Bifunctional abietadiene synthase: Mutual structural dependence of the active sites for protonation-initiated and ionization-initiated cyclizations

Biochemistry

Volumn 42, Issue 9, 2003, Pages 2700-2707

  Peters, Reuben J ^a,c   Carter, Ora A ^a   Zhang, Yan ^b,d   Matthews, Brian W ^b   Croteau, Rodney B ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b UNIVERSITY OF OREGON   (United States)

^c IOWA STATE UNIVERSITY   (United States)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; ENZYMES; IONIZATION; ORGANIC ACIDS;

RESIN ACIDS;

BIOCHEMISTRY;

ABIETADIENE SYNTHASE; COPALYL DIPHOSPHATE; DITERPENOID; FARNESYL TRANS TRANSFERASE; PYROPHOSPHATE; RESIN; SYNTHETASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CYCLIZATION; ENZYME ACTIVE SITE; ENZYME ASSAY; ENZYME BINDING; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SYNTHESIS; GENE FUSION; GENE INSERTION; IONIZATION; PRIORITY JOURNAL; PROTON TRANSPORT;

ABIES; BINDING SITES; CATALYSIS; DITERPENES; DNA MUTATIONAL ANALYSIS; IONS; ISOMERASES; MODELS, CHEMICAL; MODELS, MOLECULAR; MULTIENZYME COMPLEXES; PEPTIDE FRAGMENTS; PHOSPHORIC ACID ESTERS; PLANT PROTEINS; POLYISOPRENYL PHOSPHATES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTONS; SEQUENCE DELETION; STRUCTURE-ACTIVITY RELATIONSHIP;

ABIES GRANDIS;

EID: 0037432331     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi020492n     Document Type: Article

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