CD4 and BST-2/tetherin proteins retro-translocate from endoplasmic reticulum to cytosol as partially folded and multimeric molecules

Journal of Biological Chemistry

Volumn 289, Issue 1, 2014, Pages 1-12

  Petris, Gianluca ^a   Casini, Antonio ^b   Sasset, Linda ^a   Cesaratto, Francesca ^a   Bestagno, Marco ^a   Cereseto, Anna ^b   Burrone, Oscar R ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^b UNIVERSITY OF TRENTO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; CELL MEMBRANES; COVALENT BONDS; GLYCOPROTEINS; MOLECULES;

CELLULAR MEMBRANES; ENDOPLASMIC RETICULUM; GLYCOPHOSPHATIDYLINOSITOL; IMMUNOGLOBULIN-LIKE DOMAINS; MEMBRANE PROTEINS; PROTEASOMAL DEGRADATION; TRANS-MEMBRANE DOMAINS; TRANSMEMBRANE GLYCOPROTEINS;

PROTEINS;

CD4 ANTIGEN; MEMBRANE PROTEIN; TETHERIN; UNCLASSIFIED DRUG; BST2 PROTEIN, HUMAN; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; LEUKOCYTE ANTIGEN; MULTIPROTEIN COMPLEX; VIRUS PROTEIN; VPU PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

ARTICLE; BIOTINYLATION; CONTROLLED STUDY; CYTOSOL; DISULFIDE BOND; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATION; ENZYME INHIBITION; INTRACELLULAR TRANSPORT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN TRANSPORT; TRANSPORT KINETICS; GENETICS; HEK293 CELL LINE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; OXIDATION REDUCTION REACTION; PROTEIN MULTIMERIZATION; PROTEIN TERTIARY STRUCTURE;

ANTIGENS, CD; ANTIGENS, CD4; CYTOSOL; ENDOPLASMIC RETICULUM; GPI-LINKED PROTEINS; HEK293 CELLS; HIV-1; HUMAN IMMUNODEFICIENCY VIRUS PROTEINS; HUMANS; MULTIPROTEIN COMPLEXES; OXIDATION-REDUCTION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; VIRAL REGULATORY AND ACCESSORY PROTEINS;

EID: 84891724006     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.512368     Document Type: Article

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