메뉴 건너뛰기




Volumn 108, Issue 3, 2013, Pages

Dipeptidyl peptidases in atherosclerosis: Expression and role in macrophage differentiation, activation and apoptosis

Author keywords

Atherosclerosis; DPP4; DPP8; DPP9; DPPIV; Macrophage

Indexed keywords

COMPOUND 1G244; DIPEPTIDYL PEPTIDASE; DIPEPTIDYL PEPTIDASE 8; DIPEPTIDYL PEPTIDASE 9; INTERLEUKIN 6; PEPTIDE HYDROLASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84876284612     PISSN: 03008428     EISSN: 14351803     Source Type: Journal    
DOI: 10.1007/s00395-013-0350-4     Document Type: Article
Times cited : (75)

References (60)
  • 1
    • 0033780088 scopus 로고    scopus 로고
    • Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8
    • 10.1046/j.1432-1327.2000.01617.x 11012666 10.1046/j.1432-1327.2000.01617. x 1:CAS:528:DC%2BD3cXnsVygsLk%3D
    • Abbott CA, Yu DM, Woollatt E, Sutherland GR, McCaughan GW, Gorrell MD (2000) Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8. Eur J Biochem 267:6140-6150. doi: 10.1046/j.1432-1327.2000.01617.x
    • (2000) Eur J Biochem , vol.267 , pp. 6140-6150
    • Abbott, C.A.1    Yu, D.M.2    Woollatt, E.3    Sutherland, G.R.4    McCaughan, G.W.5    Gorrell, M.D.6
  • 2
    • 3042734543 scopus 로고    scopus 로고
    • Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity
    • 10.1016/j.bbaexp.2004.03.010 15245913 10.1016/j.bbaexp.2004.03.010 1:CAS:528:DC%2BD2cXlsFymtr8%3D
    • Ajami K, Abbott CA, McCaughan GW, Gorrell MD (2004) Dipeptidyl peptidase 9 has two forms, a broad tissue distribution, cytoplasmic localization and DPIV-like peptidase activity. Biochim Biophys Acta 1679:18-28. doi: 10.1016/j.bbaexp.2004.03.010
    • (2004) Biochim Biophys Acta , vol.1679 , pp. 18-28
    • Ajami, K.1    Abbott, C.A.2    McCaughan, G.W.3    Gorrell, M.D.4
  • 4
    • 77951151612 scopus 로고    scopus 로고
    • Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4
    • 10.2337/db09-1694 20068138 10.2337/db09-1694 1:CAS:528: DC%2BC3cXltFSmtL0%3D
    • Arakawa M, Mita T, Azuma K, Ebato C, Goto H, Nomiyama T, Fujitani Y, Hirose T, Kawamori R, Watada H (2010) Inhibition of monocyte adhesion to endothelial cells and attenuation of atherosclerotic lesion by a glucagon-like peptide-1 receptor agonist, exendin-4. Diabetes 59:1030-1037. doi: 10.2337/db09-1694
    • (2010) Diabetes , vol.59 , pp. 1030-1037
    • Arakawa, M.1    Mita, T.2    Azuma, K.3    Ebato, C.4    Goto, H.5    Nomiyama, T.6    Fujitani, Y.7    Hirose, T.8    Kawamori, R.9    Watada, H.10
  • 5
    • 33744814340 scopus 로고    scopus 로고
    • Dipeptidyl peptidases 8 and 9: Specificity and molecular characterization compared with dipeptidyl peptidase IV
    • 10.1042/BJ20060079 16475979 10.1042/BJ20060079 1:CAS:528: DC%2BD28XksFGrt70%3D
    • Bjelke JR, Christensen J, Nielsen PF, Branner S, Kanstrup AB, Wagtmann N, Rasmussen HB (2006) Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV. Biochem J 396:391-399. doi: 10.1042/BJ20060079
    • (2006) Biochem J , vol.396 , pp. 391-399
    • Bjelke, J.R.1    Christensen, J.2    Nielsen, P.F.3    Branner, S.4    Kanstrup, A.B.5    Wagtmann, N.6    Rasmussen, H.B.7
  • 6
    • 0014385564 scopus 로고
    • Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
    • 4179068
    • Böyum A (1968) Isolation of mononuclear cells and granulocytes from human blood. Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. Scand J Clin Lab Invest Suppl 97:77-89
    • (1968) Scand J Clin Lab Invest Suppl , vol.97 , pp. 77-89
    • Böyum, A.1
  • 7
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • 10.1016/0003-2697(76)90527-3 942051 10.1016/0003-2697(76)90527-3 1:CAS:528:DyaE28XksVehtrY%3D
    • Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254. doi: 10.1016/0003-2697(76)90527-3
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 8
    • 84861203298 scopus 로고    scopus 로고
    • Clinical implications of cardiovascular preventing pleiotropic effects of dipeptidyl peptidase-4 inhibitors
    • 10.1016/j.amjcard.2012.01.398 22425330 10.1016/j.amjcard.2012.01.398 1:CAS:528:DC%2BC38XktlCis7s%3D
    • Chrysant SG, Chrysant GS (2012) Clinical implications of cardiovascular preventing pleiotropic effects of dipeptidyl peptidase-4 inhibitors. Am J Cardiol 109:1681-1685. doi: 10.1016/j.amjcard.2012.01.398
