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Volumn 5, Issue JANUARY2016, 2016, Pages

Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes

Author keywords

[No Author keywords available]

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; EXPORTIN 1; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; LEPTOMYCIN B; NUP98 HOXA9 PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; RNA POLYMERASE II; TRANSCRIPTION FACTOR NANOG; TRICHOSTATIN A; UNCLASSIFIED DRUG; CELL RECEPTOR; CHROMATIN; EXPORTIN 1 PROTEIN; HOMEODOMAIN PROTEIN; KARYOPHERIN; NUCLEOPORIN; NUP98 PROTEIN, HUMAN; PROTEIN BINDING; TRANSCRIPTION FACTOR HOXA9;

EID: 84956963448     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.09540     Document Type: Article
Times cited : (49)

References (71)
  • 1
    • 0024654957 scopus 로고
    • Higher order chromosome structure is affected by cold-sensitive mutations in a schizosaccharomyces pombe gene crm1+ which encodes a 115- kD protein preferentially localized in the nucleus and its periphery
    • Adachi Y. 1989. Higher order chromosome structure is affected by cold-sensitive mutations in a schizosaccharomyces pombe gene crm1+ which encodes a 115- kD protein preferentially localized in the nucleus and its periphery. The Journal of Cell Biology 108:1195-1207. doi: 10.1083/jcb.108.4.1195.
    • (1989) The Journal of Cell Biology , vol.108 , pp. 1195-1207
    • Adachi, Y.1
  • 2
    • 33646417021 scopus 로고    scopus 로고
    • Trans-repressive effect of NUP98-PMX1 on PMX1-regulated c-FOS gene through recruitment of histone deacetylase 1 by FG repeats
    • Bai X-T. 2006. Trans-repressive effect of NUP98-PMX1 on PMX1-regulated c-FOS gene through recruitment of histone deacetylase 1 by FG repeats. Cancer Research 66:4584-4590. doi: 10.1158/0008-5472.CAN-05-3101.
    • (2006) Cancer Research , vol.66 , pp. 4584-4590
    • Bai, X.-T.1
  • 3
    • 16844370003 scopus 로고    scopus 로고
    • HOXA9 activates transcription of the gene encoding gp91Phox during myeloid differentiation
    • Bei L, Lu Y, Eklund EA. 2005. HOXA9 activates transcription of the gene encoding gp91Phox during myeloid differentiation. Journal of Biological Chemistry 280:12359-12370. doi: 10.1074/jbc.M408138200.
    • (2005) Journal of Biological Chemistry , vol.280 , pp. 12359-12370
    • Bei, L.1    Lu, Y.2    Eklund, E.A.3
  • 6
    • 0037142623 scopus 로고    scopus 로고
    • Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1
    • Calvo KR, Sykes DB, Pasillas MP, Kamps MP. 2002. Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1. Oncogene 21:4247-4256. doi: 10.1038/sj.onc.1205516.
    • (2002) Oncogene , vol.21 , pp. 4247-4256
    • Calvo, K.R.1    Sykes, D.B.2    Pasillas, M.P.3    Kamps, M.P.4
  • 7
    • 75749103380 scopus 로고    scopus 로고
    • Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes
    • Capelson M, Liang Y, Schulte R, Mair W, Wagner U, Hetzer MW. 2010. Chromatin-bound nuclear pore components regulate gene expression in higher eukaryotes. Cell 140:372-383. doi: 10.1016/j.cell.2009.12.054.
    • (2010) Cell , vol.140 , pp. 372-383
    • Capelson, M.1    Liang, Y.2    Schulte, R.3    Mair, W.4    Wagner, U.5    Hetzer, M.W.6
  • 9
    • 84922525901 scopus 로고    scopus 로고
    • A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias
    • Conway AE, Haldeman JM, Wechsler DS, Lavau CP. 2015. A critical role for CRM1 in regulating HOXA gene transcription in CALM-AF10 leukemias. Leukemia 29:423-432. doi: 10.1038/leu.2014.221.
