-
1
-
-
79955526700
-
Mammalian EGF receptor activation by the rhomboid protease RHBDL2
-
Adrain C., Strisovsky K., Zettl M., Hu L., Lemberg M.K., Freeman M. Mammalian EGF receptor activation by the rhomboid protease RHBDL2. EMBO Rep. 2011, 12:421-427.
-
(2011)
EMBO Rep.
, vol.12
, pp. 421-427
-
-
Adrain, C.1
Strisovsky, K.2
Zettl, M.3
Hu, L.4
Lemberg, M.K.5
Freeman, M.6
-
2
-
-
34248371981
-
Sequence features of substrates required for cleavage by GlpG, an Escherichia coli rhomboid protease
-
Akiyama Y., Maegawa S. Sequence features of substrates required for cleavage by GlpG, an Escherichia coli rhomboid protease. Mol. Microbiol. 2007, 64:1028-1037.
-
(2007)
Mol. Microbiol.
, vol.64
, pp. 1028-1037
-
-
Akiyama, Y.1
Maegawa, S.2
-
3
-
-
79851515002
-
Protein dislocation from the ER
-
Bagola K., Mehnert M., Jarosch E., Sommer T. Protein dislocation from the ER. Biochim. Biophys. Acta 2011, 1808:925-936.
-
(2011)
Biochim. Biophys. Acta
, vol.1808
, pp. 925-936
-
-
Bagola, K.1
Mehnert, M.2
Jarosch, E.3
Sommer, T.4
-
4
-
-
53849102575
-
Regulation of ER-associated degradation via p97/VCP-interacting motif
-
Ballar P., Fang S. Regulation of ER-associated degradation via p97/VCP-interacting motif. Biochem. Soc. Trans. 2008, 36:818-822.
-
(2008)
Biochem. Soc. Trans.
, vol.36
, pp. 818-822
-
-
Ballar, P.1
Fang, S.2
-
5
-
-
24944583185
-
Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen
-
Bhamidipati A., Denic V., Quan E.M., Weissman J.S. Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen. Mol. Cell 2005, 19:741-751.
-
(2005)
Mol. Cell
, vol.19
, pp. 741-751
-
-
Bhamidipati, A.1
Denic, V.2
Quan, E.M.3
Weissman, J.S.4
-
6
-
-
0025012782
-
A peptide sequence confers retention and rapid degradation in the endoplasmic reticulum
-
Bonifacino J.S., Suzuki C.K., Klausner R.D. A peptide sequence confers retention and rapid degradation in the endoplasmic reticulum. Science 1990, 247:79-82.
-
(1990)
Science
, vol.247
, pp. 79-82
-
-
Bonifacino, J.S.1
Suzuki, C.K.2
Klausner, R.D.3
-
7
-
-
40949104848
-
Isolation of endoplasmic reticulum, mitochondria, and mitochondria-associated membrane fractions from transfected cells and from human cytomegalovirus-infected primary fibroblasts
-
Chapter 3, Unit 3, 27
-
Bozidis P., Williamson C.D., Colberg-Poley A.M. Isolation of endoplasmic reticulum, mitochondria, and mitochondria-associated membrane fractions from transfected cells and from human cytomegalovirus-infected primary fibroblasts. Curr. Protoc. Cell. Biol. 2007, Chapter 3, Unit 3, 27.
-
(2007)
Curr. Protoc. Cell. Biol.
-
-
Bozidis, P.1
Williamson, C.D.2
Colberg-Poley, A.M.3
-
8
-
-
84255169603
-
Defining human ERAD networks through an integrative mapping strategy
-
Christianson J.C., Olzmann J.A., Shaler T.A., Sowa M.E., Bennett E.J., Richter C.M., Tyler R.E., Greenblatt E.J., Wade Harper J., Kopito R.R. Defining human ERAD networks through an integrative mapping strategy. Nat. Cell Biol. 2011, 14:93-105.
-
(2011)
Nat. Cell Biol.
, vol.14
, pp. 93-105
-
-
Christianson, J.C.1
Olzmann, J.A.2
Shaler, T.A.3
Sowa, M.E.4
Bennett, E.J.5
Richter, C.M.6
Tyler, R.E.7
Greenblatt, E.J.8
Wade Harper, J.9
Kopito, R.R.10
-
9
-
-
33746208871
-
A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation
-
Denic V., Quan E.M., Weissman J.S. A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation. Cell 2006, 126:349-359.
-
(2006)
Cell
, vol.126
, pp. 349-359
-
-
Denic, V.1
Quan, E.M.2
Weissman, J.S.3
-
11
-
-
73149105938
-
Cleavage of a multispanning membrane protein by an intramembrane serine protease
-
Erez E., Bibi E. Cleavage of a multispanning membrane protein by an intramembrane serine protease. Biochemistry 2009, 48:12314-12322.