    • (2012) Am J Cardiol , vol.109 , pp. 1681-1685
    • Chrysant, S.G.1    Chrysant, G.S.2
  • 9
    • 33846818024 scopus 로고    scopus 로고
    • Selective clearance of macrophages in atherosclerotic plaques by the protein synthesis inhibitor cycloheximide
    • 10.1124/jpet.106.113944 17135342 10.1124/jpet.106.113944 1:CAS:528:DC%2BD2sXis1Wgt7k%3D
    • Croons V, Martinet W, Herman AG, Timmermans JP, De Meyer GR (2007) Selective clearance of macrophages in atherosclerotic plaques by the protein synthesis inhibitor cycloheximide. J Pharmacol Exp Ther 320:986-993. doi: 10.1124/jpet.106.113944
    • (2007) J Pharmacol Exp Ther , vol.320 , pp. 986-993
    • Croons, V.1    Martinet, W.2    Herman, A.G.3    Timmermans, J.P.4    De Meyer, G.R.5
  • 10
    • 77649267205 scopus 로고    scopus 로고
    • The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages
    • 10.1371/journal.pone.0008668 20084270 10.1371/journal.pone.0008668
    • Daigneault M, Preston JA, Marriott HM, Whyte MK, Dockrell DH (2010) The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages. PLoS One 5:e8668. doi: 10.1371/journal.pone.0008668
    • (2010) PLoS One , vol.5 , pp. 8668
    • Daigneault, M.1    Preston, J.A.2    Marriott, H.M.3    Whyte, M.K.4    Dockrell, D.H.5
  • 11
    • 0027261263 scopus 로고
    • Antibody binding profile of purified and cell-bound CD26. Designation of BT5/9 and TA5.9 to the CD26 cluster
    • 10.1016/S0171-2985(11)80494-8 8104877 10.1016/S0171-2985(11)80494-8
    • De Meester I, Scharpé S, Vanham G, Bosmans E, Heyligen H, Vanhoof G, Corte G (1993) Antibody binding profile of purified and cell-bound CD26. Designation of BT5/9 and TA5.9 to the CD26 cluster. Immunobiology 188:145-158. doi: 10.1016/S0171-2985(11)80494-8
    • (1993) Immunobiology , vol.188 , pp. 145-158
    • De Meester, I.1    Scharpé, S.2    Vanham, G.3    Bosmans, E.4    Heyligen, H.5    Vanhoof, G.6    Corte, G.7
  • 12
    • 84860153374 scopus 로고    scopus 로고
    • Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaques
    • 10.1007/s00395-012-0269-1 22543675 10.1007/s00395-012-0269-1
    • De Meyer I, Martinet W, Schrijvers DM, Timmermans JP, Bult H, De Meyer GR (2012) Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaques. Basic Res Cardiol 107:269. doi: 10.1007/s00395-012-0269-1
    • (2012) Basic Res Cardiol , vol.107 , pp. 269
    • De Meyer, I.1    Martinet, W.2    Schrijvers, D.M.3    Timmermans, J.P.4    Bult, H.5    De Meyer, G.R.6
  • 13
    • 79951976090 scopus 로고    scopus 로고
    • Inhibition of inositol monophosphatase by lithium chloride induces selective macrophage apoptosis in atherosclerotic plaques
    • 10.1111/j.1476-5381.2010.01152.x 21138421 10.1111/j.1476-5381.2010.01152. x
    • De Meyer I, Martinet W, Van Hove CE, Schrijvers DM, Hoymans VY, Van Vaeck L, Fransen P, Bult H, De Meyer GR (2011) Inhibition of inositol monophosphatase by lithium chloride induces selective macrophage apoptosis in atherosclerotic plaques. Br J Pharmacol 162:1410-1423. doi: 10.1111/j.1476-5381.2010.01152.x
    • (2011) Br J Pharmacol , vol.162 , pp. 1410-1423
    • De Meyer, I.1    Martinet, W.2    Van Hove, C.E.3    Schrijvers, D.M.4    Hoymans, V.Y.5    Van Vaeck, L.6    Fransen, P.7    Bult, H.8    De Meyer, G.R.9
  • 14
    • 78649686908 scopus 로고    scopus 로고
    • Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: A comparative review
    • 10.1111/j.1463-1326.2010.01306.x 21114598 10.1111/j.1463-1326.2010.01306. x 1:CAS:528:DC%2BC3MXlslamsw%3D%3D
    • Deacon CF (2011) Dipeptidyl peptidase-4 inhibitors in the treatment of type 2 diabetes: a comparative review. Diabetes Obes Metab 13:7-18. doi: 10.1111/j.1463-1326.2010.01306.x
    • (2011) Diabetes Obes Metab , vol.13 , pp. 7-18
    • Deacon, C.F.1
  • 15
    • 67649198962 scopus 로고    scopus 로고
    • Enzyme activity and immunohistochemical localization of dipeptidyl peptidase 8 and 9 in male reproductive tissues
    • 10.1369/jhc.2009.952739 19188489 10.1369/jhc.2009.952739 1:CAS:528:DC%2BD1MXmtlGktL0%3D
    • Dubois V, Van Ginneken C, De Cock H, Lambeir AM, Van der Veken P, Augustyns K, Chen X, Scharpé S, De Meester I (2009) Enzyme activity and immunohistochemical localization of dipeptidyl peptidase 8 and 9 in male reproductive tissues. J Histochem Cytochem 57:531-541. doi: 10.1369/jhc.2009. 952739
