NLRP3 Inflammasome knockout mice are protected against ischemic but not cisplatin-induced acute kidney injury

Journal of Pharmacology and Experimental Therapeutics

Volumn 346, Issue 3, 2013, Pages 465-472

  Kim, Hyun Jung ^b   Lee, Dong Won ^b   Ravichandran, Kameswaran ^b   Keys, Daniel O ^b   Akcay, Ali ^b   Nguyen, Quocan ^b   He, Zhibin ^b   Jani, Alkesh ^b   Ljubanovic, Danica ^a   Edelstein, Charles L ^b  

^a University of Zagreb School of Medicine   (Croatia)

^b UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN CONTAINING A CASPASE RECRUITMENT DOMAIN PROTEIN; CASPASE 5; CREATININE; CRYOPYRIN; CXCL1 CHEMOKINE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; NITROGEN; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LEUCINE RICH REPEAT AND PYRIN DOMAIN CONTAINING PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UREA;

ACUTE KIDNEY FAILURE; ACUTE KIDNEY TUBULE NECROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME ACTIVITY; IMMUNOBLOTTING; KIDNEY ISCHEMIA; KNOCKOUT MOUSE; MALE; MOLECULAR PATHOLOGY; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; UREA NITROGEN BLOOD LEVEL; WILD TYPE;

ACUTE KIDNEY INJURY; ANIMALS; ANTINEOPLASTIC AGENTS; CARRIER PROTEINS; CASPASE 1; CASPASES; CELL LINE, TUMOR; CISPLATIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; ISCHEMIA; KIDNEY; KIDNEY TUBULES, PROXIMAL; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTROPHIL INFILTRATION; RENAL CIRCULATION;

EID: 84882431324     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.113.205732     Document Type: Article

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