OPG/RANKL/RANK axis is a critical inflammatory signaling system in ischemic brain in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 22, 2014, Pages 8191-8196

  Shimamura, Munehisa ^a   Nakagami, Hironori ^a   Osako, Mariana K ^a,c   Kurinami, Hitomi ^a   Koriyama, Hiroshi ^a   Zhengda, Pang ^a   Tomioka, Hideki ^a   Tenma, Akiko ^a   Wakayama, Kouji ^b   Morishita, Ryuichi ^a  

^a OSAKA UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Cerebral ischemia; Immune cells; Neuroprotection

Indexed keywords

ARGINASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; MACROPHAGE; MICROGLIA; MOUSE; NERVE CELL CULTURE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UPREGULATION;

CEREBRAL ISCHEMIA; IMMUNE CELLS; NEUROPROTECTION;

ANIMALS; BRAIN; BRAIN EDEMA; BRAIN ISCHEMIA; CELL DEATH; CELLS, CULTURED; COCULTURE TECHNIQUES; CYTOKINES; ENCEPHALITIS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NEURONS; OSTEOPROTEGERIN; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84901853314     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1400544111     Document Type: Article

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