    • (2009) J Histochem Cytochem , vol.57 , pp. 531-541
    • Dubois, V.1    Van Ginneken, C.2    De Cock, H.3    Lambeir, A.M.4    Van Der Veken, P.5    Augustyns, K.6    Chen, X.7    Scharpé, S.8    De Meester, I.9
  • 16
    • 79955550445 scopus 로고    scopus 로고
    • A user's guide to the encyclopedia of DNA elements
    • ENCODE 10.1371/journal.pbio.1001046 10.1371/journal.pbio.1001046
    • ENCODE (2011) A user's guide to the encyclopedia of DNA elements. PLoS Biol 9:e1001046. doi: 10.1371/journal.pbio.1001046
    • (2011) PLoS Biol , vol.9 , pp. 1001046
  • 17
    • 35348875999 scopus 로고    scopus 로고
    • Transcriptional control of granulocyte and monocyte development
    • 10.1038/sj.onc.1210764 17934488 10.1038/sj.onc.1210764 1:CAS:528:DC%2BD2sXhtFKhsLnO
    • Friedman AD (2007) Transcriptional control of granulocyte and monocyte development. Oncogene 26:6816-6828. doi: 10.1038/sj.onc.1210764
    • (2007) Oncogene , vol.26 , pp. 6816-6828
    • Friedman, A.D.1
  • 18
    • 0033977163 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme expression in human carotid artery atherosclerosis
    • 10.1161/01.HYP.35.1.353 10642324 10.1161/01.HYP.35.1.353 1:CAS:528:DC%2BD3cXpt1agsg%3D%3D
    • Fukuhara M, Geary RL, Diz DI, Gallagher PE, Wilson JA, Glazier SS, Dean RH, Ferrario CM (2000) Angiotensin-converting enzyme expression in human carotid artery atherosclerosis. Hypertension 35:353-359. doi: 10.1161/01.HYP.35.1.353
    • (2000) Hypertension , vol.35 , pp. 353-359
    • Fukuhara, M.1    Geary, R.L.2    Diz, D.I.3    Gallagher, P.E.4    Wilson, J.A.5    Glazier, S.S.6    Dean, R.H.7    Ferrario, C.M.8
  • 19
    • 0027125530 scopus 로고
    • The pathogenesis of coronary artery disease and the acute coronary syndromes (1)
    • 10.1056/NEJM199201233260406 1727977 10.1056/NEJM199201233260406 1:STN:280:DyaK38%2FptlSgtg%3D%3D
    • Fuster V, Badimon L, Badimon JJ, Chesebro JH (1992) The pathogenesis of coronary artery disease and the acute coronary syndromes (1). N Engl J Med 326:242-250. doi: 10.1056/NEJM199201233260406
    • (1992) N Engl J Med , vol.326 , pp. 242-250
    • Fuster, V.1    Badimon, L.2    Badimon, J.J.3    Chesebro, J.H.4
  • 20
    • 70350444734 scopus 로고    scopus 로고
    • The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides
    • 10.1074/jbc.M109.041871 19667070 10.1074/jbc.M109.041871 1:CAS:528:DC%2BD1MXhtFyjsrbN
    • Geiss-Friedlander R, Parmentier N, Moller U, Urlaub H, Van den Eynde BJ, Melchior F (2009) The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides. J Biol Chem 284:27211-27219. doi: 10.1074/jbc.M109.041871
    • (2009) J Biol Chem , vol.284 , pp. 27211-27219
    • Geiss-Friedlander, R.1    Parmentier, N.2    Moller, U.3    Urlaub, H.4    Van Den Eynde, B.J.5    Melchior, F.6
  • 21
    • 79957815398 scopus 로고    scopus 로고
    • Adipocyte-derived lipids increase angiotensin-converting enzyme (ACE) expression and modulate macrophage phenotype
    • 10.1007/s00395-010-0137-9 21116821 10.1007/s00395-010-0137-9 1:CAS:528:DC%2BC3MXhsFGnu7o%3D
    • Kohlstedt K, Trouvain C, Namgaladze D, Fleming I (2011) Adipocyte-derived lipids increase angiotensin-converting enzyme (ACE) expression and modulate macrophage phenotype. Basic Res Cardiol 106:205-215. doi: 10.1007/s00395-010- 0137-9
    • (2011) Basic Res Cardiol , vol.106 , pp. 205-215
    • Kohlstedt, K.1    Trouvain, C.2    Namgaladze, D.3    Fleming, I.4
  • 23
    • 0037787851 scopus 로고    scopus 로고
    • Dipeptidyl-peptidase IV from bench to bedside: An update on structural properties, functions, and clinical aspects of the enzyme DPP IV
    • 10.1080/713609354 12892317 10.1080/713609354 1:CAS:528: DC%2BD3sXmtVWhs70%3D
    • Lambeir AM, Durinx C, Scharpé S, De Meester I (2003) Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV. Crit Rev Clin Lab Sci 40:209-294. doi: 10.1080/713609354
    • (2003) Crit Rev Clin Lab Sci , vol.40 , pp. 209-294
    • Lambeir, A.M.1    Durinx, C.2    Scharpé, S.3    De Meester, I.4
  • 24
    • 56549095221 scopus 로고    scopus 로고
    • DPP4 inhibitors for diabetes - What next?
