Fast Knoevenagel Condensations Catalyzed by an Artificial Schiff-Base-Forming Enzyme

Journal of the American Chemical Society

Volumn 138, Issue 22, 2016, Pages 6972-6974

  Garrabou, Xavier ^a   Wicky, Basile I M ^a   Hilvert, Donald ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CONDENSATION;

COMPUTATIONAL DESIGN; DIRECTED EVOLUTION; DIVERGENT EVOLUTION; HYDROPHOBIC POCKETS; KNOEVENAGEL CONDENSATION; METHYLENE DONOR; PRIMARY AND SECONDARY AMINE; REACTIVE LYSINES;

ENZYMES;

ALDEHYDE; AMINE; ENZYME VARIANT; FRUCTOSE BISPHOSPHATE ALDOLASE; LYSINE; SCHIFF BASE;

ALDOL REACTION; ARTICLE; BINDING SITE; BIOCATALYST; CATALYST; ELECTRON; ELECTROSPRAY MASS SPECTROMETRY; HYDROPHOBICITY; KNOEVENAGEL CONDENSATION; MICHAEL ADDITION; MICROTITER PLATE ASSAY; MUTAGENESIS; BIOCATALYSIS; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; DIRECTED MOLECULAR EVOLUTION; MOLECULAR MODEL;

ALDEHYDES; BIOCATALYSIS; COMPUTATIONAL BIOLOGY; DIRECTED MOLECULAR EVOLUTION; FRUCTOSE-BISPHOSPHATE ALDOLASE; LYSINE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SCHIFF BASES;

EID: 84974589189     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.6b00816     Document Type: Article

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