메뉴 건너뛰기




Volumn 4, Issue , 2014, Pages 43-54

Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs

(26)  Keane, Fiona M a,b   Yao, Tsun Wen a,b,h   Seelk, Stefanie a   Gall, Margaret G a,b   Chowdhury, Sumaiya a,b   Poplawski, Sarah E c   Lai, Jack H c   Li, Youhua c   Wu, Wengen c   Farrell, Penny d   Vieira de Ribeiro, Ana Julia a,b   Osborne, Brenna a,b,i   Yu, Denise M T a,b,j   Seth, Devanshi a,d   Rahman, Khairunnessa d   Haber, Paul b,d   Topaloglu, A Kemal e   Wang, Chuanmin b,d   Thomson, Sally b,d   Hennessy, Annemarie d,f   more..


Author keywords

Biomarker; Dipeptidyl peptidase; Fibroblast; Fibrosis; Liver disease; Protease activity; Protease substrates

Indexed keywords

FIBROBLAST ACTIVATION PROTEIN; PROTEINASE; UNCLASSIFIED DRUG; PROTEIN;

EID: 84890386346     PISSN: 22115463     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fob.2013.12.001     Document Type: Article
Times cited : (97)

References (73)
  • 1
    • 84859366447 scopus 로고    scopus 로고
    • Protease signalling: the cutting edge
    • Turk B., Turk D., Turk V. Protease signalling: the cutting edge. EMBO J. 2012, 31:1630-1643.
    • (2012) EMBO J. , vol.31 , pp. 1630-1643
    • Turk, B.1    Turk, D.2    Turk, V.3
  • 2
    • 84884875512 scopus 로고    scopus 로고
    • Fibroblast activation protein alpha
    • Elsevier, San Diego
    • Gorrell MD., Park J.E. Fibroblast activation protein alpha. Handbook of Proteolytic Enzymes 2013, 3395-3401. Elsevier, San Diego. third ed.
    • (2013) Handbook of Proteolytic Enzymes , pp. 3395-3401
    • Gorrell, M.D.1    Park, J.E.2
  • 4
    • 17144404555 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders
    • Gorrell M.D. Dipeptidyl peptidase IV and related enzymes in cell biology and liver disorders. Clin. Sci. (Lond) 2005, 108:277-292.
    • (2005) Clin. Sci. (Lond) , vol.108 , pp. 277-292
    • Gorrell, M.D.1
  • 5
    • 84859744404 scopus 로고    scopus 로고
    • When GLP-1 hits the liver: a novel approach for insulin resistance and NASH
    • Kim Y.O., Schuppan D. When GLP-1 hits the liver: a novel approach for insulin resistance and NASH. Am. J. Physiol. Gastrointest. Liver Physiol. 2012, 302:G759-G761.
    • (2012) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.302
    • Kim, Y.O.1    Schuppan, D.2
  • 6
    • 79953729051 scopus 로고    scopus 로고
    • Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α
    • Keane F.M., Nadvi N.A., Yao T.-W., Gorrell M.D. Neuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-α. FEBS. J. 2011, 278:1316-1332.
    • (2011) FEBS. J. , vol.278 , pp. 1316-1332
    • Keane, F.M.1    Nadvi, N.A.2    Yao, T.-W.3    Gorrell, M.D.4
  • 7
    • 0033034717 scopus 로고    scopus 로고
    • Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis
    • Levy M.T., McCaughan G.W., Abbott C.A., Park J.E., Cunningham A.M., Muller E., Rettig W.J., Gorrell M.D. Fibroblast activation protein: a cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis. Hepatology 1999, 29:1768-1778.
    • (1999) Hepatology , vol.29 , pp. 1768-1778
    • Levy, M.T.1    McCaughan, G.W.2    Abbott, C.A.3    Park, J.E.4    Cunningham, A.M.5    Muller, E.6    Rettig, W.J.7    Gorrell, M.D.8
  • 8
    • 0033579444 scopus 로고    scopus 로고
    • Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts
    • Park J.E., Lenter M.C., Zimmermann R.N., Garin-Chesa P., Old L.J., Rettig W.J. Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts. J. Biol. Chem. 1999, 274:36505-36512.
