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Volumn 18, Issue 7, 2017, Pages 423-436

The development and functions of multiciliated epithelia

Author keywords

[No Author keywords available]

Indexed keywords

CELL DIFFERENTIATION; CELL FATE; CELL MATURATION; CELL MEMBRANE; CELL POLARITY; CENTRAL NERVOUS SYSTEM; CENTRIOLE; CEREBROSPINAL FLUID; CILIATED EPITHELIUM; EAR; EPENDYMA CELL; EPIDERMIS; EPITHELIUM CELL; GENITAL SYSTEM; HUMAN; KINETOSOME; LUNG; MOLECULAR DOCKING; MOTILE CILIUM; MULTICILIATED CELL; NONHUMAN; NOSE; OVIDUCT; POLARIZATION; PRIORITY JOURNAL; REVIEW; STEM CELL; THROAT; TRACHEA; ANIMAL; CILIUM; CYTOLOGY; EPITHELIUM; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY; VERTEBRATE;

EID: 85017430116     PISSN: 14710072     EISSN: 14710080     Source Type: Journal    
DOI: 10.1038/nrm.2017.21     Document Type: Review
Times cited : (275)

References (314)
  • 1
    • 0001055757 scopus 로고
    • Development of cilia in embryos of the turbellarian Macrostomum
    • Tyler, S. Development of cilia in embryos of the turbellarian Macrostomum. Hydrobiologia 84, 231-239 (1981).
    • (1981) Hydrobiologia , vol.84 , pp. 231-239
    • Tyler, S.1
  • 2
    • 18844479870 scopus 로고
    • Development of macrociliary cells in Beroe
    • Tamm, S. L. & Tamm, S. Development of macrociliary cells in Beroe. J. Cell Sci. 89, 81-95 (1988).
    • (1988) J. Cell Sci , vol.89 , pp. 81-95
    • Tamm, S.L.1    Tamm, S.2
  • 3
    • 0015383295 scopus 로고
    • Ciliary activity and the origin of metachrony in Paramecium: Effects of increased viscosity
    • Machemer, H. Ciliary activity and the origin of metachrony in Paramecium: effects of increased viscosity. J. Exp. Biol. 57, 239-259 (1972).
    • (1972) J. Exp. Biol , vol.57 , pp. 239-259
    • Machemer, H.1
  • 4
  • 6
    • 85011556783 scopus 로고    scopus 로고
    • The central apparatus of cilia and eukaryotic flagella
    • Loreng, T. D. & Smith, E. F. The central apparatus of cilia and eukaryotic flagella. Cold Spring Harb. Perspect. Biol. 9, a028118 (2016).
    • (2016) Cold Spring Harb. Perspect. Biol , vol.9 , pp. a028118
    • Loreng, T.D.1    Smith, E.F.2
  • 7
    • 0013845757 scopus 로고
    • An up-To-now unknown way of centriole propagation
    • in German)
    • Stockinger, L. & Cireli, E. An up-To-now unknown way of centriole propagation. Z. Zellforsch. Mikrosk. Anat. 68, 733-740 (in German) (1965).
    • (1965) Z. Zellforsch. Mikrosk. Anat , vol.68 , pp. 733-740
    • Stockinger, L.1    Cireli, E.2
  • 8
    • 0014232224 scopus 로고
    • An electron microscopic study of ciliogenesis in developing epidermis and trachea in the embryo of
    • Steinman, R. M. An electron microscopic study of ciliogenesis in developing epidermis and trachea in the embryo of Xenopus laevis. Am. J. Anat. 122, 19-55 (1968).
    • (1968) Xenopus Laevis. Am. J. Anat , vol.122 , pp. 19-55
    • Steinman, R.M.1
  • 9
    • 0014291368 scopus 로고
    • Reconstructions of centriole formation and ciliogenesis in mammalian lungs
    • Sorokin, S. P. Reconstructions of centriole formation and ciliogenesis in mammalian lungs. J. Cell Sci. 3, 207-230 (1968).
    • (1968) J. Cell Sci , vol.3 , pp. 207-230
    • Sorokin, S.P.1
  • 10
    • 0015141393 scopus 로고
    • Centriole morphogenesis in developing ciliated epithelium of the mouse oviduct
    • Dirksen, E. R. Centriole morphogenesis in developing ciliated epithelium of the mouse oviduct. J. Cell Biol. 51, 286-302 (1971).
    • (1971) J. Cell Biol , vol.51 , pp. 286-302
    • Dirksen, E.R.1
  • 11
    • 0015096359 scopus 로고
    • The formation of basal bodies (centrioles) in the rhesus monkey oviduct
    • Anderson, R. & Brenner, R. The formation of basal bodies (centrioles) in the rhesus monkey oviduct. J. Cell Biol. 50, 10-34 (1971).
    • (1971) J. Cell Biol , vol.50 , pp. 10-34
    • Anderson, R.1    Brenner, R.2
  • 12
    • 0016804501 scopus 로고
    • Estradiol-induced differentiation of the oviductal epithelium in ovariectomized cats
    • Verhage, H. G. & Brenner, R. M. Estradiol-induced differentiation of the oviductal epithelium in ovariectomized cats. Biol. Reprod. 13, 104-111 (1975).
    • (1975) Biol. Reprod , vol.13 , pp. 104-111
    • Verhage, H.G.1    Brenner, R.M.2
  • 13
    • 0018734142 scopus 로고
    • Cyclic changes in ciliation, secretion and cell height of the oviductal epithelium in women
    • Verhage, H. G., Bareither, M. L., Jaffe, R. C. & Akbar, M. Cyclic changes in ciliation, secretion and cell height of the oviductal epithelium in women. Am. J. Anat. 156, 505-521 (1979).
    • (1979) Am. J. Anat , vol.156 , pp. 505-521
    • Verhage, H.G.1    Bareither, M.L.2    Jaffe, R.C.3    Akbar, M.4
  • 14
    • 0014632354 scopus 로고
    • Centriole replication during ciliogenesis in the chick tracheal epithelium
    • Kalnins, V. I. & Porter, K. R. Centriole replication during ciliogenesis in the chick tracheal epithelium. Z. Zellforsch. Mikrosk. Anat. 100, 1-30 (1969).
    • (1969) Z. Zellforsch. Mikrosk. Anat , vol.100 , pp. 1-30
    • Kalnins, V.I.1    Porter, K.R.2
  • 15
    • 0015458776 scopus 로고
    • Procentrioles in ciliating and ciliated cells of chick trachea
    • Kalnins, V. I., Chung, C. K. & Turnbull, C. Procentrioles in ciliating and ciliated cells of chick trachea. Z. Zellforsch. Mikrosk. Anat. 135, 461-471 (1972).
    • (1972) Z. Zellforsch. Mikrosk. Anat , vol.135 , pp. 461-471
    • Kalnins, V.I.1    Chung, C.K.2    Turnbull, C.3
  • 16
    • 12144262775 scopus 로고    scopus 로고
    • Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis
    • Spassky, N. et al. Adult ependymal cells are postmitotic and are derived from radial glial cells during embryogenesis. J. Neurosci. 25, 10-18 (2005).
    • (2005) J. Neurosci , vol.25 , pp. 10-18
    • Spassky, N.1
  • 17
    • 34347394349 scopus 로고    scopus 로고
    • Molecular characterization of centriole assembly in ciliated epithelial cells
    • Vladar, E. K. & Stearns, T. Molecular characterization of centriole assembly in ciliated epithelial cells. J. Cell Biol. 178, 31-42 (2007).
    • (2007) J. Cell Biol , vol.178 , pp. 31-42
    • Vladar, E.K.1    Stearns, T.2
  • 18
    • 84885390501 scopus 로고    scopus 로고
    • Deuterosome-mediated centriole biogenesis
    • Klos Dehring, D. A. et al. Deuterosome-mediated centriole biogenesis. Dev. Cell 27, 103-112 (2013).
    • (2013) Dev. Cell , vol.27 , pp. 103-112
    • Klos Dehring, D.A.1
  • 19
    • 84893353424 scopus 로고    scopus 로고
    • The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis
    • Zhao, H. et al. The Cep63 paralogue Deup1 enables massive de novo centriole biogenesis for vertebrate multiciliogenesis. Nat. Cell Biol. 15, 1434-1444 (2013).
    • (2013) Nat. Cell Biol , vol.15 , pp. 1434-1444
    • Zhao, H.1
  • 20
    • 84922332985 scopus 로고    scopus 로고
    • Centriole amplification by mother and daughter centrioles differs in multiciliated cells
    • Al Jord, A. et al. Centriole amplification by mother and daughter centrioles differs in multiciliated cells. Nature 516, 104-107 (2014).
    • (2014) Nature , vol.516 , pp. 104-107
    • Al Jord, A.1
  • 22
    • 0016657783 scopus 로고
    • The cyclical variation in the percentage of ciliated cells in the normal human endometrium
    • Masterton, R., Armstrong, E. M. & More, I. A. The cyclical variation in the percentage of ciliated cells in the normal human endometrium. J. Reprod. Fertil. 42, 537-540 (1974).
    • (1974) J. Reprod. Fertil , vol.42 , pp. 537-540
    • Masterton, R.1    Armstrong, E.M.2    More, I.A.3
  • 23
    • 84949504069 scopus 로고    scopus 로고
    • The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids
    • Kessler, M. et al. The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Nat. Commun. 6, 8989 (2015).
    • (2015) Nat. Commun , vol.6 , pp. 8989
    • Kessler, M.1
  • 24
    • 69149106207 scopus 로고    scopus 로고
    • Basal cells as stem cells of the mouse trachea and human airway epithelium
    • Rock, J. R. et al. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc. Natl Acad. Sci. USA 106, 12771-12775 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 12771-12775
    • Rock, J.R.1
  • 25
    • 2942677539 scopus 로고    scopus 로고
    • Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium
    • Daniely, Y. et al. Critical role of p63 in the development of a normal esophageal and tracheobronchial epithelium. Am. J. Physiol. Cell Physiol. 287, C171-C181 (2004).
    • (2004) Am. J. Physiol. Cell Physiol , vol.287 , pp. C171-C181
    • Daniely, Y.1
  • 26
    • 69549090537 scopus 로고    scopus 로고
    • Multiple roles for Sox2 in the developing and adult mouse trachea
    • Que, J., Luo, X., Schwartz, R. J. & Hogan, B. L. M. Multiple roles for Sox2 in the developing and adult mouse trachea. Development 136, 1899-1907 (2009).
    • (2009) Development , vol.136 , pp. 1899-1907
    • Que, J.1    Luo, X.2    Schwartz, R.J.3    Hogan, B.L.M.4
  • 27
    • 84905869926 scopus 로고    scopus 로고
    • Repair and regeneration of the respiratory system: Complexity, plasticity, and mechanisms of lung stem cell function
    • Hogan, B. L. M. et al. Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function. Cell Stem Cell 15, 123-138 (2014).
    • (2014) Cell Stem Cell , vol.15 , pp. 123-138
    • Hogan, B.L.M.1
  • 28
    • 80054030182 scopus 로고    scopus 로고
    • Epithelial progenitor cells in lung development, maintenance, repair, and disease
    • Rock, J. R. & Hogan, B. L. M. Epithelial progenitor cells in lung development, maintenance, repair, and disease. Annu. Rev. Cell Dev. Biol. 27, 493-512 (2011).
    • (2011) Annu. Rev. Cell Dev. Biol , vol.27 , pp. 493-512
    • Rock, J.R.1    Hogan, B.L.M.2
  • 29
    • 43649102321 scopus 로고    scopus 로고
    • Subventricular zone-mediated ependyma repair in the adult mammalian brain
    • Luo, J., Shook, B. A., Daniels, S. B. & Conover, J. C. Subventricular zone-mediated ependyma repair in the adult mammalian brain. J. Neurosci. 28, 3804-3813 (2008).
    • (2008) J. Neurosci , vol.28 , pp. 3804-3813
    • Luo, J.1    Shook, B.A.2    Daniels, S.B.3    Conover, J.C.4
  • 30
    • 84930227326 scopus 로고    scopus 로고
    • Single-cell transcriptome analyses reveal signals to activate dormant neural stem cells
    • Luo, Y. et al. Single-cell transcriptome analyses reveal signals to activate dormant neural stem cells. Cell 161, 1175-1188 (2015).
    • (2015) Cell , vol.161 , pp. 1175-1188
    • Luo, Y.1
  • 31
    • 84934984011 scopus 로고    scopus 로고
    • Embryonic origin of postnatal neural stem cells
    • Fuentealba, L. C. et al. Embryonic origin of postnatal neural stem cells. Cell 161, 1644-1655 (2015).
    • (2015) Cell , vol.161 , pp. 1644-1655
    • Fuentealba, L.C.1
  • 32
    • 34247391176 scopus 로고    scopus 로고
    • Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros
    • Liu, Y., Pathak, N., Kramer-Zucker, A. & Drummond, I. A. Notch signaling controls the differentiation of transporting epithelia and multiciliated cells in the zebrafish pronephros. Development 134, 1111-1122 (2007).
    • (2007) Development , vol.134 , pp. 1111-1122
    • Liu, Y.1    Pathak, N.2    Kramer-Zucker, A.3    Drummond, I.A.4
  • 33
    • 79957895825 scopus 로고    scopus 로고
    • Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway
    • Marcet, B. et al. Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway. Nat. Cell Biol. 13, 693-699 (2011).
    • (2011) Nat. Cell Biol , vol.13 , pp. 693-699
    • Marcet, B.1
  • 34
    • 73849134811 scopus 로고    scopus 로고
    • Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate
    • Morimoto, M. et al. Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J. Cell Sci. 123, 213-224 (2010).
    • (2010) J. Cell Sci , vol.123 , pp. 213-224
    • Morimoto, M.1
  • 35
    • 84964694187 scopus 로고    scopus 로고
    • Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors
    • Mori, M. et al. Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors. Development 142, 258-267 (2015).
    • (2015) Development , vol.142 , pp. 258-267
    • Mori, M.1
  • 36
    • 84856460296 scopus 로고    scopus 로고
    • Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation
    • Stubbs, J. L., Vladar, E. K., Axelrod, J. D. & Kintner, C. Multicilin promotes centriole assembly and ciliogenesis during multiciliate cell differentiation. Nat. Cell Biol. 14, 140-147 (2012).
    • (2012) Nat. Cell Biol , vol.14 , pp. 140-147
    • Stubbs, J.L.1    Vladar, E.K.2    Axelrod, J.D.3    Kintner, C.4
  • 37
    • 84868537980 scopus 로고    scopus 로고
    • Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells
    • Morimoto, M., Nishinakamura, R., Saga, Y. & Kopan, R. Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells. Development 139, 4365-4373 (2012).
    • (2012) Development , vol.139 , pp. 4365-4373
    • Morimoto, M.1    Nishinakamura, R.2    Saga, Y.3    Kopan, R.4
  • 38
    • 0032730001 scopus 로고    scopus 로고
    • A two-step mechanism generates the spacing pattern of the ciliated cells in the skin of Xenopus embryos
    • Deblandre, G. A., Wettstein, D. A., Koyano-Nakagawa, N. & Kintner, C. A two-step mechanism generates the spacing pattern of the ciliated cells in the skin of Xenopus embryos. Development 126, 4715-4728 (1999).
    • (1999) Development , vol.126 , pp. 4715-4728
    • Deblandre, G.A.1    Wettstein, D.A.2    Koyano-Nakagawa, N.3    Kintner, C.4
  • 39
    • 68549121214 scopus 로고    scopus 로고
    • Notch signaling promotes airway mucous metaplasia and inhibits alveolar development
    • Guseh, J. S. et al. Notch signaling promotes airway mucous metaplasia and inhibits alveolar development. Development 136, 1751-1759 (2009).