    • 10.1016/j.bcp.2008.07.029 18755155 10.1016/j.bcp.2008.07.029 1:CAS:528:DC%2BD1cXhsVGgtr%2FK
    • Lambeir AM, Scharpé S, De Meester I (2008) DPP4 inhibitors for diabetes - what next? Biochem Pharmacol 76:1637-1643. doi: 10.1016/j.bcp.2008. 07.029
    • (2008) Biochem Pharmacol , vol.76 , pp. 1637-1643
    • Lambeir, A.M.1    Scharpé, S.2    De Meester, I.3
  • 26
    • 33845984033 scopus 로고    scopus 로고
    • Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8
    • 10.1074/jbc.M603895200 17040910 10.1074/jbc.M603895200 1:CAS:528:DC%2BD28Xht12msr3O
    • Lee HJ, Chen YS, Chou CY, Chien CH, Lin CH, Chang GG, Chen X (2006) Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8. J Biol Chem 281:38653-38662. doi: 10.1074/jbc.M603895200
    • (2006) J Biol Chem , vol.281 , pp. 38653-38662
    • Lee, H.J.1    Chen, Y.S.2    Chou, C.Y.3    Chien, C.H.4    Lin, C.H.5    Chang, G.G.6    Chen, X.7
  • 27
    • 79960554469 scopus 로고    scopus 로고
    • Of mice and men: Neuropeptide y and its receptors are associated with atherosclerotic lesion burden and vulnerability
    • 10.1007/s12265-011-9271-5 21468772 10.1007/s12265-011-9271-5
    • Li L, Najafi AH, Kitlinska JB, Neville R, Laredo J, Epstein SE, Burnett MS, Zukowska Z (2011) Of mice and men: neuropeptide y and its receptors are associated with atherosclerotic lesion burden and vulnerability. J Cardiovasc Transl Res 4:351-362. doi: 10.1007/s12265-011-9271-5
    • (2011) J Cardiovasc Transl Res , vol.4 , pp. 351-362
    • Li, L.1    Najafi, A.H.2    Kitlinska, J.B.3    Neville, R.4    Laredo, J.5    Epstein, S.E.6    Burnett, M.S.7    Zukowska, Z.8
  • 28
    • 0018352691 scopus 로고
    • Studies on dipeptidyl(amino)peptidase IV (glycyl-proline naphthylamidase). II. Blood vessels
    • 10.1007/BF00495663 429202 10.1007/BF00495663 1:CAS:528:DyaE1MXhtlGntLw%3D
    • Lojda Z (1979) Studies on dipeptidyl(amino)peptidase IV (glycyl-proline naphthylamidase). II. Blood vessels. Histochemistry 59:153-166. doi: 10.1007/BF00495663
    • (1979) Histochemistry , vol.59 , pp. 153-166
    • Lojda, Z.1
  • 31
    • 33846816952 scopus 로고    scopus 로고
    • Selective depletion of macrophages in atherosclerotic plaques via macrophage-specific initiation of cell death
    • 10.1016/j.tcm.2006.12.004 17292050 10.1016/j.tcm.2006.12.004 1:CAS:528:DC%2BD2sXhs1Sks7k%3D
    • Martinet W, Verheye S, De Meyer GR (2007) Selective depletion of macrophages in atherosclerotic plaques via macrophage-specific initiation of cell death. Trends Cardiovasc Med 17:69-75. doi: 10.1016/j.tcm.2006.12.004
    • (2007) Trends Cardiovasc Med , vol.17 , pp. 69-75
    • Martinet, W.1    Verheye, S.2    De Meyer, G.R.3
  • 32
    • 79953320085 scopus 로고    scopus 로고
    • Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries
    • 10.1515/BC.2011.002 21194356 10.1515/bc.2011.002 1:CAS:528: DC%2BC3MXkvFCrtr8%3D
    • Matheeussen V, Baerts L, De Meyer G, De Keulenaer G, Van der Veken P, Augustyns K, Dubois V, Scharpe S, De Meester I (2011) Expression and spatial heterogeneity of dipeptidyl peptidases in endothelial cells of conduct vessels and capillaries. Biol Chem 392:189-198. doi: 10.1515/BC.2011.002
    • (2011) Biol Chem , vol.392 , pp. 189-198
    • Matheeussen, V.1    Baerts, L.2    De Meyer, G.3    De Keulenaer, G.4    Van Der Veken, P.5    Augustyns, K.6    Dubois, V.7    Scharpe, S.8    De Meester, I.9
  • 33
    • 84867847993 scopus 로고    scopus 로고
    • Dipeptidyl peptidase IV as a therapeutic target in ischemia-reperfusion injury
    • 10.1016/j.pharmthera.2012.07.012 22850530 10.1016/j.pharmthera.2012.07. 012 1:CAS:528:DC%2BC38Xhtl2kt77K
