-
1
-
-
84907888400
-
-
Cited 2016 Oct 28
-
WHO. The top 10 causes of death. 2014. Cited 2016 Oct 28. Available online: http://www. who. int/mediacentre/factsheets/fs310/en/
-
(2014)
The top 10 causes of death
-
-
-
2
-
-
85016274958
-
-
Asthma Fact Sheet N°307. Cited 2016 Oct 12
-
WHO. Asthma Fact Sheet N°307. 2013, Cited 2016 Oct 12. Available online: http://www. who. int/mediacentre/factsheets/fs307/en/
-
(2013)
-
-
-
3
-
-
85016324430
-
-
Cancer Fact Sheet N°297. Cited 2016 Oct 12
-
WHO. Cancer Fact Sheet N°297. 2015. Cited 2016 Oct 12. Available online: http://www. who. int/mediacentre/factsheets/fs297/en/
-
(2015)
-
-
-
4
-
-
33744792066
-
Proteases and their role in chronic inflammatory lung diseases
-
Bühling F, Groneberg D, Welte T. Proteases and their role in chronic inflammatory lung diseases. Curr Drug Targets 2006; 7: 751-9.
-
(2006)
Curr Drug Targets
, vol.7
, pp. 751-759
-
-
Bühling, F.1
Groneberg, D.2
Welte, T.3
-
5
-
-
0141928029
-
Chronic obstructive pulmonary disease: Molecular and cellular mechanisms
-
Barnes PJ, Shapiro SD, Pauwels RA. Chronic obstructive pulmonary disease: molecular and cellular mechanisms. Eur Respir J 2003; 22: 672-88.
-
(2003)
Eur Respir J
, vol.22
, pp. 672-688
-
-
Barnes, P.J.1
Shapiro, S.D.2
Pauwels, R.A.3
-
6
-
-
84976878698
-
Twenty years of the MEROPS database of proteolytic enzymes, their substrates and inhibitors
-
Rawlings ND, Barrett AJ, Finn RD. Twenty years of the MEROPS database of proteolytic enzymes, their substrates and inhibitors. Nucleic Acids Res 2016; 44: D343-D350.
-
(2016)
Nucleic Acids Res
, vol.44
, pp. D343-D350
-
-
Rawlings, N.D.1
Barrett, A.J.2
Finn, R.D.3
-
7
-
-
84859426282
-
MEROPS: The database of proteolytic enzymes, their substrates and inhibitors
-
Rawlings ND, Barrett AJ, Bateman A. MEROPS: the database of proteolytic enzymes, their substrates and inhibitors. Nucleic Acids Res 2012; 40: D343-50.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. D343-D350
-
-
Rawlings, N.D.1
Barrett, A.J.2
Bateman, A.3
-
8
-
-
1642534610
-
Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation
-
Aertgeerts K, Ye S, Tennant MG, et al. Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation. Protein Sci 2004; 13: 412-21.
-
(2004)
Protein Sci
, vol.13
, pp. 412-421
-
-
Aertgeerts, K.1
Ye, S.2
Tennant, M.G.3
-
9
-
-
0037219684
-
Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog
-
Rasmussen HB, Branner S, Wiberg FC, et al. Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog. Nat Struct Biol 2003; 10: 19-25.
-
(2003)
Nat Struct Biol
, vol.10
, pp. 19-25
-
-
Rasmussen, H.B.1
Branner, S.2
Wiberg, F.C.3
-
10
-
-
21244503095
-
Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha
-
Aertgeerts K, Levin I, Shi L, et al. Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein alpha. J Biol Chem 2005; 280: 19441-4.
-
(2005)
J Biol Chem
, vol.280
, pp. 19441-19444
-
-
Aertgeerts, K.1
Levin, I.2
Shi, L.3
-
11
-
-
0032563162
-
Prolyl Oligopeptidase: An Unusual B-Propeller Domain Regulates Proteolysis
-
Fülöp V Böcskei Z, Polgár L. Prolyl Oligopeptidase: An Unusual B-Propeller Domain Regulates Proteolysis. Cell 1998; 94: 161-70.
-
(1998)
Cell
, vol.94
, pp. 161-170
-
-
Fülöp, V.1
Böcskei, Z.2
Polgár, L.3
-
12
-
-
33845648469
-
Homology models of dipeptidyl peptidases 8 and 9 with a focus on loop predictions near the active site
-
Rummey C, Metz G. Homology models of dipeptidyl peptidases 8 and 9 with a focus on loop predictions near the active site. Proteins 2007; 66: 160-71.
-
(2007)
Proteins
, vol.66
, pp. 160-171
-
-
Rummey, C.1
Metz, G.2
-
13
-
-
0013986243
-
A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-betanaphthylamide
-
Hopsu-Havu VK, Glenner GG. A new dipeptide naphthylamidase hydrolyzing glycyl-prolyl-betanaphthylamide. Histochemie 1966; 7: 197-201.
-
(1966)
Histochemie
, vol.7
, pp. 197-201
-
-
Hopsu-Havu, V.K.1
Glenner, G.G.2
-
15
-
-
0026633296
-
Cloning and functional expression of the T cell activation antigen CD26
-
Tanaka T, Camerini D, Seed B, et al. Cloning and functional expression of the T cell activation antigen CD26. J Immunol 1992; 149: 481-6.
-
(1992)
J Immunol
, vol.149
, pp. 481-486
-
-
Tanaka, T.1
Camerini, D.2
Seed, B.3
-
17
-
-
84902552092
-
Soluble DPP4 originates in part from bone marrow cells and not from the kidney
-
Wang Z, Grigo C, Steinbeck J, et al. Soluble DPP4 originates in part from bone marrow cells and not from the kidney. Peptides 2014; 57: 109-17.
-
(2014)
Peptides
, vol.57
, pp. 109-117
-
-
Wang, Z.1
Grigo, C.2
Steinbeck, J.3
-
18
-
-
80052096595
-
Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome
-
Lamers D, Famulla S, Wronkowitz N, et al. Dipeptidyl peptidase 4 is a novel adipokine potentially linking obesity to the metabolic syndrome. Diabetes 2011; 60: 1917-25.
-
(2011)
Diabetes
, vol.60
, pp. 1917-1925
-
-
Lamers, D.1
Famulla, S.2
Wronkowitz, N.3
-
19
-
-
84876535013
-
Identification and validation of novel contraction-regulated myokines released from primary human skeletal muscle cells
-
Raschke S, Eckardt K, Bjørklund Holven K, et al. Identification and validation of novel contraction-regulated myokines released from primary human skeletal muscle cells. PLoS One 2013; 8: e62008.
-
(2013)
PLoS One
, vol.8
, pp. e62008
-
-
Raschke, S.1
Eckardt, K.2
Bjørklund Holven, K.3
-
20
-
-
84908242278
-
Shedding of dipeptidyl peptidase 4 is mediated by metalloproteases and up-regulated by hypoxia in human adipocytes and smooth muscle cells
-
Röhrborn D, Eckel J, Sell H. Shedding of dipeptidyl peptidase 4 is mediated by metalloproteases and up-regulated by hypoxia in human adipocytes and smooth muscle cells. FEBS Lett 2014; 588: 3870-7.
-
(2014)
FEBS Lett
, vol.588
, pp. 3870-3877
-
-
Röhrborn, D.1
Eckel, J.2
Sell, H.3
-
21
-
-
0028024630
-
Regional expression of epithelial dipeptidyl peptidase IV in the human intestines
-
Darmoul D, Voisin T, Couvineau A, et al. Regional expression of epithelial dipeptidyl peptidase IV in the human intestines. Biochem Biophys Res Commun 1994; 203: 1224-9.
