TarO-specific inhibitors of wall teichoic acid biosynthesis restore β-lactam efficacy against methicillin-resistant staphylococci. Sci. Transl. Med. 8, 329ra32. doi: 10.1126/scitranslmed.aad7364
-
(2016)
Sci. Transl. Med
, vol.8
-
-
Lee, S.H.1
Wang, H.2
Labroli, M.3
Koseoglu, S.4
Zuck, P.5
Mayhood, T.6
-
38
-
-
84926298894
-
Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis
-
Li, Y., Li, Z., Yamanaka, K., Xu, Y., Zhang, W., Vlamakis, H., et al. (2015). Directed natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilis. Sci. Rep. 5:9383. doi: 10.1038/srep09383
-
(2015)
Sci. Rep
, vol.5
, pp. 9383
-
-
Li, Y.1
Li, Z.2
Yamanaka, K.3
Xu, Y.4
Zhang, W.5
Vlamakis, H.6
-
39
-
-
84922937832
-
A new antibiotic kills pathogens without detectable resistance
-
Ling, L. L., Schneider, T., Peoples, A. J., Spoering, A. L., Engels, I., Conlon, B. P., et al. (2015). A new antibiotic kills pathogens without detectable resistance. Nature 517, 455-459. doi: 10.1038/nature14098
-
(2015)
Nature
, vol.517
, pp. 455-459
-
-
Ling, L.L.1
Schneider, T.2
Peoples, A.J.3
Spoering, A.L.4
Engels, I.5
Conlon, B.P.6
-
40
-
-
84937459775
-
Engineered biosynthesis of natural products in heterologous hosts
-
Luo, Y., Li, B. Z., Liu, D., Zhang, L., Chen, Y., Jia, B., et al. (2015). Engineered biosynthesis of natural products in heterologous hosts. Chem. Soc. Rev. 44, 5265-5290. doi: 10.1039/C5CS00025D
-
(2015)
Chem. Soc. Rev
, vol.44
, pp. 5265-5290
-
-
Luo, Y.1
Li, B.Z.2
Liu, D.3
Zhang, L.4
Chen, Y.5
Jia, B.6
-
41
-
-
78651517511
-
Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms
-
Medema, M. H., Breitling, R., Bovenberg, R., and Takano, E. (2011). Exploiting plug-and-play synthetic biology for drug discovery and production in microorganisms. Nat. Rev. Microbiol. 9, 131-137. doi: 10.1038/nrmicro2478
-
(2011)
Nat. Rev. Microbiol
, vol.9
, pp. 131-137
-
-
Medema, M.H.1
Breitling, R.2
Bovenberg, R.3
Takano, E.4
-
42
-
-
84857192122
-
Computational tools for the synthetic design of biochemical pathways
-
Medema, M. H., van Raaphorst, R., Takano, E., and Breitling, R. (2012). Computational tools for the synthetic design of biochemical pathways. Nat. Rev. Microbiol. 10, 191-202. doi: 10.1038/nrmicro2717
-
(2012)
Nat. Rev. Microbiol
, vol.10
, pp. 191-202
-
-
Medema, M.H.1
van Raaphorst, R.2
Takano, E.3
Breitling, R.4
-
43
-
-
85011948999
-
Antimicrobial peptides from fruits and their potential use as biotechnological tools-a review and outlook
-
Meneguetti, B. T., MacHado, L. D., Oshiro, K. G., Nogueira, M. L., Carvalho, C. M., and Franco, O. L. (2016). Antimicrobial peptides from fruits and their potential use as biotechnological tools-a review and outlook. Front. Microbiol. 7:2136. doi: 10.3389/fmicb.2016.02136
-
(2016)
Front. Microbiol
, vol.7
, pp. 2136
-
-
Meneguetti, B.T.1
MacHado, L.D.2
Oshiro, K.G.3
Nogueira, M.L.4
Carvalho, C.M.5
Franco, O.L.6
-
44
-
-
84858308226
-
Natural products as sources of new drugs over the 30 years from 1981 to 2010
-
Newman, D. J., and Cragg, G. M. (2012). Natural products as sources of new drugs over the 30 years from 1981 to 2010. J. Nat. Prod. 75, 311-335. doi: 10.1021/np200906s
-
(2012)
J. Nat. Prod
, vol.75
, pp. 311-335
-
-
Newman, D.J.1
Cragg, G.M.2