    • Matheeussen V, Jungraithmayr W, De Meester I (2012) Dipeptidyl peptidase IV as a therapeutic target in ischemia-reperfusion injury. Pharmacol Ther 136:267-282. doi: 10.1016/j.pharmthera.2012.07.012
    • (2012) Pharmacol Ther , vol.136 , pp. 267-282
    • Matheeussen, V.1    Jungraithmayr, W.2    De Meester, I.3
  • 34
    • 84355166409 scopus 로고    scopus 로고
    • Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors
    • 10.1016/j.cca.2011.10.031 22093941 10.1016/j.cca.2011.10.031 1:CAS:528:DC%2BC3MXhs12hu7rO
    • Matheeussen V, Lambeir AM, Jungraithmayr W, Gomez N, Mc Entee K, Van der Veken P, Scharpe S, De Meester I (2012) Method comparison of dipeptidyl peptidase IV activity assays and their application in biological samples containing reversible inhibitors. Clin Chim Acta 413:456-462. doi: 10.1016/j.cca.2011.10.031
    • (2012) Clin Chim Acta , vol.413 , pp. 456-462
    • Matheeussen, V.1    Lambeir, A.M.2    Jungraithmayr, W.3    Gomez, N.4    Mc Entee, K.5    Van Der Veken, P.6    Scharpe, S.7    De Meester, I.8
  • 36
    • 84857903646 scopus 로고    scopus 로고
    • DPP-4 inhibitors and lipids: Systematic review and meta-analysis
    • 10.1007/s12325-011-0088-z 22215383 10.1007/s12325-011-0088-z 1:CAS:528:DC%2BC38XhsV2qtLs%3D
    • Monami M, Lamanna C, Desideri CM, Mannucci E (2012) DPP-4 inhibitors and lipids: systematic review and meta-analysis. Adv Ther 29:14-25. doi: 10.1007/s12325-011-0088-z
    • (2012) Adv Ther , vol.29 , pp. 14-25
    • Monami, M.1    Lamanna, C.2    Desideri, C.M.3    Mannucci, E.4
  • 37
    • 80054110585 scopus 로고    scopus 로고
    • Native incretins prevent the development of atherosclerotic lesions in apolipoprotein e knockout mice
    • 10.1007/s00125-011-2241-2 21786155 10.1007/s00125-011-2241-2 1:CAS:528:DC%2BC3MXhtFGgurjK
    • Nagashima M, Watanabe T, Terasaki M, Tomoyasu M, Nohtomi K, Kim-Kaneyama J, Miyazaki A, Hirano T (2011) Native incretins prevent the development of atherosclerotic lesions in apolipoprotein E knockout mice. Diabetologia 54:2649-2659. doi: 10.1007/s00125-011-2241-2
    • (2011) Diabetologia , vol.54 , pp. 2649-2659
    • Nagashima, M.1    Watanabe, T.2    Terasaki, M.3    Tomoyasu, M.4    Nohtomi, K.5    Kim-Kaneyama, J.6    Miyazaki, A.7    Hirano, T.8
  • 38
    • 0037121086 scopus 로고    scopus 로고
    • Identification and characterization of human DPP9, a novel homologue of dipeptidyl peptidase IV
    • 10.1016/S0378-1119(02)01059-4 12459266 10.1016/S0378-1119(02)01059-4 1:CAS:528:DC%2BD38XovFSks7s%3D
    • Olsen C, Wagtmann N (2002) Identification and characterization of human DPP9, a novel homologue of dipeptidyl peptidase IV. Gene 299:185-193. doi: 10.1016/S0378-1119(02)01059-4
    • (2002) Gene , vol.299 , pp. 185-193
    • Olsen, C.1    Wagtmann, N.2
  • 39
    • 0034743970 scopus 로고    scopus 로고
    • IkappaB kinase-dependent chronic activation of NF-kappaB is necessary for p21(WAF1/Cip1) inhibition of differentiation-induced apoptosis of monocytes
    • 10.1128/MCB.21.6.1930-1941.2001 11238929 10.1128/MCB.21.6.1930-1941.2001 1:CAS:528:DC%2BD3MXjslWht74%3D
    • Pennington KN, Taylor JA, Bren GD, Paya CV (2001) IkappaB kinase-dependent chronic activation of NF-kappaB is necessary for p21(WAF1/Cip1) inhibition of differentiation-induced apoptosis of monocytes. Mol Cell Biol 21:1930-1941. doi: 10.1128/MCB.21.6.1930-1941.2001
    • (2001) Mol Cell Biol , vol.21 , pp. 1930-1941
    • Pennington, K.N.1    Taylor, J.A.2    Bren, G.D.3    Paya, C.V.4
  • 40
    • 84871782137 scopus 로고    scopus 로고
    • A novel SUMO1-specific interacting motif in Dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation
    • 10.1074/jbc.M112.397224 23152501 10.1074/jbc.M112.397224 1:CAS:528:DC%2BC3sXjslCk