-
(1994)
Biochem Biophys Res Commun
, vol.203
, pp. 1224-1229
-
-
Darmoul, D.1
Voisin, T.2
Couvineau, A.3
-
22
-
-
0026703489
-
Ultrastructural localization of dipeptidylpeptidase IV in the glomerulum of the rat kidney
-
Kettmann U, Humbel B, Holzhausen HJ. Ultrastructural localization of dipeptidylpeptidase IV in the glomerulum of the rat kidney. Acta Histochem 1992; 92: 225-7.
-
(1992)
Acta Histochem
, vol.92
, pp. 225-227
-
-
Kettmann, U.1
Humbel, B.2
Holzhausen, H.J.3
-
23
-
-
85016295416
-
-
Cited May 18
-
The Human Protein Atlas. Tissue expression of DPP4 -Summary. Cited 2016 May 18. Available online: http://www. proteinatlas. org/ENSG00000197635-DPP4/tissue#gene_information
-
(2016)
Tissue expression of DPP4 -Summary
-
-
-
24
-
-
79953320085
-
Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries
-
Matheeussen V, Baerts L, De Meyer G, et al. Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries. Biol Chem 2011; 392: 189-98.
-
(2011)
Biol Chem
, vol.392
, pp. 189-198
-
-
Matheeussen, V.1
Baerts, L.2
De Meyer, G.3
-
25
-
-
84862067258
-
Human Th17 cells express high levels of enzymatically active dipeptidylpeptidase IV (CD26)
-
Bengsch B, Seigel B, Flecken T, et al. Human Th17 cells express high levels of enzymatically active dipeptidylpeptidase IV (CD26). J Immunol 2012; 188: 5438-47.
-
(2012)
J Immunol
, vol.188
, pp. 5438-5447
-
-
Bengsch, B.1
Seigel, B.2
Flecken, T.3
-
26
-
-
0024331402
-
1F7, a novel cell surface molecule, involved in helper function of CD4 cells
-
Morimoto C, Torimoto Y, Levinson G, et al. 1F7, a novel cell surface molecule, involved in helper function of CD4 cells. J Immunol 1989; 143: 3430-9.
-
(1989)
J Immunol
, vol.143
, pp. 3430-3439
-
-
Morimoto, C.1
Torimoto, Y.2
Levinson, G.3
-
27
-
-
84938497115
-
The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis
-
Waumans Y, Baerts L, Kehoe K, et al. The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis. Front Immunol 2015; 6: 387.
-
(2015)
Front Immunol
, vol.6
, pp. 387
-
-
Waumans, Y.1
Baerts, L.2
Kehoe, K.3
-
28
-
-
84974808180
-
Cut to the chase: A review of CD26/dipeptidyl peptidase-4's (DPP4) entanglement in the immune system
-
Klemann C, Wagner L, Stephan M, et al. Cut to the chase: a review of CD26/dipeptidyl peptidase-4's (DPP4) entanglement in the immune system. Clin Exp Immunol 2016; 185: 1-21.
-
(2016)
Clin Exp Immunol
, vol.185
, pp. 1-21
-
-
Klemann, C.1
Wagner, L.2
Stephan, M.3
-
29
-
-
0027215348
-
Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
-
Mentlein R, Gallwitz B, Schmidt WE. Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum. Eur J Biochem 1993; 214: 829-35.
-
(1993)
Eur J Biochem
, vol.214
, pp. 829-835
-
-
Mentlein, R.1
Gallwitz, B.2
Schmidt, W.E.3
-
30
-
-
0027494070
-
Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV
-
Mentlein R, Dahms P, Grandt D, et al. Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV. Regul Pept 1993; 49: 133-44.
-
(1993)
Regul Pept
, vol.49
, pp. 133-144
-
-
Mentlein, R.1
Dahms, P.2
Grandt, D.3
-
31
-
-
0035895070
-
Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties
-
Proost P. Amino-terminal truncation of CXCR3 agonists impairs receptor signaling and lymphocyte chemotaxis, while preserving antiangiogenic properties. Blood 2001; 98: 3554-61.
-
(2001)
Blood
, vol.98
, pp. 3554-3561
-
-
Proost, P.1
-
33
-
-
0030683638
-
Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1
-
Crump MP, Gong JH, Loetscher P, et al. Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1. EMBO J 1997; 16: 6996-7007.
-
(1997)
EMBO J
, vol.16
, pp. 6996-7007
-
-
Crump, M.P.1
Gong, J.H.2
Loetscher, P.3
-
34
-
-
0037787851
-
Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV
-
Lambeir AM, Durinx C, Scharpé S, et al. Dipeptidyl-Peptidase IV from Bench to Bedside: An Update on Structural Properties, Functions, and Clinical Aspects of the Enzyme DPP IV. Crit Rev Clin Lab Sci 2003; 40: 209-94.
-
(2003)
Crit Rev Clin Lab Sci
, vol.40
, pp. 209-294
-
-
Lambeir, A.M.1
Durinx, C.2
Scharpé, S.3
-
35
-
-
0028354779
-
Binding of adenosine deaminase to the lymphocyte surface via CD26
-
De Meester I, Vanham G, Kestens L, et al. Binding of adenosine deaminase to the lymphocyte surface via CD26. Eur J Immunol 1994; 24: 566-70.
-
(1994)
Eur J Immunol
, vol.24
, pp. 566-570
-
-
De Meester, I.1
Vanham, G.2
Kestens, L.3
-
36
-
-
0027201145
-
Direct association of adenosine deaminase with a T cell activation antigen, CD26
-
Kameoka J, Tanaka T, Nojima Y, et al. Direct association of adenosine deaminase with a T cell activation antigen, CD26. Science 1993; 261: 466-9.
-
(1993)
Science
, vol.261
, pp. 466-469
-
-
Kameoka, J.1
Tanaka, T.2
Nojima, Y.3
-
37
-
-
4644325083
-
CD26 up-regulates expression of CD86 on antigen-presenting cells by means of caveolin-1
-
Ohnuma K, Yamochi T, Uchiyama M, et al. CD26 up-regulates expression of CD86 on antigen-presenting cells by means of caveolin-1. Proc Natl Acad Sci U S A 2004; 101: 14186-91.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 14186-14191
-
-
Ohnuma, K.1
Yamochi, T.2
Uchiyama, M.3
-
38
-
-
0034682458
-
Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor Ikushima H, Munakata Y, Ishii T, et al
-
Ikushima H, Munakata Y, Ishii T, et al. Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor Ikushima H, Munakata Y, Ishii T, et al. Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor receptor contributes to T cell activation. Proc Natl Acad Sci U S A 2000; 97: 8439-44.
-
(2000)
Internalization of CD26 by mannose 6-phosphate/insulin-like growth factor receptor contributes to T cell activation. Proc Natl Acad Sci U S A
, vol.97
, pp. 8439-8444
-
-
Ikushima, H.1
Munakata, Y.2
Ishii, T.3
-
39
-
-
0036346299
-
Soluble CD26/ dipeptidyl peptidase IV enhances transendothelial migration via its interaction with mannose 6-phosphate/ insulin-like growth factor II receptor
-
Ikushima H, Munakata Y, Iwata S, et al. Soluble CD26/ dipeptidyl peptidase IV enhances transendothelial migration via its interaction with mannose 6-phosphate/ insulin-like growth factor II receptor. Cell Immunol 2002; 215: 106-10.
-
(2002)
Cell Immunol
, vol.215
, pp. 106-110
-
-
Ikushima, H.1
Munakata, Y.2
Iwata, S.3
-
40
-
-
38849093208
-
Dipeptidyl peptidase IV inhibition downregulates Na+ - H+ exchanger NHE3 in rat renal proximal tubule
-
Girardi ACC, Fukuda LE, Rossoni LV, et al. Dipeptidyl peptidase IV inhibition downregulates Na+ - H+ exchanger NHE3 in rat renal proximal tubule. Am J Physiol Renal Physiol 2008; 294: F414-22.
