Studies on the Bioactivities of ACE-inhibitory Peptides with Phenylalanine C-terminus Using 3D-QSAR, Molecular Docking and in vitro Evaluation

Molecular Informatics

Volumn 36, Issue 9, 2017, Pages

  Qi, Chunyan ^a   Lin, Guimei ^b   Zhang, Rong ^a   Wu, Wenjuan ^a  

^a GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

3D QSAR; ACE inhibitory peptides; in vitro evaluation; Molecular docking

Indexed keywords

AMINO ACIDS; COMPUTATIONAL CHEMISTRY; MOLECULAR GRAPHICS; MOLECULAR MODELING; PEPTIDES;

3D-QSAR; ACE-INHIBITORY; ACE-INHIBITORY PEPTIDE; ACTIVITY EVALUATIONS; C-TERMINUS; IN-VITRO EVALUATION; INHIBITORY PEPTIDES; MOLECULAR ACTIVITIES; MOLECULAR DOCKING; TRI-PEPTIDES;

BIOACTIVITY;

DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; PHENYLALANINE; TRIPEPTIDE DERIVATIVE; DIPEPTIDYL CARBOXYPEPTIDASE; PEPTIDE;

ARTICLE; BIOLOGICAL ACTIVITY; CARBOXY TERMINAL SEQUENCE; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE MOLECULAR SIMILARITY INDICES ANALYSIS; DRUG SCREENING; DRUG SYNTHESIS; IC50; IN VITRO STUDY; MOLECULAR DOCKING; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; BINDING SITE; CHEMISTRY; HUMAN; METABOLISM;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; BINDING SITES; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR DOCKING SIMULATION; PEPTIDES; PEPTIDYL-DIPEPTIDASE A; PHENYLALANINE; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85018259408     PISSN: 18681743     EISSN: 18681751     Source Type: Journal    
DOI: 10.1002/minf.201600157     Document Type: Article

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