-
1
-
-
84966397110
-
-
Chen, M., Chou, W. K. W., Toyomasu, T., Cane, D. E., and Christianson, D. W. (2016) ACS Chem. Biol. 11, 889 - 899
-
(2016)
ACS Chem. Biol.
, vol.11
, pp. 889-899
-
-
Chen, M.1
Chou, W.K.W.2
Toyomasu, T.3
Cane, D.E.4
Christianson, D.W.5
-
2
-
-
0030066640
-
Analgesic effects of myrrh
-
Dolara, P., Luceri, C., Ghelardini, C., Monserrat, C., Aiolli, S., Luceri, F., Lodovici, M., Menichetti, S., and Romanelli, M. N. (1996) Analgesic effects of myrrh Nature 379, 29 10.1038/379029a0
-
(1996)
Nature
, vol.379
, pp. 29
-
-
Dolara, P.1
Luceri, C.2
Ghelardini, C.3
Monserrat, C.4
Aiolli, S.5
Luceri, F.6
Lodovici, M.7
Menichetti, S.8
Romanelli, M.N.9
-
3
-
-
35148829942
-
Menthol: A refreshing look at this ancient compound
-
Patel, T., Ishiuji, Y., and Yosipovitch, G. (2007) Menthol: a refreshing look at this ancient compound J. Am. Acad. Dermatol. 57, 873-878 10.1016/j.jaad.2007.04.008
-
(2007)
J. Am. Acad. Dermatol.
, vol.57
, pp. 873-878
-
-
Patel, T.1
Ishiuji, Y.2
Yosipovitch, G.3
-
4
-
-
34250785114
-
The function of terpene natural products in the natural world
-
Gershenzon, J. and Dudareva, N. (2007) The function of terpene natural products in the natural world Nat. Chem. Biol. 3, 408-414 10.1038/nchembio.2007.5
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 408-414
-
-
Gershenzon, J.1
Dudareva, N.2
-
5
-
-
84911384806
-
Holy smoke in medieval funerary rites: Chemical fingerprints of frankincense in southern Belgian incense burners
-
Baeten, J., Deforce, K., Challe, S., De Vos, D., and Degryse, P. (2014) Holy smoke in medieval funerary rites: chemical fingerprints of frankincense in southern Belgian incense burners PLoS One 9 (11) e113142 10.1371/journal.pone.0113142
-
(2014)
PLoS One
, vol.9
, Issue.11
, pp. e113142
-
-
Baeten, J.1
Deforce, K.2
Challe, S.3
De Vos, D.4
Degryse, P.5
-
6
-
-
84987973327
-
Why do plants produce so many terpenoid compounds?
-
DOI
-
Pichersky, E. and Raguso, R. A. (2016) Why do plants produce so many terpenoid compounds? New Phytol., DOI: 10.1111/nph.14178.
-
(2016)
New Phytol.
-
-
Pichersky, E.1
Raguso, R.A.2
-
7
-
-
0000676652
-
The prenyl transfer reaction. Enzymic and mechanistic studies of the 1′-4 coupling reaction in the terpene biosynthetic pathway
-
Poulter, C. D. and Rilling, H. C. (1978) The prenyl transfer reaction. Enzymic and mechanistic studies of the 1′-4 coupling reaction in the terpene biosynthetic pathway Acc. Chem. Res. 11, 307-313 10.1021/ar50128a004
-
(1978)
Acc. Chem. Res.
, vol.11
, pp. 307-313
-
-
Poulter, C.D.1
Rilling, H.C.2
-
8
-
-
0000558630
-
Enzymatic formation of sesquiterpenes
-
Cane, D. E. (1990) Enzymatic formation of sesquiterpenes Chem. Rev. 90, 1089-1103 10.1021/cr00105a002
-
(1990)
Chem. Rev.
, vol.90
, pp. 1089-1103
-
-
Cane, D.E.1
-
9
-
-
0001836628
-
Cyclization Enzymes in the Biosynthesis of Monoterpenes, Sesquiterpenes, and Diterpenes
-
Springer-Verlag, Berlin, Germany
-
Davis, E. M. and Croteau, R. (2000) Cyclization Enzymes in the Biosynthesis of Monoterpenes, Sesquiterpenes, and Diterpenes, Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids, Vol. 209, pp 53-95, Springer-Verlag, Berlin, Germany.
-
(2000)
Biosynthesis: Aromatic Polyketides, Isoprenoids, Alkaloids
, vol.209
, pp. 53-95
-
-
Davis, E.M.1
Croteau, R.2
-
10
-
-
33646157726
-
Terpene synthases and the regulation, diversity and biological roles of terpene metabolism
-
Tholl, D. (2006) Terpene synthases and the regulation, diversity and biological roles of terpene metabolism Curr. Opin. Plant Biol. 9, 297-304 10.1016/j.pbi.2006.03.014
-
(2006)
Curr. Opin. Plant Biol.
