Alzheimer's disease, normal-pressure hydrocephalus, and senescent changes in CSF circulatory physiology: A hypothesis

Lancet Neurology

Volumn 2, Issue 8, 2003, Pages 506-511

  Silverberg, Gerald D ^a   Mayo, Martha ^b   Saul, Thomas ^b   Rubenstein, Edward ^a   McGuire, Dawn ^b,c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Eunoe Inc   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID;

ALZHEIMER DISEASE; AMYLOID NEUROPATHY; BRAIN DEGENERATION; CEREBROSPINAL FLUID CIRCULATION DISORDER; CEREBROSPINAL FLUID DRAINAGE; CEREBROSPINAL FLUID FLOW; CEREBROSPINAL FLUID PRESSURE; CLINICAL FEATURE; CORRELATION ANALYSIS; HUMAN; HYPOTHESIS; NEUROPATHOLOGY; NEUROPHYSIOLOGY; NORMOTENSIVE HYDROCEPHALUS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; REVIEW; SENESCENCE; TISSUE DISTRIBUTION;

EID: 0038038284     PISSN: 14744422     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1474-4422(03)00487-3     Document Type: Note

References (63)

1. Del Bigio M.R., Cardoso E.R., Halliday W.C. Neuropathological changes in chronic adult hydrocephalus: cortical biopsies and autopsy findings. Can J Neurol Sci. 24:1997;121-126.
2. Savolainen S., Paljarvi L., Vapalahti M. Prevalence of Alzheimer's disease in patients investigated for presumed normal pressure hydrocephalus: a clinical and neuropathological study. Acta Neurochir (Wien). 141:1999;849-853.
3. Golomb J., Wisoff J., Miller D.C., et al. Alzheimer's disease comorbidity in normal pressure hydrocephalus: prevalence and shunt response. J Neurol Neurosurg Psychiatry. 68:2000;778-781.
4. Mirra S.S., Heyman A., McKeel D., et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD): part II-standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 41:1991;479-486.
5. Masserman J.H. Cerebrospinal fluid hydrodynamics IV: clinical experimental studies. Arch Neurol Psychiatry. 32:1934;524-553.
6. May C., Kaye J.A., Atack J.R., Schapiro M.B., Friedland R.P., Rapoport S.I. Cerebrospinal fluid production is reduced in healthy aging. Neurology. 40:1990;500-503.
7. Silverberg G.D., Heit G., Huhn S., et al. The cerebrospinal fluid production rate is reduced in dementia of the Alzheimer's type. Neurology. 57:2001;1763-1766.
8. Cutler R.W., Page L., Galicich J., Watters G.V. Formation and absorption of cerebrospinal fluid in man. Brain. 91:1968;707-720.
9. Rubin R.C., Henderson E.S., Ommaya A.K., Walker M.D., Rall D.P. The production of cerebrospinal fluid in man and its modification by acetazolamide. J Neurosurg. 25:1966;430-436.
10. Gideon P., Thomsen C., Stahlberg F., Henriksen O. Cerebrospinal fluid production and dynamics in normal aging: a MRI phase-mapping study. Acta Neurol Scand. 89:1994;362-366.
11. Fishman RA. Cerebrospinal fluid in diseases of the nervous system 2nd edn. Philadelphia: WB Saunders, 1992: 33-35 and 84-88.
12. Silverberg G.D., Huhn S., Jaffe R.A., et al. Downregulation of cerebrospinal fluid production in patients with chronic hydrocephalus. J Neurosurg. 97:2002;1271-1275.
13. Shuangshoti S., Netsky M.G. Human choroid plexus: morphologic and histochemical alterations with age. Am J Anat. 128:1970;73-95.
14. Preston J.E. Ageing choroid plexus-cerebrospinal fluid system. Microsc Res Tech. 52:2001;31-37.
15. Serot J.M., Bene M.C., Foliguet B., Faure G.C. Morphological alterations of the choroid plexus in late-onset Alzheimer's disease. Acta Neuropathol (Berl). 99:2000;105-108.
16. Madhavi C., Jacob M. Light and electron microscopic structure of choroid plexus in hydrocephalic guinea pig. Indian J Med Res. 101:1995;217-224.
17. Knuckey N.W., Preston J., Palm D., Epstein M.H., Johanson C. Hydrocephalus decreases chloride efflux from the choroid plexus epithelium. Brain Res. 618:1993;313-317.
18. Rubenstein E. Relationship of senescence of cerebrospinal fluid circulatory system to dementias of the aged. Lancet. 351:1998;283-285.
19. Monro O.R., Mackic J.B., Yamada S., et al. Substitution at codon 22 reduces clearance of Alzheimer's amyloid-beta peptide from the cerebrospinal fluid and prevents its transport from the central nervous system into the blood. Neurobiol Aging. 23:2002;405-412.