    • Pilla E, Moller U, Sauer G, Mattiroli F, Melchior F, Geiss-Friedlander R (2012) A novel SUMO1-specific interacting motif in Dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation. J Biol Chem 287:44320-44329. doi: 10.1074/jbc.M112.397224
    • (2012) J Biol Chem , vol.287 , pp. 44320-44329
    • Pilla, E.1    Moller, U.2    Sauer, G.3    Mattiroli, F.4    Melchior, F.5    Geiss-Friedlander, R.6
  • 42
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • 10.1056/NEJM199901143400207 9887164 10.1056/NEJM199901143400207 1:STN:280:DyaK1M%2FptFSqtQ%3D%3D
    • Ross R (1999) Atherosclerosis - an inflammatory disease. N Engl J Med 340:115-126. doi: 10.1056/NEJM199901143400207
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 43
    • 38649127231 scopus 로고    scopus 로고
    • Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats
    • 10.1369/jhc.7A7319.2007 17967935 10.1369/jhc.7A7319.2007 1:CAS:528:DC%2BD1cXhtlWgtr4%3D
    • Schade J, Stephan M, Schmiedl A, Wagner L, Niestroj AJ, Demuth HU, Frerker N, Klemann C, Raber KA, Pabst R, von Horsten S (2008) Regulation of expression and function of dipeptidyl peptidase 4 (DP4), DP8/9, and DP10 in allergic responses of the lung in rats. J Histochem Cytochem 56:147-155. doi: 10.1369/jhc.7A7319.2007
    • (2008) J Histochem Cytochem , vol.56 , pp. 147-155
    • Schade, J.1    Stephan, M.2    Schmiedl, A.3    Wagner, L.4    Niestroj, A.J.5    Demuth, H.U.6    Frerker, N.7    Klemann, C.8    Raber, K.A.9    Pabst, R.10    Von Horsten, S.11
  • 44
    • 81855222104 scopus 로고    scopus 로고
    • Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis
    • 10.1161/CIRCULATIONAHA.111.041418 22007077 10.1161/CIRCULATIONAHA.111. 041418 1:CAS:528:DC%2BC3MXhsFantrjJ
    • Shah Z, Kampfrath T, Deiuliis JA, Zhong J, Pineda C, Ying Z, Xu X, Lu B, Moffatt-Bruce S, Durairaj R, Sun Q, Mihai G, Maiseyeu A, Rajagopalan S (2011) Long-term dipeptidyl-peptidase 4 inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis. Circulation 124:2338-2349. doi: 10.1161/CIRCULATIONAHA.111.041418
    • (2011) Circulation , vol.124 , pp. 2338-2349
    • Shah, Z.1    Kampfrath, T.2    Deiuliis, J.A.3    Zhong, J.4    Pineda, C.5    Ying, Z.6    Xu, X.7    Lu, B.8    Moffatt-Bruce, S.9    Durairaj, R.10    Sun, Q.11    Mihai, G.12    Maiseyeu, A.13    Rajagopalan, S.14
  • 45
    • 58149301489 scopus 로고    scopus 로고
    • Intensive glycemic control and the prevention of cardiovascular events: Implications of the ACCORD, ADVANCE, and VA Diabetes Trials: A position statement of the American Diabetes Association and a Scientific Statement of the American College of Cardiology Foundation and the American Heart Association
    • 10.1016/j.jacc.2008.10.008 19147051 10.1016/j.jacc.2008.10.008
    • Skyler JS, Bergenstal R, Bonow RO, Buse J, Deedwania P, Gale EA, Howard BV, Kirkman MS, Kosiborod M, Reaven P, Sherwin RS (2009) Intensive glycemic control and the prevention of cardiovascular events: implications of the ACCORD, ADVANCE, and VA Diabetes Trials: a position statement of the American Diabetes Association and a Scientific Statement of the American College of Cardiology Foundation and the American Heart Association. J Am Coll Cardiol 53:298-304. doi: 10.1016/j.jacc.2008.10.008
    • (2009) J Am Coll Cardiol , vol.53 , pp. 298-304
    • Skyler, J.S.1    Bergenstal, R.2    Bonow, R.O.3    Buse, J.4    Deedwania, P.5    Gale, E.A.6    Howard, B.V.7    Kirkman, M.S.8    Kosiborod, M.9    Reaven, P.10    Sherwin, R.S.11
  • 46
    • 0032917708 scopus 로고    scopus 로고
    • Selective inhibition of apoptosis by TPA-induced differentiation of U937 leukemic cells
    • 10.1038/sj.cdd.4400499 10381626 10.1038/sj.cdd.4400499 1:CAS:528:DyaK1MXivFSqsrs%3D