, vol.9
, pp. 297-304
-
-
Tholl, D.1
-
11
-
-
33748601470
-
Structural biology and chemistry of the terpenoid cyclases
-
Christianson, D. W. (2006) Structural biology and chemistry of the terpenoid cyclases Chem. Rev. 106, 3412-3442 10.1021/cr050286w
-
(2006)
Chem. Rev.
, vol.106
, pp. 3412-3442
-
-
Christianson, D.W.1
-
12
-
-
83455210418
-
Sesquiterpene synthases: Passive catalysts or active players?
-
Miller, D. J. and Allemann, R. K. (2012) Sesquiterpene synthases: passive catalysts or active players? Nat. Prod. Rep. 29, 60-71 10.1039/C1NP00060H
-
(2012)
Nat. Prod. Rep.
, vol.29
, pp. 60-71
-
-
Miller, D.J.1
Allemann, R.K.2
-
13
-
-
84899764072
-
To gibberellins and beyond! Surveying the evolution of (di)terpenoid metabolism
-
Zi, J., Mafu, S., and Peters, R. J. (2014) To gibberellins and beyond! Surveying the evolution of (di)terpenoid metabolism Annu. Rev. Plant Biol. 65, 259-286 10.1146/annurev-arplant-050213-035705
-
(2014)
Annu. Rev. Plant Biol.
, vol.65
, pp. 259-286
-
-
Zi, J.1
Mafu, S.2
Peters, R.J.3
-
14
-
-
84973370129
-
Multi-domain terpenoid cyclase architecture and prospects for proximity in bifunctional catalysis
-
Chen, M., Harris, G. G., Pemberton, T. A., and Christianson, D. W. (2016) Multi-domain terpenoid cyclase architecture and prospects for proximity in bifunctional catalysis Curr. Opin. Struct. Biol. 41, 27-37 10.1016/j.sbi.2016.05.010
-
(2016)
Curr. Opin. Struct. Biol.
, vol.41
, pp. 27-37
-
-
Chen, M.1
Harris, G.G.2
Pemberton, T.A.3
Christianson, D.W.4
-
15
-
-
0030777210
-
Crystal structure of pentalenene synthase: Mechanistic insights on terpenoid cyclization reactions in biology
-
Lesburg, C. A., Zhai, G., Cane, D. E., and Christianson, D. W. (1997) Crystal structure of pentalenene synthase: Mechanistic insights on terpenoid cyclization reactions in biology Science 277, 1820-1824 10.1126/science.277.5333.1820
-
(1997)
Science
, vol.277
, pp. 1820-1824
-
-
Lesburg, C.A.1
Zhai, G.2
Cane, D.E.3
Christianson, D.W.4
-
16
-
-
0030796451
-
Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase
-
Starks, C. M., Back, K., Chappell, J., and Noel, J. P. (1997) Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase Science 277, 1815-1820 10.1126/science.277.5333.1815
-
(1997)
Science
, vol.277
, pp. 1815-1820
-
-
Starks, C.M.1
Back, K.2
Chappell, J.3
Noel, J.P.4
-
17
-
-
0030769202
-
Structure and function of a squalene cyclase
-
Wendt, K. U., Poralla, K., and Schulz, G. E. (1997) Structure and function of a squalene cyclase Science 277, 1811-1815 10.1126/science.277.5333.1811
-
(1997)
Science
, vol.277
, pp. 1811-1815
-
-
Wendt, K.U.1
Poralla, K.2
Schulz, G.E.3
-
18
-
-
78650991785
-
Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis
-
Köksal, M., Jin, Y., Coates, R. M., Croteau, R., and Christianson, D. W. (2011) Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis Nature 469, 116-120 10.1038/nature09628
-
(2011)
Nature
, vol.469
, pp. 116-120
-
-
Köksal, M.1
Jin, Y.2
Coates, R.M.3
Croteau, R.4
Christianson, D.W.5
-
19
-
-
79959374838
-
Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase
-
Köksal, M., Hu, H., Coates, R. M., Peters, R. J., and Christianson, D. W. (2011) Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase Nat. Chem. Biol. 7, 431-433 10.1038/nchembio.578
-
(2011)
Nat. Chem. Biol.