    • (2009) Development , vol.136 , pp. 1751-1759
    • Guseh, J.S.1
  • 40
    • 69549088763 scopus 로고    scopus 로고
    • Notch signaling controls the balance of ciliated and secretory cell fates in developing airways
    • Tsao, P.-N. et al. Notch signaling controls the balance of ciliated and secretory cell fates in developing airways. Development 136, 2297-2307 (2009).
    • (2009) Development , vol.136 , pp. 2297-2307
    • Tsao, P.-N.1
  • 41
    • 84923675686 scopus 로고    scopus 로고
    • Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway
    • Gomi, K., Arbelaez, V., Crystal, R. G. & Walters, M. S. Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway. PLoS ONE 10, e0116507 (2015).
    • (2015) PLoS ONE , vol.10 , pp. e0116507
    • Gomi, K.1    Arbelaez, V.2    Crystal, R.G.3    Walters, M.S.4
  • 42
    • 66049083441 scopus 로고    scopus 로고
    • The role of Scgb1a1+ Clara cells in the long-Term maintenance and repair of lung airway, but not alveolar, epithelium
    • Rawlins, E. L. et al. The role of Scgb1a1+ Clara cells in the long-Term maintenance and repair of lung airway, but not alveolar, epithelium. Cell Stem Cell 4, 525-534 (2009).
    • (2009) Cell Stem Cell , vol.4 , pp. 525-534
    • Rawlins, E.L.1
  • 43
    • 84937514411 scopus 로고    scopus 로고
    • Clonal dynamics reveal two distinct populations of basal cells in slow-Turnover airway epithelium
    • Watson, J. K. et al. Clonal dynamics reveal two distinct populations of basal cells in slow-Turnover airway epithelium. Cell Rep. 12, 90-101 (2015).
    • (2015) Cell Rep , vol.12 , pp. 90-101
    • Watson, J.K.1
  • 44
    • 84924867060 scopus 로고    scopus 로고
    • Injury induces direct lineage segregation of functionally distinct airway basal stem/progenitor cell subpopulations
    • Pardo-Saganta, A. et al. Injury induces direct lineage segregation of functionally distinct airway basal stem/progenitor cell subpopulations. Cell Stem Cell 16, 184-197 (2015).
    • (2015) Cell Stem Cell , vol.16 , pp. 184-197
    • Pardo-Saganta, A.1
  • 45
    • 84938381949 scopus 로고    scopus 로고
    • Parent stem cells can serve as niches for their daughter cells
    • Pardo-Saganta, A. et al. Parent stem cells can serve as niches for their daughter cells. Nature 523, 597-601 (2015).
    • (2015) Nature , vol.523 , pp. 597-601
    • Pardo-Saganta, A.1
  • 46
    • 84949224539 scopus 로고    scopus 로고
    • Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung
    • Lafkas, D. et al. Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung. Nature 528, 127-131 (2015).
    • (2015) Nature , vol.528 , pp. 127-131
    • Lafkas, D.1
  • 47
    • 84946606423 scopus 로고    scopus 로고
    • Mcidas and GemC1/Lynkeas are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche
    • Kyrousi, C. et al. Mcidas and GemC1/Lynkeas are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. Development 44, 3661-3674 (2015).
    • (2015) Development , vol.44 , pp. 3661-3674
    • Kyrousi, C.1
  • 48
    • 84936144166 scopus 로고    scopus 로고
    • BMP signalling controls the construction of vertebrate mucociliary epithelia
    • Cibois, M. et al. BMP signalling controls the construction of vertebrate mucociliary epithelia. Development 142, 2352-2363 (2015).
    • (2015) Development , vol.142 , pp. 2352-2363
    • Cibois, M.1
  • 49
    • 84907228030 scopus 로고    scopus 로고
    • IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells
    • Tadokoro, T. et al. IL-6/STAT3 promotes regeneration of airway ciliated cells from basal stem cells. Proc. Natl Acad. Sci. USA 111, E3641-E3699 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. E3641-E3699
    • Tadokoro, T.1
  • 50
    • 33749053844 scopus 로고    scopus 로고
    • Ciliated cells differentiated from mouse embryonic stem cells
    • Nishimura, Y. et al. Ciliated cells differentiated from mouse embryonic stem cells. Stem Cells 24, 1381-1388 (2006).
    • (2006) Stem Cells , vol.24 , pp. 1381-1388
    • Nishimura, Y.1
  • 51
    • 77957662716 scopus 로고    scopus 로고
    • Inhibitory Smad proteins promote the differentiation of mouse embryonic stem cells into ependymal-like ciliated cells
    • Nishimura, Y. et al. Inhibitory Smad proteins promote the differentiation of mouse embryonic stem cells into ependymal-like ciliated cells. Biochem. Biophys. Res. Commun. 401, 1-6 (2010).
    • (2010) Biochem. Biophys. Res. Commun , vol.401 , pp. 1-6
    • Nishimura, Y.1
  • 52
    • 77951976827 scopus 로고    scopus 로고
    • GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication
    • Balestrini, A., Cosentino, C., Errico, A., Garner, E. & Costanzo, V. GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication. Nat. Cell Biol. 12, 484-491 (2010).
    • (2010) Nat. Cell Biol , Issue.12 , pp. 484-491
    • Balestrini, A.1    Cosentino, C.2    Errico, A.3    Garner, E.4    Costanzo, V.5
  • 53
    • 79959562689 scopus 로고    scopus 로고
    • Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression
    • Pefani, D. E. et al. Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression. J. Biol. Chem. 286, 23234-23246 (2011).
    • (2011) J. Biol. Chem , vol.286 , pp. 23234-23246
    • Pefani, D.E.1
  • 54
    • 84887078942 scopus 로고    scopus 로고
    • The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing
    • Caillat, C. et al. The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing. J. Biol. Chem. 288, 31624-31634 (2013).
    • (2013) J. Biol. Chem , vol.288 , pp. 31624-31634
    • Caillat, C.1
  • 55
    • 84903788691 scopus 로고    scopus 로고
    • Multicilin drives centriole biogenesis via E2f proteins
    • Ma, L., Quigley, I., Omran, H. & Kintner, C. Multicilin drives centriole biogenesis via E2f proteins. Genes Dev. 28, 1461-1471 (2014).
    • (2014) Genes Dev , vol.28 , pp. 1461-1471
    • Ma, L.1    Quigley, I.2    Omran, H.3    Kintner, C.4
  • 56
    • 84959270948 scopus 로고    scopus 로고
    • GEMC 1 is a critical regulator of multiciliated cell differentiation
    • Terré, B. et al. GEMC 1 is a critical regulator of multiciliated cell differentiation. EMBO J. 35, 942-960 (2016).
    • (2016) EMBO J , vol.35 , pp. 942-960
    • Terré, B.1
  • 57
    • 84959517060 scopus 로고    scopus 로고
    • GemC1 controls multiciliogenesis in the airway epithelium
    • Arbi, M. et al. GemC1 controls multiciliogenesis in the airway epithelium. EMBO Rep. 17, 400-413 (2016).
    • (2016) EMBO Rep , vol.17 , pp. 400-413
    • Arbi, M.1
  • 58
    • 84906274398 scopus 로고    scopus 로고
    • MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia
    • Boon, M. et al. MCIDAS mutations result in a mucociliary clearance disorder with reduced generation of multiple motile cilia. Nat. Commun. 5, 4418 (2014).
    • (2014) Nat. Commun , vol.5 , pp. 4418
    • Boon, M.1
  • 59
    • 84884930913 scopus 로고    scopus 로고
    • Myb promotes centriole amplification and later steps of the multiciliogenesis program
    • Tan, F. E. et al. Myb promotes centriole amplification and later steps of the multiciliogenesis program. Development 140, 4277-4286 (2013).
    • (2013) Development , vol.140 , pp. 4277-4286
    • Tan, F.E.1
  • 60
    • 84955688268 scopus 로고    scopus 로고
    • Gmnc is a master regulator of the multiciliated cell differentiation program
    • Zhou, F. et al. Gmnc is a master regulator of the multiciliated cell differentiation program. Curr. Biol. 25, 3267-3273 (2015).
    • (2015) Curr. Biol , vol.25 , pp. 3267-3273
    • Zhou, F.1
  • 61
    • 34247634108 scopus 로고    scopus 로고
    • E2f4 is required for normal development of the airway epithelium
    • Danielian, P. S. et al. E2f4 is required for normal development of the airway epithelium. Dev. Biol. 305, 564-576 (2007).
    • (2007) Dev. Biol , vol.305 , pp. 564-576
    • Danielian, P.S.1
  • 62
    • 84962882992 scopus 로고    scopus 로고
    • E2f4 and E2f5 are essential for the development of the male reproductive system
    • Danielian, P. S., Hess, R. A. & Lees, J. A. E2f4 and E2f5 are essential for the development of the male reproductive system. Cell Cycle 15, 250-260 (2016).
    • (2016) Cell Cycle , vol.15 , pp. 250-260
    • Danielian, P.S.1    Hess, R.A.2    Lees, J.A.3
  • 63
    • 84901949738 scopus 로고    scopus 로고
    • MiR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110
    • Song, R. et al. miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110. Nature 510, 115-120 (2014).
    • (2014) Nature , vol.510 , pp. 115-120
    • Song, R.1
  • 64
    • 84904341198 scopus 로고    scopus 로고
    • Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis
    • Wu, J. et al. Two miRNA clusters, miR-34b/c and miR-449, are essential for normal brain development, motile ciliogenesis, and spermatogenesis. Proc. Natl Acad. Sci. USA 111, E2851-E2857 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. E2851-E2857
    • Wu, J.1
  • 66
    • 81755186885 scopus 로고    scopus 로고
    • Six3 is required for ependymal cell maturation
    • Lavado, A. & Oliver, G. Six3 is required for ependymal cell maturation. Development 138, 5291-5300 (2011).
    • (2011) Development , vol.138 , pp. 5291-5300
    • Lavado, A.1    Oliver, G.2
  • 67
    • 79960201140 scopus 로고    scopus 로고
    • Article Ank3-dependent SVZ niche assembly is required for the continued production of new neurons
    • Paez-gonzalez, P. et al. Article Ank3-dependent SVZ niche assembly is required for the continued production of new neurons. Neuron 71, 61-75 (2011).
    • (2011) Neuron , vol.71 , pp. 61-75
    • Paez-Gonzalez, P.1
  • 68
    • 84954432538 scopus 로고    scopus 로고
    • Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus
    • Park, R. et al. Yap is required for ependymal integrity and is suppressed in LPA-induced hydrocephalus. Nat. Commun. 7, 10329 (2016).
    • (2016) Nat. Commun , vol.7 , pp. 10329
    • Park, R.1
  • 69
    • 34250865601 scopus 로고    scopus 로고
    • RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1
    • Pan, J., You, Y., Huang, T. & Brody, S. L. RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1. J. Cell Sci. 120, 1868-1876 (2007).
    • (2007) J. Cell Sci , vol.120 , pp. 1868-1876
    • Pan, J.1    You, Y.2    Huang, T.3    Brody, S.L.4
  • 72
    • 84873409469 scopus 로고    scopus 로고
    • Selective chemical crosslinking reveals a Cep57-Cep63-Cep152 centrosomal complex
    • Lukinavicius, G. et al. Selective chemical crosslinking reveals a Cep57-Cep63-Cep152 centrosomal complex. Curr. Biol. 23, 265-270 (2013).
    • (2013) Curr. Biol , vol.23 , pp. 265-270
    • Lukinavicius, G.1
  • 73
    • 80054978334 scopus 로고    scopus 로고
    • A primary microcephaly protein complex forms a ring around parental centrioles
    • Sir, J.-H. et al. A primary microcephaly protein complex forms a ring around parental centrioles. Nat. Genet. 43, 1147-1153 (2011).
    • (2011) Nat. Genet , vol.43 , pp. 1147-1153
    • Sir, J.-H.1
  • 74
    • 84871801059 scopus 로고    scopus 로고
    • Transcriptional program of ciliated epithelial cells reveals new cilium and centrosome components and links to human disease
    • Hoh, R. A., Stowe, T. R., Turk, E. & Stearns, T. Transcriptional program of ciliated epithelial cells reveals new cilium and centrosome components and links to human disease. PLoS ONE 7, e52166 (2012).
    • (2012) PLoS ONE , vol.7 , pp. e52166
    • Hoh, R.A.1    Stowe, T.R.2    Turk, E.3    Stearns, T.4
  • 75
    • 84878874617 scopus 로고    scopus 로고
    • MiR-34b regulates multiciliogenesis during organ formation in zebrafish
    • Wang, L. et al. miR-34b regulates multiciliogenesis during organ formation in zebrafish. Development 140, 2755-2764 (2013).
    • (2013) Development , vol.140 , pp. 2755-2764
    • Wang, L.1
  • 76
    • 84927688941 scopus 로고    scopus 로고
    • Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells
    • Funk, M. C. et al. Cyclin O (Ccno) functions during deuterosome-mediated centriole amplification of multiciliated cells. EMBO Rep. 34, 1078-1089 (2015).
    • (2015) EMBO Rep , vol.34 , pp. 1078-1089
    • Funk, M.C.1
  • 77
    • 84959345531 scopus 로고    scopus 로고
    • Centriole continuity: Out with the new, in with the old
    • Meunier, A. & Spassky, N. Centriole continuity: out with the new, in with the old. Curr. Opin. Cell Biol. 38, 60-67 (2016).
    • (2016) Curr. Opin. Cell Biol , vol.38 , pp. 60-67
    • Meunier, A.1    Spassky, N.2
  • 78
    • 84976440433 scopus 로고    scopus 로고
    • Computational support for a scaffolding mechanism of centriole assembly
    • Klein, H. C. R., Guichard, P., Hamel, V., Gönczy, P. & Schwarz, U. S. Computational support for a scaffolding mechanism of centriole assembly. Sci. Rep. 6, 27075 (2016).
    • (2016) Sci. Rep , vol.6 , pp. 27075
    • Klein, H.C.R.1    Guichard, P.2    Hamel, V.3    Gönczy, P.4    Schwarz, U.S.5
  • 79
    • 84879880339 scopus 로고    scopus 로고
    • Xenopus laevis nucleotide binding protein 1 (xNubp1) is important for convergent extension movements and controls ciliogenesis via regulation of the actin cytoskeleton
    • Ioannou, A., Santama, N. & Skourides, P. A. Xenopus laevis nucleotide binding protein 1 (xNubp1) is important for convergent extension movements and controls ciliogenesis via regulation of the actin cytoskeleton. Dev. Biol. 380, 243-258 (2013).
    • (2013) Dev. Biol , vol.380 , pp. 243-258
    • Ioannou, A.1    Santama, N.2    Skourides, P.A.3
  • 80
    • 77950498085 scopus 로고    scopus 로고
    • Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia
    • Guirao, B. et al. Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia. Nat. Cell Biol. 12, 341-350 (2010).
    • (2010) Nat. Cell Biol , vol.12 , pp. 341-350
    • Guirao, B.1
  • 81
    • 84901651947 scopus 로고    scopus 로고
    • Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia
    • Wallmeier, J. et al. Mutations in CCNO result in congenital mucociliary clearance disorder with reduced generation of multiple motile cilia. Nat. Genet. 46, 646-651 (2014).
