Activation of NOTCH1 or NOTCH3 signaling skews human airway basal cell differentiation toward a secretory pathway

PLoS ONE

Volumn 10, Issue 2, 2015, Pages

  Gomi, Kazunori ^a   Arbelaez, Vanessa ^a   Crystal, Ronald G ^a   Walters, Matthew S ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; NOTCH RECEPTOR; NOTCH1 PROTEIN, HUMAN; NOTCH3 PROTEIN, HUMAN;

ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELLULAR DISTRIBUTION; CILIATED EPITHELIUM CELL; CONTROLLED STUDY; EPITHELIUM BASAL CELL; GENE; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; HUMAN; HUMAN CELL; LIGAND BINDING; NOTCH1 GENE; NOTCH2 GENE; NOTCH3 GENE; NOTCH4 GENE; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RESPIRATORY EPITHELIUM; SECRETORY CELL; SIGNAL TRANSDUCTION; CELL CULTURE; CYTOLOGY; METABOLISM; PROTEIN TERTIARY STRUCTURE; RESPIRATORY MUCOSA; SECRETORY PATHWAY;

LENTIVIRUS;

CELL DIFFERENTIATION; CELLS, CULTURED; HUMANS; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, NOTCH1; RECEPTOR, NOTCH3; RECEPTORS, NOTCH; RESPIRATORY MUCOSA; SECRETORY PATHWAY; SIGNAL TRANSDUCTION;

EID: 84923675686     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116507     Document Type: Article

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