Toll-like receptor 4 engagement mediates prolyl endopeptidase release from airway epithelia via exosomes

American Journal of Respiratory Cell and Molecular Biology

Volumn 54, Issue 3, 2016, Pages 359-369

  Szul, Tomasz ^a,b   Bratcher, Preston E ^a,b   Fraser, Kyle B ^c   Kong, Michele ^c,d   Tirouvanziam, Rabindra ^b,e   Ingersoll, Sarah ^e   Sztul, Elizabeth ^c   Rangarajan, Sunil ^a   Blalock, J Edwin ^a,b,d,f   Xu, Xin ^a,b   Gaggar, Amit ^a,b,c,d,f,g  

^a University of Alabama at Birmingham   (United States)

^b Program in Protease and Matrix Biology   (United States)

^c Department of Neurology ^*  (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^g BIRMINGHAM VA MEDICAL CENTER   (United States)

Author keywords

Cystic fibrosis; Exosome; Protease; Pulmonary; Toll like receptor 4

Indexed keywords

LIPOPOLYSACCHARIDE; PROLYL ENDOPEPTIDASE; TOLL LIKE RECEPTOR 4; MITOCHONDRIAL PROTEIN; PREP PROTEIN, HUMAN; SERINE PROTEINASE; TLR4 PROTEIN, HUMAN; TLR4 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME RELEASE; EXOSOME; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN CELL; LUNG FIBROSIS; MOUSE; NONHUMAN; PSEUDOMONAS AERUGINOSA; RESPIRATORY EPITHELIUM; SPUTUM ANALYSIS; ADULT; AGONISTS; ANIMAL; BRONCHUS; C3H MOUSE; CASE CONTROL STUDY; CELL LINE; CYSTIC FIBROSIS; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; EPITHELIUM CELL; GENETIC TRANSFECTION; GENETICS; ISOLATION AND PURIFICATION; KNOCKOUT MOUSE; MALE; METABOLISM; MICROBIOLOGY; RNA INTERFERENCE; SIGNAL TRANSDUCTION; YOUNG ADULT;

ADULT; ANIMALS; BRONCHI; CASE-CONTROL STUDIES; CELL LINE; CYSTIC FIBROSIS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; EXOSOMES; FEMALE; HUMANS; LIPOPOLYSACCHARIDES; MALE; MICE, INBRED C3H; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; PSEUDOMONAS AERUGINOSA; RNA INTERFERENCE; SERINE ENDOPEPTIDASES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSFECTION; YOUNG ADULT;

EID: 84963823800     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2015-0108OC     Document Type: Article

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