    • (2014) Nat. Genet , vol.46 , pp. 646-651
    • Wallmeier, J.1
  • 82
    • 84960487751 scopus 로고    scopus 로고
    • Systematic analysis of CCNO variants in a defined population: Implications for clinical phenotype and differential diagnosis
    • Amirav, I. et al. Systematic analysis of CCNO variants in a defined population: implications for clinical phenotype and differential diagnosis. Hum. Mutat. 37, 396-405 (2016).
    • (2016) Hum. Mutat , vol.37 , pp. 396-405
    • Amirav, I.1
  • 83
    • 84921344720 scopus 로고    scopus 로고
    • Unexpected genetic heterogeneity for primary ciliary dyskinesia in the Irish Traveller population
    • Casey, J. P. et al. Unexpected genetic heterogeneity for primary ciliary dyskinesia in the Irish Traveller population. Eur. J. Hum. Genet. 23, 210-217 (2015).
    • (2015) Eur. J. Hum. Genet , vol.23 , pp. 210-217
    • Casey, J.P.1
  • 84
    • 0024193261 scopus 로고
    • Development and functions of the cytoskeleton during ciliogenesis in metazoa
    • Lemullois, M., Boisvieux-Ulrich, E., Laine, M. C., Chailley, B. & Sandoz, D. Development and functions of the cytoskeleton during ciliogenesis in metazoa. Biol. Cell 63, 195-208 (1988).
    • (1988) Biol. Cell , vol.63 , pp. 195-208
    • Lemullois, M.1    Boisvieux-Ulrich, E.2    Laine, M.C.3    Chailley, B.4    Sandoz, D.5
  • 85
    • 0025129057 scopus 로고
    • Cytochalasin D inhibits basal body migration and ciliary elongation in quail oviduct epithelium
    • Boisvieux-Ulrich, E., Lainé, M. C. & Sandoz, D. Cytochalasin D inhibits basal body migration and ciliary elongation in quail oviduct epithelium. Cell Tissue Res. 259, 443-454 (1990).
    • (1990) Cell Tissue Res , vol.259 , pp. 443-454
    • Boisvieux-Ulrich, E.1    Lainé, M.C.2    Sandoz, D.3
  • 86
    • 2342417378 scopus 로고    scopus 로고
    • Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells
    • Gomperts, B. N., Gong-Cooper, X. & Hackett, B. P. Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells. J. Cell Sci. 117, 1329-1337 (2004).
    • (2004) J. Cell Sci , vol.117 , pp. 1329-1337
    • Gomperts, B.N.1    Gong-Cooper, X.2    Hackett, B.P.3
  • 87
    • 84941897834 scopus 로고    scopus 로고
    • MiR-34/449 control apical actin network formation during multiciliogenesis through small GTPase pathways
    • Chevalier, B. et al. miR-34/449 control apical actin network formation during multiciliogenesis through small GTPase pathways. Nat. Commun. 6, 8386 (2015).
    • (2015) Nat. Commun , vol.6 , pp. 8386
    • Chevalier, B.1
  • 88
    • 84892381509 scopus 로고    scopus 로고
    • Making the connection: Ciliary adhesion complexes anchor basal bodies to the actin cytoskeleton
    • Antoniades, I., Stylianou, P. & Skourides, P. A. Making the connection: ciliary adhesion complexes anchor basal bodies to the actin cytoskeleton. Dev. Cell 28, 70-80 (2014).
    • (2014) Dev. Cell , vol.28 , pp. 70-80
    • Antoniades, I.1    Stylianou, P.2    Skourides, P.A.3
  • 89
    • 80053946585 scopus 로고    scopus 로고
    • Actin and microtubules drive differential aspects of planar cell polarity in multiciliated cells
    • Werner, M. E. et al. Actin and microtubules drive differential aspects of planar cell polarity in multiciliated cells. J. Cell Biol. 195, 19-26 (2011).
    • (2011) J. Cell Biol , vol.195 , pp. 19-26
    • Werner, M.E.1
  • 90
    • 84926384543 scopus 로고    scopus 로고
    • ERK7 regulates ciliogenesis by phosphorylating the actin regulator CapZIP in cooperation with Dishevelled
    • Miyatake, K., Kusakabe, M., Takahashi, C. & Nishida, E. ERK7 regulates ciliogenesis by phosphorylating the actin regulator CapZIP in cooperation with Dishevelled. Nat. Commun. 6, 6666 (2015).
    • (2015) Nat. Commun , vol.6 , pp. 6666
    • Miyatake, K.1    Kusakabe, M.2    Takahashi, C.3    Nishida, E.4
  • 91
    • 33644624937 scopus 로고    scopus 로고
    • Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling
    • Park, T. J., Haigo, S. L. & Wallingford, J. B. Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling. Nat. Genet. 38, 303-311 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 303-311
    • Park, T.J.1    Haigo, S.L.2    Wallingford, J.B.3
  • 92
    • 46249125254 scopus 로고    scopus 로고
    • Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells
    • Park, T. J., Mitchell, B. J., Abitua, P. B., Kintner, C. & Wallingford, J. B. Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Nat. Genet. 40, 871-879 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 871-879
    • Park, T.J.1    Mitchell, B.J.2    Abitua, P.B.3    Kintner, C.4    Wallingford, J.B.5
  • 93
    • 84980406151 scopus 로고    scopus 로고
    • Flattop regulates basal body docking and positioning in mono-And multiciliated cells
    • Gegg, M. et al. Flattop regulates basal body docking and positioning in mono-And multiciliated cells. eLife 3, e03842 (2014).
    • (2014) ELife , vol.3 , pp. e03842
    • Gegg, M.1
  • 94
    • 70349651962 scopus 로고    scopus 로고
    • The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis, and mouse embryonic development
    • Gray, R. S. et al. The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis, and mouse embryonic development. Nat. Cell Biol. 11, 1225-1232 (2009).
    • (2009) Nat. Cell Biol , vol.11 , pp. 1225-1232
    • Gray, R.S.1
  • 95
    • 84959372216 scopus 로고    scopus 로고
    • The polarity protein inturned links NPHP4 to daam1 to control the subapical actin network in multiciliated cells
    • Yasunaga, T. et al. The polarity protein inturned links NPHP4 to daam1 to control the subapical actin network in multiciliated cells. J. Cell Biol. 211, 963-973 (2015).
    • (2015) J. Cell Biol , vol.211 , pp. 963-973
    • Yasunaga, T.1
  • 96
    • 77952850722 scopus 로고    scopus 로고
    • Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus
    • Tissir, F. et al. Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus. Nat. Neurosci. 13, 700-707 (2010).
    • (2010) Nat. Neurosci , vol.13 , pp. 700-707
    • Tissir, F.1
  • 97
    • 84904994416 scopus 로고    scopus 로고
    • A dual role for planar cell polarity genes in ciliated cells
    • Boutin, C. et al. A dual role for planar cell polarity genes in ciliated cells. Proc. Natl Acad. Sci. USA 111, E3129-E3138 (2014).
    • (2014) Proc. Natl Acad. Sci. USA , vol.111 , pp. E3129-E3138
    • Boutin, C.1
  • 98
    • 67349154436 scopus 로고    scopus 로고
    • The PCP pathway instructs the planar orientation of ciliated cells in the Xenopus larval skin
    • Mitchell, B. et al. The PCP pathway instructs the planar orientation of ciliated cells in the Xenopus larval skin. Curr. Biol. 19, 924-929 (2009).
    • (2009) Curr. Biol , vol.19 , pp. 924-929
    • Mitchell, B.1
  • 99
    • 0024495844 scopus 로고
    • In vitro effects of taxol on ciliogenesis in quail oviduct
    • Boisvieux-Ulrich, E., Laine, M. C. & Sandoz, D. In vitro effects of taxol on ciliogenesis in quail oviduct. J. Cell Sci. 92, 9-20 (1989).
    • (1989) J. Cell Sci , vol.92 , pp. 9-20
    • Boisvieux-Ulrich, E.1    Laine, M.C.2    Sandoz, D.3
  • 100
    • 84938683916 scopus 로고    scopus 로고
    • The essential roles of transition fibers in the context of cilia
    • Wei, Q., Ling, K. & Hu, J. The essential roles of transition fibers in the context of cilia. Curr. Opin. Cell Biol. 35, 98-105 (2015).
    • (2015) Curr. Opin. Cell Biol , vol.35 , pp. 98-105
    • Wei, Q.1    Ling, K.2    Hu, J.3
  • 101
    • 84908373996 scopus 로고    scopus 로고
    • Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation
    • Burke, M. C. et al. Chibby promotes ciliary vesicle formation and basal body docking during airway cell differentiation. J. Cell Biol. 207, 123-137 (2014).
    • (2014) J. Cell Biol , vol.207 , pp. 123-137
    • Burke, M.C.1
  • 102
    • 70350362831 scopus 로고    scopus 로고
    • RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies
    • El Zein, L. et al. RFX3 governs growth and beating efficiency of motile cilia in mouse and controls the expression of genes involved in human ciliopathies. J. Cell Sci. 122, 3180-3189 (2009).
    • (2009) J. Cell Sci , vol.122 , pp. 3180-3189
    • El Zein, L.1
  • 103
    • 84857033077 scopus 로고    scopus 로고
    • RFX2 is broadly required for ciliogenesis during vertebrate development
    • Chung, M. I. et al. RFX2 is broadly required for ciliogenesis during vertebrate development. Dev. Biol. 363, 155-165 (2012).
    • (2012) Dev. Biol , vol.363 , pp. 155-165
    • Chung, M.I.1
  • 104
    • 84892568851 scopus 로고    scopus 로고
    • Coordinated genomic control of ciliogenesis and cell movement by RFX2
    • Chung, M. I. et al. Coordinated genomic control of ciliogenesis and cell movement by RFX2. eLife 3, e01439 (2014).
    • (2014) ELife , vol.3 , pp. e01439
    • Chung, M.I.1
  • 105
    • 84896257145 scopus 로고    scopus 로고
    • Switching on cilia: Transcriptional networks regulating ciliogenesis
    • Choksi, S. P., Lauter, G., Swoboda, P. & Roy, S. Switching on cilia: Transcriptional networks regulating ciliogenesis. Development 141, 1427-1441 (2014).
    • (2014) Development , vol.141 , pp. 1427-1441
    • Choksi, S.P.1    Lauter, G.2    Swoboda, P.3    Roy, S.4
  • 106
    • 0032530312 scopus 로고    scopus 로고
    • Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia andrandom left-right asymmetry
    • Chen, J., Knowles, H. J., Hebert, J. L. & Hackett, B. P. Mutation of the mouse hepatocyte nuclear factor/forkhead homologue 4 gene results in an absence of cilia and random left-right asymmetry. J. Clin. Invest. 102, 1077-1082 (1998).
    • (1998) J. Clin. Invest , vol.102 , pp. 1077-1082
    • Chen, J.1    Knowles, H.J.2    Hebert, J.L.3    Hackett, B.P.4
  • 107
    • 0033901391 scopus 로고    scopus 로고
    • Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null mice (aka FOXJ1 mutant mice
    • Brody, S. L., Yan, X. H., Wuerffel, M. K., Song, S. & Shapiro, S. D. Ciliogenesis and left-right axis defects in forkhead factor HFH-4-null mice (aka FOXJ1 mutant mice). Am. J. Respir. Cell Mol. Biol. 23, 45-51 (2000).
    • (2000) Am. J. Respir. Cell Mol. Biol , vol.23 , pp. 45-51
    • Brody, S.L.1    Yan, X.H.2    Wuerffel, M.K.3    Song, S.4    Shapiro, S.D.5
  • 108
    • 56749163207 scopus 로고    scopus 로고
    • Foxj1 transcription factors are master regulators of the motile ciliogenic program
    • Yu, X., Ng, C. P., Habacher, H. & Roy, S. Foxj1 transcription factors are master regulators of the motile ciliogenic program. Nat. Genet. 40, 1445-1453 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 1445-1453
    • Yu, X.1    Ng, C.P.2    Habacher, H.3    Roy, S.4
  • 109
    • 84879831717 scopus 로고    scopus 로고
    • RFX3 modulation of FOXJ1 regulation of cilia genes in the human epithelium
    • Didon, L. et al. RFX3 modulation of FOXJ1 regulation of cilia genes in the human epithelium. Respir. Res. 14, 70 (2013).
    • (2013) Respir. Res , vol.14 , pp. 70
    • Didon, L.1
  • 110
    • 84929701978 scopus 로고    scopus 로고
    • TGF-β signaling regulates the differentiation of motile cilia
    • Tözser, J. et al. TGF-β signaling regulates the differentiation of motile cilia. Cell Rep. 11, 1000-1007 (2015).
    • (2015) Cell Rep , vol.11 , pp. 1000-1007
    • Tözser, J.1
  • 111
    • 84951133522 scopus 로고    scopus 로고
    • IFT-cargo interactions and protein transport in cilia
    • Lechtreck, K. F. IFT-cargo interactions and protein transport in cilia. Trends Biochem. Sci. 40, 765-778 (2015).
    • (2015) Trends Biochem. Sci , vol.40 , pp. 765-778
    • Lechtreck, K.F.1
  • 112
    • 84974593589 scopus 로고    scopus 로고
    • TAp73 is a central transcriptional regulator of airway multiciliogenesis
    • Nemajerova, A. et al. TAp73 is a central transcriptional regulator of airway multiciliogenesis. Genes Dev. 30, 1300-1312 (2016).
    • (2016) Genes Dev , vol.30 , pp. 1300-1312
    • Nemajerova, A.1
  • 113
    • 84960431874 scopus 로고    scopus 로고
    • P73 is required for multiciliogenesis and regulates the Foxj1-Associated gene network
    • Marshall, C. B. et al. P73 is required for multiciliogenesis and regulates the Foxj1-Associated gene network. Cell Rep. 14, 2289-2300 (2016).
    • (2016) Cell Rep , vol.14 , pp. 2289-2300
    • Marshall, C.B.1
  • 114
    • 84973662056 scopus 로고    scopus 로고
    • P73 is required for ependymal cell maturation and neurogenic SVZ cytoarchitecture Abbreviated
    • Gonzalez-Cano, L. et al. p73 is required for ependymal cell maturation and neurogenic SVZ cytoarchitecture Abbreviated. Dev. Neurobiol. 76, 730-747 (2015).
    • (2015) Dev. Neurobiol , vol.76 , pp. 730-747
    • Gonzalez-Cano, L.1
  • 115
    • 84879155737 scopus 로고    scopus 로고
    • Planar cell polarity signaling: Coordination of cellular orientation across tissues
    • Singh, J. & Mlodzik, M. Planar cell polarity signaling: coordination of cellular orientation across tissues. Wiley Interdiscip. Rev. Dev. Biol. 1, 479-499 (2012).
    • (2012) Wiley Interdiscip. Rev. Dev. Biol , vol.1 , pp. 479-499
    • Singh, J.1    Mlodzik, M.2
  • 116
  • 117
    • 84905579089 scopus 로고    scopus 로고
    • Loss of dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus
    • Ohata, S. et al. Loss of dishevelleds disrupts planar polarity in ependymal motile cilia and results in hydrocephalus. Neuron 83, 558-571 (2014).
    • (2014) Neuron , vol.83 , pp. 558-571
    • Ohata, S.1
  • 118
    • 84975488373 scopus 로고    scopus 로고
    • Dynamics of planar cell polarity protein Vangl2 in the mouse oviduct epithelium
    • Shi, D. et al. Dynamics of planar cell polarity protein Vangl2 in the mouse oviduct epithelium. Mech. Dev. 141, 78-89 (2016).