-
45
-
-
84889092982
-
From promise to practice, the role of synthetic biology in green chemistry
-
Nielsen, D. R., and Moon, T. S. (2013). From promise to practice, the role of synthetic biology in green chemistry. EMBO Rep. 14, 1034-1038. doi: 10.1038/embor.2013.178
-
(2013)
EMBO Rep
, vol.14
, pp. 1034-1038
-
-
Nielsen, D.R.1
Moon, T.S.2
-
46
-
-
84899052707
-
Engineering synergy in biotechnology
-
Nielsen, J., Fussenegger, M., Keasling, J., Lee, S. Y., Liao, J. C., Prather, K., et al. (2014). Engineering synergy in biotechnology. Nat. Chem. Biol. 10, 319-322. doi: 10.1038/nchembio.1519
-
(2014)
Nat. Chem. Biol
, vol.10
, pp. 319-322
-
-
Nielsen, J.1
Fussenegger, M.2
Keasling, J.3
Lee, S.Y.4
Liao, J.C.5
Prather, K.6
-
47
-
-
84959418965
-
A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species
-
Nyerges, á., Csörgo, B., Nagy, I., Bálint, B., Bihari, P., Lázár, V., et al. (2016). A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species. Proc. Natl. Acad. Sci. U.S.A. 113, 2502-2507. doi: 10.1073/pnas.1520040113
-
(2016)
Proc. Natl. Acad. Sci. U.S.A
, vol.113
, pp. 2502-2507
-
-
Nyerges, Á.1
Csörgo, B.2
Nagy, I.3
Bálint, B.4
Bihari, P.5
Lázár, V.6
-
48
-
-
84947910327
-
Activity-independent discovery of secondary metabolites using chemical elicitation and cheminformatic inference
-
Pimentel-Elardo, S. M., Sørensen, D., Ho, L., Ziko, M., Bueler, S. A., Lu, S., et al. (2015). Activity-independent discovery of secondary metabolites using chemical elicitation and cheminformatic inference. ACS Chem. Biol. 10, 2616-2623. doi: 10.1021/acschembio.5b00612
-
(2015)
ACS Chem. Biol
, vol.10
, pp. 2616-2623
-
-
Pimentel-Elardo, S.M.1
Sørensen, D.2
Ho, L.3
Ziko, M.4
Bueler, S.A.5
Lu, S.6
-
49
-
-
84884275445
-
Non-streptomycete actinomycetes nourish the current microbial antibiotic drug discovery
-
Polpass, A. J., and Jebakumar, S. R. D. (2013). Non-streptomycete actinomycetes nourish the current microbial antibiotic drug discovery. Front. Microbiol. 4:240. doi: 10.3389/fmicb.2013.00240
-
(2013)
Front. Microbiol
, vol.4
, pp. 240
-
-
Polpass, A.J.1
Jebakumar, S.R.D.2
-
50
-
-
84903753746
-
Old obstacles and new horizons for microbial chemical production
-
Porro, D., Branduardi, P., Sauer, M., and Mattanovich, D. (2014). Old obstacles and new horizons for microbial chemical production. Curr. Opin. Biotechnol. 30, 101-106. doi: 10.1016/j.copbio.2014.06.009
-
(2014)
Curr. Opin. Biotechnol
, vol.30
, pp. 101-106
-
-
Porro, D.1
Branduardi, P.2
Sauer, M.3
Mattanovich, D.4
-
51
-
-
84928165512
-
Targeted capture and heterologous expression of the Pseudoalteromonas alterochromide gene cluster in Escherichia coli represents a promising natural product exploratory platform
-
Ross, A. C., Gulland, L. E., Dorrestein, P. C., and Moore, B. S. (2014). Targeted capture and heterologous expression of the Pseudoalteromonas alterochromide gene cluster in Escherichia coli represents a promising natural product exploratory platform. ACS Synth. Biol. 4, 414-420. doi: 10.1021/sb500280q
-
(2014)
ACS Synth. Biol
, vol.4
, pp. 414-420
-
-
Ross, A.C.1
Gulland, L.E.2
Dorrestein, P.C.3
Moore, B.S.4
-
52
-
-
70349964350
-
Automated design of synthetic ribosome binding sites to control protein expression