    • (1999) J. Biol. Chem. , vol.274 , pp. 36505-36512
    • Park, J.E.1    Lenter, M.C.2    Zimmermann, R.N.3    Garin-Chesa, P.4    Old, L.J.5    Rettig, W.J.6
  • 9
    • 2342447229 scopus 로고    scopus 로고
    • A novel plasma proteinase potentiates alpha2-antiplasmin inhibition of fibrin digestion
    • Lee K.N., Jackson K.W., Christiansen V.J., Chung K.H., McKee P.A. A novel plasma proteinase potentiates alpha2-antiplasmin inhibition of fibrin digestion. Bloodd 2004, 103:3783-3788.
    • (2004) Bloodd , vol.103 , pp. 3783-3788
    • Lee, K.N.1    Jackson, K.W.2    Christiansen, V.J.3    Chung, K.H.4    McKee, P.A.5
  • 10
    • 32644446428 scopus 로고    scopus 로고
    • Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein
    • Lee K.N., Jackson K.W., Christiansen V.J., Lee C.S., Chun J.G., McKee P.A. Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein. Blood 2006, 107:1397-1404.
    • (2006) Blood , vol.107 , pp. 1397-1404
    • Lee, K.N.1    Jackson, K.W.2    Christiansen, V.J.3    Lee, C.S.4    Chun, J.G.5    McKee, P.A.6
  • 12
    • 80455158257 scopus 로고    scopus 로고
    • Expression and role of fibroblast activation protein-alpha in microinvasive breast carcinoma
    • Hua X., Yu L., Huang X., Liao Z., Xian Q. Expression and role of fibroblast activation protein-alpha in microinvasive breast carcinoma. Diagn. Pathol. 2011, 6:111.
    • (2011) Diagn. Pathol. , vol.6 , pp. 111
    • Hua, X.1    Yu, L.2    Huang, X.3    Liao, Z.4    Xian, Q.5
  • 13
    • 79953302670 scopus 로고    scopus 로고
    • Expression and role of the cell surface protease seprase/fibroblast activation protein-alpha (FAP-alpha) in astroglial tumors
    • Mentlein R., Hattermann K., Hemion C., Jungbluth A.A., Held-Feindt J. Expression and role of the cell surface protease seprase/fibroblast activation protein-alpha (FAP-alpha) in astroglial tumors. Biol. Chem. 2011, 392:199-207.
    • (2011) Biol. Chem. , vol.392 , pp. 199-207
    • Mentlein, R.1    Hattermann, K.2    Hemion, C.3    Jungbluth, A.A.4    Held-Feindt, J.5
  • 14
    • 84863285103 scopus 로고    scopus 로고
    • Expression of fibroblast activation protein in human pancreatic adenocarcinoma and its clinicopathological significance
    • Shi M., Yu D.H., Chen Y., Zhao C.Y., Zhang J., Liu Q.H., Ni C.R., Zhu M.H. Expression of fibroblast activation protein in human pancreatic adenocarcinoma and its clinicopathological significance. World J. Gastroenterol. 2012, 18:840-846.
    • (2012) World J. Gastroenterol. , vol.18 , pp. 840-846
    • Shi, M.1    Yu, D.H.2    Chen, Y.3    Zhao, C.Y.4    Zhang, J.5    Liu, Q.H.6    Ni, C.R.7    Zhu, M.H.8
  • 15
    • 25844455319 scopus 로고    scopus 로고
    • Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line
    • Wang X.M., Yu D.M., McCaughan G.W., Gorrell M.D. Fibroblast activation protein increases apoptosis, cell adhesion, and migration by the LX-2 human stellate cell line. Hepatology 2005, 42:935-945.
    • (2005) Hepatology , vol.42 , pp. 935-945
    • Wang, X.M.1    Yu, D.M.2    McCaughan, G.W.3    Gorrell, M.D.4
  • 18
    • 0025083528 scopus 로고
    • Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers
    • Garin-Chesa P., Old L.J., Rettig W.J. Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers. Proc. Natl. Acad. Sci. U.S.A. 1990, 87:7235-7239.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 7235-7239
    • Garin-Chesa, P.1    Old, L.J.2    Rettig, W.J.3
  • 19
    • 84856934228 scopus 로고    scopus 로고
    • Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy
    • Brennen W.N., Isaacs J.T., Denmeade S.R. Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy. Mol. Cancer Ther. 2012, 11:257-266.