    • (2016) Mech. Dev , vol.141 , pp. 78-89
    • Shi, D.1
  • 119
    • 34249664330 scopus 로고    scopus 로고
    • Wnt5a functions in planar cell polarity regulation in mice
    • Qian, D. et al. Wnt5a functions in planar cell polarity regulation in mice. Dev. Biol. 306, 121-133 (2007).
    • (2007) Dev. Biol , vol.306 , pp. 121-133
    • Qian, D.1
  • 120
    • 59049094574 scopus 로고    scopus 로고
    • WNT11 acts as a directional cue to organize the elongation of early muscle fibres
    • Gros, J., Serralbo, O. & Marcelle, C. WNT11 acts as a directional cue to organize the elongation of early muscle fibres. Nature 457, 589-593 (2009).
    • (2009) Nature , vol.457 , pp. 589-593
    • Gros, J.1    Serralbo, O.2    Marcelle, C.3
  • 121
    • 79751515852 scopus 로고    scopus 로고
    • Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2
    • Gao, B. et al. Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2. Dev. Cell 20, 163-176 (2011).
    • (2011) Dev. Cell , vol.20 , pp. 163-176
    • Gao, B.1
  • 122
    • 84938800652 scopus 로고    scopus 로고
    • Mechanosensory genes Pkd1 and Pkd2 contribute to the planar polarization of brain ventricular epithelium
    • Ohata, S. et al. Mechanosensory genes Pkd1 and Pkd2 contribute to the planar polarization of brain ventricular epithelium. J. Neurosci. 35, 11153-11168 (2015).
    • (2015) J. Neurosci , vol.35 , pp. 11153-11168
    • Ohata, S.1
  • 123
    • 84960808725 scopus 로고    scopus 로고
    • Mechanical strain determines the axis of planar polarity in ciliated epithelia
    • Chien, Y. H., Keller, R., Kintner, C. & Shook, D. R. Mechanical strain determines the axis of planar polarity in ciliated epithelia. Curr. Biol. 25, 2774-2784 (2015).
    • (2015) Curr. Biol , vol.25 , pp. 2774-2784
    • Chien, Y.H.1    Keller, R.2    Kintner, C.3    Shook, D.R.4
  • 124
    • 34247555530 scopus 로고    scopus 로고
    • A positive feedback mechanism governs the polarity and motion of motile cilia
    • Mitchell, B., Jacobs, R., Li, J., Chien, S. & Kintner, C. A positive feedback mechanism governs the polarity and motion of motile cilia. Nature 447, 97-101 (2007).
    • (2007) Nature , vol.447 , pp. 97-101
    • Mitchell, B.1    Jacobs, R.2    Li, J.3    Chien, S.4    Kintner, C.5
  • 125
    • 84880947512 scopus 로고    scopus 로고
    • Bbof1 is required to maintain cilia orientation
    • Chien, Y.-H. et al. Bbof1 is required to maintain cilia orientation. Development 140, 3468-3477 (2013).
    • (2013) Development , vol.140 , pp. 3468-3477
    • Chien, Y.-H.1
  • 127
    • 84878631386 scopus 로고    scopus 로고
    • The establishment of rotational polarity in the airway and ependymal cilia: Analysis with a novel cilium motility mutant mouse
    • Matsuo, M., Shimada, A., Koshida, S., Saga, Y. & Takeda, H. The establishment of rotational polarity in the airway and ependymal cilia: Analysis with a novel cilium motility mutant mouse. Am. J. Physiol. Lung Cell. Mol. Physiol. 304, L736-L745 (2013).
    • (2013) Am. J. Physiol. Lung Cell. Mol. Physiol , vol.304 , pp. L736-L745
    • Matsuo, M.1    Shimada, A.2    Koshida, S.3    Saga, Y.4    Takeda, H.5
  • 128
    • 0024250015 scopus 로고
    • Organization and functions of cytoskeleton in metazoan ciliated cells
    • Sandoz, D. et al. Organization and functions of cytoskeleton in metazoan ciliated cells. Biol. Cell 63, 183-193 (1988).
    • (1988) Biol. Cell , vol.63 , pp. 183-193
    • Sandoz, D.1
  • 129
    • 0034489328 scopus 로고    scopus 로고
    • Localization of gamma-Tubulin to the basal foot associated with the basal body extending a cilium
    • Hagiwara, H., Kano, A., Aoki, T., Ohwada, N. & Takata, K. Localization of gamma-Tubulin to the basal foot associated with the basal body extending a cilium. Histochem. J. 32, 669-671 (2000).
    • (2000) Histochem. J , vol.32 , pp. 669-671
    • Hagiwara, H.1    Kano, A.2    Aoki, T.3    Ohwada, N.4    Takata, K.5
  • 130
    • 84856093088 scopus 로고    scopus 로고
    • Coordinated ciliary beating requires Odf2-mediated polarization of basal bodies via basal feet
    • Kunimoto, K. et al. Coordinated ciliary beating requires Odf2-mediated polarization of basal bodies via basal feet. Cell 148, 189-200 (2012).
    • (2012) Cell , vol.148 , pp. 189-200
    • Kunimoto, K.1
  • 131
    • 84990848509 scopus 로고    scopus 로고
    • Multiciliated cell basal bodies align in stereotypical patterns coordinated by the apical cytoskeleton
    • Herawati, E. et al. Multiciliated cell basal bodies align in stereotypical patterns coordinated by the apical cytoskeleton. J. Cell Biol. 214, 571-586 (2016).
    • (2016) J. Cell Biol , vol.214 , pp. 571-586
    • Herawati, E.1
  • 132
    • 84939573869 scopus 로고    scopus 로고
    • Basal foot MTOC organizes pillar MTs required for coordination of beating cilia
    • Clare, D. K. et al. Basal foot MTOC organizes pillar MTs required for coordination of beating cilia. Nat. Commun. 5, 4888 (2014).
    • (2014) Nat. Commun , vol.5 , pp. 4888
    • Clare, D.K.1
  • 133
    • 84899639463 scopus 로고    scopus 로고
    • Centrin 2 is required for mouse olfactory ciliary trafficking and development of ependymal cilia planar polarity
    • Ying, G. et al. Centrin 2 is required for mouse olfactory ciliary trafficking and development of ependymal cilia planar polarity. J. Neurosci. 34, 6377-6388 (2014).
    • (2014) J. Neurosci , vol.34 , pp. 6377-6388
    • Ying, G.1
  • 134
    • 84908179373 scopus 로고    scopus 로고
    • Sperm-Associated antigen 6 (SPAG6) deficiency and defects in ciliogenesis and cilia function: Polarity, density, and beat
    • Teves, M. E. et al. Sperm-Associated antigen 6 (SPAG6) deficiency and defects in ciliogenesis and cilia function: polarity, density, and beat. PLoS ONE 9, e107271 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e107271
    • Teves, M.E.1
  • 135
    • 84954392734 scopus 로고    scopus 로고
    • Myosin Id is required for planar cell polarity in ciliated tracheal and ependymal epithelial cells
    • Hegan, P. S., Ostertag, E., Geurts, A. M. & Mooseker, M. S. Myosin Id is required for planar cell polarity in ciliated tracheal and ependymal epithelial cells. Cytoskeleton (Hoboken) 72, 503-516 (2015).
    • (2015) Cytoskeleton (Hoboken) , vol.72 , pp. 503-516
    • Hegan, P.S.1    Ostertag, E.2    Geurts, A.M.3    Mooseker, M.S.4
  • 136
    • 77956572483 scopus 로고    scopus 로고
    • Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II
    • Hirota, Y. et al. Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II. Development 137, 3037-3046 (2010).
    • (2010) Development , vol.137 , pp. 3037-3046
    • Hirota, Y.1
  • 137
    • 33947699960 scopus 로고    scopus 로고
    • Spontaneous creation of macroscopic flow and metachronal waves in an array of cilia
    • Guirao, B. & Joanny, J.-F. Spontaneous creation of macroscopic flow and metachronal waves in an array of cilia. Biophys. J. 92, 1900-1917 (2007).
    • (2007) Biophys. J , vol.92 , pp. 1900-1917
    • Guirao, B.1    Joanny, J.-F.2
  • 138
    • 84875263624 scopus 로고    scopus 로고
    • Emergence of metachronal waves in cilia arrays
    • Elgeti, J. & Gompper, G. Emergence of metachronal waves in cilia arrays. Proc. Natl Acad. Sci. USA 110, 4470-4475 (2013).
    • (2013) Proc. Natl Acad. Sci. USA , vol.110 , pp. 4470-4475
    • Elgeti, J.1    Gompper, G.2
  • 139
    • 84918511504 scopus 로고    scopus 로고
    • The effect of drugs and other compounds on the ciliary beat frequency of human respiratory epithelium
    • Workman, A. D. & Cohen, N. A. The effect of drugs and other compounds on the ciliary beat frequency of human respiratory epithelium. Am. J. Rhinol. Allergy 28, 454-464 (2014).
    • (2014) Am. J. Rhinol. Allergy , vol.28 , pp. 454-464
    • Workman, A.D.1    Cohen, N.A.2
  • 140
  • 141
    • 15544377977 scopus 로고    scopus 로고
    • TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity
    • Andrade, Y. N. et al. TRPV4 channel is involved in the coupling of fluid viscosity changes to epithelial ciliary activity. J. Cell Biol. 168, 869-874 (2005).
    • (2005) J. Cell Biol , vol.168 , pp. 869-874
    • Andrade, Y.N.1
  • 142
    • 84881051634 scopus 로고    scopus 로고
    • Structure and function of the mucus clearance system of the lung
    • Button, B. M. & Button, B. Structure and function of the mucus clearance system of the lung. Cold Spring Harb. Perspect. Med. 3, a009720 (2013).
    • (2013) Cold Spring Harb. Perspect. Med , vol.3 , pp. a009720
    • Button, B.M.1    Button, B.2
  • 143
    • 44649101344 scopus 로고    scopus 로고
    • The effect of viscous loading on brain ependymal cilia
    • OCallaghan, C. L., Sikand, K., Rutman, A. & Hirst, R. A. The effect of viscous loading on brain ependymal cilia. Neurosci. Lett. 439, 56-60 (2008).
    • (2008) Neurosci. Lett , vol.439 , pp. 56-60
    • Ocallaghan, C.L.1    Sikand, K.2    Rutman, A.3    Hirst, R.A.4
  • 144
    • 70349612312 scopus 로고    scopus 로고
    • A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus
    • Wodarczyk, C. et al. A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus. PLoS ONE 4, e7137 (2009).
    • (2009) PLoS ONE , vol.4 , pp. e7137
    • Wodarczyk, C.1
  • 145
    • 84869427633 scopus 로고    scopus 로고
    • Sensory functions of motile cilia and implication for bronchiectasis
    • Jain, R. et al. Sensory functions of motile cilia and implication for bronchiectasis. Front. Biosci. (Schol. Ed.) 4, 1088-1098 (2012).
    • (2012) Front. Biosci. (Schol. Ed.) , vol.4 , pp. 1088-1098
    • Jain, R.1
  • 146
    • 84857734855 scopus 로고    scopus 로고
    • Acquired cilia dysfunction in chronic rhinosinusitis
    • Gudis, D., Zhao, K. Q. & Cohen, N. A. Acquired cilia dysfunction in chronic rhinosinusitis. Am. J. Rhinol. Allergy 26, 1-6 (2012).
    • (2012) Am. J. Rhinol. Allergy , vol.26 , pp. 1-6
    • Gudis, D.1    Zhao, K.Q.2    Cohen, N.A.3
  • 147
    • 0035667908 scopus 로고    scopus 로고
    • IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cells
    • Laoukili, J. et al. IL-13 alters mucociliary differentiation and ciliary beating of human respiratory epithelial cells. J. Clin. Invest. 108, 1817-1824 (2001).
    • (2001) J. Clin. Invest , vol.108 , pp. 1817-1824
    • Laoukili, J.1
  • 148
    • 47849088685 scopus 로고    scopus 로고
    • The effect of interleukin-6 on ciliary beat frequency in the human fallopian tube
    • Papathanasiou, A., Djahanbakhch, O., Saridogan, E. & Lyons, R. A. The effect of interleukin-6 on ciliary beat frequency in the human fallopian tube. Fertil. Steril. 90, 391-394 (2008).
    • (2008) Fertil. Steril , vol.90 , pp. 391-394
    • Papathanasiou, A.1    Djahanbakhch, O.2    Saridogan, E.3    Lyons, R.A.4
  • 149
    • 77952108293 scopus 로고    scopus 로고
    • Rapid effects of progesterone on ciliary beat frequency in the mouse fallopian tube
    • Bylander, A. et al. Rapid effects of progesterone on ciliary beat frequency in the mouse fallopian tube. Reprod. Biol. Endocrinol. 8, 48 (2010).
    • (2010) Reprod. Biol. Endocrinol , vol.8 , pp. 48
    • Bylander, A.1
  • 150
    • 0035865388 scopus 로고    scopus 로고
    • Intracellular pathways regulating ciliary beating of rat brain ependymal cells
    • Nguyen, T., Chin, W. C., OBrien, J. A., Verdugo, P. & Berger, A. J. Intracellular pathways regulating ciliary beating of rat brain ependymal cells. J. Physiol. 531, 131-140 (2001).
    • (2001) J. Physiol , vol.531 , pp. 131-140
    • Nguyen, T.1    Chin, W.C.2    Obrien, J.A.3    Verdugo, P.4    Berger, A.J.5
  • 151
    • 84891689207 scopus 로고    scopus 로고
    • Melanin-concentrating hormone regulates beat frequency of ependymal cilia and ventricular volume
    • Conductier, G. et al. Melanin-concentrating hormone regulates beat frequency of ependymal cilia and ventricular volume. Nat. Neurosci. 16, 845-847 (2013).
    • (2013) Nat. Neurosci , vol.16 , pp. 845-847
    • Conductier, G.1
  • 152
    • 78649735324 scopus 로고    scopus 로고
    • Airway mucus function and dysfunction
    • Fahy, J. V. & Dickey, B. F. Airway mucus function and dysfunction. N. Engl. J. Med. 363, 2233-2247 (2010).
    • (2010) N. Engl. J. Med , vol.363 , pp. 2233-2247
    • Fahy, J.V.1    Dickey, B.F.2
  • 153
    • 0036198121 scopus 로고    scopus 로고
    • Antimicrobial polypeptides in host defense of the respiratory tract
    • Ganz, T. Antimicrobial polypeptides in host defense of the respiratory tract. J. Clin. Invest. 109, 693-697 (2002).
    • (2002) J. Clin. Invest , vol.109 , pp. 693-697
    • Ganz, T.1
  • 154
    • 0036194724 scopus 로고    scopus 로고
    • Mucus clearance as a primary innate defense mechanism for mammalian airways
    • Knowles, M. R. & Boucher, R. C. Mucus clearance as a primary innate defense mechanism for mammalian airways. J. Clin. Invest. 109, 571-577 (2002).
    • (2002) J. Clin. Invest , vol.109 , pp. 571-577
    • Knowles, M.R.1    Boucher, R.C.2
  • 155
    • 77049131099 scopus 로고
    • Further observations of nasal cilia
    • Tremble, E. Further observations of nasal cilia. Laryngoscope 63, 619-631 (1953).
    • (1953) Laryngoscope , vol.63 , pp. 619-631
    • Tremble, E.1
  • 158
    • 0035940305 scopus 로고    scopus 로고
    • The nose and paranasal sinuses
    • Jones, N. The nose and paranasal sinuses. Adv. Drug Deliv. Rev. 51, 5-19 (2001).