    • Sordet O, Bettaieb A, Bruey JM, Eymin B, Droin N, Ivarsson M, Garrido C, Solary E (1999) Selective inhibition of apoptosis by TPA-induced differentiation of U937 leukemic cells. Cell Death Differ 6:351-361. doi: 10.1038/sj.cdd. 4400499
    • (1999) Cell Death Differ , vol.6 , pp. 351-361
    • Sordet, O.1    Bettaieb, A.2    Bruey, J.M.3    Eymin, B.4    Droin, N.5    Ivarsson, M.6    Garrido, C.7    Solary, E.8
  • 47
    • 84878913837 scopus 로고    scopus 로고
    • Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide's anti-leukemic activity
    • doi: 10.1038/leu.2013.9
    • Spagnuolo PA, Hurren R, Gronda M, Maclean N, Datti A, Basheer A, Lin FH, Wang X, Wrana J, Schimmer AD (2013) Inhibition of intracellular dipeptidyl peptidases 8 and 9 enhances parthenolide's anti-leukemic activity. Leukemia. doi: 10.1038/leu.2013.9
    • (2013) Leukemia
    • Spagnuolo, P.A.1    Hurren, R.2    Gronda, M.3    MacLean, N.4    Datti, A.5    Basheer, A.6    Lin, F.H.7    Wang, X.8    Wrana, J.9
  • 48
    • 80051785333 scopus 로고    scopus 로고
    • DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice
    • 10.1097/FJC.0b013e31821e5626 21558879 10.1097/FJC.0b013e31821e5626 1:CAS:528:DC%2BC3MXhtVWjtLbK
    • Ta NN, Schuyler CA, Li Y, Lopes-Virella MF, Huang Y (2011) DPP-4 (CD26) inhibitor alogliptin inhibits atherosclerosis in diabetic apolipoprotein E-deficient mice. J Cardiovasc Pharmacol 58:157-166. doi: 10.1097/FJC. 0b013e31821e5626
    • (2011) J Cardiovasc Pharmacol , vol.58 , pp. 157-166
    • Ta, N.N.1    Schuyler, C.A.2    Li, Y.3    Lopes-Virella, M.F.4    Huang, Y.5
  • 49
    • 33645891172 scopus 로고    scopus 로고
    • Cytokines in atherosclerosis: Pathogenic and regulatory pathways
    • 10.1152/physrev.00024.2005 16601268 10.1152/physrev.00024.2005 1:CAS:528:DC%2BD28Xktlylu7g%3D
    • Tedgui A, Mallat Z (2006) Cytokines in atherosclerosis: pathogenic and regulatory pathways. Physiol Rev 86:515-581. doi: 10.1152/physrev.00024.2005
    • (2006) Physiol Rev , vol.86 , pp. 515-581
    • Tedgui, A.1    Mallat, Z.2
  • 50
    • 84862128306 scopus 로고    scopus 로고
    • Effects of PKF275-055, a dipeptidyl peptidase-4 inhibitor, on the development of atherosclerotic lesions in apolipoprotein E-null mice
    • 10.1016/j.metabol.2011.11.011 10.1016/j.metabol.2011.11.011 1:CAS:528:DC%2BC38XosVaksbk%3D
    • Terasaki M, Nagashima M, Watanabe T, Nohtomi K, Mori Y, Miyazaki A, Hirano T (2012) Effects of PKF275-055, a dipeptidyl peptidase-4 inhibitor, on the development of atherosclerotic lesions in apolipoprotein E-null mice. Metab 61:974-977. doi: 10.1016/j.metabol.2011.11.011
    • (2012) Metab , vol.61 , pp. 974-977
    • Terasaki, M.1    Nagashima, M.2    Watanabe, T.3    Nohtomi, K.4    Mori, Y.5    Miyazaki, A.6    Hirano, T.7
  • 51
    • 84860204551 scopus 로고    scopus 로고
    • Cardiovascular biology of the incretin system
    • 10.1210/er.2011-1052 22323472 10.1210/er.2011-1052 1:CAS:528: DC%2BC38XnsVOrsLc%3D
    • Ussher JR, Drucker DJ (2012) Cardiovascular biology of the incretin system. Endocr Rev 33:187-215. doi: 10.1210/er.2011-1052
    • (2012) Endocr Rev , vol.33 , pp. 187-215
    • Ussher, J.R.1    Drucker, D.J.2
  • 52
    • 0031978804 scopus 로고    scopus 로고
    • Transcription factors that regulate monocyte/macrophage differentiation
    • 9544570 1:CAS:528:DyaK1cXisVSns7w%3D
    • Valledor AF, Borras FE, Cullell-Young M, Celada A (1998) Transcription factors that regulate monocyte/macrophage differentiation. J Leukoc Biol 63:405-417
    • (1998) J Leukoc Biol , vol.63 , pp. 405-417
    • Valledor, A.F.1    Borras, F.E.2    Cullell-Young, M.3    Celada, A.4
  • 53
    • 80051862999 scopus 로고    scopus 로고
    • Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): Is DPP8-selectivity an attainable goal?
