Metazoan Nuclear Pores Provide a Scaffold for Poised Genes and Mediate Induced Enhancer-Promoter Contacts

Molecular Cell

Volumn 66, Issue 1, 2017, Pages 63-76.e6

  Pascual Garcia, Pau ^a   Debo, Brian ^a   Aleman, Jennifer R ^a   Talamas, Jessica A ^a   Lan, Yemin ^a   Nguyen, Nha H ^a   Won, Kyoung J ^a   Capelson, Maya ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

enhancer; genome architecture; looping; nuclear organization; nuclear pore complex; nucleoporin; Nup98; poised genes; transcription; transcriptional memory

Indexed keywords

ECDYSONE; NUCLEOPORIN; NUCLEOPORIN 98; CHROMATIN; DROSOPHILA PROTEIN; NUCLEAR PORE COMPLEX PROTEIN 98; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DROSOPHILA; ENHANCER REGION; GENE DISRUPTION; INSECT GENOME; INSULATOR ELEMENT; NONHUMAN; NUCLEAR PORE COMPLEX; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN BINDING; SILENT GENE; TRANSCRIPTION INITIATION; ANIMAL; BINDING SITE; CELL LINE; CHROMATIN; DROSOPHILA MELANOGASTER; DRUG EFFECTS; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; GENOTYPE; METABOLISM; MUTATION; PHENOTYPE; RNA INTERFERENCE; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BINDING SITES; CELL LINE; CHROMATIN; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; ECDYSONE; ENHANCER ELEMENTS, GENETIC; GENOTYPE; INSULATOR ELEMENTS; MUTATION; NUCLEAR PORE COMPLEX PROTEINS; PHENOTYPE; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; RNA INTERFERENCE; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION; TRANSFECTION;

EID: 85016510997     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2017.02.020     Document Type: Article

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