    • (2001) Adv. Drug Deliv. Rev , vol.51 , pp. 5-19
    • Jones, N.1
  • 159
    • 0025289612 scopus 로고
    • Morphology of the human olfactory epithelium
    • Morrison, E. & Costanzo, R. Morphology of the human olfactory epithelium. J. Comp. Neurol. 297, 1-13 (1990).
    • (1990) J. Comp. Neurol , vol.297 , pp. 1-13
    • Morrison, E.1    Costanzo, R.2
  • 160
    • 84907120457 scopus 로고
    • Ultrastructure of the middle ear mucosa
    • Hentzer, E. Ultrastructure of the middle ear mucosa. Acta Otolaryngol. Suppl. 414, 19-27 (1984).
    • (1984) Acta Otolaryngol. Suppl , vol.414 , pp. 19-27
    • Hentzer, E.1
  • 161
    • 0021734860 scopus 로고
    • Functional morphology of the tubotympanum. An overview
    • Lim, D. J. Functional morphology of the tubotympanum. An overview. Acta Otolaryngol. Suppl. 414, 13-18 (1984).
    • (1984) Acta Otolaryngol. Suppl , vol.414 , pp. 13-18
    • Lim, D.J.1
  • 162
    • 0014117270 scopus 로고
    • Ciliary activity and middle ear clearance
    • Sade, J. Ciliary activity and middle ear clearance. Arch. Otolaryngol. 86, 128-135 (1967).
    • (1967) Arch. Otolaryngol , vol.86 , pp. 128-135
    • Sade, J.1
  • 163
    • 84911945917 scopus 로고    scopus 로고
    • Otitis media in sperm-Associated antigen 6 (Spag6)-deficient mice
    • Li, X. et al. Otitis media in sperm-Associated antigen 6 (Spag6)-deficient mice. PLoS ONE 9, 2-9 (2014).
    • (2014) PLoS ONE , vol.9 , pp. 2-9
    • Li, X.1
  • 165
    • 84865305392 scopus 로고    scopus 로고
    • A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia
    • Button, B. et al. A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia. Science 337, 937-941 (2012).
    • (2012) Science , vol.337 , pp. 937-941
    • Button, B.1
  • 166
    • 84879974863 scopus 로고    scopus 로고
    • Mechanosensitive ATP release maintains proper mucus hydration of airways
    • Button, B., Okada, S. F., Frederick, C. B., Thelin, W. R. & Boucher, R. C. Mechanosensitive ATP release maintains proper mucus hydration of airways. Sci. Signal. 6, ra46 (2013).
    • (2013) Sci. Signal , vol.6 , pp. ra46
    • Button, B.1    Okada, S.F.2    Frederick, C.B.3    Thelin, W.R.4    Boucher, R.C.5
  • 167
    • 85009357341 scopus 로고    scopus 로고
    • Motile-cilia-mediated flow improves sensitivity and temporal resolution of olfactory computations
    • Reiten, I. et al. Motile-cilia-mediated flow improves sensitivity and temporal resolution of olfactory computations. Curr. Biol. 27, 166-174 (2016).
    • (2016) Curr. Biol , vol.27 , pp. 166-174
    • Reiten, I.1
  • 168
    • 0016743258 scopus 로고
    • Human endometrial fluid kinetics as observed by scanning electron microscopy
    • Hafez, E. S., Ludwig, H. & Metzger, H. Human endometrial fluid kinetics as observed by scanning electron microscopy. Am. J. Obstet. Gynecol. 122, 929-938 (1975).
    • (1975) Am. J. Obstet. Gynecol , vol.122 , pp. 929-938
    • Hafez, E.S.1    Ludwig, H.2    Metzger, H.3
  • 169
    • 0028575665 scopus 로고
    • A comparative morphological and ultrastructural study of endometrial gland and fallopian tube epithelia at different stages of the menstrual cycle and the menopause
    • Amso, N. N., Crow, J., Lewin, J. & Shaw, R. W. A comparative morphological and ultrastructural study of endometrial gland and fallopian tube epithelia at different stages of the menstrual cycle and the menopause. Hum. Reprod. 9, 2234-2241 (1994).
    • (1994) Hum. Reprod , vol.9 , pp. 2234-2241
    • Amso, N.N.1    Crow, J.2    Lewin, J.3    Shaw, R.W.4
  • 170
    • 0017122078 scopus 로고
    • The re-epithelization of endometrium after menstrual desquamation
    • Ludwig, H. & Metzger, H. The re-epithelization of endometrium after menstrual desquamation. Arch. Gynakol. 221, 51-60 (1976).
    • (1976) Arch. Gynakol , vol.221 , pp. 51-60
    • Ludwig, H.1    Metzger, H.2
  • 171
    • 0021883090 scopus 로고
    • Cyclic changes in ciliation, cell height, and mitotic activity in human tubal epithelium during reproductive life
    • Donnez, J., Casanas-Roux, F., Caprasse, J., Ferin, J. & Thomas, K. Cyclic changes in ciliation, cell height, and mitotic activity in human tubal epithelium during reproductive life. Fertil. Steril. 43, 554-559 (1985).
    • (1985) Fertil. Steril , vol.43 , pp. 554-559
    • Donnez, J.1    Casanas-Roux, F.2    Caprasse, J.3    Ferin, J.4    Thomas, K.5
  • 172
    • 0028605956 scopus 로고
    • Morphology and infrastructure of Fallopian tube epithelium at different stages of the menstrual cycle and menopause
    • Crow, J., Amso, N. N., Lewin, J. & Shaw, R. W. Morphology and infrastructure of Fallopian tube epithelium at different stages of the menstrual cycle and menopause. Hum. Reprod. 9, 2224-2233 (1994).
    • (1994) Hum. Reprod , vol.9 , pp. 2224-2233
    • Crow, J.1    Amso, N.N.2    Lewin, J.3    Shaw, R.W.4
  • 173
    • 0015375839 scopus 로고
    • Scanning electron microscopic study of the human fallopian tube. Report, I. The proliferative and secretory stages
    • Patek, E., Nilsson, L. & Johannisson, E. Scanning electron microscopic study of the human fallopian tube. Report, I. The proliferative and secretory stages. Fertil. Steril. 23, 549-565 (1972).
    • (1972) Fertil. Steril , vol.23 , pp. 549-565
    • Patek, E.1    Nilsson, L.2    Johannisson, E.3
  • 175
  • 176
    • 0017262950 scopus 로고
    • Egg transport in the rabbit oviduct: The roles of cilia and muscle
    • Halbert, S. A., Tam, P. Y. & Blandau, R. J. Egg transport in the rabbit oviduct: The roles of cilia and muscle. Science 191, 1052-1053 (1976).
    • (1976) Science , vol.191 , pp. 1052-1053
    • Halbert, S.A.1    Tam, P.Y.2    Blandau, R.J.3
  • 177
    • 0019278390 scopus 로고
    • Evidence that adhesive sites on the tips of oviduct cilia membranes are required for ovum pickup
    • Norwood, J. T. & Anderson, R. G. Evidence that adhesive sites on the tips of oviduct cilia membranes are required for ovum pickup in situ. Biol. Reprod. 23, 788-791 (1980).
    • (1980) Situ. Biol. Reprod , vol.23 , pp. 788-791
    • Norwood, J.T.1    Anderson, R.G.2
  • 178
    • 0015446990 scopus 로고
    • Ciliary activity in the mouse oviduct as studied by transmission and scanning electron microscopy
    • Dirksen, E. R. & Satir, P. Ciliary activity in the mouse oviduct as studied by transmission and scanning electron microscopy. Tissue Cell 4, 389-404 (1972).
    • (1972) Tissue Cell , vol.4 , pp. 389-404
    • Dirksen, E.R.1    Satir, P.2
  • 179
    • 0036119730 scopus 로고    scopus 로고
    • Fallopian tube ciliary beat frequency in relation to the stage of menstrual cycle and anatomical site
    • Lyons, R. A. et al. Fallopian tube ciliary beat frequency in relation to the stage of menstrual cycle and anatomical site. Hum. Reprod. 17, 584-588 (2002).
    • (2002) Hum. Reprod , vol.17 , pp. 584-588
    • Lyons, R.A.1
  • 180
    • 29144528913 scopus 로고    scopus 로고
    • The effect of ovarian follicular fluid and peritoneal fluid on Fallopian tube ciliary beat frequency
    • Lyons, R. A., Saridogan, E. & Djahanbakhch, O. The effect of ovarian follicular fluid and peritoneal fluid on Fallopian tube ciliary beat frequency. Hum. Reprod. 21, 52-56 (2006).
    • (2006) Hum. Reprod , vol.21 , pp. 52-56
    • Lyons, R.A.1    Saridogan, E.2    Djahanbakhch, O.3
  • 181
    • 0028808233 scopus 로고
    • Timing of sexual intercourse in relation to ovulation
    • Wilcox, A. J., Weinberg, C. R. & Baird, D. B. Timing of sexual intercourse in relation to ovulation. N. Engl. J. Med. 333, 7-11 (1995).
    • (1995) N. Engl. J. Med , vol.333 , pp. 7-11
    • Wilcox, A.J.1    Weinberg, C.R.2    Baird, D.B.3
  • 182
    • 84959065227 scopus 로고    scopus 로고
    • Sperm storage in the female reproductive tract
    • Holt, W. V. & Fazeli, A. Sperm storage in the female reproductive tract. Annu. Rev. Anim. Biosci. 4, 291-310 (2016).
    • (2016) Annu. Rev. Anim. Biosci , vol.4 , pp. 291-310
    • Holt, W.V.1    Fazeli, A.2
  • 183
    • 0027760990 scopus 로고
    • Sperm numbers and distribution within the human fallopian tube around ovulation
    • Williams, M. et al. Sperm numbers and distribution within the human fallopian tube around ovulation. Hum. Reprod. 8, 2019-2026 (1993).
    • (1993) Hum. Reprod , vol.8 , pp. 2019-2026
    • Williams, M.1
  • 184
    • 0016717597 scopus 로고
    • A scanning electron microscopic study of rabbit spermatozoa in the female reproductive tract following coitus
    • Motta, P. & Van Blerkom, J. A scanning electron microscopic study of rabbit spermatozoa in the female reproductive tract following coitus. Cell Tissue Res. 163, 29-44 (1975).
    • (1975) Cell Tissue Res , vol.163 , pp. 29-44
    • Motta, P.1    Van Blerkom, J.2
  • 185
    • 0028920010 scopus 로고
    • Andrology: The interaction in vitro of human spermatozoa with epithelial cells from the human uterine (Fallopian) tube
    • Pacey, A. A. et al. Andrology: The interaction in vitro of human spermatozoa with epithelial cells from the human uterine (Fallopian) tube. Hum. Reprod 10, 360-366 (1995).
    • (1995) Hum. Reprod , vol.10 , pp. 360-366
    • Pacey, A.A.1
  • 186
    • 84863904876 scopus 로고    scopus 로고
    • Ultrastructural interaction between spermatozoon and human oviductal cells vitro
    • Vigil, P., Salgado, A. M. & Cortés, M. E. Ultrastructural interaction between spermatozoon and human oviductal cells in vitro. J. Electron. Microsc. (Tokyo) 61, 123-126 (2012).
    • (2012) J. Electron. Microsc. (Tokyo) , vol.61 , pp. 123-126
    • Vigil, P.1    Salgado, A.M.2    Cortés, M.E.3
  • 187
    • 0033795439 scopus 로고    scopus 로고
    • Importance of sperm-To-epithelial cell contact for the capacitation of human spermatozoa in fallopian tube epithelial cell cocultures
    • Kervancioglu, E. M., Saridogan, E., John Aitken, R. & Djahanbakhch, O. Importance of sperm-To-epithelial cell contact for the capacitation of human spermatozoa in fallopian tube epithelial cell cocultures. Fertil. Steril. 74, 780-784 (2000).
    • (2000) Fertil. Steril , vol.74 , pp. 780-784
    • Kervancioglu, E.M.1    Saridogan, E.2    John Aitken, R.3    Djahanbakhch, O.4
  • 188
    • 0029835199 scopus 로고    scopus 로고
    • Sperm interaction with human oviductal cells vitro
    • Morales, P., Palma, V., Salgado, A. M. & Villalon, M. Sperm interaction with human oviductal cells in vitro. Hum. Reprod. 11, 1504-1509 (1996).
    • (1996) Hum. Reprod , vol.11 , pp. 1504-1509
    • Morales, P.1    Palma, V.2    Salgado, A.M.3    Villalon, M.4
  • 189
    • 0033058988 scopus 로고    scopus 로고
    • Sperm-oviduct interaction: Induction of capacitation and preferential binding of uncapacitated spermatozoa to oviductal epithelial cells in porcine species
    • Fazeli, A., Duncan, A. E., Watson, P. F. & Holt, W. V. Sperm-oviduct interaction: Induction of capacitation and preferential binding of uncapacitated spermatozoa to oviductal epithelial cells in porcine species. Biol. Reprod. 60, 879-886 (1999).
    • (1999) Biol. Reprod , vol.60 , pp. 879-886
    • Fazeli, A.1    Duncan, A.E.2    Watson, P.F.3    Holt, W.V.4
  • 190
    • 0028839829 scopus 로고
    • Characterization of the oviductal sperm reservoir in cattle
    • Lefebvre, R. et al. Characterization of the oviductal sperm reservoir in cattle. Biol. Reprod. 53, 1066-1074 (1995).
    • (1995) Biol. Reprod , vol.53 , pp. 1066-1074
    • Lefebvre, R.1
  • 191
    • 0028091697 scopus 로고
    • Structure and function of the ductuli efferentes: A review
    • Ilio, K. Y. & Hess, R. A. Structure and function of the ductuli efferentes: A review. Microsc. Res. Tech. 29, 432-467 (1994).
    • (1994) Microsc. Res. Tech , vol.29 , pp. 432-467
    • Ilio, K.Y.1    Hess, R.A.2
  • 192
    • 84904613815 scopus 로고    scopus 로고
    • Ductuli efferentes of the male Golden Syrian hamster reproductive tract
    • Ford, J. J., Carnes, K. & Hess, R. A. Ductuli efferentes of the male Golden Syrian hamster reproductive tract. Andrology 2, 510-520 (2014).
    • (2014) Andrology , vol.2 , pp. 510-520
    • Ford, J.J.1    Carnes, K.2    Hess, R.A.3
  • 193
    • 0025813107 scopus 로고
    • Organization of tubules in the human caput epididymidis and the ultrastructure of their epithelia
    • Yeung, C. H., Cooper, T. G., Bergmann, M. & Schulze, H. Organization of tubules in the human caput epididymidis and the ultrastructure of their epithelia. Am. J. Anat. 191, 261-279 (1991).
    • (1991) Am. J. Anat , vol.191 , pp. 261-279
    • Yeung, C.H.1    Cooper, T.G.2    Bergmann, M.3    Schulze, H.4
  • 195
    • 84995545624 scopus 로고    scopus 로고
    • The human epididymis: Its function in sperm maturation
    • Sullivan, R. & Mieusset, R. The human epididymis: its function in sperm maturation. Hum. Reprod. Update 22, 574-587 (2016).
    • (2016) Hum. Reprod. Update , vol.22 , pp. 574-587
    • Sullivan, R.1    Mieusset, R.2
  • 196
    • 84987593440 scopus 로고
    • On the mechanism for flow in the efferent ducts fluid
    • Winet, H. On the mechanism for flow in the efferent ducts fluid. J. Androl. 1, 304-311 (1980).