    • (2012) Mol. Cancer Ther. , vol.11 , pp. 257-266
    • Brennen, W.N.1    Isaacs, J.T.2    Denmeade, S.R.3
  • 20
    • 84863116741 scopus 로고    scopus 로고
    • Fibroblast activation protein: a potential therapeutic target in cancer
    • Liu R., Li H., Liu L., Yu J., Ren X. Fibroblast activation protein: a potential therapeutic target in cancer. Cancer Biol. Ther. 2012, 13:123-129.
    • (2012) Cancer Biol. Ther. , vol.13 , pp. 123-129
    • Liu, R.1    Li, H.2    Liu, L.3    Yu, J.4    Ren, X.5
  • 21
    • 78049442950 scopus 로고    scopus 로고
    • Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model
    • Wen Y., Wang C., Ma T., Li Z., Zhou L., Mu B., Leng F., Shi H., Li Y., Wei Y. Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model. Cancer Sci 2010, 101:2325-2332.
    • (2010) Cancer Sci , vol.101 , pp. 2325-2332
    • Wen, Y.1    Wang, C.2    Ma, T.3    Li, Z.4    Zhou, L.5    Mu, B.6    Leng, F.7    Shi, H.8    Li, Y.9    Wei, Y.10
  • 22
    • 0035723325 scopus 로고    scopus 로고
    • CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes
    • Gorrell M.D., Gysbers V., McCaughan G.W. CD26: a multifunctional integral membrane and secreted protein of activated lymphocytes. Scand. J. Immunol. 2001, 54:249-264.
    • (2001) Scand. J. Immunol. , vol.54 , pp. 249-264
    • Gorrell, M.D.1    Gysbers, V.2    McCaughan, G.W.3
  • 24
    • 0025349737 scopus 로고
    • Identification of the bile canalicular cell surface molecule GP110 as the ectopeptidase dipeptidyl peptidase IV: an analysis by tissue distribution, purification and N-terminal amino acid sequence
    • McCaughan G.W., Wickson J.E., Creswick P.F., Gorrell M.D. Identification of the bile canalicular cell surface molecule GP110 as the ectopeptidase dipeptidyl peptidase IV: an analysis by tissue distribution, purification and N-terminal amino acid sequence. Hepatology 1990, 11:534-544.
    • (1990) Hepatology , vol.11 , pp. 534-544
    • McCaughan, G.W.1    Wickson, J.E.2    Creswick, P.F.3    Gorrell, M.D.4
  • 26
    • 0027215348 scopus 로고
    • Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum
    • Mentlein R., Gallwitz B., Schmidt W.E. Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide-1(7-36)amide, peptide histidine methionine and is responsible for their degradation in human serum. Eur. J. Biochem. 1993, 214:829-835.
    • (1993) Eur. J. Biochem. , vol.214 , pp. 829-835
    • Mentlein, R.1    Gallwitz, B.2    Schmidt, W.E.3
  • 27
    • 0017846443 scopus 로고
    • Liver dipeptidyl aminopeptidase IV hydrolyzes substance P
    • Heymann E., Mentlein R. Liver dipeptidyl aminopeptidase IV hydrolyzes substance P. FEBS Lett. 1978, 91:360-364.
    • (1978) FEBS Lett. , vol.91 , pp. 360-364
    • Heymann, E.1    Mentlein, R.2
  • 28
    • 0027494070 scopus 로고
    • Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV
    • Mentlein R., Dahms P., Grandt D., Kruger R. Proteolytic processing of neuropeptide Y and peptide YY by dipeptidyl peptidase IV. Regul. Pept. 1993, 49:133-144.
    • (1993) Regul. Pept. , vol.49 , pp. 133-144
    • Mentlein, R.1    Dahms, P.2    Grandt, D.3    Kruger, R.4
  • 29
    • 0030819309 scopus 로고    scopus 로고
    • Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage
    • Oravecz T., Pall M., Roderiquez G., Gorrell M.D., Ditto M., Nguyen N.Y., Boykins R., Unsworth E., Norcross M.A. Regulation of the receptor specificity and function of the chemokine RANTES (regulated on activation, normal T cell expressed and secreted) by dipeptidyl peptidase IV (CD26)-mediated cleavage. J. Exp. Med. 1997, 186:1865-1872.