-
(2009)
Biochemistry
, vol.48
, pp. 12314-12322
-
-
Erez, E.1
Bibi, E.2
-
12
-
-
0035807839
-
The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum
-
Fang S., Ferrone M., Yang C., Jensen J.P., Tiwari S., Weissman A.M. The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum. Proc. Natl. Acad. Sci. USA 2001, 98:14422-14427.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14422-14427
-
-
Fang, S.1
Ferrone, M.2
Yang, C.3
Jensen, J.P.4
Tiwari, S.5
Weissman, A.M.6
-
13
-
-
80455164551
-
Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant alpha-1 antitrypsin from the endoplasmic reticulum
-
Greenblatt E.J., Olzmann J.A., Kopito R.R. Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant alpha-1 antitrypsin from the endoplasmic reticulum. Nat. Struct. Mol. Biol. 2011, 18:1147-1152.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 1147-1152
-
-
Greenblatt, E.J.1
Olzmann, J.A.2
Kopito, R.R.3
-
14
-
-
63649088506
-
Structure and mechanism of intramembrane protease
-
Ha Y. Structure and mechanism of intramembrane protease. Semin. Cell Dev. Biol. 2009, 20:240-250.
-
(2009)
Semin. Cell Dev. Biol.
, vol.20
, pp. 240-250
-
-
Ha, Y.1
-
15
-
-
0027221141
-
Charcot-Marie-Tooth neuropathy type 1B is associated with mutations of the myelin P0 gene
-
Hayasaka K., Himoro M., Sato W., Takada G., Uyemura K., Shimizu N., Bird T.D., Conneally P.M., Chance P.F. Charcot-Marie-Tooth neuropathy type 1B is associated with mutations of the myelin P0 gene. Nat. Genet. 1993, 5:31-34.
-
(1993)
Nat. Genet.
, vol.5
, pp. 31-34
-
-
Hayasaka, K.1
Himoro, M.2
Sato, W.3
Takada, G.4
Uyemura, K.5
Shimizu, N.6
Bird, T.D.7
Conneally, P.M.8
Chance, P.F.9
-
16
-
-
0030744415
-
The alpha chain of the T cell antigen receptor is degraded in the cytosol
-
Huppa J.B., Ploegh H.L. The alpha chain of the T cell antigen receptor is degraded in the cytosol. Immunity 1997, 7:113-122.
-
(1997)
Immunity
, vol.7
, pp. 113-122
-
-
Huppa, J.B.1
Ploegh, H.L.2
-
17
-
-
0037163084
-
A ubiquitin-interacting motif (UIM) is essential for Eps15 and Eps15R ubiquitination
-
Klapisz E., Sorokina I., Lemeer S., Pijnenburg M., Verkleij A.J., van Bergen en Henegouwen P.M. A ubiquitin-interacting motif (UIM) is essential for Eps15 and Eps15R ubiquitination. J. Biol. Chem. 2002, 277:30746-30753.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30746-30753
-
-
Klapisz, E.1
Sorokina, I.2
Lemeer, S.3
Pijnenburg, M.4
Verkleij, A.J.5
van Bergen en Henegouwen, P.M.6
-
18
-
-
0037264371
-
The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers
-
Koonin E.V., Makarova K.S., Rogozin I.B., Davidovic L., Letellier M.C., Pellegrini L. The rhomboids: a nearly ubiquitous family of intramembrane serine proteases that probably evolved by multiple ancient horizontal gene transfers. Genome Biol. 2003, 4:R19. 10.1186/gb-2003-4-3-r19.
-
(2003)
Genome Biol.
, vol.4
-
-
Koonin, E.V.1
Makarova, K.S.2
Rogozin, I.B.3
Davidovic, L.4
Letellier, M.C.5
Pellegrini, L.6
-
19
-
-
0035913906
-
Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila
-
Lee J.R., Urban S., Garvey C.F., Freeman M. Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila. Cell 2001, 107:161-171.
-
(2001)
Cell
, vol.107
, pp. 161-171
-
-
Lee, J.R.1
Urban, S.2
Garvey, C.F.3
Freeman, M.4
-
20
-
-
80051669175
-
Intramembrane proteolysis in regulated protein trafficking
-
Lemberg M.K. Intramembrane proteolysis in regulated protein trafficking. Traffic 2011, 12:1109-1118.
-
(2011)
Traffic
, vol.12
, pp. 1109-1118
-
-
Lemberg, M.K.1
-
21
-
-
35948982252
-
Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases
-
Lemberg M.K., Freeman M. Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases. Genome Res. 2007, 17:1634-1646.
-
(2007)
Genome Res.