    • (1980) J. Androl , vol.1 , pp. 304-311
    • Winet, H.1
  • 197
    • 77049146717 scopus 로고
    • Some functions of the caput epididymis
    • Mason, K. & Shaver, S. Some functions of the caput epididymis. Ann. NY Acad. Sci. 55, 585-593 (1952).
    • (1952) Ann. NY Acad. Sci , vol.55 , pp. 585-593
    • Mason, K.1    Shaver, S.2
  • 198
    • 0017710455 scopus 로고
    • Testicular contractile cells and sperm transport
    • Hargrove, J. L., MacIndoe, J. H. & Ellis, L. C. Testicular contractile cells and sperm transport. Fertil. Steril. 28, 1146-1157 (1977).
    • (1977) Fertil. Steril , vol.28 , pp. 1146-1157
    • Hargrove, J.L.1    MacIndoe, J.H.2    Ellis, L.C.3
  • 199
    • 0019787193 scopus 로고
    • In-vitro spontaneous electrical activity of rat efferent ductules
    • Talo, A. In-vitro spontaneous electrical activity of rat efferent ductules. J. Reprod. Fertil. 63, 17-20 (1981).
    • (1981) J. Reprod. Fertil , vol.63 , pp. 17-20
    • Talo, A.1
  • 200
    • 84937571614 scopus 로고    scopus 로고
    • Development and functions of the choroid plexus-cerebrospinal fluid system
    • Lun, M. P., Monuki, E. S. & Lehtinen, M. K. Development and functions of the choroid plexus-cerebrospinal fluid system. Nat. Rev. Neurosci. 16, 445-457 (2015).
    • (2015) Nat. Rev. Neurosci , vol.16 , pp. 445-457
    • Lun, M.P.1    Monuki, E.S.2    Lehtinen, M.K.3
  • 201
    • 12144265005 scopus 로고
    • Ependymal cilia: Distribution and activity in the adult human brain
    • Worthington, W. C. & Cathcart, R. S. Ependymal cilia: distribution and activity in the adult human brain. Science 139, 221-222 (1963).
    • (1963) Science , vol.139 , pp. 221-222
    • Worthington, W.C.1    Cathcart, R.S.2
  • 202
    • 0014032418 scopus 로고
    • Ciliary currents on ependymal surfaces
    • Worthington, W. C. & Cathcart, R. S. Ciliary currents on ependymal surfaces. Ann. NY Acad. Sci. 130, 944-950 (1966).
    • (1966) Ann. NY Acad. Sci , vol.130 , pp. 944-950
    • Worthington, W.C.1    Cathcart, R.S.2
  • 204
    • 84924273728 scopus 로고    scopus 로고
    • Mechanisms of fluid movement into, through and out of the brain: Evaluation of the evidence
    • Hladky, S. B. & Barrand, M. A. Mechanisms of fluid movement into, through and out of the brain: evaluation of the evidence. Fluids Barriers CNS 11, 26 (2014).
    • (2014) Fluids Barriers CNS , vol.11 , pp. 26
    • Hladky, S.B.1    Barrand, M.A.2
  • 205
    • 84896953834 scopus 로고    scopus 로고
    • Flow induced by ependymal cilia dominates near-wall cerebrospinal fluid dynamics in the lateral ventricles
    • Siyahhan, B. et al. Flow induced by ependymal cilia dominates near-wall cerebrospinal fluid dynamics in the lateral ventricles. J. R. Soc. Interface 11, 20131189 (2014).
    • (2014) J. R. Soc. Interface , vol.11 , pp. 20131189
    • Siyahhan, B.1
  • 206
    • 84979017192 scopus 로고    scopus 로고
    • Cilia-based flow network in the brain ventricles
    • Faubel, R., Westendorf, C., Bodenschatz, E. & Eichele, G. Cilia-based flow network in the brain ventricles. Science 353, 176-178 (2016).
    • (2016) Science , vol.353 , pp. 176-178
    • Faubel, R.1    Westendorf, C.2    Bodenschatz, E.3    Eichele, G.4
  • 207
    • 18644362790 scopus 로고    scopus 로고
    • Computational modeling of the mechanical behavior of the cerebrospinal fluid system
    • Kurtcuoglu, V., Poulikakos, D. & Ventikos, Y. Computational modeling of the mechanical behavior of the cerebrospinal fluid system. J. Biomech. Eng. 127, 264-269 (2005).
    • (2005) J. Biomech. Eng , vol.127 , pp. 264-269
    • Kurtcuoglu, V.1    Poulikakos, D.2    Ventikos, Y.3
  • 208
    • 33947592243 scopus 로고    scopus 로고
    • Computational investigation of subject-specific cerebrospinal fluid flow in the third ventricle and aqueduct of Sylvius
    • Kurtcuoglu, V. et al. Computational investigation of subject-specific cerebrospinal fluid flow in the third ventricle and aqueduct of Sylvius. J. Biomech. 40, 1235-1245 (2007).
    • (2007) J. Biomech , vol.40 , pp. 1235-1245
    • Kurtcuoglu, V.1
  • 209
    • 35548958704 scopus 로고    scopus 로고
    • Mixing and modes of mass transfer in the third cerebral ventricle: A computational analysis
    • Kurtcuoglu, V., Soellinger, M., Summers, P., Poulikakos, D. & Boesiger, P. Mixing and modes of mass transfer in the third cerebral ventricle: A computational analysis. J. Biomech. Eng. 129, 695-702 (2007).
    • (2007) J. Biomech. Eng , vol.129 , pp. 695-702
    • Kurtcuoglu, V.1    Soellinger, M.2    Summers, P.3    Poulikakos, D.4    Boesiger, P.5
  • 210
    • 31944434903 scopus 로고    scopus 로고
    • New neurons follow the flow of cerebrospinal fluid in the adult brain
    • Sawamoto, K. et al. New neurons follow the flow of cerebrospinal fluid in the adult brain. Science 311, 629-632 (2006).
    • (2006) Science , vol.311 , pp. 629-632
    • Sawamoto, K.1
  • 211
    • 77955490391 scopus 로고    scopus 로고
    • New neurons clear the path of astrocytic processes for their rapid migration in the adult brain
    • Kaneko, N. et al. New neurons clear the path of astrocytic processes for their rapid migration in the adult brain. Neuron 5, 213-223 (2010).
    • (2010) Neuron , vol.5 , pp. 213-223
    • Kaneko, N.1
  • 212
    • 84891035250 scopus 로고    scopus 로고
    • Influence of respiration on cerebrospinal fluid movement using magnetic resonance spin labeling
    • Yamada, S. et al. Influence of respiration on cerebrospinal fluid movement using magnetic resonance spin labeling. Fluids Barriers CNS 10, 36 (2013).
    • (2013) Fluids Barriers CNS , vol.10 , pp. 36
    • Yamada, S.1
  • 213
    • 79952215175 scopus 로고    scopus 로고
    • The cerebrospinal fluid provides a proliferative niche for neural progenitor cells
    • Lehtinen, M. K. et al. The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron 69, 893-905 (2011).
    • (2011) Neuron , vol.69 , pp. 893-905
    • Lehtinen, M.K.1
  • 214
    • 50849113768 scopus 로고    scopus 로고
    • Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain
    • Mirzadeh, Z., Merkle, F. T., Soriano-Navarro, M., Garcia-Verdugo, J. M. & Alvarez-Buylla, A. Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. Cell Stem Cell 3, 265-278 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 265-278
    • Mirzadeh, Z.1    Merkle, F.T.2    Soriano-Navarro, M.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 215
    • 0034517812 scopus 로고    scopus 로고
    • Noggin antagonizes BMP signaling to create a niche for adult neurogenesis
    • Lim, D. A. et al. Noggin antagonizes BMP signaling to create a niche for adult neurogenesis. Neuron 28, 713-726 (2000).
    • (2000) Neuron , vol.28 , pp. 713-726
    • Lim, D.A.1
  • 216
    • 77956241246 scopus 로고    scopus 로고
    • Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling
    • Kokovay, E. et al. Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling. Cell Stem Cell 7, 163-173 (2010).
    • (2010) Cell Stem Cell , vol.7 , pp. 163-173
    • Kokovay, E.1
  • 217
    • 33344455016 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is a niche signal for neural stem cell renewal
    • Ramírez-Castillejo, C. et al. Pigment epithelium-derived factor is a niche signal for neural stem cell renewal. Nat. Neurosci. 9, 331-339 (2006).
    • (2006) Nat. Neurosci , vol.9 , pp. 331-339
    • Ramírez-Castillejo, C.1
  • 218
    • 70450258365 scopus 로고    scopus 로고
    • Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone
    • Andreu-Agulló, C., Morante-Redolat, J. M., Delgado, A. C. & Fariñas, I. Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone. Nat. Neurosci. 12, 1514-1523 (2009).
    • (2009) Nat. Neurosci , vol.12 , pp. 1514-1523
    • Andreu-Agulló, C.1    Morante-Redolat, J.M.2    Delgado, A.C.3    Fariñas, I.4
  • 219
    • 0019890725 scopus 로고
    • Primary cilia dyskinesia
    • Sleight, M. Primary cilia dyskinesia. Lancet 318, 476 (1981).
    • (1981) Lancet , vol.318 , pp. 476
    • Sleight, M.1
  • 220
    • 35448961665 scopus 로고    scopus 로고
    • When cilia go bad: Cilia defects and ciliopathies
    • Fliegauf, M., Benzing, T. & Omran, H. When cilia go bad: cilia defects and ciliopathies. Nat. Rev. Mol. Cell Biol. 8, 880-893 (2007).
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 880-893
    • Fliegauf, M.1    Benzing, T.2    Omran, H.3
  • 222
    • 0025983457 scopus 로고
    • Ultrastructural ciliary defects in children with recurrent infections of the lower respiratory tract
    • Barlocco, E. G. et al. Ultrastructural ciliary defects in children with recurrent infections of the lower respiratory tract. Pediatr. Pulmonol. 10, 11-17 (1991).
    • (1991) Pediatr. Pulmonol , vol.10 , pp. 11-17
    • Barlocco, E.G.1
  • 223
    • 84867272647 scopus 로고    scopus 로고
    • Ciliary aplasia associated with hydrocephalus: An extremely rare occurrence
    • Berlucchi, M. et al. Ciliary aplasia associated with hydrocephalus: An extremely rare occurrence. Eur. Arch. Otorhinolaryngol. 269, 2295-2299 (2012).
    • (2012) Eur. Arch. Otorhinolaryngol , vol.269 , pp. 2295-2299
    • Berlucchi, M.1
  • 225
    • 22244443066 scopus 로고    scopus 로고
    • Primary ciliary dyskinesia: A review
    • Carlén, B. & Stenram, U. Primary ciliary dyskinesia: A review. Ultrastruct. Pathol. 29, 217-220 (2005).
    • (2005) Ultrastruct. Pathol , vol.29 , pp. 217-220
    • Carlén, B.1    Stenram, U.2
  • 226
    • 0024264398 scopus 로고
    • Cilia-lacking respiratory cells in ciliary aplasia
    • de Santi, M. M. et al. Cilia-lacking respiratory cells in ciliary aplasia. Biol. Cell 64, 67-70 (1988).
    • (1988) Biol. Cell , vol.64 , pp. 67-70
    • De Santi, M.M.1
  • 227
    • 0026902393 scopus 로고
    • Aplasia of respiratory tract cilia
    • DeBoeck, K. et al. Aplasia of respiratory tract cilia. Pediatr. Pulmonol. 13, 259-265 (1992).
    • (1992) Pediatr. Pulmonol , vol.13 , pp. 259-265
    • DeBoeck, K.1
  • 228
    • 0027637074 scopus 로고
    • New associations of primary ciliary dyskinesia syndrome
    • Engesaeth, V. G., Warner, J. O. & Bush, M. D. New associations of primary ciliary dyskinesia syndrome. Pediatr. Pulmonol. 16, 9-12 (1993).
    • (1993) Pediatr. Pulmonol , vol.16 , pp. 9-12
    • Engesaeth, V.G.1    Warner, J.O.2    Bush, M.D.3
  • 229
    • 0021242057 scopus 로고
    • Absence of cilia and basal bodies with predominance of brush cells in the respiratory mucosa from a patient with immotile cilia syndrome
    • Gordon, R. E. & Kattan, M. Absence of cilia and basal bodies with predominance of brush cells in the respiratory mucosa from a patient with immotile cilia syndrome. Ultrastruct. Pathol. 6, 45-49 (1984).
    • (1984) Ultrastruct. Pathol , vol.6 , pp. 45-49
    • Gordon, R.E.1    Kattan, M.2
  • 230
    • 0021094739 scopus 로고
    • Aplasia of respiratory tract cilia
    • Gotz, M. & Stockinger, L. Aplasia of respiratory tract cilia. Lancet 321, 1283 (1983).
    • (1983) Lancet , vol.321 , pp. 1283
    • Gotz, M.1    Stockinger, L.2
  • 231
    • 0021967617 scopus 로고
    • Ultrastructural observations on basal apparatus of respiratory cilia in immotile cilia syndrome
    • Lungarella, G., de Santi, M. M., Palestri, R. & Tosi, P. Ultrastructural observations on basal apparatus of respiratory cilia in immotile cilia syndrome. Eur. J. Respir. Dis. 66, 165-172 (1985).
    • (1985) Eur. J. Respir. Dis , vol.66 , pp. 165-172
    • Lungarella, G.1    De Santi, M.M.2    Palestri, R.3    Tosi, P.4
  • 233
    • 0033759386 scopus 로고    scopus 로고
    • No deleterious mutations in the FOXJ1 (aliasHFH-4) gene in patients with primary ciliary dyskinesia (PCD
    • Maiti, A. et al. No deleterious mutations in the FOXJ1 (aliasHFH-4) gene in patients with primary ciliary dyskinesia (PCD). Cytogenet. Cell Genet. 90, 119-122 (2000).
    • (2000) Cytogenet. Cell Genet , vol.90 , pp. 119-122
    • Maiti, A.1
  • 234
    • 0024342840 scopus 로고
    • Congenital ciliary aplasia in two siblings
    • Richard, S. et al. Congenital ciliary aplasia in two siblings. Pathol. Res. Pract. 185, 181-183 (1989).
    • (1989) Pathol. Res. Pract , vol.185 , pp. 181-183
    • Richard, S.1
  • 236
    • 47149112740 scopus 로고    scopus 로고
    • Candidate gene analysis in three families with acilia syndrome
    • Wessels, M. W. et al. Candidate gene analysis in three families with acilia syndrome. Am. J. Med. Genet. A 146, 1765-1767 (2008).
    • (2008) Am. J. Med. Genet. A , vol.146 , pp. 1765-1767
    • Wessels, M.W.1
  • 237
    • 0021808210 scopus 로고
    • Familial nasal acilia syndrome
    • Babin, R. W. & Kavanagh, K. T. Familial nasal acilia syndrome. South. Med. J. 78, 737-739 (1985).
    • (1985) South. Med. J , vol.78 , pp. 737-739
    • Babin, R.W.1    Kavanagh, K.T.2
  • 238
    • 0023127358 scopus 로고
    • Aplasia of nasal cilia with situs inversus, azoospermia and normal sperm flagella: A unique variant of the immotile cilia syndrome
    • Matwijiw, I., Thliveris, J. A. & Faiman, C. Aplasia of nasal cilia with situs inversus, azoospermia and normal sperm flagella: A unique variant of the immotile cilia syndrome. J. Urol. 137, 522-524 (1987).
