An olfactory cilia pattern in the mammalian nose ensures high sensitivity to odors

Current Biology

Volumn 25, Issue 19, 2015, Pages 2503-2512

  Challis, Rosemary C ^a   Tian, Huikai ^a   Wang, Jue ^a   He, Jiwei ^a   Jiang, Jianbo ^b   Chen, Xuanmao ^c   Yin, Wenbin ^a,d   Connelly, Timothy ^a   Ma, Limei ^e   Yu, C Ron ^e   Pluznick, Jennifer L ^f   Storm, Daniel R ^c   Huang, Liquan ^b,g   Zhao, Kai ^b   Ma, Minghong ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MONELL CHEMICAL SENSES CENTER   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d SHANDONG UNIVERSITY   (China)

^e STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

^f JOHNS HOPKINS UNIVERSITY   (United States)

^g ZHEJIANG UNIVERSITY   (China)

Author keywords

airflow; computational fluid dynamics model; odorant absorption; olfactory cilia; patch clamp; type III adenylyl cyclase

Indexed keywords

ADENYLATE CYCLASE; ADENYLATE CYCLASE 3; FRAGRANCE;

ANATOMIC MODEL; ANIMAL; BIOLOGICAL MODEL; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; MOUSE; NOSE; ODOR; OLFACTORY RECEPTOR NEURON; PHYSIOLOGY; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ADENYLYL CYCLASES; ANIMALS; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MODELS, ANATOMIC; MODELS, BIOLOGICAL; NOSE; ODORANTS; OLFACTORY RECEPTOR NEURONS; SIGNAL TRANSDUCTION; SMELL;

EID: 84943456951     PISSN: 09609822     EISSN: 18790445     Source Type: Journal    
DOI: 10.1016/j.cub.2015.07.065     Document Type: Article

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