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Volumn 2, Issue 4, 2012, Pages 130-136

Angiotensin I-converting enzyme inhibitory peptides: Inhibition mode, bioavailability, and antihypertensive effects

Author keywords

ACE inhibitory peptide; Antihypertensive effect; Bioavailability; Gastrointestinal digestion; Inhibition mode

Indexed keywords

ALANYLTRYPTOPHAN; ANGIOTENSIN I; ASPARAGINYLGLYCINE; ASPARAGINYLISOLEUCYLPROLYLPROLYLLEUCYLTHREONYLGLUTAMINYLTHREONYLPROLYLVALINE; ASPARAGINYLLEUCYLPROLINE; ASPARTYLLYSYLISOLEUCYLHISTIDINYLPROLYLPHENYLALANINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GASTROINTESTINAL ENZYME; INTESTINE ENZYME; ISOLEUCYLPHENYLALANYLLEUCINE; ISOLEUCYLTRYPTOPHAN; LEUCYLASPARAGINYLVALYLPROLYLGLYCYLGLUTAMYLISOLEUCYLVALYLGLUTAMIC ACID; LEUCYLGLYCYLPHENYLALANYLPROLYLTHREONYLTHREONYLLYSYLTHREONYLTYROSYLPHENYLALANYLPROPYLHISTIDINYLPHENYLALANINE; LEUCYLPHENYLALANINE; LYSYLVALYLARGINYLGLUTAMYLGLYCYLTHREONINE; LYSYLVALYLARGINYLGLUTAMYLGLYCYLTHREONYLTHREONYLTYROSINE; PEPTIDASE; PEPTIDE DERIVATIVE; PHENYLALANINETYROSINE; PHENYLALANYLLEUCINE; THREONYLLEUCYLTHREONYLASPARTYLTYROSINE; TRYPTOPHANYLALANINE; TRYPTOPHANYLLYSINE; TYROSYLASPARAGINE; TYROSYLLYSYLTYROSYLGLUTAMYLISOLEUCYLALANYLARGINYLARGININE; TYROSYLPROLYLISOLEUCINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALYLISOLEUCYLGLUTAMYLLYSYLTYROSYLPROLINE; VALYLVALYLTYROSYLPROLYLTRYPTOPHANYLTHREONYLGLUTAMINYLARGINYLPHENYLALANINE; VALYLVALYLTYROSYLPROLYLTRYPTOPHYLTHREONINE;

EID: 84871621268     PISSN: 22118020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomed.2012.06.005     Document Type: Review
Times cited : (120)

References (50)
  • 3
    • 0017578611 scopus 로고
    • Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents
    • Ondetti M.A., Rubin B., Cushman D.W. Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents. Science 1977, 4288:441-444.
    • (1977) Science , vol.4288 , pp. 441-444
    • Ondetti, M.A.1    Rubin, B.2    Cushman, D.W.3
  • 5
    • 0018305067 scopus 로고
    • Peptide inhibitors of angiotensin I-converting enzyme in digests of gelatin by bacterial collagenase
    • Oshima G., Shimabukuro H., Nagasawa K. Peptide inhibitors of angiotensin I-converting enzyme in digests of gelatin by bacterial collagenase. Biochim Biophys Acta 1979, 566:128-137.
    • (1979) Biochim Biophys Acta , vol.566 , pp. 128-137
    • Oshima, G.1    Shimabukuro, H.2    Nagasawa, K.3
  • 6
    • 0031055268 scopus 로고    scopus 로고
    • Identification of a novel angiotensin-I-converting enzyme inhibitory peptide corresponding to a tryptic fragment of bovine beta-lactoglobulin
    • Mullally M.M., Meisel H., FitzGerald R.J. Identification of a novel angiotensin-I-converting enzyme inhibitory peptide corresponding to a tryptic fragment of bovine beta-lactoglobulin. FEBS Lett 1997, 402:99-101.
    • (1997) FEBS Lett , vol.402 , pp. 99-101
    • Mullally, M.M.1    Meisel, H.2    FitzGerald, R.J.3
  • 7
    • 0030115607 scopus 로고    scopus 로고
    • Isolation from alpha-zein of thermolysin peptides with angiotensin I-converting enzyme inhibitory activity
    • Yano S., Suzuki K., Funatsu G. Isolation from alpha-zein of thermolysin peptides with angiotensin I-converting enzyme inhibitory activity. Biosci Biotechnol Biochem 1996, 60:661-663.