, vol.7
, pp. 431-433
-
-
Köksal, M.1
Hu, H.2
Coates, R.M.3
Peters, R.J.4
Christianson, D.W.5
-
20
-
-
84863164970
-
Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis
-
Zhou, K., Gao, Y., Hoy, J. A., Mann, F. M., Honzatko, R. B., and Peters, R. J. (2012) Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis J. Biol. Chem. 287, 6840-6850 10.1074/jbc.M111.337592
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 6840-6850
-
-
Zhou, K.1
Gao, Y.2
Hoy, J.A.3
Mann, F.M.4
Honzatko, R.B.5
Peters, R.J.6
-
21
-
-
84902449758
-
The first structure of a bacterial diterpene cyclase: CotB2
-
Janke, R., Görner, C., Hirte, M., Brück, T., and Loll, B. (2014) The first structure of a bacterial diterpene cyclase: CotB2 Acta Crystallogr., Sect. D: Biol. Crystallogr. 70, 1528-1537 10.1107/S1399004714005513
-
(2014)
Acta Crystallogr., Sect. D: Biol. Crystallogr.
, vol.70
, pp. 1528-1537
-
-
Janke, R.1
Görner, C.2
Hirte, M.3
Brück, T.4
Loll, B.5
-
22
-
-
0037180538
-
Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase
-
Whittington, D. A., Wise, M. L., Urbansky, M., Coates, R. M., Croteau, R., and Christianson, D. W. (2002) Bornyl diphosphate synthase: Structure and strategy for carbocation manipulation by a terpenoid cyclase Proc. Natl. Acad. Sci. U. S. A. 99, 15375-15380 10.1073/pnas.232591099
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 15375-15380
-
-
Whittington, D.A.1
Wise, M.L.2
Urbansky, M.3
Coates, R.M.4
Croteau, R.5
Christianson, D.W.6
-
23
-
-
0028964563
-
Cyclization of geranylgeranyl diphosphate to taxa-4(5),11(12)-diene is the committed step of Taxol biosynthesis in Pacific yew
-
Koepp, A. E., Hezari, M., Zajicek, J., Vogel, B. S., LaFever, R. E., Lewis, N. G., and Croteau, R. (1995) Cyclization of geranylgeranyl diphosphate to taxa-4(5),11(12)-diene is the committed step of Taxol biosynthesis in Pacific yew J. Biol. Chem. 270, 8686-8690 10.1074/jbc.270.15.8686
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 8686-8690
-
-
Koepp, A.E.1
Hezari, M.2
Zajicek, J.3
Vogel, B.S.4
LaFever, R.E.5
Lewis, N.G.6
Croteau, R.7
-
24
-
-
0029087870
-
Purification and characterization of taxa- 4(5),11(12)-diene synthase from Pacific yew (Taxus brevifolia) that catalyzes the first committed step of Taxol biosynthesis
-
Hezari, M., Lewis, N. G., and Croteau, R. (1995) Purification and characterization of taxa- 4(5),11(12)-diene synthase from Pacific yew (Taxus brevifolia) that catalyzes the first committed step of Taxol biosynthesis Arch. Biochem. Biophys. 322, 437-444 10.1006/abbi.1995.1486
-
(1995)
Arch. Biochem. Biophys.
, vol.322
, pp. 437-444
-
-
Hezari, M.1
Lewis, N.G.2
Croteau, R.3
-
25
-
-
0034234699
-
Heterologous expression and characterization of a ″pseudomature″ form of taxadiene synthase involved in Paclitaxel (Taxol) biosynthesis and evaluation of a potential intermediate and inhibitors of the multistep diterpene cyclization reaction
-
Williams, D. C., Wildung, M. R., Jin, A. Q., Dalal, D., Oliver, J. S., Coates, R. M., and Croteau, R. (2000) Heterologous expression and characterization of a ″pseudomature″ form of taxadiene synthase involved in Paclitaxel (Taxol) biosynthesis and evaluation of a potential intermediate and inhibitors of the multistep diterpene cyclization reaction Arch. Biochem. Biophys. 379, 137-146 10.1006/abbi.2000.1865
-
(2000)
Arch. Biochem. Biophys.
, vol.379
, pp. 137-146
-
-
Williams, D.C.1
Wildung, M.R.2
Jin, A.Q.3
Dalal, D.4
Oliver, J.S.5
Coates, R.M.6
Croteau, R.7
-
26
-
-
33847626336
-
Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi
-
Toyomasu, T., Tsukahara, M., Kaneko, A., Niida, R., Mitsuhashi, W., Dairi, T., Kato, N., and Sassa, T. (2007) Fusicoccins are biosynthesized by an unusual chimera diterpene synthase in fungi Proc. Natl. Acad. Sci. U. S. A. 104, 3084-3088 10.1073/pnas.0608426104
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 3084-3088
-
-
Toyomasu, T.1
Tsukahara, M.2
Kaneko, A.3
Niida, R.4
Mitsuhashi, W.5
Dairi, T.6
Kato, N.7
Sassa, T.8
-
27
-
-
67650330057
-
Transannular proton transfer in the cyclization of geranylgeranyl diphosphate to fusicoccadiene, a biosynthetic intermediate of fusicoccins
-
Toyomasu, T., Tsukahara, M., Kenmoku, H., Anada, M., Nitta, H., Ohkanda, J., Mitsuhashi, W., Sassa, T., and Kato, N. (2009) Transannular proton transfer in the cyclization of geranylgeranyl diphosphate to fusicoccadiene, a biosynthetic intermediate of fusicoccins Org. Lett. 11, 3044-3047 10.1021/ol901063s
-
(2009)
Org. Lett.