    • (2015) Leukemia , vol.29 , pp. 423-432
    • Conway, A.E.1    Haldeman, J.M.2    Wechsler, D.S.3    Lavau, C.P.4
  • 10
    • 79952333966 scopus 로고    scopus 로고
    • Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK
    • Cross MK, Powers MA. 2011. Nup98 regulates bipolar spindle assembly through association with microtubules and opposition of MCAK. Molecular Biology of the Cell 22:661-672. doi: 10.1091/mbc.E10-06-0478.
    • (2011) Molecular Biology of the Cell , vol.22 , pp. 661-672
    • Cross, M.K.1    Powers, M.A.2
  • 11
    • 58049191558 scopus 로고    scopus 로고
    • Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation
    • Cui K, Zang C, Roh T-Y, Schones DE, Childs RW, Peng W, Zhao K. 2009. Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation. Cell Stem Cell 4:80-93. doi: 10.1016/j.stem.2008.11.011.
    • (2009) Cell Stem Cell , vol.4 , pp. 80-93
    • Cui, K.1    Zang, C.2    Roh, T.-Y.3    Schones, D.E.4    Childs, R.W.5    Peng, W.6    Zhao, K.7
  • 13
    • 0031053791 scopus 로고    scopus 로고
    • The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88
    • Fornerod M. 1997. The human homologue of yeast CRM1 is in a dynamic subcomplex with CAN/Nup214 and a novel nuclear pore component Nup88. The EMBO Journal 16:807-816. doi: 10.1093/emboj/16.4.807.
    • (1997) The EMBO Journal , vol.16 , pp. 807-816
    • Fornerod, M.1
  • 14
  • 15
    • 37549059945 scopus 로고    scopus 로고
    • Postintegrative gene silencing within the sleeping beauty transposition system
    • Garrison BS, Yant SR, Mikkelsen JG, Kay MA. 2007. Postintegrative gene silencing within the sleeping beauty transposition system. Molecular and Cellular Biology 27:8824-8833. doi: 10.1128/MCB.00498-07.
    • (2007) Molecular and Cellular Biology , vol.27 , pp. 8824-8833
    • Garrison, B.S.1    Yant, S.R.2    Mikkelsen, J.G.3    Kay, M.A.4
  • 17
    • 83455220210 scopus 로고    scopus 로고
    • NUP98 gene fusions and hematopoietic malignancies: Common themes and new biologic insights
    • Gough SM, Slape CI, Aplan PD. 2011. NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights. Blood 118:6247-6257. doi: 10.1182/blood-2011-07-328880.
    • (2011) Blood , vol.118 , pp. 6247-6257
    • Gough, S.M.1    Slape, C.I.2    Aplan, P.D.3
  • 18
    • 0036223543 scopus 로고    scopus 로고
    • Nup98 is a mobile nucleoporin with transcription-dependent dynamics
    • Griffis ER. 2002. Nup98 is a mobile nucleoporin with transcription-dependent dynamics. Molecular Biology of the Cell 13:1282-1297. doi: 10.1091/mbc.01-11-0538.
    • (2002) Molecular Biology of the Cell , vol.13 , pp. 1282-1297
    • Griffis, E.R.1
  • 19
    • 84865260520 scopus 로고    scopus 로고
    • The permeability of reconstituted nuclear pores provides direct evidence for the selective phase model
    • Hülsmann BB, Labokha AA, Görlich D. 2012. The permeability of reconstituted nuclear pores provides direct evidence for the selective phase model. Cell 150:738-751. doi: 10.1016/j.cell.2012.07.019.
    • (2012) Cell , vol.150 , pp. 738-751
    • Hülsmann, B.B.1    Labokha, A.A.2    Görlich, D.3
  • 20
    • 19944427423 scopus 로고    scopus 로고
    • Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model
    • Iwasaki M. 2005. Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model. Blood 105:784-793. doi: 10.1182/blood-2004-04-1508.