    • (1987) J. Urol , vol.137 , pp. 522-524
    • Matwijiw, I.1    Thliveris, J.A.2    Faiman, C.3
  • 239
    • 0022330894 scopus 로고
    • Absence of cilia and basal bodies with predominance of brush cells in the respiratory mucosa from a patient with immotile cilia syndrome
    • Cerezo, L. & Price, G. Absence of cilia and basal bodies with predominance of brush cells in the respiratory mucosa from a patient with immotile cilia syndrome. Ultrastruct. Pathol. 8, 381-382 (1985).
    • (1985) Ultrastruct. Pathol , vol.8 , pp. 381-382
    • Cerezo, L.1    Price, G.2
  • 240
    • 77649190846 scopus 로고    scopus 로고
    • Ependymal cells: Biology and pathology
    • Del Bigio, M. R. Ependymal cells: biology and pathology. Acta Neuropathol. 119, 55-73 (2010).
    • (2010) Acta Neuropathol , vol.119 , pp. 55-73
    • Del Bigio, M.R.1
  • 242
    • 5744244393 scopus 로고    scopus 로고
    • Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation
    • Ibañez-Tallon, I. et al. Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation. Hum. Mol. Genet. 13, 2133-2141 (2004).
    • (2004) Hum. Mol. Genet , vol.13 , pp. 2133-2141
    • Ibañez-Tallon, I.1
  • 243
    • 4444273131 scopus 로고    scopus 로고
    • Absent inner dynein arms in a fetus with familial hydrocephalus-situs abnormality
    • Kosaki, K. et al. Absent inner dynein arms in a fetus with familial hydrocephalus-situs abnormality. Am. J. Med. Genet. A 129A, 308-311 (2004).
    • (2004) Am. J. Med. Genet. A , vol.129 , pp. 308-311
    • Kosaki, K.1
  • 244
    • 0018305742 scopus 로고
    • Kartageners syndrome and the syndrome of immotile cilia
    • Rott, H. D. Kartageners syndrome and the syndrome of immotile cilia. Hum. Genet. 46, 249-261 (1979).
    • (1979) Hum. Genet , vol.46 , pp. 249-261
    • Rott, H.D.1
  • 245
    • 84859073267 scopus 로고    scopus 로고
    • Primary ciliary dyskinesia and hydrocephalus with aqueductal stenosis
    • Vieira, J. P., Lopes, P. & Silva, R. Primary ciliary dyskinesia and hydrocephalus with aqueductal stenosis. J. Child Neurol. 27, 938-941 (2012).
    • (2012) J. Child Neurol , vol.27 , pp. 938-941
    • Vieira, J.P.1    Lopes, P.2    Silva, R.3
  • 246
    • 0027772235 scopus 로고
    • Immotile cilia syndrome associated with hydrocephalus and precocious puberty: A case report
    • Picco, P. et al. Immotile cilia syndrome associated with hydrocephalus and precocious puberty: A case report. Eur. J. Pediatr. Surg. 3 (Suppl. 1), 20-21 (1993).
    • (1993) Eur. J. Pediatr. Surg , vol.3 , pp. 20-21
    • Picco, P.1
  • 247
    • 0022541080 scopus 로고
    • Hydrocephalus in Kartageners syndrome
    • Jabourian, Z. et al. Hydrocephalus in Kartageners syndrome. Ear Nose Throat J. 65, 468-472 (1986).
    • (1986) Ear Nose Throat J , vol.65 , pp. 468-472
    • Jabourian, Z.1
  • 248
    • 0037339837 scopus 로고    scopus 로고
    • Mild fetal cerebral ventriculomegaly as a prenatal sonographic marker for Kartagener syndrome
    • Wessels, M. W., den Hollander, N. S. & Willems, P. J. Mild fetal cerebral ventriculomegaly as a prenatal sonographic marker for Kartagener syndrome. Prenat. Diagn. 23, 239-242 (2003).
    • (2003) Prenat. Diagn , vol.23 , pp. 239-242
    • Wessels, M.W.1    Den Hollander, N.S.2    Willems, P.J.3
  • 249
    • 0023919949 scopus 로고
    • Primary ciliary dyskinesia: Cytological and clinical features
    • Greenstone, M., Rutman, A., Dewar, A., Mackay, I. & Cole, P. J. Primary ciliary dyskinesia: cytological and clinical features. Q. J. Med. 67, 405-423 (1988).
    • (1988) Q. J. Med , vol.67 , pp. 405-423
    • Greenstone, M.1    Rutman, A.2    Dewar, A.3    Mackay, I.4    Cole, P.J.5
  • 250
    • 0038038284 scopus 로고    scopus 로고
    • Alzheimers disease, normal-pressure hydrocephalus, and senescent changes in CSF circulatory physiology: A hypothesis
    • Silverberg, G. D., Mayo, M., Saul, T., Rubenstein, E. & McGuire, D. Alzheimers disease, normal-pressure hydrocephalus, and senescent changes in CSF circulatory physiology: A hypothesis. Lancet Neurol. 2, 506-511 (2003).
    • (2003) Lancet Neurol , vol.2 , pp. 506-511
    • Silverberg, G.D.1    Mayo, M.2    Saul, T.3    Rubenstein, E.4    McGuire, D.5
  • 251
    • 44949263894 scopus 로고    scopus 로고
    • Multiplicity of cerebrospinal fluid functions: New challenges in health and disease
    • Johanson, C. E. et al. Multiplicity of cerebrospinal fluid functions: new challenges in health and disease. Cerebrospinal Fluid Res. 5, 10 (2008).
    • (2008) Cerebrospinal Fluid Res , vol.5 , pp. 10
    • Johanson, C.E.1
  • 252
    • 84876786043 scopus 로고    scopus 로고
    • GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimers disease
    • Cruchaga, C. et al. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimers disease. Neuron 78, 256-268 (2013).
    • (2013) Neuron , vol.78 , pp. 256-268
    • Cruchaga, C.1
  • 253
    • 84888317489 scopus 로고    scopus 로고
    • Meta-Analysis of 74, 046 individuals identifies 11 new susceptibility loci for Alzheimers disease
    • Lambert, J. C. et al. Meta-Analysis of 74, 046 individuals identifies 11 new susceptibility loci for Alzheimers disease. Nat. Genet. 45, 1452-1458 (2013).
    • (2013) Nat. Genet , vol.45 , pp. 1452-1458
    • Lambert, J.C.1
  • 254
    • 80555136825 scopus 로고    scopus 로고
    • Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease
    • Keryer, G. et al. Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease. J. Clin. Invest.121, 4372-4382 (2011).
    • (2011) J. Clin. Invest , vol.121 , pp. 4372-4382
    • Keryer, G.1
  • 255
    • 0017896357 scopus 로고
    • Absence of dynein arms in cilia of endocervical cells in a fertile woman
    • Bleau, G., Richer, C. L. & Bousquet, D. Absence of dynein arms in cilia of endocervical cells in a fertile woman. Fertil. Steril. 30, 362-363 (1978).
    • (1978) Fertil. Steril , vol.30 , pp. 362-363
    • Bleau, G.1    Richer, C.L.2    Bousquet, D.3
  • 256
    • 0018394857 scopus 로고
    • Fertility of a woman with nonfunctional ciliated cells in the fallopian tubes
    • Jean, Y., Langlais, J., Roberts, K. D., Chapdelaine, A. & Bleau, G. Fertility of a woman with nonfunctional ciliated cells in the fallopian tubes. Fertil. Steril. 31, 349-350 (1979).
    • (1979) Fertil. Steril , vol.31 , pp. 349-350
    • Jean, Y.1    Langlais, J.2    Roberts, K.D.3    Chapdelaine, A.4    Bleau, G.5
  • 257
    • 38349131348 scopus 로고    scopus 로고
    • In vitro fertilization in two patients with Kartageners syndrome and infertility
    • Abu-Musa, A., Nassar, A. & Usta, I. In vitro fertilization in two patients with Kartageners syndrome and infertility. Gynecol. Obstet. Invest. 65, 29-31 (2008).
    • (2008) Gynecol. Obstet. Invest , vol.65 , pp. 29-31
    • Abu-Musa, A.1    Nassar, A.2    Usta, I.3
  • 258
    • 0031039899 scopus 로고    scopus 로고
    • Function and structure of cilia in the fallopian tube of an infertile woman with Kartageners syndrome
    • Halbert, S. A., Patton, D. L., Zarutskie, P. W. & Soules, M. R. Function and structure of cilia in the fallopian tube of an infertile woman with Kartageners syndrome. Hum. Reprod. 12, 55-58 (1997).
    • (1997) Hum. Reprod , vol.12 , pp. 55-58
    • Halbert, S.A.1    Patton, D.L.2    Zarutskie, P.W.3    Soules, M.R.4
  • 259
    • 0024583559 scopus 로고
    • Ciliary ultrastructure of respiratory and fallopian tube epithelium in a sterile woman with Kartageners syndrome. A quantitative estimation
    • Lurie, M. et al. Ciliary ultrastructure of respiratory and fallopian tube epithelium in a sterile woman with Kartageners syndrome. A quantitative estimation. Chest 95, 578-581 (1989).
    • (1989) Chest , vol.95 , pp. 578-581
    • Lurie, M.1
  • 260
    • 0033636846 scopus 로고    scopus 로고
    • Chronic cough and infertility: A report of two cases
    • McLean, L. & Claman, P. Chronic cough and infertility: A report of two cases. Fertil. Steril. 74, 1251-1253 (2000).
    • (2000) Fertil. Steril , vol.74 , pp. 1251-1253
    • McLean, L.1    Claman, P.2
  • 261
    • 0021050029 scopus 로고
    • Absence of dynein arms in endometrial cilia: Cause of infertility?
    • Pedersen, H. Absence of dynein arms in endometrial cilia: cause of infertility? Acta Obstet. Gynecol. Scand. 62, 625-627 (1983).
    • (1983) Acta Obstet. Gynecol. Scand , vol.62 , pp. 625-627
    • Pedersen, H.1
  • 262
    • 0031672536 scopus 로고    scopus 로고
    • A successful pregnancy with in vitro fertilization and embryo transfer in an infertile woman with Kartageners syndrome: A case report
    • Lin, T. K. et al. A successful pregnancy with in vitro fertilization and embryo transfer in an infertile woman with Kartageners syndrome: A case report. J. Assist. Reprod. Genet. 15, 625-627 (1998).
    • (1998) J. Assist. Reprod. Genet , vol.15 , pp. 625-627
    • Lin, T.K.1
  • 263
    • 0020620860 scopus 로고
    • Male and female infertility problems in the immotile-cilia syndrome
    • Afzelius, B. A. & Eliasson, R. Male and female infertility problems in the immotile-cilia syndrome. Eur. J. Respir. Dis. Suppl. 127, 144-147 (1983).
    • (1983) Eur. J. Respir. Dis. Suppl , vol.127 , pp. 144-147
    • Afzelius, B.A.1    Eliasson, R.2
  • 264
    • 45749142096 scopus 로고    scopus 로고
    • Ectopic pregnancy in primary ciliary dyskinesia
    • Blyth, M. & Wellesley, D. Ectopic pregnancy in primary ciliary dyskinesia. J. Obstet. Gynaecol. 28, 358 (2008).
    • (2008) J. Obstet. Gynaecol , vol.28 , pp. 358
    • Blyth, M.1    Wellesley, D.2
  • 265
    • 84886402463 scopus 로고    scopus 로고
    • Recent advances in diagnostics, genetics, and characterization of clinical disease
    • Knowles, M., Daniels, L., Davis, S., Zariwala, M. & Leigh, M. Primary ciliary dyskinesia. Recent advances in diagnostics, genetics, and characterization of clinical disease. Am. J. Respir. Crit. Care Med. 188, 913-922 (2013).
    • (2013) Am. J. Respir. Crit. Care Med , vol.188 , pp. 913-922
    • Knowles, M.1    Daniels, L.2    Davis, S.3    Zariwala, M.4    Dyskinesia, L.M.5
  • 266
    • 84898598655 scopus 로고    scopus 로고
    • Mucociliary clearance: Pathophysiological aspects
    • Munkholm, M. & Mortensen, J. Mucociliary clearance: pathophysiological aspects. Clin. Physiol. Funct. Imaging 34, 171-177 (2014).
    • (2014) Clin. Physiol. Funct. Imaging , vol.34 , pp. 171-177
    • Munkholm, M.1    Mortensen, J.2
  • 268
    • 0014342518 scopus 로고
    • Ciliated human renal proximal tubular cells. Observations in three cases of hypercalcemia
    • Duffy, J. L. & Suzuki, Y. Ciliated human renal proximal tubular cells. Observations in three cases of hypercalcemia. Am. J. Pathol. 53, 609-616 (1968).
    • (1968) Am. J. Pathol , vol.53 , pp. 609-616
    • Duffy, J.L.1    Suzuki, Y.2
  • 269
    • 20444375118 scopus 로고    scopus 로고
    • Detection of proximal tubular motile cilia in a patient with renal sarcoidosis associated with hypercalcemia
    • Ong, A. C. M. & Wagner, B. Detection of proximal tubular motile cilia in a patient with renal sarcoidosis associated with hypercalcemia. Am. J. Kidney Dis. 45, 1096-1099 (2005).
    • (2005) Am. J. Kidney Dis , vol.45 , pp. 1096-1099
    • Ong, A.C.M.1    Wagner, B.2
  • 270
    • 0015987456 scopus 로고
    • Ciliated renal tubular epithelium in congenital nephrosis
    • Datsis, S. A. & Boman, I. A. Ciliated renal tubular epithelium in congenital nephrosis. Beitr. Pathol. 151, 297-303 (1974).
    • (1974) Beitr. Pathol , vol.151 , pp. 297-303
    • Datsis, S.A.1    Boman, I.A.2
  • 271
    • 0016275499 scopus 로고
    • Cilia in lupus nephritis
    • Larsen, T. E. & Ghadially, F. N. Cilia in lupus nephritis. J. Pathol. 114, 69-73 (1974).
    • (1974) J. Pathol , vol.114 , pp. 69-73
    • Larsen, T.E.1    Ghadially, F.N.2
  • 272
    • 0021252217 scopus 로고
    • Ultrastructural study of the ciliated cells from renal tubular epithelium in acute progressive glomerulonephritis
    • Lungarella, G., de Santi, M. M. & Tosi, P. Ultrastructural study of the ciliated cells from renal tubular epithelium in acute progressive glomerulonephritis. Ultrastruct. Pathol. 6, 1-7 (1984).
    • (1984) Ultrastruct. Pathol , vol.6 , pp. 1-7
    • Lungarella, G.1    De Santi, M.M.2    Tosi, P.3
  • 273
    • 0023941351 scopus 로고
    • Scanning electron microscopic observations on the epithelium of the human spongy urethra
    • Zecchi-Orlandini, S., Gulisano, M., Orlandini, G. E. & Holstein, A. F. Scanning electron microscopic observations on the epithelium of the human spongy urethra. Andrologia 20, 132-137 (1988).
    • (1988) Andrologia , vol.20 , pp. 132-137
    • Zecchi-Orlandini, S.1    Gulisano, M.2    Orlandini, G.E.3    Holstein, A.F.4
  • 274
    • 0023339429 scopus 로고
    • Scanning electron microscopic observations on the epithelium of the human prostatic urethra
    • Orlandini, G. E., Orlandini, S. Z., Holstein, A. F., Evangelisti, R. & Ponchietti, R. Scanning electron microscopic observations on the epithelium of the human prostatic urethra. Andrologia 19, 315-321 (1987).