-
(2008)
Am J Physiol Renal Physiol
, vol.294
, pp. F414-F422
-
-
Girardi, A.C.C.1
Fukuda, L.E.2
Rossoni, L.V.3
-
41
-
-
0043092068
-
A novel consensus motif in fibronectin mediates dipeptidyl peptidase IV adhesion and metastasis
-
Cheng H-C, Abdel-Ghany M, Pauli BU. A novel consensus motif in fibronectin mediates dipeptidyl peptidase IV adhesion and metastasis. J Biol Chem 2003; 278: 24600-7.
-
(2003)
J Biol Chem
, vol.278
, pp. 24600-24607
-
-
Cheng, H.-C.1
Abdel-Ghany, M.2
Pauli, B.U.3
-
42
-
-
0029616309
-
The cysteinerich region of dipeptidyl peptidase IV (CD 26) is the collagen-binding site
-
Löster K, Zeilinger K, Schuppan D, et al. The cysteinerich region of dipeptidyl peptidase IV (CD 26) is the collagen-binding site. Biochem Biophys Res Commun 1995; 217: 341-8.
-
(1995)
Biochem Biophys Res Commun
, vol.217
, pp. 341-348
-
-
Löster, K.1
Zeilinger, K.2
Schuppan, D.3
-
43
-
-
0035723325
-
CD26: A multifunctional integral membrane and secreted protein of activated lymphocytes
-
Gorrell MD, Gysbers V, McCaughan GW. CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes. Scand J Immunol 2001; 54: 249-64.
-
(2001)
Scand J Immunol
, vol.54
, pp. 249-264
-
-
Gorrell, M.D.1
Gysbers, V.2
McCaughan, G.W.3
-
44
-
-
23044510616
-
CD26 Regulates p38 Mitogen-Activated Protein Kinase-Dependent Phosphorylation of Integrin B1, Adhesion to Extracellular Matrix, and Tumorigenicity of T-anaplastic large cell lymphoma Karpas 299
-
Sato T, Yamochi T, Yamochi T, et al. CD26 Regulates p38 Mitogen-Activated Protein Kinase-Dependent Phosphorylation of Integrin B1, Adhesion to Extracellular Matrix, and Tumorigenicity of T-anaplastic large cell lymphoma Karpas 299. Cancer Res 2005; 65: 6950-6.
-
(2005)
Cancer Res
, vol.65
, pp. 6950-6956
-
-
Sato, T.1
Yamochi, T.2
Yamochi, T.3
-
45
-
-
0033780088
-
Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8
-
Abbott CA, Yu DM, Woollatt E, et al. Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8. Eur J Biochem 2000; 267: 6140-50.
-
(2000)
Eur J Biochem
, vol.267
, pp. 6140-6150
-
-
Abbott, C.A.1
Yu, D.M.2
Woollatt, E.3
-
46
-
-
0037121086
-
Identification and characterization of human DPP9, a novel homologue of dipeptidyl peptidase IV
-
Olsen C, Wagtmann N. Identification and characterization of human DPP9, a novel homologue of dipeptidyl peptidase IV. Gene 2002; 299: 185-93.
-
(2002)
Gene
, vol.299
, pp. 185-193
-
-
Olsen, C.1
Wagtmann, N.2
-
47
-
-
84906934346
-
The amino terminus extension in the long dipeptidyl peptidase 9 isoform contains a nuclear localization signal targeting the active peptidase to the nucleus
-
Justa-Schuch D, Möller U, Geiss-Friedlander R The amino terminus extension in the long dipeptidyl peptidase 9 isoform contains a nuclear localization signal targeting the active peptidase to the nucleus. Cell Mol Life Sci 2014; 71: 3611-26.
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 3611-3626
-
-
Justa-Schuch, D.1
Möller, U.2
Geiss-Friedlander, R.3
-
48
-
-
84892403636
-
Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality
-
Gall MG, Chen Y, Vieira de Ribeiro AJ, et al. Targeted inactivation of dipeptidyl peptidase 9 enzymatic activity causes mouse neonate lethality. PLoS One 2013; 8: e78378.
-
(2013)
PLoS One
, vol.8
, pp. e78378
-
-
Gall, M.G.1
Chen, Y.2
Vieira de Ribeiro, A.J.3
-
49
-
-
84959457702
-
Dipeptidyl peptidase 9 enzymatic activity influences the expression of neonatal metabolic genes
-
Chen Y, Gall MG, Zhang H, et al. Dipeptidyl peptidase 9 enzymatic activity influences the expression of neonatal metabolic genes. Exp Cell Res 2016; 342: 72-82.
-
(2016)
Exp Cell Res
, vol.342
, pp. 72-82
-
-
Chen, Y.1
Gall, M.G.2
Zhang, H.3
-
50
-
-
33744814340
-
Dipeptidyl peptidases 8 and 9: Specificity and molecular characterization compared with dipeptidyl peptidase IV
-
Bjelke JR, Christensen J, Nielsen PF, et al. Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV. Biochem J 2006; 396: 391-9.
-
(2006)
Biochem J
, vol.396
, pp. 391-399
-
-
Bjelke, J.R.1
Christensen, J.2
Nielsen, P.F.3
-
51
-
-
70350444734
-
The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides
-
Geiss-Friedlander R Parmentier N, Möller U, et al. The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides. J Biol Chem 2009; 284: 27211-9.
-
(2009)
J Biol Chem
, vol.284
, pp. 27211-27219
-
-
Geiss-Friedlander, R.1
Parmentier, N.2
Möller, U.3
-
52
-
-
84938784378
-
Inhibition of dipeptidyl peptidase 8/9 impairs preadipocyte differentiation
-
Han R Wang X, Bachovchin W, et al. Inhibition of dipeptidyl peptidase 8/9 impairs preadipocyte differentiation. Sci Rep 2015; 5: 12348.
-
(2015)
Sci Rep
, vol.5
, pp. 12348
-
-
Han, R.1
Wang, X.2
Bachovchin, W.3
-
53
-
-
84876284612
-
Dipeptidyl peptidases in atherosclerosis: Expression and role in macrophage differentiation, activation and apoptosis
-
Matheeussen V, Waumans Y, Martinet W, et al. Dipeptidyl peptidases in atherosclerosis: expression and role in macrophage differentiation, activation and apoptosis. Basic Res Cardiol 2013; 108: 350.
-
(2013)
Basic Res Cardiol
, vol.108
, pp. 350
-
-
Matheeussen, V.1
Waumans, Y.2
Martinet, W.3
-
54
-
-
84958058029
-
The Dipeptidyl Peptidases 4, 8, and 9 in Mouse Monocytes and Macrophages: DPP8/9 Inhibition Attenuates M1 Macrophage Activation in Mice
-
Waumans Y, Vliegen G, Maes L, et al. The Dipeptidyl Peptidases 4, 8, and 9 in Mouse Monocytes and Macrophages: DPP8/9 Inhibition Attenuates M1 Macrophage Activation in Mice. Inflammation 2016; 39: 413-24.
-
(2016)
Inflammation
, vol.39
, pp. 413-424
-
-
Waumans, Y.1
Vliegen, G.2
Maes, L.3
-
55
-
-
84919915612
-
Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin
-
Zhang H, Chen Y, Wadham C, et al. Dipeptidyl peptidase 9 subcellular localization and a role in cell adhesion involving focal adhesion kinase and paxillin. Biochim Biophys Acta 2015; 1853: 470-80.
-
(2015)
Biochim Biophys Acta
, vol.1853
, pp. 470-480
-
-
Zhang, H.1
Chen, Y.2
Wadham, C.3
-
56
-
-
79960661852
-
A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling
-
Yao TW, Kim WS, Yu DM, et al. A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling. Mol Cancer Res. 2011; 9: 948-59.