, vol.17
, pp. 1634-1646
-
-
Lemberg, M.K.1
Freeman, M.2
-
22
-
-
3042616595
-
A membrane protein required for dislocation of misfolded proteins from the ER
-
Lilley B.N., Ploegh H.L. A membrane protein required for dislocation of misfolded proteins from the ER. Nature 2004, 429:834-840.
-
(2004)
Nature
, vol.429
, pp. 834-840
-
-
Lilley, B.N.1
Ploegh, H.L.2
-
23
-
-
33745207334
-
Signal peptide peptidase is required for dislocation from the endoplasmic reticulum
-
Loureiro J., Lilley B.N., Spooner E., Noriega V., Tortorella D., Ploegh H.L. Signal peptide peptidase is required for dislocation from the endoplasmic reticulum. Nature 2006, 441:894-897.
-
(2006)
Nature
, vol.441
, pp. 894-897
-
-
Loureiro, J.1
Lilley, B.N.2
Spooner, E.3
Noriega, V.4
Tortorella, D.5
Ploegh, H.L.6
-
24
-
-
84855952173
-
The gamma-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism
-
Merrick D., Chapin H., Baggs J.E., Yu Z., Somlo S., Sun Z., Hogenesch J.B., Caplan M.J. The gamma-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism. Dev. Cell 2012, 22:197-210.
-
(2012)
Dev. Cell
, vol.22
, pp. 197-210
-
-
Merrick, D.1
Chapin, H.2
Baggs, J.E.3
Yu, Z.4
Somlo, S.5
Sun, Z.6
Hogenesch, J.B.7
Caplan, M.J.8
-
25
-
-
0037470410
-
Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle
-
Molinari M., Calanca V., Galli C., Lucca P., Paganetti P. Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle. Science 2003, 299:1397-1400.
-
(2003)
Science
, vol.299
, pp. 1397-1400
-
-
Molinari, M.1
Calanca, V.2
Galli, C.3
Lucca, P.4
Paganetti, P.5
-
26
-
-
0036415895
-
Molecular analysis in Japanese patients with Charcot-Marie-Tooth disease: DGGE analysis for PMP22, MPZ, and Cx32/GJB1 mutations
-
Numakura C., Lin C., Ikegami T., Guldberg P., Hayasaka K. Molecular analysis in Japanese patients with Charcot-Marie-Tooth disease: DGGE analysis for PMP22, MPZ, and Cx32/GJB1 mutations. Hum. Mutat. 2002, 20:392-398.
-
(2002)
Hum. Mutat.
, vol.20
, pp. 392-398
-
-
Numakura, C.1
Lin, C.2
Ikegami, T.3
Guldberg, P.4
Hayasaka, K.5
-
27
-
-
31944450850
-
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
-
Oda Y., Okada T., Yoshida H., Kaufman R.J., Nagata K., Mori K. Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. J. Cell Biol. 2006, 172:383-393.
-
(2006)
J. Cell Biol.
, vol.172
, pp. 383-393
-
-
Oda, Y.1
Okada, T.2
Yoshida, H.3
Kaufman, R.J.4
Nagata, K.5
Mori, K.6
-
28
-
-
70350782523
-
Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein
-
Ray-Sinha A., Cross B.C., Mironov A., Wiertz E., High S. Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein. Mol. Membr. Biol. 2009, 26:448-464.
-
(2009)
Mol. Membr. Biol.
, vol.26
, pp. 448-464
-
-
Ray-Sinha, A.1
Cross, B.C.2
Mironov, A.3
Wiertz, E.4
High, S.5
-
29
-
-
79251602713
-
Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode
-
Santos J.M., Ferguson D.J., Blackman M.J., Soldati-Favre D. Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode. Science 2011, 331:473-477.
-
(2011)
Science
, vol.331
, pp. 473-477
-
-
Santos, J.M.1
Ferguson, D.J.2
Blackman, M.J.3
Soldati-Favre, D.4
-
30
-
-
82255161944
-
Road to ruin: targeting proteins for degradation in the endoplasmic reticulum
-
Smith M.H., Ploegh H.L., Weissman J.S. Road to ruin: targeting proteins for degradation in the endoplasmic reticulum. Science 2011, 334:1086-1090.
-
(2011)
Science
, vol.334
, pp. 1086-1090
-
-
Smith, M.H.1
Ploegh, H.L.2
Weissman, J.S.3
-
31
-
-
33846490396
-
M-AAA protease-driven membrane dislocation allows intramembrane cleavage by rhomboid in mitochondria
-
Tatsuta T., Augustin S., Nolden M., Friedrichs B., Langer T. m-AAA protease-driven membrane dislocation allows intramembrane cleavage by rhomboid in mitochondria. EMBO J. 2007, 26:325-335.
-
(2007)
EMBO J.