    • (1996) Biosci Biotechnol Biochem , vol.60 , pp. 661-663
    • Yano, S.1    Suzuki, K.2    Funatsu, G.3
  • 8
    • 12144288141 scopus 로고    scopus 로고
    • Purification of an ACE inhibitory peptide after hydrolysis of sunflower (Helianthus annuus L.) protein isolates
    • Megías C., del Mar Yust M., Pedroche J., Lquari H., Girón-Calle J., Alaiz M., et al. Purification of an ACE inhibitory peptide after hydrolysis of sunflower (Helianthus annuus L.) protein isolates. J Agric Food Chem 2004, 52:1928-1932.
    • (2004) J Agric Food Chem , vol.52 , pp. 1928-1932
    • Megías, C.1    del Mar Yust, M.2    Pedroche, J.3    Lquari, H.4    Girón-Calle, J.5    Alaiz, M.6
  • 9
    • 0034495131 scopus 로고    scopus 로고
    • Bioactive peptides derived from food proteins preventing lifestyle-related diseases
    • Yoshikawa M., Fujita H., Matoba N., Takenaka Y., Yamamoto T., Yamauchi R., et al. Bioactive peptides derived from food proteins preventing lifestyle-related diseases. Biofactors 2000, 12:143-146.
    • (2000) Biofactors , vol.12 , pp. 143-146
    • Yoshikawa, M.1    Fujita, H.2    Matoba, N.3    Takenaka, Y.4    Yamamoto, T.5    Yamauchi, R.6
  • 10
    • 0032807257 scopus 로고    scopus 로고
    • Preparation and characterization of novel bioactive peptides responsible for angiotensin I-converting enzyme inhibition from wheat germ
    • Matsui T., Li C.H., Osajima Y. Preparation and characterization of novel bioactive peptides responsible for angiotensin I-converting enzyme inhibition from wheat germ. J Pept Sci 1999, 5:289-297.
    • (1999) J Pept Sci , vol.5 , pp. 289-297
    • Matsui, T.1    Li, C.H.2    Osajima, Y.3
  • 11
    • 7044274319 scopus 로고    scopus 로고
    • Isolation of angiotensin I converting enzyme (ACE) inhibitor from fermented oyster sauce, Crassostrea gigas
    • Je J.Y., Park J.Y., Jung W.K., Park P.J., Kim S.K. Isolation of angiotensin I converting enzyme (ACE) inhibitor from fermented oyster sauce, Crassostrea gigas. Food Chem 2005, 90:809-814.
    • (2005) Food Chem , vol.90 , pp. 809-814
    • Je, J.Y.1    Park, J.Y.2    Jung, W.K.3    Park, P.J.4    Kim, S.K.5
  • 12
    • 68349102047 scopus 로고    scopus 로고
    • A novel angiotensin I converting enzyme inhibitory peptide from tuna frame protein hydrolysate and its antihypertensive effect in spontaneously hypertensive rats
    • Lee S.H., Qian Z.J., Kim S.K. A novel angiotensin I converting enzyme inhibitory peptide from tuna frame protein hydrolysate and its antihypertensive effect in spontaneously hypertensive rats. Food Chem 2010, 118:96-102.
    • (2010) Food Chem , vol.118 , pp. 96-102
    • Lee, S.H.1    Qian, Z.J.2    Kim, S.K.3
  • 13
    • 67349231325 scopus 로고    scopus 로고
    • A novel ACE inhibitory peptide isolated from Acaudina molpadioidea hydrolysate
    • Zhao Y., Li B., Dong S., Liu Z., Zhao X., Wang J., et al. A novel ACE inhibitory peptide isolated from Acaudina molpadioidea hydrolysate. Peptides 2009, 30:1028-1033.
    • (2009) Peptides , vol.30 , pp. 1028-1033
    • Zhao, Y.1    Li, B.2    Dong, S.3    Liu, Z.4    Zhao, X.5    Wang, J.6
  • 14
    • 35548970730 scopus 로고    scopus 로고
    • Antihypertensive effect of angiotensin I converting enzyme-inhibitory peptide from hydrolysates of Bigeye tuna dark muscle, Thunnus obesus
    • Qian Z.J., Je J.Y., Kim S.K. Antihypertensive effect of angiotensin I converting enzyme-inhibitory peptide from hydrolysates of Bigeye tuna dark muscle, Thunnus obesus. J Agric Food Chem 2007, 55:8398-8403.