, vol.11
, pp. 3044-3047
-
-
Toyomasu, T.1
Tsukahara, M.2
Kenmoku, H.3
Anada, M.4
Nitta, H.5
Ohkanda, J.6
Mitsuhashi, W.7
Sassa, T.8
Kato, N.9
-
28
-
-
77952504491
-
Fusicoccin-A selectively induces apoptosis in tumor cells after interferon-a priming
-
de Vries-van Leeuwen, I. J., Kortekaas-Thijssen, C., Nzigou Mandouckou, J. A., Kas, S., Evidente, A., and de Boer, A. H. (2010) Fusicoccin-A selectively induces apoptosis in tumor cells after interferon-a priming Cancer Lett. 293, 198-206 10.1016/j.canlet.2010.01.009
-
(2010)
Cancer Lett.
, vol.293
, pp. 198-206
-
-
De Vries-Van Leeuwen, I.J.1
Kortekaas-Thijssen, C.2
Nzigou Mandouckou, J.A.3
Kas, S.4
Evidente, A.5
De Boer, A.H.6
-
29
-
-
84875764708
-
Fusicoccin A, a phytotoxic carbotricyclic diterpene glucoside of fungal origin, reduces proliferation and invasion of glioblastoma cells by targeting multiple tyrosine kinases
-
Bury, M., Andolfi, A., Rogister, B., Cimmino, A., Mégalizzi, V., Mathieu, V., Feron, O., Evidente, A., and Kiss, R. (2013) Fusicoccin A, a phytotoxic carbotricyclic diterpene glucoside of fungal origin, reduces proliferation and invasion of glioblastoma cells by targeting multiple tyrosine kinases Transl. Oncol. 6, 112-123 10.1593/tlo.12409
-
(2013)
Transl. Oncol.
, vol.6
, pp. 112-123
-
-
Bury, M.1
Andolfi, A.2
Rogister, B.3
Cimmino, A.4
Mégalizzi, V.5
Mathieu, V.6
Feron, O.7
Evidente, A.8
Kiss, R.9
-
30
-
-
0037416221
-
Structural view of a fungal toxin acting on a 14-3-3 regulatory complex
-
Wurtele, M., Jelich-Ottmann, C., Wittinghofer, A., and Oecking, C. (2003) Structural view of a fungal toxin acting on a 14-3-3 regulatory complex EMBO J. 22, 987-994 10.1093/emboj/cdg104
-
(2003)
EMBO J.
, vol.22
, pp. 987-994
-
-
Wurtele, M.1
Jelich-Ottmann, C.2
Wittinghofer, A.3
Oecking, C.4
-
31
-
-
84966397110
-
Structure and function of fusicoccadiene synthase, a hexameric bifunctional diterpene synthase
-
Chen, M., Chou, W. K. W., Toyomasu, T., Cane, D. E., and Christianson, D. W. (2016) Structure and function of fusicoccadiene synthase, a hexameric bifunctional diterpene synthase ACS Chem. Biol. 11, 889-899 10.1021/acschembio.5b00960
-
(2016)
ACS Chem. Biol.
, vol.11
, pp. 889-899
-
-
Chen, M.1
Chou, W.K.W.2
Toyomasu, T.3
Cane, D.E.4
Christianson, D.W.5
-
32
-
-
77952050895
-
Channeling by proximity: The catalytic advantages of active site colocalization using Brownian dynamics
-
Bauler, P., Huber, G., Leyh, T., and McCammon, J. A. (2010) Channeling by proximity: the catalytic advantages of active site colocalization using Brownian dynamics J. Phys. Chem. Lett. 1, 1332-1335 10.1021/jz1002007
-
(2010)
J. Phys. Chem. Lett.
, vol.1
, pp. 1332-1335
-
-
Bauler, P.1
Huber, G.2
Leyh, T.3
McCammon, J.A.4
-
33
-
-
84917699113
-
Enzyme clustering accelerates processing of intermediates through metabolic channeling
-
Castellana, M., Wilson, M. Z., Xu, Y., Joshi, P., Cristea, I. M., Rabinowitz, J. D., Gitai, Z., and Wingreen, N. S. (2014) Enzyme clustering accelerates processing of intermediates through metabolic channeling Nat. Biotechnol. 32, 1011-1018 10.1038/nbt.3018
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 1011-1018
-
-
Castellana, M.1
Wilson, M.Z.2
Xu, Y.3
Joshi, P.4
Cristea, I.M.5
Rabinowitz, J.D.6
Gitai, Z.7
Wingreen, N.S.8
-
34
-
-
84873391260
-
Identification of ophiobolin F synthase by a genome mining approach: A sesterterpene synthase from Aspergillus clavatus
-
Chiba, R., Minami, A., Gomi, K., and Oikawa, H. (2013) Identification of ophiobolin F synthase by a genome mining approach: a sesterterpene synthase from Aspergillus clavatus Org. Lett. 15, 594-597 10.1021/ol303408a
-
(2013)
Org. Lett.