, vol.26
, pp. 325-335
-
-
Tatsuta, T.1
Augustin, S.2
Nolden, M.3
Friedrichs, B.4
Langer, T.5
-
32
-
-
0026502044
-
Carboxy terminally truncated forms of ribophorin I are degraded in pre-Golgi compartments by a calcium-dependent process
-
Tsao Y.S., Ivessa N.E., Adesnik M., Sabatini D.D., Kreibich G. Carboxy terminally truncated forms of ribophorin I are degraded in pre-Golgi compartments by a calcium-dependent process. J. Cell Biol. 1992, 116:57-67.
-
(1992)
J. Cell Biol.
, vol.116
, pp. 57-67
-
-
Tsao, Y.S.1
Ivessa, N.E.2
Adesnik, M.3
Sabatini, D.D.4
Kreibich, G.5
-
33
-
-
56749176947
-
One step at a time: endoplasmic reticulum-associated degradation
-
Vembar S.S., Brodsky J.L. One step at a time: endoplasmic reticulum-associated degradation. Nat. Rev. Mol. Cell Biol. 2008, 9:944-957.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 944-957
-
-
Vembar, S.S.1
Brodsky, J.L.2
-
34
-
-
21844440323
-
Unique features of the pre-T-cell receptor alpha-chain: not just a surrogate
-
von Boehmer H. Unique features of the pre-T-cell receptor alpha-chain: not just a surrogate. Nat. Rev. Immunol. 2005, 5:571-577.
-
(2005)
Nat. Rev. Immunol.
, vol.5
, pp. 571-577
-
-
von Boehmer, H.1
-
35
-
-
82255173966
-
The unfolded protein response: from stress pathway to homeostatic regulation
-
Walter P., Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011, 334:1081-1086.
-
(2011)
Science
, vol.334
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
36
-
-
57349136681
-
A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis
-
Wang Y., Guan X., Fok K.L., Li S., Zhang X., Miao S., Zong S., Koide S.S., Chan H.C., Wang L. A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosis. Cell. Mol. Life Sci. 2008, 65:3822-3829.
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 3822-3829
-
-
Wang, Y.1
Guan, X.2
Fok, K.L.3
Li, S.4
Zhang, X.5
Miao, S.6
Zong, S.7
Koide, S.S.8
Chan, H.C.9
Wang, L.10
-
37
-
-
0029915568
-
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol
-
Wiertz E.J., Jones T.R., Sun L., Bogyo M., Geuze H.J., Ploegh H.L. The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell 1996, 84:769-779.
-
(1996)
Cell
, vol.84
, pp. 769-779
-
-
Wiertz, E.J.1
Jones, T.R.2
Sun, L.3
Bogyo, M.4
Geuze, H.J.5
Ploegh, H.L.6
-
38
-
-
0032536903
-
Novel aspects of degradation of T cell receptor subunits from the endoplasmic reticulum (ER) in T cells: importance of oligosaccharide processing, ubiquitination, and proteasome-dependent removal from ER membranes
-
Yang M., Omura S., Bonifacino J.S., Weissman A.M. Novel aspects of degradation of T cell receptor subunits from the endoplasmic reticulum (ER) in T cells: importance of oligosaccharide processing, ubiquitination, and proteasome-dependent removal from ER membranes. J. Exp. Med. 1998, 187:835-846.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 835-846
-
-
Yang, M.1
Omura, S.2
Bonifacino, J.S.3
Weissman, A.M.4
-
39
-
-
0038487228
-
Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains
-
Ye Y., Meyer H.H., Rapoport T.A. Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains. J. Cell Biol. 2003, 162:71-84.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 71-84
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
-
40
-
-
3042677637
-
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
-
Ye Y., Shibata Y., Yun C., Ron D., Rapoport T.A. A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature 2004, 429:841-847.
-
(2004)
Nature
, vol.429
, pp. 841-847
-
-
Ye, Y.1
Shibata, Y.2
Yun, C.3
Ron, D.4
Rapoport, T.A.5
-
41
-
-
0032489524
-
Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a
-
Young P., Deveraux Q., Beal R.E., Pickart C.M., Rechsteiner M. Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a. J. Biol. Chem. 1998, 273:5461-5467.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5461-5467
-
-
Young, P.1
Deveraux, Q.2
Beal, R.E.3
Pickart, C.M.4
Rechsteiner, M.5
-
42
-
-
79953269767
-
Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling
-
Zettl M., Adrain C., Strisovsky K., Lastun V., Freeman M. Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling. Cell 2011, 145:79-91.
-
(2011)
Cell
, vol.145
, pp. 79-91
-
-
Zettl, M.1
Adrain, C.2
Strisovsky, K.3
Lastun, V.4
Freeman, M.5
|