    • (2007) J Agric Food Chem , vol.55 , pp. 8398-8403
    • Qian, Z.J.1    Je, J.Y.2    Kim, S.K.3
  • 15
    • 0033695674 scopus 로고    scopus 로고
    • Identification of an antihypertensive peptide from peptic digest of wakame (Undaria pinnatifida)
    • Suetsuna K., Nakano T. Identification of an antihypertensive peptide from peptic digest of wakame (Undaria pinnatifida). J Nutr Biochem 2000, 11:450-454.
    • (2000) J Nutr Biochem , vol.11 , pp. 450-454
    • Suetsuna, K.1    Nakano, T.2
  • 16
    • 0037048736 scopus 로고    scopus 로고
    • Angiotensin I-converting enzyme inhibitory peptides derived from wakame (Undaria pinnatifida) and their antihypertensive effect in spontaneously hypertensive rats
    • Sato M., Hosokawa T., Yamaguchi T., Nakano T., Muramoto K., Kahara T., et al. Angiotensin I-converting enzyme inhibitory peptides derived from wakame (Undaria pinnatifida) and their antihypertensive effect in spontaneously hypertensive rats. J Agric Food Chem 2002, 50:6245-6252.
    • (2002) J Agric Food Chem , vol.50 , pp. 6245-6252
    • Sato, M.1    Hosokawa, T.2    Yamaguchi, T.3    Nakano, T.4    Muramoto, K.5    Kahara, T.6
  • 17
    • 0031738304 scopus 로고    scopus 로고
    • Acein-1, a novel angiotensin-I-converting enzyme inhibitory peptide isolated from tryptic hydrolysate of human plasma
    • Nakagomi K., Fujimura A., Ebisu H., Sakai T., Sadakane Y., Fujii N., et al. Acein-1, a novel angiotensin-I-converting enzyme inhibitory peptide isolated from tryptic hydrolysate of human plasma. FEBS Lett 1998, 438:255-257.
    • (1998) FEBS Lett , vol.438 , pp. 255-257
    • Nakagomi, K.1    Fujimura, A.2    Ebisu, H.3    Sakai, T.4    Sadakane, Y.5    Fujii, N.6
  • 18
    • 76449112839 scopus 로고    scopus 로고
    • Antioxidative and angiotensin-I-converting enzyme inhibitory potential of a Pacific hake (Merluccius productus) fish protein hydrolysate subjected to simulated gastrointestinal digestion and Caco-2 cell permeation
    • Samaranayaka A.G.P., Kitts D.D., Li-Chan E.C.Y. Antioxidative and angiotensin-I-converting enzyme inhibitory potential of a Pacific hake (Merluccius productus) fish protein hydrolysate subjected to simulated gastrointestinal digestion and Caco-2 cell permeation. J Agric Food Chem 2010, 58:1535-1542.
    • (2010) J Agric Food Chem , vol.58 , pp. 1535-1542
    • Samaranayaka, A.G.P.1    Kitts, D.D.2    Li-Chan, E.C.Y.3
  • 19
    • 2142853106 scopus 로고    scopus 로고
    • Angiotensin I-converting enzyme inhibitory peptides isolated from tofuyo fermented soybean food
    • Kuba M., Tanaka K., Tawata S., Takeda Y., Yasuda M. Angiotensin I-converting enzyme inhibitory peptides isolated from tofuyo fermented soybean food. Biosci Biotechnol Biochem 2003, 67:1278-1283.
    • (2003) Biosci Biotechnol Biochem , vol.67 , pp. 1278-1283
    • Kuba, M.1    Tanaka, K.2    Tawata, S.3    Takeda, Y.4    Yasuda, M.5
  • 20
    • 51749125991 scopus 로고    scopus 로고
    • Purification and identification of a ACE inhibitory peptide from oyster proteins hydrolysate and the antihypertensive effect of hydrolysate in spontaneously hypertensive rats
    • Wang J.P., Hu J., Cui J., Bai X., Du Y., Miyaguchi Y., et al. Purification and identification of a ACE inhibitory peptide from oyster proteins hydrolysate and the antihypertensive effect of hydrolysate in spontaneously hypertensive rats. Food Chem 2008, 111:302-308.