-
(2011)
Mol Cancer Res
, vol.9
, pp. 948-959
-
-
Yao, T.W.1
Kim, W.S.2
Yu, D.M.3
-
57
-
-
84871782137
-
A novel SUMO1-specific interacting motif in Dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation
-
Pilla E, Möller U, Sauer G, et al. A novel SUMO1-specific interacting motif in Dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation. J Biol Chem 2012; 287: 44320-9.
-
(2012)
J Biol Chem
, vol.287
, pp. 44320-44329
-
-
Pilla, E.1
Möller, U.2
Sauer, G.3
-
58
-
-
84989184719
-
DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk
-
Justa-Schuch D, Silva-Garcia M, Pilla E, et al. DPP9 is a novel component of the N-end rule pathway targeting the tyrosine kinase Syk. Elife 2016; 5. pii: e16370.
-
(2016)
Elife
, vol.5
, pp. e16370
-
-
Justa-Schuch, D.1
Silva-Garcia, M.2
Pilla, E.3
-
59
-
-
70449698442
-
The In Vivo Expression of Dipeptidyl Peptidases 8 and 9
-
Yu DM, Ajami K, Gall MG, et al. The In Vivo Expression of Dipeptidyl Peptidases 8 and 9. J Histochem Cytochem 2009; 57: 1025-40.
-
(2009)
J Histochem Cytochem
, vol.57
, pp. 1025-1040
-
-
Yu, D.M.1
Ajami, K.2
Gall, M.G.3
-
60
-
-
84881103262
-
DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues
-
Harstad EB, Rosenblum JS, Gorrell MD, et al. DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues. Regul Pept 2013; 186: 26-35.
-
(2013)
Regul Pept
, vol.186
, pp. 26-35
-
-
Harstad, E.B.1
Rosenblum, J.S.2
Gorrell, M.D.3
-
61
-
-
42649117199
-
Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes
-
Dubois V, Lambeir AM, Van der Veken P, et al. Purification and characterization of dipeptidyl peptidase IV-like enzymes from bovine testes. Front Biosci 2008; 13: 3558-68.
-
(2008)
Front Biosci
, vol.13
, pp. 3558-3568
-
-
Dubois, V.1
Lambeir, A.M.2
Van der Veken, P.3
-
62
-
-
0022847015
-
Differential expression of cell surface antigens and glial fibrillary acidic protein in human astrocytoma subsets
-
Rettig WJ, Chesa PG, Beresford HR, et al. Differential expression of cell surface antigens and glial fibrillary acidic protein in human astrocytoma subsets. Cancer Res 1986; 46: 6406-12.
-
(1986)
Cancer Res
, vol.46
, pp. 6406-6412
-
-
Rettig, W.J.1
Chesa, P.G.2
Beresford, H.R.3
-
63
-
-
32644446428
-
Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein
-
Lee KN, Jackson KW, Christiansen VJ, et al. Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein. Blood 2006; 107: 1397-404.
-
(2006)
Blood
, vol.107
, pp. 1397-1404
-
-
Lee, K.N.1
Jackson, K.W.2
Christiansen, V.J.3
-
64
-
-
33344475312
-
Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly(2)-Pro(1)-cleaving specificity
-
Edosada CY, Quan C, Tran T, et al. Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly(2)-Pro(1)-cleaving specificity. FEBS Lett 2006; 580: 1581-6.
-
(2006)
FEBS Lett
, vol.580
, pp. 1581-1586
-
-
Edosada, C.Y.1
Quan, C.2
Tran, T.3
-
65
-
-
38349169216
-
Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites
-
Aggarwal S, Brennen WN, Kole TP, et al. Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites. Biochemistry 2008; 47: 1076-86.
-
(2008)
Biochemistry
, vol.47
, pp. 1076-1086
-
-
Aggarwal, S.1
Brennen, W.N.2
Kole, T.P.3
-
66
-
-
2342447229
-
A novel plasma proteinase potentiates a2-antiplasmin inhibition of fibrin digestion
-
Lee KN, Jackson KW, Christiansen VJ, et al. A novel plasma proteinase potentiates a2-antiplasmin inhibition of fibrin digestion. Blood 2004; 103: 3783-8.
-
(2004)
Blood
, vol.103
, pp. 3783-3788
-
-
Lee, K.N.1
Jackson, K.W.2
Christiansen, V.J.3
-
67
-
-
33846018363
-
Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV
-
Christiansen VJ, Jackson KW, Lee KN, et al. Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV. Arch Biochem Biophys 2007; 457: 177-86.
-
(2007)
Arch Biochem Biophys
, vol.457
, pp. 177-186
-
-
Christiansen, V.J.1
Jackson, K.W.2
Lee, K.N.3
-
68
-
-
79953729051
-
Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-a
-
Keane FM, Nadvi NA, Yao TW, et al. Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-a. FEBS J 2011; 278: 1316-32.
-
(2011)
FEBS J
, vol.278
, pp. 1316-1332
-
-
Keane, F.M.1
Nadvi, N.A.2
Yao, T.W.3
-
69
-
-
0025083528
-
Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers
-
Garin-Chesa P, Old LJ, Rettig WJ. Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers. Proc Natl Acad Sci U S A 1990; 87: 7235-9.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 7235-7239
-
-
Garin-Chesa, P.1
Old, L.J.2
Rettig, W.J.3
-
70
-
-
70350542778
-
Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes
-
Bauer S, Jendro MC, Wadle A, et al. Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes. Arthritis Res Ther 2006; 8: R171.
-
(2006)
Arthritis Res Ther
, vol.8
, pp. R171
-
-
Bauer, S.1
Jendro, M.C.2
Wadle, A.3
-
71
-
-
80755172656
-
Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata
-
Brokopp CE, Schoenauer R, Richards P, et al. Fibroblast activation protein is induced by inflammation and degrades type I collagen in thin-cap fibroatheromata. Eur Heart J 2011; 32: 2713-22.
-
(2011)
Eur Heart J
, vol.32
, pp. 2713-2722
-
-
Brokopp, C.E.1
Schoenauer, R.2
Richards, P.3
-
72
-
-
0033034717
-
Fibroblast activation protein: A cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis
-
Levy MT, McCaughan GW, Abbott CA, et al. Fibroblast activation protein: A cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis. Hepatology 1999; 29: 1768-78.
-
(1999)
Hepatology
, vol.29
, pp. 1768-1778
-
-
Levy, M.T.1
McCaughan, G.W.2
Abbott, C.A.3
-
73
-
-
0035060205
-
Expression of the fibroblast activation protein during mouse embryo development
-
Niedermeyer J, Garin-Chesa P, Kriz M, et al. Expression of the fibroblast activation protein during mouse embryo development. Int J Dev Biol 2001; 45: 445-7.
-
(2001)
Int J Dev Biol
, vol.45
, pp. 445-447
-
-
Niedermeyer, J.1
Garin-Chesa, P.2
Kriz, M.3
-
74
-
-
84890386346
-
Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs
-
Keane FM, Yao TW, Seelk S, et al. Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs. FEBS Open Bio 2013; 4: 43-54.
-
(2013)
FEBS Open Bio
, vol.4
, pp. 43-54
-
-
Keane, F.M.1
Yao, T.W.2
Seelk, S.3
-
75
-
-
84880687861
-
Depletion of stromal cells expressing fibroblast activation protein-A from skeletal muscle and bone marrow results in cachexia and anemia
-
Roberts EW, Deonarine A, Jones JO, t al. Depletion of stromal cells expressing fibroblast activation protein-A from skeletal muscle and bone marrow results in cachexia and anemia. J Exp Med 2013; 210: 1137-51.
-
(2013)
J Exp Med
, vol.210
, pp. 1137-1151
-
-
Roberts, E.W.1
Deonarine, A.2
Jones, J.O.3
-
76
-
-
23744458987
-
Characterization of cancer stroma markers: In silico analysis of an mRNA expression database for fibroblast activation protein and endosialin
-
Dolznig H, Schweifer N, Puri C, et al. Characterization of cancer stroma markers: in silico analysis of an mRNA expression database for fibroblast activation protein and endosialin. Cancer Immun 2005; 5: 10.