, vol.15
, pp. 594-597
-
-
Chiba, R.1
Minami, A.2
Gomi, K.3
Oikawa, H.4
-
35
-
-
84941768267
-
Genome mining for sesterterpenes using bifunctional terpene synthases reveals a unified intermediate of di/sesterterpenes
-
Ye, Y., Minami, A., Mandi, A., Liu, C., Taniguchi, T., Kuzuyama, T., Monde, K., Gomi, K., and Oikawa, H. (2015) Genome mining for sesterterpenes using bifunctional terpene synthases reveals a unified intermediate of di/sesterterpenes J. Am. Chem. Soc. 137, 11846-11853 10.1021/jacs.5b08319
-
(2015)
J. Am. Chem. Soc.
, vol.137
, pp. 11846-11853
-
-
Ye, Y.1
Minami, A.2
Mandi, A.3
Liu, C.4
Taniguchi, T.5
Kuzuyama, T.6
Monde, K.7
Gomi, K.8
Oikawa, H.9
-
36
-
-
77956782362
-
Structure of isoprene synthase illuminates the chemical mechanism of teragram atmospheric carbon emission
-
Köksal, M., Zimmer, I., Schnitzler, J., and Christianson, D. W. (2010) Structure of isoprene synthase illuminates the chemical mechanism of teragram atmospheric carbon emission J. Mol. Biol. 402, 363-373 10.1016/j.jmb.2010.07.009
-
(2010)
J. Mol. Biol.
, vol.402
, pp. 363-373
-
-
Köksal, M.1
Zimmer, I.2
Schnitzler, J.3
Christianson, D.W.4
-
37
-
-
77749265076
-
Structure of epi-isozizaene synthase from Streptomyces coelicolor A3(2), a platform for new terpenoid cyclization templates
-
Aaron, J. A., Lin, X., Cane, D. E., and Christianson, D. W. (2010) Structure of epi-isozizaene synthase from Streptomyces coelicolor A3(2), a platform for new terpenoid cyclization templates Biochemistry 49, 1787-1797 10.1021/bi902088z
-
(2010)
Biochemistry
, vol.49
, pp. 1787-1797
-
-
Aaron, J.A.1
Lin, X.2
Cane, D.E.3
Christianson, D.W.4
-
38
-
-
0037453418
-
Retention index calculation without n-alkanes - The virtual carbon number
-
Harangi, J. (2003) Retention index calculation without n-alkanes-the virtual carbon number J. Chromatogr. A 993, 187-195 10.1016/S0021-9673(03)00320-0
-
(2003)
J. Chromatogr. A
, vol.993
, pp. 187-195
-
-
Harangi, J.1
-
39
-
-
84941882831
-
Molecular basis for stellatic acid biosynthesis: A genome mining approach for discovery of sesterterpene synthases
-
Matsuda, Y., Mitsuhashi, T., Quan, Z., and Abe, I. (2015) Molecular basis for stellatic acid biosynthesis: a genome mining approach for discovery of sesterterpene synthases Org. Lett. 17, 4644-4647 10.1021/acs.orglett.5b02404
-
(2015)
Org. Lett.
, vol.17
, pp. 4644-4647
-
-
Matsuda, Y.1
Mitsuhashi, T.2
Quan, Z.3
Abe, I.4
-
40
-
-
84955645373
-
An unusual chimeric diterpene synthase from Emericella variecolor and its functional conversion into a sesterterpene synthase by domain swapping
-
Qin, B., Matsuda, Y., Mori, T., Okada, M., Quan, Z., Mitsuhashi, T., Wakimoto, T., and Abe, I. (2016) An unusual chimeric diterpene synthase from Emericella variecolor and its functional conversion into a sesterterpene synthase by domain swapping Angew. Chem., Int. Ed. 55, 1658-1661 10.1002/anie.201509263
-
(2016)
Angew. Chem., Int. Ed.