    • (1997) J. Exp. Med. , vol.186 , pp. 1865-1872
    • Oravecz, T.1    Pall, M.2    Roderiquez, G.3    Gorrell, M.D.4    Ditto, M.5    Nguyen, N.Y.6    Boykins, R.7    Unsworth, E.8    Norcross, M.A.9
  • 30
    • 0034284379 scopus 로고    scopus 로고
    • Cleavage by CD26/dipeptidyl peptidase IV converts the chemokine LD78beta into a most efficient monocyte attractant and CCR1 agonist
    • Proost P., Menten P., Struyf S., Schutyser E., De Meester I., Van Damme J. Cleavage by CD26/dipeptidyl peptidase IV converts the chemokine LD78beta into a most efficient monocyte attractant and CCR1 agonist. Blood 2000, 96:1674-1680.
    • (2000) Blood , vol.96 , pp. 1674-1680
    • Proost, P.1    Menten, P.2    Struyf, S.3    Schutyser, E.4    De Meester, I.5    Van Damme, J.6
  • 31
    • 70349774693 scopus 로고    scopus 로고
    • On the origin of serum CD26 and its altered concentration in cancer patients
    • Cordero O.J., Salgado F.J., Nogueira M. On the origin of serum CD26 and its altered concentration in cancer patients. Cancer Immunol. Immunother. 2009, 58:1723-1747.
    • (2009) Cancer Immunol. Immunother. , vol.58 , pp. 1723-1747
    • Cordero, O.J.1    Salgado, F.J.2    Nogueira, M.3
  • 32
    • 79960634133 scopus 로고    scopus 로고
    • CD26/dipeptidyl-peptidase IV and adenosine deaminase serum levels in psoriatic patients treated with cyclosporine, etanercept, and psoralen plus ultraviolet A phototherapy
    • Yildirim F.E., Karaduman A., Pinar A., Aksoy Y. CD26/dipeptidyl-peptidase IV and adenosine deaminase serum levels in psoriatic patients treated with cyclosporine, etanercept, and psoralen plus ultraviolet A phototherapy. Int. J. Dermatol. 2011, 50:948-955.
    • (2011) Int. J. Dermatol. , vol.50 , pp. 948-955
    • Yildirim, F.E.1    Karaduman, A.2    Pinar, A.3    Aksoy, Y.4
  • 33
    • 77956283713 scopus 로고    scopus 로고
    • Biomarkers in chronic fatigue syndrome: evaluation of natural killer cell function and dipeptidyl peptidase IV/CD26
    • Fletcher M.A., Zeng X.R., Maher K., Levis S., Hurwitz B., Antoni M., Broderick G., Klimas N.G. Biomarkers in chronic fatigue syndrome: evaluation of natural killer cell function and dipeptidyl peptidase IV/CD26. PLoS One 2010, 5:e10817.
    • (2010) PLoS One , vol.5
    • Fletcher, M.A.1    Zeng, X.R.2    Maher, K.3    Levis, S.4    Hurwitz, B.5    Antoni, M.6    Broderick, G.7    Klimas, N.G.8
  • 34
    • 71549125581 scopus 로고    scopus 로고
    • Concurrent measurement of adenosine deaminase and dipeptidyl peptidase IV activity in the diagnosis of tuberculous pleural effusion
    • Kupeli E., Karnak D., Elgun S., Arguder E., Kayacan O. Concurrent measurement of adenosine deaminase and dipeptidyl peptidase IV activity in the diagnosis of tuberculous pleural effusion. Diagn. Microbiol. Infect. Dis. 2009, 65:365-371.
    • (2009) Diagn. Microbiol. Infect. Dis. , vol.65 , pp. 365-371
    • Kupeli, E.1    Karnak, D.2    Elgun, S.3    Arguder, E.4    Kayacan, O.5
  • 37
  • 38
    • 84857368462 scopus 로고    scopus 로고
    • Upregulation of CD26 expression in epithelial cells and stromal cells during wound-induced skin tumour formation
    • Arwert E.N., Mentink R.A., Driskell R.R., Hoste E., Goldie S.J., Quist S., Watt F.M. Upregulation of CD26 expression in epithelial cells and stromal cells during wound-induced skin tumour formation. Oncogene 2012, 31:992-1000.
    • (2012) Oncogene , vol.31 , pp. 992-1000
    • Arwert, E.N.1    Mentink, R.A.2    Driskell, R.R.3    Hoste, E.4    Goldie, S.J.5    Quist, S.6    Watt, F.M.7
  • 40
    • 84861498078 scopus 로고    scopus 로고
    • Plasma seprase and DPP4 levels as markers of disease and prognosis in cancer
    • Javidroozi M., Zucker S., Chen W.T. Plasma seprase and DPP4 levels as markers of disease and prognosis in cancer. Dis. Markers 2012, 32:309-320.