    • (2005) Blood , vol.105 , pp. 784-793
    • Iwasaki, M.1
  • 21
    • 84933556936 scopus 로고    scopus 로고
    • The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing
    • Jacinto FV, Benner C, Hetzer MW. 2015. The nucleoporin Nup153 regulates embryonic stem cell pluripotency through gene silencing. Genes & Development 29:1224-1238. doi: 10.1101/gad.260919.115.
    • (2015) Genes & Development , vol.29 , pp. 1224-1238
    • Jacinto, F.V.1    Benner, C.2    Hetzer, M.W.3
  • 22
    • 30744477013 scopus 로고    scopus 로고
    • The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation
    • Jeganathan KB, Malureanu L, van Deursen JM. 2005. The Rae1-Nup98 complex prevents aneuploidy by inhibiting securin degradation. Nature 438:1036-1039. doi: 10.1038/nature04221.
    • (2005) Nature , vol.438 , pp. 1036-1039
    • Jeganathan, K.B.1    Malureanu, L.2    Van Deursen, J.M.3
  • 23
    • 75749117571 scopus 로고    scopus 로고
    • Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm
    • Kalverda B, Pickersgill H, Shloma VV, Fornerod M. 2010. Nucleoporins directly stimulate expression of developmental and cell-cycle genes inside the nucleoplasm. Cell 140:360-371. doi: 10.1016/j.cell.2010.01.011.
    • (2010) Cell , vol.140 , pp. 360-371
    • Kalverda, B.1    Pickersgill, H.2    Shloma, V.V.3    Fornerod, M.4
  • 24
    • 47149108349 scopus 로고    scopus 로고
    • Histone deacetylase inhibition accelerates the early events of stem cell differentiation: Transcriptomic and epigenetic analysis
    • Karantzal E, Schulz H, Hummel O, Hubner N, Hatzopoulos AK, Kretsovali A. 2008. Histone deacetylase inhibition accelerates the early events of stem cell differentiation: transcriptomic and epigenetic analysis. Genome Biology 9:R65. doi: 10.1186/gb-2008-9-4-r65.
    • (2008) Genome Biology , vol.9
    • Karantzal, E.1    Schulz, H.2    Hummel, O.3    Hubner, N.4    Hatzopoulos, A.K.5    Kretsovali, A.6
  • 25
    • 0032927877 scopus 로고    scopus 로고
    • CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity
    • Kasper LH, Brindle PK, Schnabel CA, Pritchard CEJ, Cleary ML, van Deursen JMA. 1999. CREB binding protein interacts with nucleoporin-specific FG repeats that activate transcription and mediate NUP98-HOXA9 oncogenicity. Molecular and Cellular Biology 19:764-776. doi: 10.1128/MCB.19.1.764.
    • (1999) Molecular and Cellular Biology , vol.19 , pp. 764-776
    • Kasper, L.H.1    Brindle, P.K.2    Schnabel, C.A.3    Pritchard, C.4    Cleary, M.L.5    Van Deursen, J.6
  • 26
    • 1642367850 scopus 로고    scopus 로고
    • Transposition of the Tol2 element, an ac-like element from the japanese medaka fish oryzias latipes, in mouse embryonic stem cells
    • Kawakami K. 2004. Transposition of the Tol2 element, an ac-like element from the japanese medaka fish oryzias latipes, in mouse embryonic stem cells. Genetics 166:895-899. doi: 10.1534/genetics.166.2.895.
    • (2004) Genetics , vol.166 , pp. 895-899
    • Kawakami, K.1
  • 27
    • 44449177123 scopus 로고    scopus 로고
    • The organization of histone H3 modifications as revealed by a panel of specific monoclonal antibodies
    • Kimura H, Hayashi-Takanaka Y, Goto Y, Takizawa N, Nozaki N. 2008. The organization of histone H3 modifications as revealed by a panel of specific monoclonal antibodies. Cell Structure and Function 33:61-73. doi: 10.1247/csf.07035.
    • (2008) Cell Structure and Function , vol.33 , pp. 61-73
    • Kimura, H.1    Hayashi-Takanaka, Y.2    Goto, Y.3    Takizawa, N.4    Nozaki, N.5
  • 28
    • 0035253860 scopus 로고    scopus 로고
    • NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice
    • Kroon E. 2001. NUP98-HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice. The EMBO Journal 20:350-361. doi: 10.1093/emboj/20.3.350.