, vol.55
, pp. 1658-1661
-
-
Qin, B.1
Matsuda, Y.2
Mori, T.3
Okada, M.4
Quan, Z.5
Mitsuhashi, T.6
Wakimoto, T.7
Abe, I.8
-
41
-
-
0000204904
-
Die Hydrolyse von Phosphaten und Pyrophosphaten Einiger Monoterpenalkohole
-
Cramer, F. and Rittersdorf, W. (1967) Die Hydrolyse von Phosphaten und Pyrophosphaten Einiger Monoterpenalkohole Tetrahedron 23, 3015-3022 10.1016/S0040-4020(01)83356-1
-
(1967)
Tetrahedron
, vol.23
, pp. 3015-3022
-
-
Cramer, F.1
Rittersdorf, W.2
-
42
-
-
0015137875
-
Nonenzymic formation of nerolidol from farnesyl pyrophosphate in the presence of bivalent cations
-
George-Nascimento, C., Pont-Lezica, R., and Cori, O. (1971) Nonenzymic formation of nerolidol from farnesyl pyrophosphate in the presence of bivalent cations Biochem. Biophys. Res. Commun. 45, 119-124 10.1016/0006-291X(71)90058-1
-
(1971)
Biochem. Biophys. Res. Commun.
, vol.45
, pp. 119-124
-
-
George-Nascimento, C.1
Pont-Lezica, R.2
Cori, O.3
-
43
-
-
0029956966
-
Identifying functional domains within terpene cyclases using a domain-swapping strategy
-
Back, K. and Chappell, J. (1996) Identifying functional domains within terpene cyclases using a domain-swapping strategy Proc. Natl. Acad. Sci. U. S. A. 93, 6841-6845 10.1073/pnas.93.13.6841
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 6841-6845
-
-
Back, K.1
Chappell, J.2
-
44
-
-
0028944573
-
Cloning and bacterial expression of a sesquiterpene cyclase from Hyoscyamus muticus and its molecular comparison to related terpene cyclases
-
Back, K. and Chappell, J. (1995) Cloning and bacterial expression of a sesquiterpene cyclase from Hyoscyamus muticus and its molecular comparison to related terpene cyclases J. Biol. Chem. 270, 7375-7381 10.1074/jbc.270.13.7375
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7375-7381
-
-
Back, K.1
Chappell, J.2
-
45
-
-
0037443614
-
Domain swapping of Citrus limon monoterpene synthases: Impact on enzymatic activity and product specificity
-
El Tamer, M. K., Lücker, J., Bosch, D., Verhoeven, H. A., Verstappen, F. W. A., Schwab, W., van Tunen, A. J., Voragen, A. G. J., de Maagd, R., and Bouwmeester, H. J. (2003) Domain swapping of Citrus limon monoterpene synthases: impact on enzymatic activity and product specificity Arch. Biochem. Biophys. 411, 196-203 10.1016/S0003-9861(02)00711-7
-
(2003)
Arch. Biochem. Biophys.
, vol.411
, pp. 196-203
-
-
El Tamer, M.K.1
Lücker, J.2
Bosch, D.3
Verhoeven, H.A.4
Verstappen, F.W.A.5
Schwab, W.6
Van Tunen, A.J.7
Voragen, A.G.J.8
De Maagd, R.9
Bouwmeester, H.J.10
-
46
-
-
0042664008
-
Alternative termination chemistries utilized by monoterpene cyclases: Chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases
-
Peters, R. J. and Croteau, R. B. (2003) Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases Arch. Biochem. Biophys. 417, 203-211 10.1016/S0003-9861(03)00347-3
-
(2003)
Arch. Biochem. Biophys.
, vol.417
, pp. 203-211
-
-
Peters, R.J.1
Croteau, R.B.2
-
47
-
-
0034723356
-
Functional Analysis of the Two Interacting Cyclase Domains in ent-Kaurene Synthase from the Fungus Phaeosphaeria sp. L487 and a Comparison with Cyclases from Higher Plants
-
Kawaide, H., Sassa, T., and Kamiya, Y. (2000) Functional Analysis of the Two Interacting Cyclase Domains in ent-Kaurene Synthase from the Fungus Phaeosphaeria sp. L487 and a Comparison with Cyclases from Higher Plants J. Biol. Chem. 275, 2276-2280 10.1074/jbc.275.4.2276
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 2276-2280
-
-
Kawaide, H.1
Sassa, T.2
Kamiya, Y.3
-
48
-
-
0037432331
-
Bifunctional Abietadiene Synthase: Mutual Structural Dependence of the Active Sites for Protonation-Initiated and Ionization-Initiated Cyclizations
-
Peters, R. J., Carter, O. A., Zhang, Y., Matthews, B. W., and Croteau, R. B. (2003) Bifunctional Abietadiene Synthase: Mutual Structural Dependence of the Active Sites for Protonation-Initiated and Ionization-Initiated Cyclizations Biochemistry 42, 2700-2707 10.1021/bi020492n
-
(2003)
Biochemistry
, vol.42
, pp. 2700-2707
-
-
Peters, R.J.1
Carter, O.A.2
Zhang, Y.3
Matthews, B.W.4
Croteau, R.B.5
-
49
-
-
0037452723
-
PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin
-
Gust, B., Challis, G. L., Fowler, K., Kieser, T., and Chater, K. F. (2003) PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin Proc. Natl. Acad. Sci. U. S. A. 100, 1541-1546 10.1073/pnas.0337542100
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 1541-1546
-
-
Gust, B.1
Challis, G.L.2
Fowler, K.3
Kieser, T.4
Chater, K.F.5
-
50
-
-
0037452696
-
Expression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesis
-
Cane, D. E. and Watt, R. M. (2003) Expression and mechanistic analysis of a germacradienol synthase from Streptomyces coelicolor implicated in geosmin biosynthesis Proc. Natl. Acad. Sci. U. S. A. 100, 1547-1551 10.1073/pnas.0337625100
-
(2003)
Proc. Natl. Acad. Sci. U. S. A.
