Mouse mammary tumor virus signal peptide uses a novel p97-dependent and Derlin-independent retrotranslocation mechanism to escape proteasomal degradation

mBio

Volumn 8, Issue 2, 2017, Pages

  Byun, Hyewon ^a   Das, Poulami ^a   Yu, Houqing ^a,b   Aleman, Alejandro ^a   Lozano, Mary M ^a   Matouschek, Andreas ^a   Dudley, Jaquelin P ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b HARVARD UNIVERSITY   (United States)

Author keywords

ERAD; Retrotranslocation; Retrovirus; Signal peptide

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DERLIN; MEMBRANE PROTEIN; PROTEASOME; PROTEIN P97; SIGNAL PEPTIDE; UNCLASSIFIED DRUG; DERLIN-1 PROTEIN, MOUSE; NUCLEAR PROTEIN; P97 ATPASE; VIRAL PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME DEGRADATION; ENZYME MECHANISM; HUMAN; HUMAN CELL; MOUSE MAMMARY TUMOR VIRUS; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN INTERACTION; UBIQUITINATION; CELL LINE; IMMUNE EVASION; IMMUNOLOGY; METABOLISM; PHYSIOLOGY; PROTEIN DEGRADATION; PROTEIN TRANSPORT;

ADENOSINE TRIPHOSPHATASES; CELL LINE; HUMANS; IMMUNE EVASION; MAMMARY TUMOR VIRUS, MOUSE; MEMBRANE PROTEINS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SORTING SIGNALS; PROTEIN TRANSPORT; PROTEOLYSIS; VIRAL PROTEINS;

EID: 85019133107     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00328-17     Document Type: Article

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