New neurons follow the flow of cerebrospinal fluid in the adult brain

Science

Volumn 311, Issue 5761, 2006, Pages 629-632

  Sawamoto, Kazunobu ^a,d   Wichterle, Hynek ^c   Gonzalez Perez, Oscar ^a   Cholfin, Jeremy A ^a,b   Yamada, Masayuki ^e   Spassky, Nathalie ^a   Murcia, Noel S ^f   Garcia Verdugo, Jose Manuel ^g   Marin, Oscar ^h   Rubenstein, John L R ^b   Tessier Lavigne, Marc ⁱ   Okano, Hideyuki ^d   Alvarez Buylla, Arturo ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e CENTRAL INSTITUTE FOR EXPERIMENTAL ANIMALS   (Japan)

^f CASE WESTERN RESERVE UNIVERSITY   (United States)

^g UNIVERSITY OF VALENCIA   (Spain)

^h MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

ⁱ GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; NEUROLOGY; POLARIZATION;

CEREBROSPINAL FLUID; CEREBROSPINAL FLUID (CSF); NEURONS;

BRAIN;

BIOLOGY;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MIGRATION; CEREBROSPINAL FLUID FLOW; CONTROLLED STUDY; EPENDYMA CELL; EPITHELIUM CELL; EUKARYOTIC FLAGELLUM; FLUOROSCOPY; IMAGE ANALYSIS; LATERAL BRAIN VENTRICLE; MOUSE; NERVE CELL; NEUROANATOMY; NEUROBLAST; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OLFACTORY BULB; PRIORITY JOURNAL; SUBVENTRICULAR ZONE;

ANIMALS; BRAIN TISSUE TRANSPLANTATION; CELL MOVEMENT; CELL POLARITY; CEREBRAL VENTRICLES; CEREBROSPINAL FLUID; CHOROID PLEXUS; CILIA; EPENDYMA; EPITHELIAL CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; NERVE TISSUE PROTEINS; NEURONS; OLFACTORY BULB; RECOMBINANT FUSION PROTEINS;

ANIMALIA; EUKARYOTA;

EID: 31944434903     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1119133     Document Type: Article

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23. We thank J. Aruga for the pAPTag2-Slit2 vector; G. Rougon for the PSA-NCAM antibody; C. Yaschine for editorial help; and A. Chedotal, Y. Uchiyama, T. Uemura, F. Murakami, S. Yonemura, and members of our laboratories for insightful discussions and encouragement. This work was supported by Bridgestone Corporation, a gift from Frances and John Bowes, and grants from NIH (NS 28478 and HD 32116), The Ministry of Education, Culture, Sports, Science and Technology, Japan Science and Technology Agency (CREST), Mitsui Life Social Welfare Foundation, and the Ministry of Health, Labor and Welfare.