Fibroblast activation protein (FAP) accelerates collagen degradation and clearance from lungs in mice

Journal of Biological Chemistry

Volumn 291, Issue 15, 2016, Pages 8070-8089

  Fan, Ming Hui ^a   Zhu, Qiang ^b   Li, Hui Hua ^a   Ra, Hyun Jeong ^c   Majumdar, Sonali ^d   Gulick, Dexter L ^a   Jerome, Jacob A ^a   Madsen, Daniel H ^e   Christofidou Solomidou, Melpo ^c   Speicher, David W ^d   Bachovchin, William W ^f   Feghali Bostwick, Carol ^g   Puré, Ellen ^c  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d WISTAR INSTITUTE   (United States)

^e NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^f TUFTS UNIVERSITY   (United States)

^g MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL ORGANS; CELL CULTURE; CELL MEMBRANES; CHEMICAL ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FIBROBLASTS; HYDROXYPROLINE; MAMMALS; PEPTIDES; PROTEINS; TISSUE;

COLLAGEN DEGRADATIONS; EXTRACELLULAR MATRICES; HYDROXYPROLINE CONTENT; IDIOPATHIC PULMONARY FIBROSIS; LUNG TRANSPLANTATION; MATRIX METALLOPROTEINASES; PROTEOLYTIC PROCESSING; THORACIC IRRADIATIONS;

COLLAGEN;

BLEOMYCIN; COLLAGEN; COLLAGEN RECEPTOR; COLLAGEN RECEPTOR ENDO180; FIBROBLAST ACTIVATION PROTEIN; HYDROXYPROLINE; MATRIX METALLOPROTEINASE; SEPRASE; UNCLASSIFIED DRUG; GELATINASE; MEMBRANE PROTEIN; MESSENGER RNA; SERINE PROTEINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN CLEARANCE; COLLAGEN DEGRADATION; COLLAGEN METABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; EXTRACELLULAR MATRIX; FEMALE; FIBROSING ALVEOLITIS; IN VITRO STUDY; INTERNALIZATION; LUNG INJURY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; ANIMAL; C57BL MOUSE; CELL CULTURE; FIBROBLAST; GENE DELETION; GENETICS; HUMAN; LUNG; LUNG FIBROSIS; METABOLISM; PATHOLOGY; PROTEIN DEGRADATION; UPREGULATION;

ANIMALS; CELLS, CULTURED; COLLAGEN; FIBROBLASTS; GELATINASES; GENE DELETION; HUMANS; LUNG; MALE; MATRIX METALLOPROTEINASES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; PROTEOLYSIS; PULMONARY FIBROSIS; RNA, MESSENGER; SERINE ENDOPEPTIDASES; UP-REGULATION;

EID: 84964678926     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.701433     Document Type: Article

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