    • (2001) The EMBO Journal , vol.20 , pp. 350-361
    • Kroon, E.1
  • 30
    • 84859210032 scopus 로고    scopus 로고
    • Fast gapped-read alignment with bowtie 2
    • Langmead B, Salzberg SL. 2012. Fast gapped-read alignment with bowtie 2. Nature Methods 9:357-359. doi: 10.1038/nmeth.1923.
    • (2012) Nature Methods , vol.9 , pp. 357-359
    • Langmead, B.1    Salzberg, S.L.2
  • 33
    • 84875478639 scopus 로고    scopus 로고
    • A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory
    • Light WH, Freaney J, Sood V, Thompson A, D’Urso A, Horvath CM, Brickner JH, Misteli T. 2013. A conserved role for human Nup98 in altering chromatin structure and promoting epigenetic transcriptional memory. PLoS Biology 11:e1001524. doi: 10.1371/journal.pbio.1001524.
    • (2013) Plos Biology , vol.11
    • Light, W.H.1    Freaney, J.2    Sood, V.3    Thompson, A.4    D’Urso, A.5    Horvath, C.M.6    Brickner, J.H.7    Misteli, T.8
  • 34
    • 33745865934 scopus 로고    scopus 로고
    • Chromatin in pluripotent embryonic stem cells and differentiation
    • Meshorer E, Misteli T. 2006. Chromatin in pluripotent embryonic stem cells and differentiation. Nature Reviews Molecular Cell Biology 7:540-546. doi: 10.1038/nrm1938.
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , pp. 540-546
    • Meshorer, E.1    Misteli, T.2
  • 37
    • 0033118942 scopus 로고    scopus 로고
    • Nup153 is an M9-containing mobile nucleoporin with a novel ran-binding domain
    • Nakielny S. 1999. Nup153 is an M9-containing mobile nucleoporin with a novel ran-binding domain. The EMBO Journal 18:1982-1995. doi: 10.1093/emboj/18.7.1982.
    • (1999) The EMBO Journal , vol.18 , pp. 1982-1995
    • Nakielny, S.1
  • 39
    • 0036170533 scopus 로고    scopus 로고
    • Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of oct-3/4 in embryonic stem cells
    • Niwa H, Masui S, Chambers I, Smith AG, Miyazaki J.-i.. 2002. Phenotypic complementation establishes requirements for specific POU domain and generic transactivation function of oct-3/4 in embryonic stem cells. Molecular and Cellular Biology 22:1526-1536. doi: 10.1128/MCB.22.5.1526-1536.2002.
    • (2002) Molecular and Cellular Biology , vol.22 , pp. 1526-1536
    • Niwa, H.1    Masui, S.2    Chambers, I.3    Smith, A.G.4    Miyazaki, J.-I.5
  • 40
    • 80054678576 scopus 로고    scopus 로고
    • The classification of mRNA expression levels by the phosphorylation state of RNAPII CTD based on a combined genome-wide approach
    • Odawara J, Harada A, Yoshimi T, Maehara K, Tachibana T, Okada S, Akashi K, Ohkawa Y. 2011. The classification of mRNA expression levels by the phosphorylation state of RNAPII CTD based on a combined genome-wide approach. BMC Genomics 12:516. doi: 10.1186/1471-2164-12-516.
    • (2011) BMC Genomics , vol.12 , pp. 516
    • Odawara, J.1    Harada, A.2    Yoshimi, T.3    Maehara, K.4    Tachibana, T.5    Okada, S.6    Akashi, K.7    Ohkawa, Y.8
  • 41
    • 2942644252 scopus 로고    scopus 로고
    • A novel mechanism for regulating clonal propagation of mouse ES cells
    • Ogawa K, Matsui H, Ohtsuka S, Niwa H. 2004. A novel mechanism for regulating clonal propagation of mouse ES cells. Genes to Cells 9:471-477. doi: 10.1111/j.1356-9597.2004.00736.x.