20. Zlokovic B.V. Can blood-brain barrier play a role in the development of cerebral amyloidosis and Alzheimer's disease pathology? Neurobiol Dis. 4:1997;23-26.
21. Mackic J.B., Weiss M.H., Miao W., et al. Cerebrovascular accumulation and increased blood-brain barrier permeability to circulating Alzheimer's amyloid beta peptide in aged squirrel monkey with cerebral amyloid angiopathy. J Neurochem. 70:1998;210-215.
22. Snowdon D.A., Greiner L.H., Mortimer J.A., Riley K.P., Greiner P.A., Markesbery W.R. Brain infarction and the clinical expression of Alzheimer's disease. JAMA. 277:1997;813-817.
23. Oldendorf W.H., Davson H. Brain extracellular space and the sink action of cerebrospinal fluid: measurement of rabbit brain extracellular space using sucrose labeled with carbon 14. Arch Neurol. 17:1967;196-205.
24. Rennels M.L., Blaumanis O.R., Grady P.A. Rapid solute transport throughout the brain via paravascular fluid pathways. Adv Neurol. 52:1990;431-439.
25. Johanson C. Ventricles and cerebrospinal fluid. Conn P.M. Neuroscience in medicine. 1995;179 Lippincott, Philadelphia.
26. Davson H., Oldendorf W.H. Symposium on membrane transport: transport in the central nervous system. Proc R Soc Med. 60:1967;326-329.
27. Ghersi-Egea J.F., Gorevic P.D., Ghiso J., Frangione B., Patlak C.S., Fenstermacher J.D. Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries. J Neurochem. 67:1996;880-883.
28. Hakim S., Adams R.D. The special clinical problem of symptomatic hydrocephalus with normal cerebrospinal fluid pressure: observations on cerebrospinal fluid hydrodynamics. J Neurol Sci. 2:1965;307-327.
29. Symon L., Dorch N.W.C., Stephens R.J. Pressure waves in so-called low-pressure hydrocephalus. Lancet. 2:1977;1291-1292.
30. Symon L., Dorch N.W.C. Use of long-term intracranial pressure measurement to assess hydrocephalic patients prior to shunt surgery. J Neurosurg. 42:1975;258-273.
31. Bret P., Guyolat J., Chazal J. Is normal pressure hydrocephalus a valid concept in 2002? A reappraisal in five questions and proposal for a new designation of the syndrome as "chronic hydrocephalus" J Neurol Neurosurg Psychiatry. 73:2002;9-12.
32. Albeck M.J., Skak C., Nielsen P.R., Olsen K.S., Borgesen S.E., Gjerris F. Age dependency of resistance to cerebrospinal fluid outflow. J Neurosurg. 89:1998;275-278.
33. Boon A.J., Tans J.T., Delwel E.J., et al. Does CSF outflow resistance predict the response to shunting in patients with normal pressure hydrocephalus? Acta Neurochir Suppl (Wien). 71:1998;331-333.
34. Bech R.A., Waldemar G., Gjerris F., Klinken L., Juhler M. Shunting effects in patients with idiopathic normal pressure hydrocephalus. Acta Neurochir (Wien). 141:1999;633-639.
35. Czosnyka M., Czosnyka Z.H., Whitfield P.C., Donovan T., Pickard J.D. Age dependence of cerebrospinal pressure-volume compensation in patients with hydrocephalus. J Neurosurg. 94:2001;482-486.
36. Hochwald G.M., Sahar A. Effect of spinal fluid pressure on cerebrospinal fluid formation. Exp Neurol. 32:1971;30-40.
37. Anttila T., Helkala E.L., Kivipelto M., et al. Midlife income, occupation, APOE status, and dementia: a population-based study. Neurology. 59:2002;887-893.
38. Selkoe D.J. Toward a comprehensive theory for Alzheimer's disease: hypothesis-Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein. Ann NY Acad Sci. 924:2000;17-25.
39. Geula C., Wu C.K., Saroff D., Lorenzo A., Yuan M., Yankner B.A. Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity. Nat Med. 4:1998;827-831.
40. Pirttila T., Mehta P.D., Soininen H., et al. Cerebrospinal fluid concentrations of soluble amyloid beta-protein and apolipoprotein E in patients with Alzheimer's disease: correlations with amyloid load in the brain. Arch Neurol. 53:1996;189-193.
41. Chaudury A.R., Gerecke K.M., Wyss J.M., Morgan D.G., Gordon M.N., Carroll S.L. Neuroregulin-1 and erbB4 immunoreactivity is associated with neuritic plaques in Alzheimer disease brain and in a transgenic model of Alzheimer disease. Neuropath Exp Neurol. 62:2003;42-54.