, vol.100
, pp. 1547-1551
-
-
Cane, D.E.1
Watt, R.M.2
-
51
-
-
84948962778
-
Structural studies of geosmin synthase, a bifunctional sesquiterpene synthase with αα domain architecture that catalyzes a unique cyclization-fragmentation reaction sequence
-
Harris, G. G., Lombardi, P. M., Pemberton, T. A., Matsui, T., Weiss, T. M., Cole, K. E., Köksal, M., Murphy, F. V., IV, Vedula, L. S., Chou, W. K. W., Cane, D. E., and Christianson, D. W. (2015) Structural studies of geosmin synthase, a bifunctional sesquiterpene synthase with αα domain architecture that catalyzes a unique cyclization-fragmentation reaction sequence Biochemistry 54, 7142-7155 10.1021/acs.biochem.5b01143
-
(2015)
Biochemistry
, vol.54
, pp. 7142-7155
-
-
Harris, G.G.1
Lombardi, P.M.2
Pemberton, T.A.3
Matsui, T.4
Weiss, T.M.5
Cole, K.E.6
Köksal, M.7
Murphy, F.V.I.V.8
Vedula, L.S.9
Chou, W.K.W.10
Cane, D.E.11
Christianson, D.W.12
-
52
-
-
33745656143
-
Geosmin biosynthesis. Streptomyces coelicolor germacradienol/germacrene D synthase converts farnesyl diphosphate to geosmin
-
Jiang, J., He, X., and Cane, D. E. (2006) Geosmin biosynthesis. Streptomyces coelicolor germacradienol/germacrene D synthase converts farnesyl diphosphate to geosmin J. Am. Chem. Soc. 128, 8128-8129 10.1021/ja062669x
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 8128-8129
-
-
Jiang, J.1
He, X.2
Cane, D.E.3
-
53
-
-
35349006929
-
Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme
-
Jiang, J., He, X., and Cane, D. E. (2007) Biosynthesis of the earthy odorant geosmin by a bifunctional Streptomyces coelicolor enzyme Nat. Chem. Biol. 3, 711-715 10.1038/nchembio.2007.29
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 711-715
-
-
Jiang, J.1
He, X.2
Cane, D.E.3
-
54
-
-
77950362771
-
Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation
-
Chang, T.-H., Hsieh, F.-L., Ko, T.-P., Teng, K.-H., Liang, P.-H., and Wang, A. H.-J. (2010) Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation Plant Cell 22, 454-467 10.1105/tpc.109.071738
-
(2010)
Plant Cell
, vol.22
, pp. 454-467
-
-
Chang, T.-H.1
Hsieh, F.-L.2
Ko, T.-P.3
Teng, K.-H.4
Liang, P.-H.5
Wang, A.H.-J.6
-
55
-
-
34250688380
-
Following evolution's lead to a single residue switch for diterpene synthase product outcome
-
Xu, M., Wilderman, P. R., and Peters, R. J. (2007) Following evolution's lead to a single residue switch for diterpene synthase product outcome Proc. Natl. Acad. Sci. U. S. A. 104, 7397-7401 10.1073/pnas.0611454104
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 7397-7401
-
-
Xu, M.1
Wilderman, P.R.2
Peters, R.J.3
-
56
-
-
37549036742
-
A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase
-
Wilderman, P. R. and Peters, R. J. (2007) A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase J. Am. Chem. Soc. 129, 15736-15737 10.1021/ja074977g
-
(2007)