    • (2004) Genes to Cells , vol.9 , pp. 471-477
    • Ogawa, K.1    Matsui, H.2    Ohtsuka, S.3    Niwa, H.4
  • 42
  • 43
    • 84878261274 scopus 로고    scopus 로고
    • Differential role for transcription factor Oct4 nucleocytoplasmic dynamics in somatic cell reprogramming and self-renewal of embryonic stem cells
    • Oka M, Moriyama T, Asally M, Kawakami K, Yoneda Y. 2013. Differential role for transcription factor Oct4 nucleocytoplasmic dynamics in somatic cell reprogramming and self-renewal of embryonic stem cells. Journal of Biological Chemistry 288:15085-15097. doi: 10.1074/jbc.M112.448837.
    • (2013) Journal of Biological Chemistry , vol.288 , pp. 15085-15097
    • Oka, M.1    Moriyama, T.2    Asally, M.3    Kawakami, K.4    Yoneda, Y.5
  • 44
    • 34548434716 scopus 로고    scopus 로고
    • Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells
    • Pan G, Tian S, Nie J, Yang C, Ruotti V, Wei H, Jonsdottir GA, Stewart R, Thomson JA. 2007. Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells. Cell Stem Cell 1:299-312. doi: 10.1016/j.stem.2007.08.003.
    • (2007) Cell Stem Cell , vol.1 , pp. 299-312
    • Pan, G.1    Tian, S.2    Nie, J.3    Yang, C.4    Ruotti, V.5    Wei, H.6    Jonsdottir, G.A.7    Stewart, R.8    Thomson, J.A.9
  • 45
    • 84915775241 scopus 로고    scopus 로고
    • Nucleoporin Nup98 associates with Trx/MLL and NSL histone- modifying complexes and regulates hox gene expression
    • Pascual-Garcia P, Jeong J, Capelson M. 2014. Nucleoporin Nup98 associates with Trx/MLL and NSL histone- modifying complexes and regulates hox gene expression. Cell Reports 9:1981. doi: 10.1016/j.celrep.2014.11.012.
    • (2014) Cell Reports , vol.9 , pp. 1981
    • Pascual-Garcia, P.1    Jeong, J.2    Capelson, M.3
  • 46
    • 33947727395 scopus 로고    scopus 로고
    • Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex
    • Patel SS, Belmont BJ, Sante JM, Rexach MF. 2007. Natively unfolded nucleoporins gate protein diffusion across the nuclear pore complex. Cell 129:83-96. doi: 10.1016/j.cell.2007.01.044.
    • (2007) Cell , vol.129 , pp. 83-96
    • Patel, S.S.1    Belmont, B.J.2    Sante, J.M.3    Rexach, M.F.4
  • 48
    • 0031046477 scopus 로고    scopus 로고
    • The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways
    • Powers MA. 1997. The vertebrate GLFG nucleoporin, Nup98, is an essential component of multiple RNA export pathways. The Journal of Cell Biology 136:241-250. doi: 10.1083/jcb.136.2.241.
    • (1997) The Journal of Cell Biology , vol.136 , pp. 241-250
    • Powers, M.A.1
  • 49
    • 7944236264 scopus 로고    scopus 로고
    • Mapping the dynamic organization of the nuclear pore complex inside single living cells
    • Rabut G, Doye V, Ellenberg J. 2004. Mapping the dynamic organization of the nuclear pore complex inside single living cells. Nature Cell Biology 6:1114-1121. doi: 10.1038/ncb1184.
    • (2004) Nature Cell Biology , vol.6 , pp. 1114-1121
    • Rabut, G.1    Doye, V.2    Ellenberg, J.3
  • 50
    • 0029021567 scopus 로고
    • The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
    • Radu A, Moore MS, Blobel G. 1995. The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex. Cell 81:215-222. doi: 10.1016/0092-8674(95)90331-3.