    • (2008) Food Chem , vol.111 , pp. 302-308
    • Wang, J.P.1    Hu, J.2    Cui, J.3    Bai, X.4    Du, Y.5    Miyaguchi, Y.6
  • 21
    • 0030749136 scopus 로고    scopus 로고
    • Biochemical properties of regulatory peptides derived from milk proteins
    • Meisel H. Biochemical properties of regulatory peptides derived from milk proteins. Biopolymers 1997, 43:119-128.
    • (1997) Biopolymers , vol.43 , pp. 119-128
    • Meisel, H.1
  • 22
    • 0014959663 scopus 로고
    • Isolation of bradykinin-potentiating peptides from Bothrops jararaca venom
    • Ferreira S.H., Bartelt D.C., Greene L.J. Isolation of bradykinin-potentiating peptides from Bothrops jararaca venom. Biochemistry 1970, 9:2583-2593.
    • (1970) Biochemistry , vol.9 , pp. 2583-2593
    • Ferreira, S.H.1    Bartelt, D.C.2    Greene, L.J.3
  • 23
    • 43049107998 scopus 로고    scopus 로고
    • The antihypertensive effect of peptides: a novel alternative to drugs?
    • Hong F., Ming L., Yi S., Zhanxia L., Yongquan W., Chi L. The antihypertensive effect of peptides: a novel alternative to drugs?. Peptides 2008, 29:1062-1071.
    • (2008) Peptides , vol.29 , pp. 1062-1071
    • Hong, F.1    Ming, L.2    Yi, S.3    Zhanxia, L.4    Yongquan, W.5    Chi, L.6
  • 24
    • 0036219595 scopus 로고    scopus 로고
    • Characterization of inhibition and stability of soy-protein-derived angiotensin I-converting enzyme inhibitory peptides
    • Wu J., Ding X. Characterization of inhibition and stability of soy-protein-derived angiotensin I-converting enzyme inhibitory peptides. Food Res Int 2002, 35:367-375.
    • (2002) Food Res Int , vol.35 , pp. 367-375
    • Wu, J.1    Ding, X.2
  • 25
    • 44249117319 scopus 로고    scopus 로고
    • ACE-inhibitory peptides identified from the muscle protein hydrolysate of hard clam (Meretrix lusoria)
    • Tsai J.S., Chen J.L., Pan B.S. ACE-inhibitory peptides identified from the muscle protein hydrolysate of hard clam (Meretrix lusoria). Process Biochem 2008, 43:743-747.
    • (2008) Process Biochem , vol.43 , pp. 743-747
    • Tsai, J.S.1    Chen, J.L.2    Pan, B.S.3
  • 26
    • 33750041097 scopus 로고    scopus 로고
    • Isolation and characterization of angiotensin I-converting enzyme inhibitory peptides derived from porcine hemoglobin
    • Yu Y., Hu J., Miyaguchi Y., Bai X., Du Y., Lin B. Isolation and characterization of angiotensin I-converting enzyme inhibitory peptides derived from porcine hemoglobin. Peptides 2006, 27:2950-2956.
    • (2006) Peptides , vol.27 , pp. 2950-2956
    • Yu, Y.1    Hu, J.2    Miyaguchi, Y.3    Bai, X.4    Du, Y.5    Lin, B.6
  • 27
    • 0033823597 scopus 로고    scopus 로고
    • Production of angiotensin-I-converting-enzyme-inhibitory peptides in fermented milks started by Lactobacillus delbrueckii subsp. bulgaricus SS1 and Lactococcus lactis subsp. cremoris FT4
    • Gobbetti M., Ferranti P., Smacchi E., Goffredi F., Addeo F. Production of angiotensin-I-converting-enzyme-inhibitory peptides in fermented milks started by Lactobacillus delbrueckii subsp. bulgaricus SS1 and Lactococcus lactis subsp. cremoris FT4. Appl Environ Microbiol 2000, 66:3898-3904.