J. Am. Chem. Soc.
, vol.129
, pp. 15736-15737
-
-
Wilderman, P.R.1
Peters, R.J.2
-
57
-
-
42949168883
-
Increasing complexity of a diterpene synthase reaction with a single residue switch
-
Morrone, D., Xu, M., Fulton, D. B., Determan, M. K., and Peters, R. J. (2008) Increasing complexity of a diterpene synthase reaction with a single residue switch J. Am. Chem. Soc. 130, 5400-5401 10.1021/ja710524w
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 5400-5401
-
-
Morrone, D.1
Xu, M.2
Fulton, D.B.3
Determan, M.K.4
Peters, R.J.5
-
58
-
-
38949096144
-
Functional plasticity of paralogous diterpene synthases involved in conifer defense
-
Keeling, C. I., Weisshaar, S., Lin, R. P. C., and Bohlmann, J. (2008) Functional plasticity of paralogous diterpene synthases involved in conifer defense Proc. Natl. Acad. Sci. U. S. A. 105, 1085-1090 10.1073/pnas.0709466105
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 1085-1090
-
-
Keeling, C.I.1
Weisshaar, S.2
Lin, R.P.C.3
Bohlmann, J.4
-
59
-
-
84855950170
-
Mutational analysis of white spruce (Picea glauca) ent-kaurene synthase (PgKS) reveals common and distinct mechanisms of conifer diterpene synthases of general and specialized metabolism
-
Zerbe, P., Chiang, A., and Bohlmann, J. (2012) Mutational analysis of white spruce (Picea glauca) ent-kaurene synthase (PgKS) reveals common and distinct mechanisms of conifer diterpene synthases of general and specialized metabolism Phytochemistry 74, 30-39 10.1016/j.phytochem.2011.11.004
-
(2012)
Phytochemistry
, vol.74
, pp. 30-39
-
-
Zerbe, P.1
Chiang, A.2
Bohlmann, J.3
-
60
-
-
78650444156
-
Identification of the single amino acid involved in quenching the ent-kauranyl cation by a water molecule in ent-kaurene synthase of Physcomitrella patens
-
Kawaide, H., Hayashi, K.-i., Kawanabe, R., Sakigi, Y., Matsuo, A., Natsume, M., and Nozaki, H. (2011) Identification of the single amino acid involved in quenching the ent-kauranyl cation by a water molecule in ent-kaurene synthase of Physcomitrella patens FEBS J. 278, 123-133 10.1111/j.1742-4658.2010.07938.x
-
(2011)
FEBS J.
, vol.278
, pp. 123-133
-
-
Kawaide, H.1
Hayashi, K.-I.2
Kawanabe, R.3
Sakigi, Y.4
Matsuo, A.5
Natsume, M.6
Nozaki, H.7
-
61
-
-
84945549580
-
One amino acid makes the difference: The formation of ent-kaurene and 16α-hydroxy-ent-kaurane by diterpene synthases in poplar
-
Irmisch, S., Müller, A. T., Schmidt, L., Günther, J., Gershenzon, J., and Köllner, T. G. (2015) One amino acid makes the difference: the formation of ent-kaurene and 16α-hydroxy-ent-kaurane by diterpene synthases in poplar BMC Plant Biol. 15, 262 10.1186/s12870-015-0647-6
-
(2015)
BMC Plant Biol.
, vol.15
, pp. 262
-
-
Irmisch, S.1
Müller, A.T.2
Schmidt, L.3
Günther, J.4
Gershenzon, J.5
Köllner, T.G.6
-
62
-
-
84998882068
-
Extending a single residue switch for abbreviating catalysis in plant ent-kaurene synthases
-
Jia, M. and Peters, R. J. (2016) Extending a single residue switch for abbreviating catalysis in plant ent-kaurene synthases Front. Plant Sci. 7, 1765 10.3389/fpls.2016.01765
-
(2016)
Front. Plant Sci.
, vol.7
, pp. 1765
-
-
Jia, M.1
Peters, R.J.2
-
63
-
-
85015794844
-
A pair of residues that interactively affect diterpene synthase product outcome
-
Jia, M., Zhou, K., Tufts, S., Schulte, S., and Peters, R. J. (2017) A pair of residues that interactively affect diterpene synthase product outcome ACS Chem. Biol. 12, 862-867 10.1021/acschembio.6b01075
-
(2017)
ACS Chem. Biol.
, vol.12
, pp. 862-867
-
-
Jia, M.1
Zhou, K.2
Tufts, S.3
Schulte, S.4
Peters, R.J.5
-
64
-
-
20344394434
-
-
Jin, Q., Williams, D. C., Hezari, M., Croteau, R., and Coates, R. M. (2005) J. Org. Chem. 70, 4667-4675 10.1021/jo0502091
-
(2005)
J. Org. Chem.
, vol.70
, pp. 4667-4675
-
-
Jin, Q.1
Williams, D.C.2
Hezari, M.3
Croteau, R.4
Coates, R.M.5
|