-
Salis, H. M., Mirsky, E. A., and Voigt, C. A. (2009). Automated design of synthetic ribosome binding sites to control protein expression. Nat. Biotechnol. 27, 946-950. doi: 10.1038/nbt.1568
-
(2009)
Nat. Biotechnol
, vol.27
, pp. 946-950
-
-
Salis, H.M.1
Mirsky, E.A.2
Voigt, C.A.3
-
53
-
-
84969919894
-
Biogenic silver and gold nanoparticles synthesized using red ginseng root extract, and their applications
-
Singh, P., Kim, Y. J., Wang, C., Mathiyalagan, R., El-Agamy Farh, M., and Yang, D. C. (2016). Biogenic silver and gold nanoparticles synthesized using red ginseng root extract, and their applications. Artif. Cells Nanomed. Biotechnol. 44, 811-816. doi: 10.3109/21691401.2015.1008514
-
(2016)
Artif. Cells Nanomed. Biotechnol
, vol.44
, pp. 811-816
-
-
Singh, P.1
Kim, Y.J.2
Wang, C.3
Mathiyalagan, R.4
El-Agamy Farh, M.5
Yang, D.C.6
-
54
-
-
84869420041
-
Synthetic biology and metabolic engineering
-
Stephanopoulos, G. (2012). Synthetic biology and metabolic engineering. ACS Synth. Biol. 1, 514-525. doi: 10.1021/sb300094q
-
(2012)
ACS Synth. Biol
, vol.1
, pp. 514-525
-
-
Stephanopoulos, G.1
-
55
-
-
0025866296
-
Network rigidity and metabolic engineering in metabolite overproduction
-
Stephanopoulos, G., and Vallino, J. J. (1991). Network rigidity and metabolic engineering in metabolite overproduction. Science 252, 1675-1681. doi: 10.1126/science.1904627
-
(1991)
Science
, vol.252
, pp. 1675-1681
-
-
Stephanopoulos, G.1
Vallino, J.J.2
-
56
-
-
84915750322
-
Engineered nanoparticles for drug delivery in cancer therapy
-
Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., and Xia, Y. (2014). Engineered nanoparticles for drug delivery in cancer therapy. Angew. Chem. Int. Ed. Engl. 53, 12320-12364. doi: 10.1002/anie.201403036
-
(2014)
Angew. Chem. Int. Ed. Engl
, vol.53
, pp. 12320-12364
-
-
Sun, T.1
Zhang, Y.S.2
Pang, B.3
Hyun, D.C.4
Yang, M.5
Xia, Y.6
-
57
-
-
84874291605
-
Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents
-
Wang, H., Gill, C. J., Lee, S. H., Mann, P., Zuck, P., Meredith, T. C., et al. (2013). Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents. Chem. Biol. 20, 272-284. doi: 10.1016/j.chembiol.2012.11.013
-
(2013)
Chem. Biol
, vol.20
, pp. 272-284
-
-
Wang, H.1
Gill, C.J.2
Lee, S.H.3
Mann, P.4
Zuck, P.5
Meredith, T.C.6
-
58
-
-
84974717567
-
CRISPR/Cas9 in genome editing and beyond
-
Wang, H., Russa, M. L., and Qi, L. S. (2016). CRISPR/Cas9 in genome editing and beyond. Annu. Rev. Biochem. 85, 227-264. doi: 10.1146/annurev-biochem-060815-014607
-
(2016)
Annu. Rev. Biochem
, vol.85
, pp. 227-264
-
-
Wang, H.1
Russa, M.L.2
Qi, L.S.3
-
59
-
-
33947160920
-
Mutasynthesis-uniting chemistry and genetics for drug discovery
-
Weissman, K. J. (2007). Mutasynthesis-uniting chemistry and genetics for drug discovery. Trends Biotechnol. 25, 139-142. doi: 10.1016/j.tibtech.2007.02.004
-
(2007)
Trends Biotechnol
, vol.25
, pp. 139-142
-
-
Weissman, K.J.1
-
60
-
-
84957107829
-
Recent advances in engineering nonribosomal peptide assembly lines
-
Winn, M., Fyans, J. K., Zhuo, Y., and Micklefield, J. (2016). Recent advances in engineering nonribosomal peptide assembly lines. Nat. Prod. Rep. 33, 317-347. doi: 10.1039/C5NP00099H
-
(2016)
