Structural and kinetic analysis of the substrate specificity of human fibroblast activation protein α

Journal of Biological Chemistry

Volumn 280, Issue 20, 2005, Pages 19441-19444

  Aertgeerts, Kathleen ^a   Levin, Irena ^a   Shi, Lihong ^a   Snell, Gyorgy P ^a   Jennings, Andy ^a   Prasad, G Sridhar ^a   Zhang, Yanming ^a   Kraus, Michelle L ^a   Salakian, Shant ^a   Sridhar, Vandana ^a   Wijnands, Robert ^a   Tennant, Mike G ^a  

^a Takeda San Diego Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BIOMEDICAL ENGINEERING; CELLS; ENZYME KINETICS; HUMAN ENGINEERING; TUMORS;

FIBROBLASTS; KINETIC ANALYSIS; METASTASIS; TUMOR GROWTH;

PROTEINS;

APOENZYME; COUMARIN; DIPEPTIDYL PEPTIDASE IV; HYDROLASE; MUTANT PROTEIN; PROTEINASE; SEPRASE; DIPEPTIDE; FLUORESCENT DYE; GELATINASE; MEMBRANE PROTEIN; RECOMBINANT PROTEIN; SERINE PROTEINASE;

ACIDITY; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; DIMERIZATION; ENZYME ACTIVE SITE; ENZYME GLYCOSYLATION; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; EXTRACELLULAR MATRIX; HYDROLYSIS; METASTASIS; POINT MUTATION; PRIORITY JOURNAL; TUMOR GROWTH; CHEMICAL STRUCTURE; CHEMISTRY; COMPARATIVE STUDY; GENETICS; HUMAN; IN VITRO STUDY; KINETICS; METABOLISM; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

AMINO ACID MOTIFS; ANTIGENS, CD26; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIPEPTIDES; FLUORESCENT DYES; GELATINASES; HUMANS; KINETICS; MEMBRANE PROTEINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; SUBSTRATE SPECIFICITY;

EID: 21244503095     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C500092200     Document Type: Article

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