Exercise attenuates neurological deficits by stimulating a critical HSP70/NF-ΚB/IL-6/synapsin I axis in traumatic brain injury rats

Journal of Neuroinflammation

Volumn 14, Issue 1, 2017, Pages

  Chio, Chung Ching ^a   Lin, Hung Jung ^a,b   Tian, Yu Feng ^a,c   Chen, Yu Chieh ^b   Lin, Mao Tsun ^a   Lin, Cheng Hsien ^d   Chang, Ching Ping ^a,b,e   Hsu, Chien Chin ^a,b  

^a CHI MEI MEDICAL CENTER   (Taiwan)

^b SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^d Meridigen Biotech Co Ltd   (Taiwan)

^e TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Brain injury; Exercise; HSP70; IL 6; Neuroinflammation; Neuroprotection; Synapsin I

Indexed keywords

BASIC PROTEIN; BETA ACTIN; BONE MORPHOGENETIC PROTEIN 6; CD70 ANTIGEN; CXCL19 CHEMOKINE; FAS LIGAND; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GLYCOSYLPHOSPHATIDYLINOSITOL; HEAT SHOCK PROTEIN 70; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 16; INTERLEUKIN 18; INTERLEUKIN 22; INTERLEUKIN 6; INTERLEUKIN 7; LYMPHOTOXIN BETA; MACROPHAGE DERIVED CHEMOKINE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MACROPHAGE MIGRATION INHIBITION FACTOR; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; OSTEOGENIC PROTEIN 1; PRO PLATELET BASIC PROTEIN; SYNAPSIN I; THYMUS AND ACTIVATION REGULATED CHEMOKINE; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 11 BETA; UNCLASSIFIED DRUG; UNINDEXED DRUG; SYNAPSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD; BRAIN LEVEL; BRAIN PROTECTION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CORPUS STRIATUM; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPERIMENTAL TRAUMATIC BRAIN INJURY; FRONTAL CORTEX; GENE EXPRESSION; GENE SILENCING; HIPPOCAMPUS; HISTOPATHOLOGY; HYPOTHALAMUS; INFLAMMATION; KINESIOTHERAPY; MALE; NONHUMAN; PROMOTER REGION; QUANTITATIVE ANALYSIS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; WISTAR RAT; ANIMAL; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROCEDURES; RANDOMIZATION; TRAUMATIC BRAIN INJURY;

ANIMALS; BRAIN INJURIES, TRAUMATIC; HSP70 HEAT-SHOCK PROTEINS; INTERLEUKIN-6; MALE; NF-KAPPA B; PHYSICAL CONDITIONING, ANIMAL; RANDOM ALLOCATION; RATS; RATS, WISTAR; SYNAPSINS;

EID: 85018544424     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-017-0867-9     Document Type: Article

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