    • (2012) Dis. Markers , vol.32 , pp. 309-320
    • Javidroozi, M.1    Zucker, S.2    Chen, W.T.3
  • 43
    • 33749064594 scopus 로고    scopus 로고
    • Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake
    • Ryskjaer J., Deacon C.F., Carr R.D., Krarup T., Madsbad S., Holst J., Vilsboll T. Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake. Eur. J. Endocrinol. 2006, 155:485-493.
    • (2006) Eur. J. Endocrinol. , vol.155 , pp. 485-493
    • Ryskjaer, J.1    Deacon, C.F.2    Carr, R.D.3    Krarup, T.4    Madsbad, S.5    Holst, J.6    Vilsboll, T.7
  • 44
    • 37549030476 scopus 로고    scopus 로고
    • Decreased dipeptidyl peptidase-IV activity and glucagon-like peptide-1(7-36)amide degradation in type 2 diabetic subjects
    • McKillop A.M., Duffy N.A., Lindsay J.R., O'Harte F.P., Bell P.M., Flatt P.R. Decreased dipeptidyl peptidase-IV activity and glucagon-like peptide-1(7-36)amide degradation in type 2 diabetic subjects. Diabetes Res. Clin. Pract. 2008, 79:79-85.
    • (2008) Diabetes Res. Clin. Pract. , vol.79 , pp. 79-85
    • McKillop, A.M.1    Duffy, N.A.2    Lindsay, J.R.3    O'Harte, F.P.4    Bell, P.M.5    Flatt, P.R.6
  • 45
    • 0034090145 scopus 로고    scopus 로고
    • Effect of ageing and diabetes on glucose-dependent insulinotropic polypeptide and dipeptidyl peptidase IV responses to oral glucose
    • Meneilly G.S., Demuth H.U., McIntosh C.H., Pederson R.A. Effect of ageing and diabetes on glucose-dependent insulinotropic polypeptide and dipeptidyl peptidase IV responses to oral glucose. Diabet. Med. 2000, 17:346-350.
    • (2000) Diabet. Med. , vol.17 , pp. 346-350
    • Meneilly, G.S.1    Demuth, H.U.2    McIntosh, C.H.3    Pederson, R.A.4
  • 46
    • 84864285404 scopus 로고    scopus 로고
    • Comparative analysis of the substrate preferences of two post-proline cleaving endopeptidases, prolyl oligopeptidase and fibroblast activation protein alpha
    • Jambunathan K., Watson D.S., Endsley A.N., Kodukula K., Galande A.K. Comparative analysis of the substrate preferences of two post-proline cleaving endopeptidases, prolyl oligopeptidase and fibroblast activation protein alpha. FEBS Lett. 2012, 586:2507-2512.
    • (2012) FEBS Lett. , vol.586 , pp. 2507-2512
    • Jambunathan, K.1    Watson, D.S.2    Endsley, A.N.3    Kodukula, K.4    Galande, A.K.5
  • 47
    • 0030984797 scopus 로고    scopus 로고
    • Mouse fibroblast activation protein: molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers
    • Niedermeyer J., Scanlan M.J., Garin-Chesa P., Daiber C., Fiebig H.H., Old L.J., Rettig W.J., Schnapp A. Mouse fibroblast activation protein: molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers. Int. J. Cancer. 1997, 71:383-389.
    • (1997) Int. J. Cancer. , vol.71 , pp. 383-389
    • Niedermeyer, J.1    Scanlan, M.J.2    Garin-Chesa, P.3    Daiber, C.4    Fiebig, H.H.5    Old, L.J.6    Rettig, W.J.7    Schnapp, A.8
  • 48
    • 84881137761 scopus 로고    scopus 로고
    • Overexpression of fibroblast activation protein and its clinical implications in patients with osteosarcoma
    • Yuan D., Liu B., Liu K., Zhu G., Dai Z., Xie Y. Overexpression of fibroblast activation protein and its clinical implications in patients with osteosarcoma. J. Surg. Oncol. 2013, 108:157-162.