-
(2005)
Cancer Immun
, vol.5
, pp. 10
-
-
Dolznig, H.1
Schweifer, N.2
Puri, C.3
-
77
-
-
0033967471
-
Targeted disruption of mouse fibroblast activation protein
-
Niedermeyer J, Kriz M, Hilberg F, et al. Targeted disruption of mouse fibroblast activation protein. Mol Cell Biol 2000; 20: 1089-94.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 1089-1094
-
-
Niedermeyer, J.1
Kriz, M.2
Hilberg, F.3
-
78
-
-
0005429990
-
Cell-surface glycoproteins of human sarcomas: Differential expression in normal and malignant tissues and cultured cells
-
Rettig WJ, Garin-Chesa P, Beresford HR et al. Cell-surface glycoproteins of human sarcomas: differential expression in normal and malignant tissues and cultured cells. Proc Natl Acad Sci U S A 1988; 85: 3110-4.
-
(1988)
Proc Natl Acad Sci U S A
, vol.85
, pp. 3110-3114
-
-
Rettig, W.J.1
Garin-Chesa, P.2
Beresford, H.R.3
-
79
-
-
0035915797
-
Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast
-
Ariga N, Sato E, Ohuchi N, et al Stromal expression of fibroblast activation protein/seprase, a cell membrane serine proteinase and gelatinase, is associated with longer survival in patients with invasive ductal carcinoma of breast. Int J Cancer 2001; 95: 67-72.
-
(2001)
Int J Cancer
, vol.95
, pp. 67-72
-
-
Ariga, N.1
Sato, E.2
Ohuchi, N.3
-
80
-
-
84856934228
-
Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy
-
Brennen WN, Isaacs JT, Denmeade SR. Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy. Mol Cancer Ther 2012; 11: 257-66.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 257-266
-
-
Brennen, W.N.1
Isaacs, J.T.2
Denmeade, S.R.3
-
81
-
-
84880656055
-
Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
-
Tran E, Chinnasamy D, Yu Z, et al. Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia. J Exp Med 2013; 210: 1125-35.
-
(2013)
J Exp Med
, vol.210
, pp. 1125-1135
-
-
Tran, E.1
Chinnasamy, D.2
Yu, Z.3
-
82
-
-
84996565577
-
Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity
-
Wang LC, Lo A, Scholler J, et al. Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity. Cancer Immunol Res 2014; 2: 154-66.
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 154-166
-
-
Wang, L.C.1
Lo, A.2
Scholler, J.3
-
83
-
-
72849125358
-
Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice
-
Santos AM, Jung J, Aziz N, et al. Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. J Clin Invest 2009; 119: 3613-25.
-
(2009)
J Clin Invest
, vol.119
, pp. 3613-3625
-
-
Santos, A.M.1
Jung, J.2
Aziz, N.3
-
84
-
-
78149298209
-
Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha
-
Kraman M, Bambrough PJ, Arnold JN, et al. Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha. Science 2010; 330: 827-30.
-
(2010)
Science
, vol.330
, pp. 827-830
-
-
Kraman, M.1
Bambrough, P.J.2
Arnold, J.N.3
-
85
-
-
0015242348
-
Leucylglycinamide released from oxytocin by human uterine enzyme
-
Walter R, Shlank H, Glass JD, et al. Leucylglycinamide released from oxytocin by human uterine enzyme. Science 1971; 173: 827-9.
-
(1971)
Science
, vol.173
, pp. 827-829
-
-
Walter, R.1
Shlank, H.2
Glass, J.D.3
-
86
-
-
0019277674
-
Distribution of post-proline cleaving enzyme in human brain and the peripheral tissues
-
Kato T, Okada M, Nagatsu T. Distribution of post-proline cleaving enzyme in human brain and the peripheral tissues. Mol Cell Biochem 1980; 32: 117-21.
-
(1980)
Mol Cell Biochem
, vol.32
, pp. 117-121
-
-
Kato, T.1
Okada, M.2
Nagatsu, T.3
-
87
-
-
84867686352
-
Distribution of prolyl oligopeptidase in human peripheral tissues and in ovarian and colorectal tumors
-
Myöhänen TT, Pyykkö E, Männistö PT, et al. Distribution of prolyl oligopeptidase in human peripheral tissues and in ovarian and colorectal tumors. J Histochem Cytochem 2012; 60: 706-15.
-
(2012)
J Histochem Cytochem
, vol.60
, pp. 706-715
-
-
Myöhänen, T.T.1
Pyykkö, E.2
Männistö, P.T.3
-
88
-
-
0030034818
-
Distribution of prolyl oligopeptidase in human peripheral tissues and body fluids
-
Goossens F, De Meester I, Vanhoof G, et al. Distribution of prolyl oligopeptidase in human peripheral tissues and body fluids. Eur J Clin Chem Clin Biochem 1996; 34: 17-22.
-
(1996)
Eur J Clin Chem Clin Biochem
, vol.34
, pp. 17-22
-
-
Goossens, F.1
De Meester, I.2
Vanhoof, G.3
-
89
-
-
84873189046
-
Cigarette smoke-induced collagen destruction; key to chronic neutrophilic airway inflammation
-
Overbeek SA, Braber S, Koelink PJ, et al. Cigarette smoke-induced collagen destruction; key to chronic neutrophilic airway inflammation? PLoS One 2013; 8: e55612.
-
(2013)
PLoS One
, vol.8
, pp. e55612
-
-
Overbeek, S.A.1
Braber, S.2
Koelink, P.J.3
-
90
-
-
23844536770
-
Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion
-
Schulz I, Zeitschel U, Rudolph T, et al. Subcellular localization suggests novel functions for prolyl endopeptidase in protein secretion. J Neurochem 2005; 94: 970-9.
-
(2005)
J Neurochem
, vol.94
, pp. 970-979
-
-
Schulz, I.1
Zeitschel, U.2
Rudolph, T.3
-
92
-
-
33845477051
-
Suggested functions for prolyl oligopeptidase: A puzzling paradox
-
Brandt I, Scharpé S, Lambeir AM. Suggested functions for prolyl oligopeptidase: a puzzling paradox. Clin Chim Acta 2007; 377: 50-61.
-
(2007)
Clin Chim Acta
, vol.377
, pp. 50-61
-
-
Brandt, I.1
Scharpé, S.2
Lambeir, A.M.3
-
93
-
-
45949089501
-
A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation
-
Gaggar A, Jackson PL, Noerager BD, et al. A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation. J Immunol 2008; 180: 5662-9.
-
(2008)
J Immunol
, vol.180
, pp. 5662-5669
-
-
Gaggar, A.1
Jackson, P.L.2
Noerager, B.D.3
-
94
-
-
33644828187
-
A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation
-
Weathington NM, van Houwelingen AH, Noerager BD, et al. A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nat Med 2006; 12: 317-23.
-
(2006)
Nat Med
, vol.12
, pp. 317-323
-
-
Weathington, N.M.1
van Houwelingen, A.H.2
Noerager, B.D.3
-
95
-
-
84987786672
-
Bioactive extracellular matrix fragments in lung health and disease
-
Gaggar A, Weathington N. Bioactive extracellular matrix fragments in lung health and disease. J Clin Invest 2016; 126: 3176-84.
-
(2016)
J Clin Invest
, vol.126
, pp. 3176-3184
-
-
Gaggar, A.1
Weathington, N.2
-
96
-
-
70449624775
-
Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagen
-
O'Reilly PJ, Hardison MT, Jackson PL, et al. Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagen. J Neuroimmunol 2009; 217: 51-4.