    • (2000) Appl Environ Microbiol , vol.66 , pp. 3898-3904
    • Gobbetti, M.1    Ferranti, P.2    Smacchi, E.3    Goffredi, F.4    Addeo, F.5
  • 28
    • 33644905566 scopus 로고    scopus 로고
    • Inhibition properties of dipeptides from salmon muscle hydrolysate on angiotensin I-converting enzyme
    • Ono S., Hosokawa M., Miyashita K., Takahashi K. Inhibition properties of dipeptides from salmon muscle hydrolysate on angiotensin I-converting enzyme. Int J Food Sci Technol 2006, 41:383-386.
    • (2006) Int J Food Sci Technol , vol.41 , pp. 383-386
    • Ono, S.1    Hosokawa, M.2    Miyashita, K.3    Takahashi, K.4
  • 29
    • 3242774456 scopus 로고    scopus 로고
    • Angiotensin I - converting enzyme inhibitory peptides derived from food proteins and their physiological and pharmacological effects
    • Li G.H., Le G.W., Shi Y.H., Shrestha S. Angiotensin I - converting enzyme inhibitory peptides derived from food proteins and their physiological and pharmacological effects. Nutr Res 2004, 24:469-486.
    • (2004) Nutr Res , vol.24 , pp. 469-486
    • Li, G.H.1    Le, G.W.2    Shi, Y.H.3    Shrestha, S.4
  • 30
    • 0020002135 scopus 로고
    • Enzymes of the renin-angiotensin system and their inhibitors
    • Ondetti M.A., Cushman D.W. Enzymes of the renin-angiotensin system and their inhibitors. Annu Rev Biochem 1982, 51:283-308.
    • (1982) Annu Rev Biochem , vol.51 , pp. 283-308
    • Ondetti, M.A.1    Cushman, D.W.2
  • 31
    • 0035087503 scopus 로고    scopus 로고
    • Angiotensin I-converting enzyme inhibitor from Grifola frondosa
    • Choi H.S., Cho H.Y., Yang H.C., Ra K.S., Suh H.J. Angiotensin I-converting enzyme inhibitor from Grifola frondosa. Food Res Int 2001, 34:177-182.
    • (2001) Food Res Int , vol.34 , pp. 177-182
    • Choi, H.S.1    Cho, H.Y.2    Yang, H.C.3    Ra, K.S.4    Suh, H.J.5
  • 32
    • 67650269402 scopus 로고    scopus 로고
    • Purification and characterization of angiotensin I converting enzyme inhibitory peptides from the rotifer, Brachionus rotundiformis
    • Lee J.K., Hong S., Jeon J.K., Kim S.K., Byun H.G. Purification and characterization of angiotensin I converting enzyme inhibitory peptides from the rotifer, Brachionus rotundiformis. Bioresour Technol 2009, 100:5255-5259.
    • (2009) Bioresour Technol , vol.100 , pp. 5255-5259
    • Lee, J.K.1    Hong, S.2    Jeon, J.K.3    Kim, S.K.4    Byun, H.G.5
  • 33
    • 61449170185 scopus 로고    scopus 로고
    • Mechanism of CYP2C9 inhibition by flavones and flavonols
    • Si D., Wang Y., Zhou Y.H., Guo Y., Wang J., Zhou H., et al. Mechanism of CYP2C9 inhibition by flavones and flavonols. Drug Metab Dispos 2009, 37:629-634.
    • (2009) Drug Metab Dispos , vol.37 , pp. 629-634
    • Si, D.1    Wang, Y.2    Zhou, Y.H.3    Guo, Y.4    Wang, J.5    Zhou, H.6
  • 34
    • 33646734243 scopus 로고    scopus 로고
    • One peptide derived from hen ovotransferrin as pro-drug to inhibit angiotensin converting enzyme
    • Lee N.Y., Cheng J.T., Enomoto T., Nakano Y. One peptide derived from hen ovotransferrin as pro-drug to inhibit angiotensin converting enzyme. J Food Drug Anal 2006, 14:31-35.
    • (2006) J Food Drug Anal , vol.14 , pp. 31-35
    • Lee, N.Y.1    Cheng, J.T.2    Enomoto, T.3    Nakano, Y.4
  • 35
    • 77956422979 scopus 로고    scopus 로고
    • Identification of oyster-derived hypotensive peptide acting as angiotensin-I-converting enzyme inhibitor
    • Shiozaki K., Shiozaki M., Masuda J., Yamauchi A., Ohwada S., Nakano T., et al. Identification of oyster-derived hypotensive peptide acting as angiotensin-I-converting enzyme inhibitor. Fish Sci 2010, 76:865-872.
