Melatonin administration to wild-type mice and nontreated NLRP3 mutant mice share similar inhibition of the inflammatory response during sepsis

Journal of Pineal Research

Volumn 63, Issue 1, 2017, Pages

  Rahim, Ibtissem ^a,b,c   Djerdjouri, Bahia ^c   Sayed, Ramy K ^a,d   Fernández Ortiz, Marisol ^a,e   Fernández Gil, Beatriz ^a,e   Hidalgo Gutiérrez, Agustín ^a,e   López, Luis C ^a,e,f   Escames, Germaine ^a,e,f   Reiter, Russel J ^g   Acuña Castroviejo, Darío ^a,e,f  

^a UNIVERSITY OF GRANADA   (Spain)

^b UNIVERSITY OF BLIDA   (Algeria)

^c UNIVERSITY OF SCIENCES AND TECHNOLOGY HOUARI BOUMEDIENE   (Algeria)

^d Sohag University   (Egypt)

^e UNIVERSITY OF GRANADA   (Spain)

^f Unidad de Gestión Clínica de Laboratorios Clínicos   (Spain)

^g UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

heart; melatonin; NF B; NLRP3 deficiency; NLRP3 inflammasome; sepsis

Indexed keywords

BETA ACTIN; COMPLEMENTARY DNA; CRYOPYRIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HISTONE H3; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MELATONIN; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; NUCLEAR RECEPTOR NR1D1; PER2 PROTEIN; RETINOID RELATED ORPHAN RECEPTOR ALPHA; RNA; SIRTUIN 1; TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK; TUMOR NECROSIS FACTOR; INFLAMMASOME;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ISOLATION; CIRCADIAN RHYTHM; CONTROLLED STUDY; CYTOSOL; CYTOSOLIC FRACTION; DRUG EFFICACY; ENZYME ACTIVATION; FEMALE; HISTOLOGY; IC50; INFLAMMATION; INNATE IMMUNITY; MORPHOLOGY; MOUSE; MOUSE STRAIN; NONHUMAN; PROTEIN CONTENT; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REPRESSOR GENE; SEPSIS; TURNOVER TIME; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CYTOLOGY; DRUG EFFECTS; GENETICS; HEART; METABOLISM; MUTATION; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; FEMALE; HEART; INFLAMMASOMES; MELATONIN; MICE; MICE, INBRED C57BL; MUTATION; MYOCARDIUM; MYOCYTES, CARDIAC; NF-KAPPA B; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; SEPSIS; SIGNAL TRANSDUCTION;

EID: 85018363813     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12410     Document Type: Article

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