    • (1995) Cell , vol.81 , pp. 215-222
    • Radu, A.1    Moore, M.S.2    Blobel, G.3
  • 52
    • 84873675201 scopus 로고    scopus 로고
    • Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1
    • Roloff S, Spillner C, Kehlenbach RH. 2013. Several phenylalanine-glycine motives in the nucleoporin Nup214 are essential for binding of the nuclear export receptor CRM1. Journal of Biological Chemistry 288:3952-3963. doi:10.1074/jbc.M112.433243.
    • (2013) Journal of Biological Chemistry , vol.288 , pp. 3952-3963
    • Roloff, S.1    Spillner, C.2    Kehlenbach, R.H.3
  • 53
    • 84894275794 scopus 로고    scopus 로고
    • NUP98 fusion oncoproteins promote aneuploidy by attenuating the mitotic spindle checkpoint
    • Salsi V, Ferrari S, Gorello P, Fantini S, Chiavolelli F, Mecucci C, Zappavigna V. 2014. NUP98 fusion oncoproteins promote aneuploidy by attenuating the mitotic spindle checkpoint. Cancer Research 74:1079-1090. doi: 10.1158/0008-5472.CAN-13-0912.
    • (2014) Cancer Research , vol.74 , pp. 1079-1090
    • Salsi, V.1    Ferrari, S.2    Gorello, P.3    Fantini, S.4    Chiavolelli, F.5    Mecucci, C.6    Zappavigna, V.7
  • 54
    • 84922032902 scopus 로고    scopus 로고
    • Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity
    • Schmidt HB, Go¨ rlich D. 2015. Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity. eLife 4. doi: 10.7554/eLife.04251.
    • (2015) Elife , vol.4
    • Schmidt, H.B.1    Rlich, G.2
  • 55
    • 33845799903 scopus 로고    scopus 로고
    • Polycomb silencing mechanisms and the management of genomic programmes
    • Schwartz YB, Pirrotta V. 2007. Polycomb silencing mechanisms and the management of genomic programmes. Nature Reviews Genetics 8:9-22. doi: 10.1038/nrg1981.
    • (2007) Nature Reviews Genetics , vol.8 , pp. 9-22
    • Schwartz, Y.B.1    Pirrotta, V.2
  • 57
    • 33746167484 scopus 로고    scopus 로고
    • NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells
    • Takeda A. 2006. NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells. Cancer Research 66:6628-6637. doi: 10.1158/0008-5472.CAN-06-0458.
    • (2006) Cancer Research , vol.66 , pp. 6628-6637
    • Takeda, A.1
  • 58
    • 77952377310 scopus 로고    scopus 로고
    • Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins
    • Takeda A, Sarma NJ, Abdul-Nabi AM, Yaseen NR. 2010. Inhibition of CRM1-mediated nuclear export of transcription factors by leukemogenic NUP98 fusion proteins. Journal of Biological Chemistry 285:16248-16257. doi: 10.1074/jbc.M109.048785.
    • (2010) Journal of Biological Chemistry , vol.285 , pp. 16248-16257
    • Takeda, A.1    Sarma, N.J.2    Abdul-Nabi, A.M.3    Yaseen, N.R.4
  • 59
    • 34948839944 scopus 로고    scopus 로고
    • Facultative heterochromatin: Is there a distinctive molecular signature?
    • Trojer P, Reinberg D. 2007. Facultative heterochromatin: is there a distinctive molecular signature? Molecular Cell 28:1-13. doi: 10.1016/j.molcel.2007.09.011.
    • (2007) Molecular Cell , vol.28 , pp. 1-13
    • Trojer, P.1    Reinberg, D.2
  • 60
    • 33750433896 scopus 로고    scopus 로고
    • Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition
    • Urasaki A, Morvan G, Kawakami K. 2006. Functional dissection of the Tol2 transposable element identified the minimal cis-sequence and a highly repetitive sequence in the subterminal region essential for transposition. Genetics 174:639-649. doi: 10.1534/genetics.106.060244.