    • (2010) Fish Sci , vol.76 , pp. 865-872
    • Shiozaki, K.1    Shiozaki, M.2    Masuda, J.3    Yamauchi, A.4    Ohwada, S.5    Nakano, T.6
  • 36
    • 60749131028 scopus 로고    scopus 로고
    • Isolation and characterization of a novel angiotensin I-converting enzyme (ACE) inhibitory peptide from the algae protein waste
    • Sheih I.C., Fang T.J., Wu T.K. Isolation and characterization of a novel angiotensin I-converting enzyme (ACE) inhibitory peptide from the algae protein waste. Food Chem 2009, 115:279-284.
    • (2009) Food Chem , vol.115 , pp. 279-284
    • Sheih, I.C.1    Fang, T.J.2    Wu, T.K.3
  • 37
    • 21544467786 scopus 로고    scopus 로고
    • Angiotensin I-converting enzyme inhibitory peptide from yellowfin sole (Limanda aspera) frame protein and its antihypertensive effect in spontaneously hypertensive rats
    • Jung W.K., Mendis E., Je J.Y., Park P.J., Son B.W., Kim H.C., et al. Angiotensin I-converting enzyme inhibitory peptide from yellowfin sole (Limanda aspera) frame protein and its antihypertensive effect in spontaneously hypertensive rats. Food Chem 2006, 94:26-32.
    • (2006) Food Chem , vol.94 , pp. 26-32
    • Jung, W.K.1    Mendis, E.2    Je, J.Y.3    Park, P.J.4    Son, B.W.5    Kim, H.C.6
  • 38
    • 84860997466 scopus 로고    scopus 로고
    • Inhibition mechanism and model of an angiotensin I-converting enzyme (ACE)-inhibitory hexapeptide from yeast (Saccharomyces cerevisiae)
    • Ni H., Li L., Liu G., Hu S.Q. Inhibition mechanism and model of an angiotensin I-converting enzyme (ACE)-inhibitory hexapeptide from yeast (Saccharomyces cerevisiae). PLoS One 2012, 7:e37077.
    • (2012) PLoS One , vol.7
    • Ni, H.1    Li, L.2    Liu, G.3    Hu, S.Q.4
  • 39
    • 0033860508 scopus 로고    scopus 로고
    • Classification and antihypertensive activity of angiotensin I-converting enzyme inhibitory peptides derived from food proteins
    • Fujita H., Yokoyama K., Yoshikawa M. Classification and antihypertensive activity of angiotensin I-converting enzyme inhibitory peptides derived from food proteins. J Food Sci 2000, 65:564-569.
    • (2000) J Food Sci , vol.65 , pp. 564-569
    • Fujita, H.1    Yokoyama, K.2    Yoshikawa, M.3
  • 40
    • 34047114512 scopus 로고    scopus 로고
    • Antihypertensive effect of rice protein hydrolysate with in vitro angiotensin I-converting enzyme inhibitory activity in spontaneously hypertensive rats
    • Li G.H., Qu M.R., Wan J.Z., You J.M. Antihypertensive effect of rice protein hydrolysate with in vitro angiotensin I-converting enzyme inhibitory activity in spontaneously hypertensive rats. Asia Pac J Clin Nutr 2007, 16(Suppl. 1):275-280.
    • (2007) Asia Pac J Clin Nutr , vol.16 , Issue.SUPPL. 1 , pp. 275-280
    • Li, G.H.1    Qu, M.R.2    Wan, J.Z.3    You, J.M.4
  • 41
    • 83455207972 scopus 로고    scopus 로고
    • Isolation and characterization of angiotensin I-converting enzyme inhibitor peptides derived from porcine hemoglobin
    • Ren Y., Wan D.-G., Lu X.-M., Chen L., Zhang T., Guo J.-L. Isolation and characterization of angiotensin I-converting enzyme inhibitor peptides derived from porcine hemoglobin. Sci Res Essays 2011, 6:6262-6269.