-
(2009)
J Neuroimmunol
, vol.217
, pp. 51-54
-
-
O'Reilly, P.J.1
Hardison, M.T.2
Jackson, P.L.3
-
97
-
-
2342466215
-
Prolyl oligopeptidase is involved in release of the antifibrotic peptide Ac-SDKP
-
Cavasin MA, Rhaleb NE, Yang XP, et al. Prolyl oligopeptidase is involved in release of the antifibrotic peptide Ac-SDKP. Hypertension. 2004; 43: 1140-5.
-
(2004)
Hypertension
, vol.43
, pp. 1140-1145
-
-
Cavasin, M.A.1
Rhaleb, N.E.2
Yang, X.P.3
-
98
-
-
49049103926
-
Prolyl oligopeptidase stimulates the aggregation of A-synuclein
-
Brandt I, Gérard M, Sergeant K, et al. Prolyl oligopeptidase stimulates the aggregation of A-synuclein. Peptides 2008; 29: 1472-8.
-
(2008)
Peptides
, vol.29
, pp. 1472-1478
-
-
Brandt, I.1
Gérard, M.2
Sergeant, K.3
-
99
-
-
84929072172
-
Prolyl oligopeptidase enhances a-synuclein dimerization via direct protein-protein interaction
-
Savolainen MH, Yan X, Myöhänen TT, et al. Prolyl oligopeptidase enhances a-synuclein dimerization via direct protein-protein interaction. J Biol Chem 2015; 290: 5117-26.
-
(2015)
J Biol Chem
, vol.290
, pp. 5117-5126
-
-
Savolainen, M.H.1
Yan, X.2
Myöhänen, T.T.3
-
100
-
-
84873699576
-
Prolyl oligopeptidase is a glyceraldehyde-3-phosphate dehydrogenase-binding protein that regulates genotoxic stress-induced cell death
-
Matsuda T, Sakaguchi M, Tanaka S, et al. Prolyl oligopeptidase is a glyceraldehyde-3-phosphate dehydrogenase-binding protein that regulates genotoxic stress-induced cell death. Int J Biochem Cell Biol 2013; 45: 850-7.
-
(2013)
Int J Biochem Cell Biol
, vol.45
, pp. 850-857
-
-
Matsuda, T.1
Sakaguchi, M.2
Tanaka, S.3
-
101
-
-
66949120705
-
Prolyl oligopeptidase binds to GAP-43 and functions without its peptidase activity
-
Di Daniel E, Glover CP, Grot E, et al. Prolyl oligopeptidase binds to GAP-43 and functions without its peptidase activity. Mol Cell Neurosci 2009; 41: 373-82.
-
(2009)
Mol Cell Neurosci
, vol.41
, pp. 373-382
-
-
Di Daniel, E.1
Glover, C.P.2
Grot, E.3
-
102
-
-
77957965147
-
GAP43 shows partial co-localisation but no strong physical interaction with prolyl oligopeptidase
-
Szeltner Z, Morawski M, Juhász T, et al. GAP43 shows partial co-localisation but no strong physical interaction with prolyl oligopeptidase. Biochim Biophys Acta 2010; 1804: 2162-76.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 2162-2176
-
-
Szeltner, Z.1
Morawski, M.2
Juhász, T.3
-
103
-
-
41549120972
-
Cellular and subcellular distribution of rat brain prolyl oligopeptidase and its association with specific neuronal neurotransmitters
-
Myöhanen TT, Venalainen JI, Garcia-Horsman JA, et al. Cellular and subcellular distribution of rat brain prolyl oligopeptidase and its association with specific neuronal neurotransmitters. J Comp Neurol 2008; 507: 1694-708.
-
(2008)
J Comp Neurol
, vol.507
, pp. 1694-1708
-
-
Myöhanen, T.T.1
Venalainen, J.I.2
Garcia-Horsman, J.A.3
-
104
-
-
84874996988
-
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
-
Raj VS, Mou H, Smits SL, et al. Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC. Nature 2013; 495: 251-4.
-
(2013)
Nature
, vol.495
, pp. 251-254
-
-
Raj, V.S.1
Mou, H.2
Smits, S.L.3
-
105
-
-
84955508510
-
Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract: Implications for the Middle East Respiratory Syndrome
-
Meyerholz DK, Lambertz AM, McCray PB. Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract: Implications for the Middle East Respiratory Syndrome. Am J Pathol 2016; 186: 78-86.
-
(2016)
Am J Pathol
, vol.186
, pp. 78-86
-
-
Meyerholz, D.K.1
Lambertz, A.M.2
McCray, P.B.3
-
106
-
-
0031962906
-
Expression of aminopeptidase N and dipeptidyl peptidase IV in the healthy and asthmatic bronchus
-
van der Velden VH, Wierenga-Wolf AF, Adriaansen-Soeting PW, et al. Expression of aminopeptidase N and dipeptidyl peptidase IV in the healthy and asthmatic bronchus. Clin Exp Allergy 1998; 28: 110-20.
-
(1998)
Clin Exp Allergy
, vol.28
, pp. 110-120
-
-
van der Velden, V.H.1
Wierenga-Wolf, A.F.2
Adriaansen-Soeting, P.W.3
-
107
-
-
38049059907
-
Implication of Dipeptidylpeptidase IV Activity in Human Bronchial Inflammation and in Bronchoconstriction Evaluated in Anesthetized Rabbits
-
Landis BN, Grouzmann E, Monod M, et al. Implication of Dipeptidylpeptidase IV Activity in Human Bronchial Inflammation and in Bronchoconstriction Evaluated in Anesthetized Rabbits. Respiration 2008; 75: 89-97.
-
(2008)
Respiration
, vol.75
, pp. 89-97
-
-
Landis, B.N.1
Grouzmann, E.2
Monod, M.3
-
108
-
-
0036634815
-
Loss of dipeptidylpeptidase IV activity in chronic rhinosinusitis contributes to the neurogenic inflammation induced by substance P in the nasal mucosa
-
Grouzmann E, Monod M, Landis B, et al. Loss of dipeptidylpeptidase IV activity in chronic rhinosinusitis contributes to the neurogenic inflammation induced by substance P in the nasal mucosa. FASEB J 2002; 16: 1132-4.
-
(2002)
FASEB J
, vol.16
, pp. 1132-1134
-
-
Grouzmann, E.1
Monod, M.2
Landis, B.3
-
109
-
-
0031460850
-
Peptidases in human bronchoalveolar lining fluid, macrophages, and epithelial cells: Dipeptidyl (amino) peptidase IV, aminopeptidase N, and dipeptidyl (carboxy) peptidase (angiotensin-converting enzyme)
-
Juillerat-Jeanneret L, Aubert JD, Leuenberger P. Peptidases in human bronchoalveolar lining fluid, macrophages, and epithelial cells: dipeptidyl (amino) peptidase IV, aminopeptidase N, and dipeptidyl (carboxy) peptidase (angiotensin-converting enzyme). J Lab Clin Med 1997; 130: 603-14.
-
(1997)
J Lab Clin Med
, vol.130
, pp. 603-614
-
-
Juillerat-Jeanneret, L.1
Aubert, J.D.2
Leuenberger, P.3
-
110
-
-
38649127231
-
Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats
-
Schade J, Stephan M, Schmiedl A, et al. Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats. J Histochem Cytochem 2008; 56: 147-55.
-
(2008)
J Histochem Cytochem
, vol.56
, pp. 147-155
-
-
Schade, J.1
Stephan, M.2
Schmiedl, A.3
-
111
-
-
79953902092
-
Reverse transcription polymerase chain reaction (RT-PCR) analysis of proteolytic enzymes in cultures of human respiratory epithelial cells
-
Baginski L, Tachon G, Falson F, et al. Reverse transcription polymerase chain reaction (RT-PCR) analysis of proteolytic enzymes in cultures of human respiratory epithelial cells. J Aerosol Med Pulm Drug Deliv 2011; 24: 89-101.