    • 10.1021/jm200383j 21711053 10.1021/jm200383j
    • Van Goethem S, Matheeussen V, Joossens J, Lambeir AM, Chen X, De Meester I, Haemers A, Augustyns K, Van der Veken P (2011) Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal? J Med Chem 54:5737-5746. doi: 10.1021/jm200383j
    • (2011) J Med Chem , vol.54 , pp. 5737-5746
    • Van Goethem, S.1    Matheeussen, V.2    Joossens, J.3    Lambeir, A.M.4    Chen, X.5    De Meester, I.6    Haemers, A.7    Augustyns, K.8    Van Der Veken, P.9
  • 54
    • 33646455658 scopus 로고    scopus 로고
    • Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation
    • 10.1189/jlb.0105015 16330536 10.1189/jlb.0105015 1:CAS:528: DC%2BD28Xht12rtLc%3D
    • Verreck FA, de Boer T, Langenberg DM, van der Zanden L, Ottenhoff TH (2006) Phenotypic and functional profiling of human proinflammatory type-1 and anti-inflammatory type-2 macrophages in response to microbial antigens and IFN-gamma- and CD40L-mediated costimulation. J Leukoc Biol 79:285-293. doi: 10.1189/jlb.0105015
    • (2006) J Leukoc Biol , vol.79 , pp. 285-293
    • Verreck, F.A.1    De Boer, T.2    Langenberg, D.M.3    Van Der Zanden, L.4    Ottenhoff, T.H.5
  • 55
    • 0034019601 scopus 로고    scopus 로고
    • Lessons from sudden coronary death: A comprehensive morphological classification scheme for atherosclerotic lesions
    • 10.1161/01.ATV.20.5.1262 10807742 10.1161/01.ATV.20.5.1262 1:STN:280:DC%2BD3c3ntVCntA%3D%3D
    • Virmani R, Kolodgie FD, Burke AP, Farb A, Schwartz SM (2000) Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 20:1262-1275. doi: 10.1161/01.ATV.20.5.1262
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1262-1275
    • Virmani, R.1    Kolodgie, F.D.2    Burke, A.P.3    Farb, A.4    Schwartz, S.M.5
  • 57
    • 77956226226 scopus 로고    scopus 로고
    • Emerging roles of SUMO modification in arthritis
    • 10.1016/j.gene.2010.07.003 20627123 10.1016/j.gene.2010.07.003 1:CAS:528:DC%2BC3cXhtFWiu7zN
    • Yan D, Davis FJ, Sharrocks AD, Im HJ (2010) Emerging roles of SUMO modification in arthritis. Gene 466:1-15. doi: 10.1016/j.gene.2010.07.003
    • (2010) Gene , vol.466 , pp. 1-15
    • Yan, D.1    Davis, F.J.2    Sharrocks, A.D.3    Im, H.J.4
  • 58
    • 84856702326 scopus 로고    scopus 로고
    • The potential effects of anti-diabetic medications on myocardial ischemia-reperfusion injury
    • 10.1007/s00395-011-0216-6 21892746 10.1007/s00395-011-0216-6 1:CAS:528:DC%2BC3MXhsFOnsL7L
    • Ye Y, Perez-Polo JR, Aguilar D, Birnbaum Y (2011) The potential effects of anti-diabetic medications on myocardial ischemia-reperfusion injury. Basic Res Cardiol 106:925-952. doi: 10.1007/s00395-011-0216-6
    • (2011) Basic Res Cardiol , vol.106 , pp. 925-952
    • Ye, Y.1    Perez-Polo, J.R.2    Aguilar, D.3    Birnbaum, Y.4
  • 60
    • 76349097770 scopus 로고    scopus 로고
    • The dipeptidyl peptidase IV family in cancer and cell biology
    • 10.1111/j.1742-4658.2009.07526.x 20074209 10.1111/j.1742-4658.2009.07526. x 1:CAS:528:DC%2BC3cXivVSmtr8%3D
    • Yu DM, Yao TW, Chowdhury S, Nadvi NA, Osborne B, Church WB, McCaughan GW, Gorrell MD (2010) The dipeptidyl peptidase IV family in cancer and cell biology. FEBS J 277:1126-1144. doi: 10.1111/j.1742-4658.2009.07526.x
    • (2010) FEBS J , vol.277 , pp. 1126-1144
    • Yu, D.M.1    Yao, T.W.2    Chowdhury, S.3    Nadvi, N.A.4    Osborne, B.5    Church, W.B.6    McCaughan, G.W.7    Gorrell, M.D.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.