    • (2011) Sci Res Essays , vol.6 , pp. 6262-6269
    • Ren, Y.1    Wan, D.-G.2    Lu, X.-M.3    Chen, L.4    Zhang, T.5    Guo, J.-L.6
  • 42
    • 80051848862 scopus 로고    scopus 로고
    • Producibility and digestibility of antihypertensive β-casein tripeptides, Val-Pro-Pro and Ile-Pro-Pro, in the gastrointestinal tract: analyses using an in vitro model of mammalian gastrointestinal digestion
    • Ohsawa K., Satsu H., Ohki K., Enjoh M., Takano T., Shimizu M. Producibility and digestibility of antihypertensive β-casein tripeptides, Val-Pro-Pro and Ile-Pro-Pro, in the gastrointestinal tract: analyses using an in vitro model of mammalian gastrointestinal digestion. J Agric Food Chem 2008, 56:854-858.
    • (2008) J Agric Food Chem , vol.56 , pp. 854-858
    • Ohsawa, K.1    Satsu, H.2    Ohki, K.3    Enjoh, M.4    Takano, T.5    Shimizu, M.6
  • 43
    • 33244487664 scopus 로고    scopus 로고
    • Effect of simulated gastrointestinal digestion on the antihypertensive properties of ACE-inhibitory peptides derived from ovalbumin
    • Miguel M., Aleixandre M.A., Ramos M., López-Fandiño R. Effect of simulated gastrointestinal digestion on the antihypertensive properties of ACE-inhibitory peptides derived from ovalbumin. J Agric Food Chem 2006, 54:726-731.
    • (2006) J Agric Food Chem , vol.54 , pp. 726-731
    • Miguel, M.1    Aleixandre, M.A.2    Ramos, M.3    López-Fandiño, R.4
  • 44
    • 0030202780 scopus 로고    scopus 로고
    • Identification of an antihypertensive peptide from casein hydrolysate produced by a proteinase from Lactobacillus helveticus CP790
    • Maeno M., Yamamoto N., Takano T. Identification of an antihypertensive peptide from casein hydrolysate produced by a proteinase from Lactobacillus helveticus CP790. J Dairy Sci 1996, 79:1316-1321.
    • (1996) J Dairy Sci , vol.79 , pp. 1316-1321
    • Maeno, M.1    Yamamoto, N.2    Takano, T.3
  • 46
    • 0034492049 scopus 로고    scopus 로고
    • Milk protein-derived peptide inhibitors of angiotensin-I-converting enzyme
    • FitzGerald R.J., Meisel H. Milk protein-derived peptide inhibitors of angiotensin-I-converting enzyme. Br J Nutr 2000, 84(Suppl. 1):S33-S37.
    • (2000) Br J Nutr , vol.84 , Issue.SUPPL. 1
    • FitzGerald, R.J.1    Meisel, H.2
  • 48
    • 22444432899 scopus 로고    scopus 로고
    • Effects of dried bonito (katsuobushi) and captopril, an angiotensin I-converting enzyme inhibitor, on rat isolated aorta: a possible mechanism of antihypertensive action
    • Kouno K., Hirano S., Kuboki H., Kasai M., Hatae K. Effects of dried bonito (katsuobushi) and captopril, an angiotensin I-converting enzyme inhibitor, on rat isolated aorta: a possible mechanism of antihypertensive action. Biosci Biotechnol Biochem 2005, 69:911-915.
    • (2005) Biosci Biotechnol Biochem , vol.69 , pp. 911-915
    • Kouno, K.1    Hirano, S.2    Kuboki, H.3    Kasai, M.4    Hatae, K.5
  • 49
    • 0842324724 scopus 로고    scopus 로고
    • Influence of the lactokinin Ala-Leu-Pro-Met-His-Ile-Arg (ALPMHIR) on the release of endothelin-1 by endothelial cells
    • Maes W., Van Camp J., Vermeirssen V., Hemeryck M., Ketelslegers J.M., Schrezenmeir J., et al. Influence of the lactokinin Ala-Leu-Pro-Met-His-Ile-Arg (ALPMHIR) on the release of endothelin-1 by endothelial cells. Regul Pept 2004, 118:105-109.
    • (2004) Regul Pept , vol.118 , pp. 105-109
    • Maes, W.1    Van Camp, J.2    Vermeirssen, V.3    Hemeryck, M.4    Ketelslegers, J.M.5    Schrezenmeir, J.6
  • 50
    • 4444329422 scopus 로고    scopus 로고
    • Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance?
    • Touyz R.M. Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension: what is the clinical significance?. Hypertension 2004, 44:248-252.
    • (2004) Hypertension , vol.44 , pp. 248-252
    • Touyz, R.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.