-
(2011)
J Aerosol Med Pulm Drug Deliv
, vol.24
, pp. 89-101
-
-
Baginski, L.1
Tachon, G.2
Falson, F.3
-
113
-
-
0242329880
-
Positional cloning of a novel gene influencing asthma from chromosome 2q14
-
Allen M, Heinzmann A, Noguchi E, et al. Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet 2003; 35: 258-63.
-
(2003)
Nat Genet
, vol.35
, pp. 258-263
-
-
Allen, M.1
Heinzmann, A.2
Noguchi, E.3
-
114
-
-
34447553311
-
Dose-dependent recruitment of CD25+ and CD26+ T cells in a novel F344 rat model of asthma
-
Skripuletz T, Schmiedl A, Schade J, et al. Dose-dependent recruitment of CD25+ and CD26+ T cells in a novel F344 rat model of asthma. Am J Physiol Lung Cell Mol Physiol 2007; 292: L1564-71.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.292
, pp. L1564-L1571
-
-
Skripuletz, T.1
Schmiedl, A.2
Schade, J.3
-
115
-
-
0033042983
-
Peptidase activities in serum and bronchoalveolar lavage fluid from allergic asthmatics--comparison with healthy non-smokers and smokers and effects of inhaled glucocorticoids
-
Van Der Velden VH, Naber BA, et al. Peptidase activities in serum and bronchoalveolar lavage fluid from allergic asthmatics--comparison with healthy non-smokers and smokers and effects of inhaled glucocorticoids. Clin Exp Allergy 1999; 29: 813-23.
-
(1999)
Clin Exp Allergy
, vol.29
, pp. 813-823
-
-
Van Der Velden, V.H.1
Naber, B.A.2
-
116
-
-
84978791396
-
Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells
-
Shiobara T, Chibana K, Watanabe T, et al. Dipeptidyl peptidase-4 is highly expressed in bronchial epithelial cells of untreated asthma and it increases cell proliferation along with fibronectin production in airway constitutive cells. Respir Res 2016; 17: 28.
-
(2016)
Respir Res
, vol.17
, pp. 28
-
-
Shiobara, T.1
Chibana, K.2
Watanabe, T.3
-
117
-
-
84878686854
-
Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
-
Fingerlin TE, Murphy E, Zhang W, et al. Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nat Genet 2013; 45: 613-20.
-
(2013)
Nat Genet
, vol.45
, pp. 613-620
-
-
Fingerlin, T.E.1
Murphy, E.2
Zhang, W.3
-
118
-
-
33244490067
-
Fibroblast activation protein: A serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis
-
Acharya PS, Zukas A, Chandan V, et al. Fibroblast activation protein: a serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis. Hum Pathol 2006; 37: 352-60.
-
(2006)
Hum Pathol
, vol.37
, pp. 352-360
-
-
Acharya, P.S.1
Zukas, A.2
Chandan, V.3
-
119
-
-
84964678926
-
Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice
-
Fan MH, Zhu Q, Li HH, et al. Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice. J Biol Chem 2016; 291: 8070-89.
-
(2016)
J Biol Chem
, vol.291
, pp. 8070-8089
-
-
Fan, M.H.1
Zhu, Q.2
Li, H.H.3
-
120
-
-
79551519297
-
Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown
-
Braber S, Koelink PJ, Henricks PA, et al. Cigarette smoke-induced lung emphysema in mice is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown. Am J Physiol Lung Cell Mol Physiol 2011; 300: L255-65.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, vol.300
, pp. L255-L265
-
-
Braber, S.1
Koelink, P.J.2
Henricks, P.A.3
-
121
-
-
84963823800
-
Toll-like receptor 4 engagement mediates prolyl endopeptidase release from airway epithelia via exosomes
-
Szul T, Bratcher PE, Fraser KB, et al. Toll-like receptor 4 engagement mediates prolyl endopeptidase release from airway epithelia via exosomes. Am J Respir Cell Mol Biol 2016; 54: 359-69.
-
(2016)
Am J Respir Cell Mol Biol
, vol.54
, pp. 359-369
-
-
Szul, T.1
Bratcher, P.E.2
Fraser, K.B.3
-
123
-
-
44249086425
-
Non-small cell lung cancer: Epidemiology, risk factors, treatment, and survivorship
-
Molina JR, Yang P, Cassivi SD, et al. Non-small cell lung cancer: epidemiology, risk factors, treatment, and survivorship. Mayo Clin Proc 2008; 83: 584-94.
-
(2008)
Mayo Clin Proc
, vol.83
, pp. 584-594
-
-
Molina, J.R.1
Yang, P.2
Cassivi, S.D.3
-
124
-
-
0027179525
-
Expression of dipeptidyl aminopeptidase IV activity in human lung carcinoma
-
Asada Y, Aratake Y, Kotani T, et al. Expression of dipeptidyl aminopeptidase IV activity in human lung carcinoma. Histopathology 1993; 23: 265-70.
-
(1993)
Histopathology
, vol.23
, pp. 265-270
-
-
Asada, Y.1
Aratake, Y.2
Kotani, T.3
-
125
-
-
3442890045
-
Role for dipeptidyl peptidase IV in tumor suppression of human non small cell lung carcinoma cells
-
Wesley UV, Tiwari S, Houghton AN. Role for dipeptidyl peptidase IV in tumor suppression of human non small cell lung carcinoma cells. Int J Cancer 2004; 109: 855-66.
-
(2004)
Int J Cancer
, vol.109
, pp. 855-866
-
-
Wesley, U.V.1
Tiwari, S.2
Houghton, A.N.3
-
126
-
-
0025872297
-
Dipeptidyl peptidase IV prolyl endopeptidase and cathepsin B activities in primary human lung tumours and lung parenchyma
-
Šedo A, Krepela E, Kasafírek E. Dipeptidyl peptidase IV prolyl endopeptidase and cathepsin B activities in primary human lung tumours and lung parenchyma. J Cancer Res Clin Oncol 1991; 117: 249-53.
-
(1991)
J Cancer Res Clin Oncol
, vol.117
, pp. 249-253
-
-
Šedo, A.1
Krepela, E.2
Kasafírek, E.3
-
127
-
-
57949084030
-
Synthesis and use of 4-peptidylhydrazido-N-hexyl-1, 8-naphthalimides as fluorogenic histochemical substrates for dipeptidyl peptidase IV and tripeptidyl peptidase I
-
Ivanov I, Tasheva D, Todorova R, et al. Synthesis and use of 4-peptidylhydrazido-N-hexyl-1, 8-naphthalimides as fluorogenic histochemical substrates for dipeptidyl peptidase IV and tripeptidyl peptidase I. Eur J Med Chem 2009; 44: 384-92.
-
(2009)
Eur J Med Chem
, vol.44
, pp. 384-392
-
-
Ivanov, I.1
Tasheva, D.2
Todorova, R.3
-
128
-
-
84857191627
-
Comparison of the activity levels and localization of dipeptidyl peptidase IV in normal and tumor human lung cells
-
Dimitrova M, Ivanov I, Todorova R, et al. Comparison of the activity levels and localization of dipeptidyl peptidase IV in normal and tumor human lung cells. Tissue Cell 2012; 44: 74-9.
-
(2012)
Tissue Cell
, vol.44
, pp. 74-79
-
-
Dimitrova, M.1
Ivanov, I.2
Todorova, R.3
-
129
-
-
0024205414
-
Dipeptidylpeptidase IV--inactivation with N-peptidyl-O-aroyl hydroxylamines
-
Demuth HU, Baumgrass R, Schaper C, et al. Dipeptidylpeptidase IV--inactivation with N-peptidyl-O-aroyl hydroxylamines. J Enzyme Inhib 1988; 2: 129-42.