Nat. Prod. Rep
, vol.33
, pp. 317-347
-
-
Winn, M.1
Fyans, J.K.2
Zhuo, Y.3
Micklefield, J.4
-
61
-
-
80052594404
-
PLGA nanoparticles improve the oral bioavailability of curcumin in rats: characterizations and mechanisms
-
Xie, X., Tao, Q., Zou, Y., Zhang, F., Guo, M., Wang, Y., et al. (2011). PLGA nanoparticles improve the oral bioavailability of curcumin in rats: characterizations and mechanisms. J. Agric. Food Chem. 59, 9280-9289. doi: 10.1021/jf202135j
-
(2011)
J. Agric. Food Chem
, vol.59
, pp. 9280-9289
-
-
Xie, X.1
Tao, Q.2
Zou, Y.3
Zhang, F.4
Guo, M.5
Wang, Y.6
-
62
-
-
84945323376
-
Induced Production of halogenated epidithiodiketopiperazines by a marine-derived Trichoderma cf. brevicompactum with sodium halides
-
Yamazaki, H., Rotinsulu, H., Narita, R., Takahashi, R., and Namikoshi, M. (2015). Induced Production of halogenated epidithiodiketopiperazines by a marine-derived Trichoderma cf. brevicompactum with sodium halides. J. Nat. Prod. 78, 2319-2321. doi: 10.1021/acs.jnatprod.5b00669
-
(2015)
J. Nat. Prod
, vol.78
, pp. 2319-2321
-
-
Yamazaki, H.1
Rotinsulu, H.2
Narita, R.3
Takahashi, R.4
Namikoshi, M.5
-
63
-
-
84887540837
-
Multiplexing of combinatorial chemistry in antimycin biosynthesis: expansion of molecular diversity and utility
-
Yan, Y., Chen, J., Zhang, L., Zheng, Q., Han, Y., Zhang, H., et al. (2013). Multiplexing of combinatorial chemistry in antimycin biosynthesis: expansion of molecular diversity and utility. Angew. Chem. Int. Ed. Engl. 52, 12308-12312. doi: 10.1002/anie.201305569
-
(2013)
Angew. Chem. Int. Ed. Engl
, vol.52
, pp. 12308-12312
-
-
Yan, Y.1
Chen, J.2
Zhang, L.3
Zheng, Q.4
Han, Y.5
Zhang, H.6
-
64
-
-
84922832412
-
Synthetic fusion protein design and applications
-
Yu, K., Liu, C., Kim, B. G., and Lee, D. Y. (2015). Synthetic fusion protein design and applications. Biotechnol. Adv. 33, 155-164. doi: 10.1016/j.biotechadv.2014.11.005
-
(2015)
Biotechnol. Adv
, vol.33
, pp. 155-164
-
-
Yu, K.1
Liu, C.2
Kim, B.G.3
Lee, D.Y.4
-
65
-
-
78649386219
-
Complete biosynthesis of erythromycin A and designed analogs using E. coli as a heterologous host
-
Zhang, H., Wang, Y., Wu, J., Skalina, K., and Pfeifer, B. A. (2010). Complete biosynthesis of erythromycin A and designed analogs using E. coli as a heterologous host. Chem. Biol. 17, 1232-1240. doi: 10.1016/j.chembiol.2010.09.013
-
(2010)
Chem. Biol
, vol.17
, pp. 1232-1240
-
-
Zhang, H.1
Wang, Y.2
Wu, J.3
Skalina, K.4
Pfeifer, B.A.5
-
66
-
-
84979984723
-
The evolution of genome mining in microbes-a review
-
Ziemert, N., Alanjary, M., and Weber, T. (2016). The evolution of genome mining in microbes-a review. Nat. Prod. Rep. 33, 988-1005. doi: 10.1039/C6NP00025H
-
(2016)
Nat. Prod. Rep
, vol.33
, pp. 988-1005
-
-
Ziemert, N.1
Alanjary, M.2
Weber, T.3
-
67
-
-
84982710140
-
Human commensals producing a novel antibiotic impair pathogen colonization
-
Zipperer, A., Konnerth, M. C., Laux, C., Berscheid, A., Janek, D., Weidenmaier, C., et al. (2016). Human commensals producing a novel antibiotic impair pathogen colonization. Nature 535, 511-516. doi: 10.1038/nature18634
-
(2016)
Nature
, vol.535
, pp. 511-516
-
-
Zipperer, A.1
Konnerth, M.C.2
Laux, C.3
Berscheid, A.4
Janek, D.5
Weidenmaier, C.6
|