    • (2013) J. Surg. Oncol. , vol.108 , pp. 157-162
    • Yuan, D.1    Liu, B.2    Liu, K.3    Zhu, G.4    Dai, Z.5    Xie, Y.6
  • 49
    • 84870173118 scopus 로고    scopus 로고
    • Fibroblast activation protein in remodeling tissues
    • Jacob M., Chang L., Pure E. Fibroblast activation protein in remodeling tissues. Curr. Mol. Med. 2012, 12:1220-1243.
    • (2012) Curr. Mol. Med. , vol.12 , pp. 1220-1243
    • Jacob, M.1    Chang, L.2    Pure, E.3
  • 50
    • 84875654374 scopus 로고    scopus 로고
    • Targeting inhibition of fibroblast activation protein-α and prolyl oligopeptidase activities on cells common to metastatic tumor microenvironments
    • Christiansen V.J., Jackson K.W., Lee K.N., Downs T.D., McKee P.A. Targeting inhibition of fibroblast activation protein-α and prolyl oligopeptidase activities on cells common to metastatic tumor microenvironments. Neoplasia 2013, 15:348-358.
    • (2013) Neoplasia , vol.15 , pp. 348-358
    • Christiansen, V.J.1    Jackson, K.W.2    Lee, K.N.3    Downs, T.D.4    McKee, P.A.5
  • 52
    • 66849125864 scopus 로고    scopus 로고
    • Targeting cancer stroma with a fibroblast activation protein-activated promelittin protoxin
    • LeBeau A.M., Brennen W.N., Aggarwal S., Denmeade S.R. Targeting cancer stroma with a fibroblast activation protein-activated promelittin protoxin. Mol. Cancer Ther. 2009, 8:1378-1386.
    • (2009) Mol. Cancer Ther. , vol.8 , pp. 1378-1386
    • LeBeau, A.M.1    Brennen, W.N.2    Aggarwal, S.3    Denmeade, S.R.4
  • 54
    • 84880626610 scopus 로고    scopus 로고
    • Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse model
    • Cai F., Li Z., Wang C., Xian S., Xu G., Peng F., Wei Y., Lu Y. Short hairpin RNA targeting of fibroblast activation protein inhibits tumor growth and improves the tumor microenvironment in a mouse model. BMB Rep. 2013, 46:252-257.
    • (2013) BMB Rep. , vol.46 , pp. 252-257
    • Cai, F.1    Li, Z.2    Wang, C.3    Xian, S.4    Xu, G.5    Peng, F.6    Wei, Y.7    Lu, Y.8
  • 55
    • 84880687861 scopus 로고    scopus 로고
    • Depletion of stromal cells expressing fibroblast activation protein-alpha from skeletal muscle and bone marrow results in cachexia and anemia
    • Roberts E.W., Deonarine A., Jones J.O., Denton A.E., Feig C., Lyons S.K., Espeli M., Kraman M., McKenna B., Wells R.J., et al. Depletion of stromal cells expressing fibroblast activation protein-alpha from skeletal muscle and bone marrow results in cachexia and anemia. J. Exp. Med. 2013, 210:1137-1151.
    • (2013) J. Exp. Med. , vol.210 , pp. 1137-1151
    • Roberts, E.W.1    Deonarine, A.2    Jones, J.O.3    Denton, A.E.4    Feig, C.5    Lyons, S.K.6    Espeli, M.7    Kraman, M.8    McKenna, B.9    Wells, R.J.10
  • 56
    • 84880656055 scopus 로고    scopus 로고
    • Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
    • Tran E., Chinnasamy D., Yu Z., Morgan R.A., Lee C.C., Restifo N.P., Rosenberg S.A. Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia. J. Exp. Med. 2013, 210:1125-1135.
    • (2013) J. Exp. Med. , vol.210 , pp. 1125-1135
    • Tran, E.1    Chinnasamy, D.2    Yu, Z.3    Morgan, R.A.4    Lee, C.C.5    Restifo, N.P.6    Rosenberg, S.A.7
  • 57
    • 84890347883 scopus 로고    scopus 로고
    • Cancerous tissues from human patients contain far higher levels of fibroblast activation protein enzyme activity than corresponding mouse xenografts as revealed using ARI-3144, a new highly specific substrate assay
    • Submitted
    • Poplawski S.E., Li Y., Shu Y., Zhang M., DiMare M.T., Sanford D.G., Lai J.H., Cheng J.D., Alpaugh K.R., Gorrell M.D., et al. Cancerous tissues from human patients contain far higher levels of fibroblast activation protein enzyme activity than corresponding mouse xenografts as revealed using ARI-3144, a new highly specific substrate assay. Cancer Cell 2013, Submitted.