42. Lambert M.P., Barlow A.K., Chromy B.A., et al. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci USA. 95:1998;6448-6453.
43. Walsh D.M., Klyubin I., Fadeeva J.V., et al. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature. 416:2002;535-539.
44. Busciglio J., Lorenzo A., Yeh J., Yankner B.A. Beta-amyloid fibrils induce tau phosphorylation and loss of microtuble binding. Neuron. 14:1995;879-888.
45. Esler W.P., Stimson E.R., Ghilardi J.R., et al. In vitro growth of Alzheimer's disease beta-amyloid plaques displays first-order kinetics. Biochemistry. 35:1996;749-757.
46. Tyler J., Dawbarn D., Wilcock G.K., Allen S.J. Alpha and beta-secretase: profound changes in Alzheimer's disease. Biochem Biophys Res Commun. 299:2002;373-376.
47. Kalaria R.N., Premkumar D.R., Pax A.B., Cohen D.L., Lieberburg I. Production and increased detection of amyloid beta protein and amyloidogenic fragments in brain microvessels meningeal vessels and choroid plexus in Alzheimer's disease. Brain Res Mol Brain Res. 35:1996;58-68.
48. Hamano T., Yoshimura M., Yamazaki T., et al. Amyloid beta protein (A beta) accumulation in the leptomeninges during aging and in Alzheimer's Disease. J Neuropathol Exp Neurol. 56:1997;922-932.
49. Nilsson C., Stahlberg F., Gideon P., Thomsen C., Henriksen O. The nocturnal increase in human cerebrospinal fluid production is inhibited by a beta1-receptor antagonist. Am J Physiol. 267:1994;R1445-R1448.
50. Silverberg G.D., Levinthal E., Sullivan E.V., et al. Assessment of low-flow CSF drainage as a treatment for AD: results of a randomized pilot study. Neurology. 59:2002;1139-1145.
51. Mattis S. Mental status examination for organic mental syndrome in the elderly patient. Bellack R., Karasu B. Geriatric psychiatry. 1976;77-121 Grune and Stratton, New York.
52. Boon A.J., Tans J.T., Delwel E.J., et al. Dutch normal-pressure hydrocephalus study: randomized comparison of low- and medium-pressure shunts. J Neurosurg. 88:1998;490-495.
53. Blount J.P., Campbell J.A., Haines S.J. Complications in ventricular cerebrospinal fluid shunting. Neurosurg Clin North Am. 4:1993;633-656.
54. Mendez M.F., Catanzaro P., Doss R.C., Arguello R., Frey W.H. Seizures in Alzheimer's disease: clinicopathologic study. J Geriatr Psychiatry Neurol. 7:1994;230-233.
55. Risse S.C., Lampe T.H., Bird T.D., et al. Myoclonus, seizures, and paratonia in Alzheimer disease. Alzheimer Dis Assoc Disord. 4:1990;217-225.
56. Klinge P.M., Samii A., Muhlendyck A., et al. Cerebral hypoperfusion and delayed hippocampal response after induction of adult kaolin hydrocephalus. Stroke. 34:2003;193-199.
57. Tullberg M., Hultin L., Ekholm S., Mansson J.E., Fredman P., Wikkelso C. White matter changes in normal pressure hydrocephalus and Binswanger disease: specificity, predictive value and correlations to axonal degeneration and demyelination. Acta Neurol Scand. 105:2002;417-426.
58. Iddon J.L., Pickard J.D., Cross J.J., Griffiths P.D., Czosnyka M., Sahakian B.J. Specific patterns of cognitive impairment in patients with idiopathic normal pressure hydrocephalus and Alzheimer's disease: a pilot study. J Neurol Neurosurg Psychiatry. 67:1999;723-732.
59. Bannister C.M. A report of eight patients with low pressure hydrocephalus treated by CSF diversion with disappointing results. Acta Neurochir (Wien). 27:1972;11-15.
60. Raftopoulos C., Deleval J., Chaskis C., et al. Cognitive recovery in idiopathic normal pressure hydrocephalus: a prospective study. Neurosurgery. 35:1994;397-404.
61. Venneste J., Augustijn P., Dirven C., Tan W.F., Goedhart Z.D. Shunting normal-pressure hydrocephalus: do the benefits outweigh the risks? Neurology. 42:1992;54-59.
62. Thomsen A.M., Borgesen S.E., Bruhn P., Gjerris F. Prognosis of dementia in normal-pressure hydrocephalus after a shunt operation. Ann Neurol. 20:1986;304-310.
63. Savolainen S., Hurskainen H., Paljarvi L., Alafuzoff I., Vapalahti M. Five-year outcome of normal pressure hydrocephalus with or without a shunt: predictive value of the clinical signs, neuropsychological evaluation and infusion test. Acta Neurochir (Wien). 144:2002;515-523.