Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome

Journal of Pineal Research

Volumn 62, Issue 3, 2017, Pages

  Cao, Zhengwang ^a   Fang, Yiliang ^a   Lu, Yonghui ^a   Tan, Dunxian ^b   Du, Changhong ^a   Li, Yuming ^a   Ma, Qinlong ^a   Yu, Junmei ^a   Chen, Mengyan ^a   Zhou, Chao ^a   Pei, Liping ^a   Zhang, Lei ^a   Ran, Haiying ^a   He, Mindi ^a   Yu, Zhengping ^a   Zhou, Zhou ^a,c  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c GUANGXI UNIVERSITY   (China)

Author keywords

cadmium; liver injury; melatonin; NLRP3 inflammasome; TXNIP

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CADMIUM; CRYOPYRIN; INFLAMMASOME; MELATONIN; SMALL INTERFERING RNA; THIOREDOXIN INTERACTING PROTEIN; CARRIER PROTEIN; NLRP3 PROTEIN, MOUSE; THIOREDOXIN; TXNIP PROTEIN, MOUSE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; LIVER CELL; LIVER CELL DAMAGE; MALE; MOUSE; NONHUMAN; PROTEIN PROTEIN INTERACTION; TOXIC HEPATITIS; ANIMAL; BIOSYNTHESIS; CHEMICAL AND DRUG INDUCED LIVER INJURY; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ANIMALS; CADMIUM; CARRIER PROTEINS; CELL DEATH; CHEMICAL AND DRUG INDUCED LIVER INJURY; GENE EXPRESSION REGULATION; HEPATOCYTES; INFLAMMASOMES; INFLAMMATION; MALE; MELATONIN; MICE; MICE, KNOCKOUT; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; THIOREDOXINS;

EID: 85015085607     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/jpi.12389     Document Type: Article

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