    • (2013) Cancer Cell
    • Poplawski, S.E.1    Li, Y.2    Shu, Y.3    Zhang, M.4    DiMare, M.T.5    Sanford, D.G.6    Lai, J.H.7    Cheng, J.D.8    Alpaugh, K.R.9    Gorrell, M.D.10
  • 62
    • 84865152111 scopus 로고    scopus 로고
    • Activatable near-infrared fluorescent probe for in vivo imaging of fibroblast activation protein-alpha
    • Li J., Chen K., Liu H., Cheng K., Yang M., Zhang J., Cheng JD., Zhang Y., Cheng Z. Activatable near-infrared fluorescent probe for in vivo imaging of fibroblast activation protein-alpha. Bioconjug. Chem. 2012, 23:1704-1711.
    • (2012) Bioconjug. Chem. , vol.23 , pp. 1704-1711
    • Li, J.1    Chen, K.2    Liu, H.3    Cheng, K.4    Yang, M.5    Zhang, J.6    Cheng, J.D.7    Zhang, Y.8    Cheng, Z.9
  • 63
    • 72849125358 scopus 로고    scopus 로고
    • Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice
    • Santos A.M., Jung J., Aziz N., Kissil J.L., Pure E. Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice. J. Clin. Invest. 2010, 119:3613-3626.
    • (2010) J. Clin. Invest. , vol.119 , pp. 3613-3626
    • Santos, A.M.1    Jung, J.2    Aziz, N.3    Kissil, J.L.4    Pure, E.5
  • 66
    • 39149115032 scopus 로고    scopus 로고
    • Editorial: impaired glucose tolerance and incretins in chronic liver disease
    • Gorrell M.D. Editorial: impaired glucose tolerance and incretins in chronic liver disease. J. Gastroenterol. Hepatol. 2008, 23:166-167.
    • (2008) J. Gastroenterol. Hepatol. , vol.23 , pp. 166-167
    • Gorrell, M.D.1
  • 68
    • 0026740736 scopus 로고
    • Altered zonal expression of the CD26 antigen (dipeptidyl peptidase IV) in human cirrhotic liver
    • Matsumoto Y., Bishop G.A., McCaughan G.W. Altered zonal expression of the CD26 antigen (dipeptidyl peptidase IV) in human cirrhotic liver. Hepatology 1992, 15:1048-1053.
    • (1992) Hepatology , vol.15 , pp. 1048-1053
    • Matsumoto, Y.1    Bishop, G.A.2    McCaughan, G.W.3
  • 69
    • 79955654071 scopus 로고    scopus 로고
    • Enhancement of fibrinolysis by inhibiting enzymatic cleavage of precursor alpha2-antiplasmin
    • Lee K.N., Jackson K.W., Christiansen V.J, Dolence E.K., McKee P.A. Enhancement of fibrinolysis by inhibiting enzymatic cleavage of precursor alpha2-antiplasmin. J. Thromb. Haemost. 2011, 9:987-996.
    • (2011) J. Thromb. Haemost. , vol.9 , pp. 987-996
    • Lee, K.N.1    Jackson, K.W.2    Christiansen, V.J.3    Dolence, E.K.4    McKee, P.A.5
  • 71
    • 0036268039 scopus 로고    scopus 로고
    • Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection
    • Levy M.T., McCaughan G.W., Marinos G., Gorrell M.D. Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection. Liver 2002, 22:93-101.
    • (2002) Liver , vol.22 , pp. 93-101
    • Levy, M.T.1    McCaughan, G.W.2    Marinos, G.3    Gorrell, M.D.4
  • 73
    • 79952752537 scopus 로고    scopus 로고
    • Discoidin domain receptor 1: isoform expression and potential functions in cirrhotic human liver
    • Song S., Shackel N.A., Wang X.M., Ajami K., McCaughan G.W., Gorrell M.D. Discoidin domain receptor 1: isoform expression and potential functions in cirrhotic human liver. Am. J. Pathol. 2011, 178:1134-1144.
    • (2011) Am. J. Pathol. , vol.178 , pp. 1134-1144
    • Song, S.1    Shackel, N.A.2    Wang, X.M.3    Ajami, K.4    McCaughan, G.W.5    Gorrell, M.D.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.