-
(1988)
J Enzyme Inhib
, vol.2
, pp. 129-142
-
-
Demuth, H.U.1
Baumgrass, R.2
Schaper, C.3
-
130
-
-
0026785764
-
Characterization of dipeptidyl peptidase IV (CD26) from human lymphocytes
-
De Meester I, Vanhoof G, Hendriks D, et al. Characterization of dipeptidyl peptidase IV (CD26) from human lymphocytes. Clin Chim Acta 1992; 210: 23-34.
-
(1992)
Clin Chim Acta
, vol.210
, pp. 23-34
-
-
De Meester, I.1
Vanhoof, G.2
Hendriks, D.3
-
131
-
-
0021956050
-
Dipeptidyl peptidase IV in mammalian lungs
-
Křepela E, Vičcar J, Žižková L, et al. Dipeptidyl peptidase IV in mammalian lungs. Lung 1985; 163: 33-54.
-
(1985)
Lung
, vol.163
, pp. 33-54
-
-
Křepela, E.1
Vičcar, J.2
Žižková, L.3
-
132
-
-
84882724223
-
Clinical implications of fibroblast activation protein-A in non-small cell lung cancer after curative resection: A new predictor for prognosis
-
Liao Y, Ni Y, He R, et al. Clinical implications of fibroblast activation protein-A in non-small cell lung cancer after curative resection: a new predictor for prognosis. J Cancer Res Clin Oncol 2013; 139: 1523-8.
-
(2013)
J Cancer Res Clin Oncol
, vol.139
, pp. 1523-1528
-
-
Liao, Y.1
Ni, Y.2
He, R.3
-
133
-
-
67649666985
-
Phase II trial of talabostat and docetaxel in advanced non-small cell lung cancer
-
Eager RM, Cunningham CC, Senzer N, et al. Phase II trial of talabostat and docetaxel in advanced non-small cell lung cancer. Clin Oncol (R Coll Radiol) 2009; 21: 464-72.
-
(2009)
Clin Oncol (R Coll Radiol)
, vol.21
, pp. 464-472
-
-
Eager, R.M.1
Cunningham, C.C.2
Senzer, N.3
-
134
-
-
34547126892
-
Humanized anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors
-
Inamoto T, Yamada T, Ohnuma K, et al. Humanized anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors. Clin Cancer Res 2007; 13: 4191-200.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4191-4200
-
-
Inamoto, T.1
Yamada, T.2
Ohnuma, K.3
-
135
-
-
84919687999
-
Clinical Significance of Soluble CD26 in Malignant Pleural Mesothelioma. Altomare DA, editor
-
Fujimoto N, Ohnuma K, Aoe K, et al. Clinical Significance of Soluble CD26 in Malignant Pleural Mesothelioma. Altomare DA, editor. PLoS One 2014; 9: e115647.
-
(2014)
PLoS One
, vol.9
, pp. e115647
-
-
Fujimoto, N.1
Ohnuma, K.2
Aoe, K.3
-
136
-
-
84926471849
-
In-depth proteomic analysis of six types of exudative pleural effusions for nonsmall cell lung cancer biomarker discovery
-
Liu PJ, Chen CD, Wang CL, et al. In-depth proteomic analysis of six types of exudative pleural effusions for nonsmall cell lung cancer biomarker discovery. Mol Cell Proteomics 2015; 14: 917-32.
-
(2015)
Mol Cell Proteomics
, vol.14
, pp. 917-932
-
-
Liu, P.J.1
Chen, C.D.2
Wang, C.L.3
-
137
-
-
71549125581
-
Concurrent measurement of adenosine deaminase and dipeptidyl peptidase IV activity in the diagnosis of tuberculous pleural effusion
-
Küpeli E, Karnak D, Elgün S, et al. Concurrent measurement of adenosine deaminase and dipeptidyl peptidase IV activity in the diagnosis of tuberculous pleural effusion. Diagn Microbiol Infect Dis 2009; 65: 365-71.
-
(2009)
Diagn Microbiol Infect Dis
, vol.65
, pp. 365-371
-
-
Küpeli, E.1
Karnak, D.2
Elgün, S.3
-
138
-
-
84455161028
-
Clinical diagnostic utility of adenosine deaminase, interferon-γ, interferon-γ-induced protein of 10 kDa, and dipeptidyl peptidase 4 levels in tuberculous pleural effusions
-
Wang H, Yue J, Yang J, et al. Clinical diagnostic utility of adenosine deaminase, interferon-γ, interferon-γ-induced protein of 10 kDa, and dipeptidyl peptidase 4 levels in tuberculous pleural effusions. Heart Lung 2012; 41: 70-5.
-
(2012)
Heart Lung
, vol.41
, pp. 70-75
-
-
Wang, H.1
Yue, J.2
Yang, J.3
-
139
-
-
0019469755
-
Proteolytic enzymes in bronchopulmonary lavage fluids: Cathepsin B-like activity and prolyl endopeptidase
-
Orlowski M, Orlowski J, Lesser M, et al. Proteolytic enzymes in bronchopulmonary lavage fluids: cathepsin B-like activity and prolyl endopeptidase. J Lab Clin Med 1981; 97: 467-76.
-
(1981)
J Lab Clin Med
, vol.97
, pp. 467-476
-
-
Orlowski, M.1
Orlowski, J.2
Lesser, M.3
-
140
-
-
64249122210
-
The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation
-
Hardison MT, Galin FS, Calderon CE, et al. The presence of a matrix-derived neutrophil chemoattractant in bronchiolitis obliterans syndrome after lung transplantation. J Immunol 2009; 182: 4423-31.
-
(2009)
J Immunol
, vol.182
, pp. 4423-4431
-
-
Hardison, M.T.1
Galin, F.S.2
Calderon, C.E.3
-
141
-
-
84867847993
-
Dipeptidyl peptidase 4 as a therapeutic target in ischemia/ reperfusion injury
-
Matheeussen V, Jungraithmayr W, De Meester I. Dipeptidyl peptidase 4 as a therapeutic target in ischemia/ reperfusion injury. Pharmacol Ther 2012; 136: 267-82.
-
(2012)
Pharmacol Ther
, vol.136
, pp. 267-282
-
-
Matheeussen, V.1
Jungraithmayr, W.2
De Meester, I.3
-
142
-
-
85032070990
-
Fibroblast Activation Protein (fap) Modulates Host Defense Against Bacterial Pneumonia In Mice
-
Hulver M, Lee JS, Fan M. Fibroblast Activation Protein (fap) Modulates Host Defense Against Bacterial Pneumonia In Mice. Am J Respir Crit Care Med 2015; 191: A6408.
-
(2015)
Am J Respir Crit Care Med
, vol.191
, pp. A6408
-
-
Hulver, M.1
Lee, J.S.2
Fan, M.3
-
143
-
-
84924662887
-
Dipeptidyl peptidase-4 inhibitors and the risk of community-acquired pneumonia in patients with type 2 diabetes
-
Faillie JL, Filion KB, Patenaude V, et al. Dipeptidyl peptidase-4 inhibitors and the risk of community-acquired pneumonia in patients with type 2 diabetes. Diabetes Obes Metab 2015; 17: 379-85.
-
(2015)
Diabetes Obes Metab
, vol.17
, pp. 379-385
-
-
Faillie, J.L.1
Filion, K.B.2
Patenaude, V.3
-
144
-
-
84948971364
-
Use of Dipeptidyl-Peptidase-4 Inhibitors and the Risk of Pneumonia: A Population-Based Cohort Study
-
van der Zanden RW, de Vries F, Lalmohamed A, et al. Use of Dipeptidyl-Peptidase-4 Inhibitors and the Risk of Pneumonia: A Population-Based Cohort Study. PLoS One 2015; 10: e0139367.
-
(2015)
PLoS One
, vol.10
, pp. e0139367
-
-
van der Zanden, R.W.1
de Vries, F.2
Lalmohamed, A.3
|