    • (1987) Andrologia , vol.19 , pp. 315-321
    • Orlandini, G.E.1    Orlandini, S.Z.2    Holstein, A.F.3    Evangelisti, R.4    Ponchietti, R.5
  • 275
    • 0035723415 scopus 로고    scopus 로고
    • Ciliated epithelia in the urethra: Case report and literature review
    • Che, M., Ro, J. Y., Ordonez, N. G., Miller, R. W. & Ayala, A. G. Ciliated epithelia in the urethra: case report and literature review. Pathol. Int. 51, 892-895 (2001).
    • (2001) Pathol. Int , vol.51 , pp. 892-895
    • Che, M.1    Ro, J.Y.2    Ordonez, N.G.3    Miller, R.W.4    Ayala, A.G.5
  • 276
    • 0000354823 scopus 로고
    • Developmental changes in the oesophageal epithelium in man
    • Johns, B A. et al. Developmental changes in the oesophageal epithelium in man. J. Anat. 86, 431-442.4 (1952).
    • (1952) J. Anat , vol.86 , pp. 431-431e4
    • Johns, B.A.1
  • 277
    • 0041894379 scopus 로고
    • Organogenesis and growth of the gastroesophageal region in man
    • Botha, G. Organogenesis and growth of the gastroesophageal region in man. Anat. Rec. 133, 219-239 (1959).
    • (1959) Anat. Rec , vol.133 , pp. 219-239
    • Botha, G.1
  • 278
    • 0023235359 scopus 로고
    • Maturation of human fetal esophagus maintained in organ culture
    • Ménard, D. & Arsenault, P. Maturation of human fetal esophagus maintained in organ culture. Anat. Rec. 217, 348-354 (1987).
    • (1987) Anat. Rec , vol.217 , pp. 348-354
    • Ménard, D.1    Arsenault, P.2
  • 279
    • 3042960055 scopus 로고
    • The histogenesis of the esophagus and crop of the chicken, Turkey, Guinea fowl and pigeaon, with special reference to ciliated epithelium
    • Ivey, W. D. & Edgar, S. A. The histogenesis of the esophagus and crop of the chicken, turkey, guinea fowl and pigeaon, with special reference to ciliated epithelium. Anat. Rec. 114, 189-211 (1952).
    • (1952) Anat. Rec , vol.114 , pp. 189-211
    • Ivey, W.D.1    Edgar, S.A.2
  • 280
    • 0025849712 scopus 로고
    • Development of esophageal epithelium in the fetal and neonatal mouse
    • Raymond, C., Anne, V. & Millane, G. Development of esophageal epithelium in the fetal and neonatal mouse. Anat. Rec. 230, 225-234 (1991).
    • (1991) Anat. Rec , vol.230 , pp. 225-234
    • Raymond, C.1    Anne, V.2    Millane, G.3
  • 282
    • 84897454809 scopus 로고    scopus 로고
    • The adult macaque spinal cord central canal zone contains proliferative cells and closely resembles the human
    • Alfaro-Cervello, C. et al. The adult macaque spinal cord central canal zone contains proliferative cells and closely resembles the human. J. Comp. Neurol. 522, 1800-1817 (2014).
    • (2014) J. Comp. Neurol , vol.522 , pp. 1800-1817
    • Alfaro-Cervello, C.1
  • 283
    • 84975153575 scopus 로고    scopus 로고
    • Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature
    • Grimes, D. T. et al. Zebrafish models of idiopathic scoliosis link cerebrospinal fluid flow defects to spine curvature. Science 352, 1341-1344 (2016).
    • (2016) Science , vol.352 , pp. 1341-1344
    • Grimes, D.T.1
  • 284
    • 0015370814 scopus 로고
    • Scanning electron microscopic studies on rabbits spinal cord by resin cracking method
    • Ohtsuki, K. Scanning electron microscopic studies on rabbits spinal cord by resin cracking method. Arch. Histol. Jpn 34, 405-415 (1972).
    • (1972) Arch. Histol. Jpn , vol.34 , pp. 405-415
    • Ohtsuki, K.1
  • 285
    • 0016300363 scopus 로고
    • Number and polarity of the ependymal cilia in the central canal of some vertebrates
    • Nakayama, Y. & Kohno, K. Number and polarity of the ependymal cilia in the central canal of some vertebrates. J. Neurocytol. 3, 449-458 (1974).
    • (1974) J. Neurocytol , vol.3 , pp. 449-458
    • Nakayama, Y.1    Kohno, K.2
  • 286
    • 33947500073 scopus 로고    scopus 로고
    • Ciliary ultrastructure in two sisters with Kartageners syndrome
    • Tanaka, K. et al. Ciliary ultrastructure in two sisters with Kartageners syndrome. Med. Mol. Morphol. 40, 34-39 (2007).
    • (2007) Med. Mol. Morphol , vol.40 , pp. 34-39
    • Tanaka, K.1
  • 287
    • 84906242740 scopus 로고    scopus 로고
    • Situs inversus totalis-2 case reports
    • (in Spanish)
    • Juncos, C. et al. Situs inversus totalis-2 case reports. Rev. Chil. Pediatr. 85, 344-350 (in Spanish) (2014).
    • (2014) Rev. Chil. Pediatr , vol.85 , pp. 344-350
    • Juncos, C.1
  • 289
    • 73549122152 scopus 로고    scopus 로고
    • Multiple primary cilia modulate the fluid transcytosis in choroid plexus epithelium
    • Narita, K., Kawate, T., Kakinuma, N. & Takeda, S. Multiple primary cilia modulate the fluid transcytosis in choroid plexus epithelium. Traffic 11, 287-301 (2010).
    • (2010) Traffic , vol.11 , pp. 287-301
    • Narita, K.1    Kawate, T.2    Kakinuma, N.3    Takeda, S.4
  • 290
    • 29644441705 scopus 로고    scopus 로고
    • Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus
    • Banizs, B. et al. Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus. Development 132, 5329-5339 (2005).
    • (2005) Development , vol.132 , pp. 5329-5339
    • Banizs, B.1
  • 291
    • 84961390140 scopus 로고    scopus 로고
    • Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells
    • Li, L. et al. Sonic Hedgehog promotes proliferation of Notch-dependent monociliated choroid plexus tumour cells. Nat. Cell Biol. 18, 418-430 (2016).
    • (2016) Nat. Cell Biol , vol.18 , pp. 418-430
    • Li, L.1
  • 292
    • 0014872949 scopus 로고
    • Human choroid plexus: A light and electron microscopic study
    • Dohrmann, G. J. & Bucy, P. C. Human choroid plexus: A light and electron microscopic study. J. Neurosurg. 33, 506-516 (1970).
    • (1970) J. Neurosurg , vol.33 , pp. 506-516
    • Dohrmann, G.J.1    Bucy, P.C.2
  • 293
    • 0015904589 scopus 로고
    • A comparative ultrastructural study of the choroid plexuses of the immature pig
    • Davis, D. A., Lloyd, B. J. Jr & Milhorat, T. H. A comparative ultrastructural study of the choroid plexuses of the immature pig. Anat. Rec. 176, 443-454 (1973).
    • (1973) Anat. Rec , vol.176 , pp. 443-454
    • Davis, D.A.1    Lloyd, B.J.2    Milhorat, T.H.3
  • 294
    • 0013903418 scopus 로고
    • Ultrastructural organization of cilia and basal bodies of the epithelium of the choroid plexus in the chick embryo
    • Doolin, P. F. & Birge, W. J. Ultrastructural organization of cilia and basal bodies of the epithelium of the choroid plexus in the chick embryo. J. Cell Biol. 29, 333-345 (1966).
    • (1966) J. Cell Biol , vol.29 , pp. 333-345
    • Doolin, P.F.1    Birge, W.J.2
  • 295
    • 0018760445 scopus 로고
    • The choroid plexus of the mature and aging rat: The choroidal epithelium
    • Peters, A. & Swan, R. C. The choroid plexus of the mature and aging rat: The choroidal epithelium. Anat. Rec. 194, 325-353 (1979).
    • (1979) Anat. Rec , vol.194 , pp. 325-353
    • Peters, A.1    Swan, R.C.2
  • 296
    • 0014374176 scopus 로고
    • The surface of the choroid plexus cell under normal and experimental conditions
    • Santolaya, R. & Rodriguez Echandia, E. The surface of the choroid plexus cell under normal and experimental conditions. Z. Zellforsch. Mikrosk. Anat. 92, 43-51 (1968).
    • (1968) Z. Zellforsch. Mikrosk. Anat , vol.92 , pp. 43-51
    • Santolaya, R.1    Rodriguez Echandia, E.2
  • 297
    • 84871429222 scopus 로고    scopus 로고
    • Structural defects in cilia of the choroid plexus, subfornical organ and ventricular ependyma are associated with ventriculomegaly
    • Swiderski, R. E. et al. Structural defects in cilia of the choroid plexus, subfornical organ and ventricular ependyma are associated with ventriculomegaly. Fluids Barriers CNS 9, 22 (2012).
    • (2012) Fluids Barriers CNS , vol.9 , pp. 22
    • Swiderski, R.E.1
  • 298
    • 84964913264 scopus 로고    scopus 로고
    • Proteomic analysis of multiple primary cilia reveals a novel mode of ciliary development in mammals
    • Narita, K. et al. Proteomic analysis of multiple primary cilia reveals a novel mode of ciliary development in mammals. Biol. Open 1, 815-825 (2012).
    • (2012) Biol. Open , vol.1 , pp. 815-825
    • Narita, K.1
  • 299
    • 84890207009 scopus 로고    scopus 로고
    • Developmental changes in ciliary motility on choroid plexus epithelial cells during the perinatal period
    • Nonami, Y., Narita, K., Nakamura, H., Inoue, T. & Takeda, S. Developmental changes in ciliary motility on choroid plexus epithelial cells during the perinatal period. Cytoskeleton (Hoboken) 70, 797-803 (2013).
    • (2013) Cytoskeleton (Hoboken) , vol.70 , pp. 797-803
    • Nonami, Y.1    Narita, K.2    Nakamura, H.3    Inoue, T.4    Takeda, S.5
  • 300
    • 85009121725 scopus 로고    scopus 로고
    • Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories
    • 13759
    • Mirzadeh, Z. et al. Bi- and uniciliated ependymal cells define continuous floor-plate-derived tanycytic territories. Nat. Commun. 8, 13759 (2017).
    • (2017) Nat. Commun , vol.8
    • Mirzadeh, Z.1
  • 302
    • 48349122033 scopus 로고    scopus 로고
    • Spinal cord injury reveals multilineage differentiation of ependymal cells
    • Meletis, K. et al. Spinal cord injury reveals multilineage differentiation of ependymal cells. PLoS Biol. 6, 1494-1507 (2008).
    • (2008) PLoS Biol , vol.6 , pp. 1494-1507
    • Meletis, K.1
  • 303
    • 58149345025 scopus 로고    scopus 로고
    • Olfactory cilia: Our direct neuronal connection to the external world
    • McEwen, D. P., Jenkins, P. M. & Martens, J. R. Olfactory cilia: our direct neuronal connection to the external world. Curr. Top. Dev. Biol. 85, 333-370 (2008).
    • (2008) Curr. Top. Dev. Biol , vol.85 , pp. 333-370
    • McEwen, D.P.1    Jenkins, P.M.2    Martens, J.R.3
  • 304
    • 84923369097 scopus 로고    scopus 로고
    • Direct evidence for BBSome-Associated intraflagellar transport reveals distinct properties of native mammalian cilia
    • Williams, C. L. et al. Direct evidence for BBSome-Associated intraflagellar transport reveals distinct properties of native mammalian cilia. Nat. Commun. 5, 5813 (2014).
    • (2014) Nat. Commun , vol.5 , pp. 5813
    • Williams, C.L.1
  • 305
    • 84943456951 scopus 로고    scopus 로고
    • An olfactory cilia pattern in the mammalian nose ensures high sensitivity to odors
    • Challis, R. C. et al. An olfactory cilia pattern in the mammalian nose ensures high sensitivity to odors. Curr. Biol. 25, 2503-2512 (2015).
    • (2015) Curr. Biol , vol.25 , pp. 2503-2512
    • Challis, R.C.1
  • 306
  • 307
    • 79960013610 scopus 로고    scopus 로고
    • Loss of Bardet-Biedl syndrome protein-8 (BBS8) perturbs olfactory function, protein localization, and axon targeting
    • Tadenev, A. L. D. et al. Loss of Bardet-Biedl syndrome protein-8 (BBS8) perturbs olfactory function, protein localization, and axon targeting. Proc. Natl Acad. Sci. USA 108, 10320-10325 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 10320-10325
    • Tadenev, A.L.D.1
  • 308
    • 4444254983 scopus 로고    scopus 로고
    • Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse
    • Kulaga, H. M. et al. Loss of BBS proteins causes anosmia in humans and defects in olfactory cilia structure and function in the mouse. Nat. Genet. 36, 994-998 (2004).
    • (2004) Nat. Genet , vol.36 , pp. 994-998
    • Kulaga, H.M.1
  • 309
    • 35648960337 scopus 로고    scopus 로고
    • Hypomorphic CEP290/NPHP6 mutations result in anosmia caused by the selective loss of G proteins in cilia of olfactory sensory neurons
    • McEwen, D. P. et al. Hypomorphic CEP290/NPHP6 mutations result in anosmia caused by the selective loss of G proteins in cilia of olfactory sensory neurons. Proc. Natl Acad. Sci. USA 104, 15917-15922 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 15917-15922
    • McEwen, D.P.1
  • 310
    • 84868638709 scopus 로고    scopus 로고
    • Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model
    • McIntyre, J. C. et al. Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model. Nat. Med. 18, 1423-1428 (2012).
    • (2012) Nat. Med , vol.18 , pp. 1423-1428
    • McIntyre, J.C.1
  • 311
    • 84881183956 scopus 로고    scopus 로고
    • Goofy coordinates the acuity of olfactory signaling
    • Kaneko-Goto, T. et al. Goofy coordinates the acuity of olfactory signaling. J. Neurosci. 33, 12987-12996 (2013).
    • (2013) J. Neurosci , vol.33 , pp. 12987-12996
    • Kaneko-Goto, T.1
  • 312
    • 0015065143 scopus 로고
    • Centriole migration during regeneration and normal development of olfactory epithelium
    • Mulvaney, B. D. & Heist, H. E. Centriole migration during regeneration and normal development of olfactory epithelium. J. Ultrastruct. Res. 35, 274-281 (1971).
    • (1971) J. Ultrastruct. Res , vol.35 , pp. 274-281
    • Mulvaney, B.D.1    Heist, H.E.2
  • 313
    • 0022272137 scopus 로고
    • Genesis of cilia and microvilli of rat nasal epithelia during pre-natal development. I. Olfactory epithelium, qualitative studies
    • Menco, B. P. & Farbman, A. I. Genesis of cilia and microvilli of rat nasal epithelia during pre-natal development. I. Olfactory epithelium, qualitative studies. J. Cell Sci. 78, 283-310 (1985).
    • (1985) J. Cell Sci , vol.78 , pp. 283-310
    • Menco, B.P.1    Farbman, A.I.2
  • 314
    • 0016695443 scopus 로고
    • The development of the olfactory mucosa in the mouse: Electron microscopy
    • Cuschieri, A. & Bannister, L. H. The development of the olfactory mucosa in the mouse: electron microscopy. J. Anat. 119, 471-498 (1975).
    • (1975) J. Anat , vol.119 , pp. 471-498
    • Cuschieri, A.1    Bannister, L.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.