    • (2006) Genetics , vol.174 , pp. 639-649
    • Urasaki, A.1    Morvan, G.2    Kawakami, K.3
  • 61
    • 34347392874 scopus 로고    scopus 로고
    • NUP98-NSD1 links H3K36 methylation to hox-a gene activation and leukaemogenesis
    • Wang GG, Cai L, Pasillas MP, Kamps MP. 2007. NUP98-NSD1 links H3K36 methylation to hox-a gene activation and leukaemogenesis. Nature Cell Biology 9:804-812. doi: 10.1038/ncb1608.
    • (2007) Nature Cell Biology , vol.9 , pp. 804-812
    • Wang, G.G.1    Cai, L.2    Pasillas, M.P.3    Kamps, M.P.4
  • 63
    • 35848948403 scopus 로고    scopus 로고
    • Imaging hematopoietic precursor division in real time. Cell Stem Cell 1:541-554. Doi: 10.1016/j.Stem.2007.08.009 Xu S, Powers MA. 2009. Nuclear pore proteins and cancer
    • Wu M, Kwon HY, Rattis F, Blum J, Zhao C, Ashkenazi R, Jackson TL, Gaiano N, Oliver T, Reya T. 2007. Imaging hematopoietic precursor division in real time. Cell Stem Cell 1:541-554. doi: 10.1016/j.stem.2007.08.009 Xu S, Powers MA. 2009. Nuclear pore proteins and cancer. Seminars in Cell & Developmental Biology 20:620-630. doi: 10.1016/j.semcdb.2009.03.003.
    • (2007) Seminars in Cell & Developmental Biology , vol.20 , pp. 620-630
    • Wu, M.1    Kwon, H.Y.2    Rattis, F.3    Blum, J.4    Zhao, C.5    Ashkenazi, R.6    Jackson, T.L.7    Gaiano, N.8    Oliver, T.9    Reya, T.10
  • 64
    • 77951718965 scopus 로고    scopus 로고
    • Nup98-homeodomain fusions interact with endogenous Nup98 during interphase and localize to kinetochores and chromosome arms during mitosis
    • Xu S, Powers MA. 2010. Nup98-homeodomain fusions interact with endogenous Nup98 during interphase and localize to kinetochores and chromosome arms during mitosis. Molecular Biology of the Cell 21:1585-1596. doi: 10.1091/mbc.E09-07-0561.
    • (2010) Molecular Biology of the Cell , vol.21 , pp. 1585-1596
    • Xu, S.1    Powers, M.A.2
  • 65
    • 84876549786 scopus 로고    scopus 로고
    • In vivo analysis of human nucleoporin repeat domain interactions
    • Xu S, Powers MA. 2013. In vivo analysis of human nucleoporin repeat domain interactions. Molecular Biology of the Cell 24:1222-1231. doi: 10.1091/mbc.E12-08-0585.
    • (2013) Molecular Biology of the Cell , vol.24 , pp. 1222-1231
    • Xu, S.1    Powers, M.A.2
  • 67
    • 0034121993 scopus 로고    scopus 로고
    • Expression of the NUP98/HOXA9 fusion transcript in the blast crisis of philadelphia chromosome-positive chronic myelogenous leukaemia with t(7;11) (p15;p15)
    • Yamamoto K, Nakamura Y, Nakamura Y, Saito K, Furusawa S. 2000. Expression of the NUP98/HOXA9 fusion transcript in the blast crisis of philadelphia chromosome-positive chronic myelogenous leukaemia with t(7;11) (p15;p15). British Journal of Haematology 109:423-426. doi: 10.1046/j.1365-2141.2000.02003.x.
    • (2000) British Journal of Haematology , vol.109 , pp. 423-426
    • Yamamoto, K.1    Nakamura, Y.2    Nakamura, Y.3    Saito, K.4    Furusawa, S.5
  • 71
    • 0032888954 scopus 로고    scopus 로고
    • Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 rev
    • Zolotukhin AS, Felber BK. 1999. Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 rev. Journal of Virology 73:120-127.
    • (1999) Journal of Virology , vol.73 , pp. 120-127
    • Zolotukhin, A.S.1    Felber, B.K.2


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