Enantiocomplementary synthesis of γ-nitroketones using designed and evolved carboligases

Journal of the American Chemical Society

Volumn 139, Issue 1, 2017, Pages 103-106

  Garrabou, Xavier ^a   Verez, Rebecca ^a   Hilvert, Donald ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETONE; KETONES; STEREOCHEMISTRY;

ARTIFICIAL ENZYMES; ASYMMETRIC SYNTHESIS; BUILDING BLOCKES; COMPUTATIONAL DESIGN; DIRECTED EVOLUTION; DIVERGENT EVOLUTION; MICHAEL-TYPE REACTION; PROMISCUOUS ACTIVITY;

ENZYMES;

ENAMINE; FRUCTOSE BISPHOSPHATE ALDOLASE; KETONE; KETONE DERIVATIVE; LIGASE; MOLECULAR SCAFFOLD; NITROALKANE; LYASE; NITRO DERIVATIVE;

ARTICLE; ASYMMETRIC SYNTHESIS; BIOCATALYST; CHEMICAL BOND; ENZYME INACTIVATION; MICHAEL ADDITION; MUTAGENESIS; ONE POT SYNTHESIS; STEREOSELECTIVITY; SYNTHESIS; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; STEREOISOMERISM;

ALDEHYDE-LYASES; BIOCATALYSIS; KETONES; MOLECULAR STRUCTURE; NITRO COMPOUNDS; STEREOISOMERISM;

EID: 85018887825     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.6b11928     Document Type: Article

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