Cepip: Context-dependent epigenomic weighting for prioritization of regulatory variants and disease-associated genes

Genome Biology

Volumn 18, Issue 1, 2017, Pages

  Li, Mulin Jun ^a,c,f   Li, Miaoxin ^b,c,d   Liu, Zipeng ^c   Yan, Bin ^c   Pan, Zhicheng ^c,e   Huang, Dandan ^a   Liang, Qian ^a   Ying, Dingge ^c   Xu, Feng ^c   Yao, Hongcheng ^c   Wang, Panwen ^g   Kocher, Jean Pierre A ^g   Xia, Zhengyuan ^c   Sham, Pak Chung ^c   Liu, Jun S ^f   Wang, Junwen ^g,h  

^a TIANJIN MEDICAL UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

^d UNIVERSITY OF HONG KONG   (Hong Kong)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f HARVARD UNIVERSITY   (United States)

^g MAYO CLINIC   (United States)

^h ARIZONA STATE UNIVERSITY   (United States)

Author keywords

Cell type specific; Disease susceptible gene; Epigenome; Regulatory variant; Variant prioritization

Indexed keywords

ARTICLE; CELL SPECIFICITY; CHROMATIN; CONTROLLED STUDY; DISEASE ASSOCIATION; DNA METHYLATION; EPIGENETICS; GENE CONTROL; GENE EXPRESSION PROFILING; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; HISTONE METHYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; PHENOTYPE; PREDICTION; PROBABILITY; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; SOFTWARE; ANTIBODY SPECIFICITY; CLUSTER ANALYSIS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; METABOLISM; PROCEDURES;

CHROMATIN; HISTONE;

CHROMATIN; CLUSTER ANALYSIS; EPIGENESIS, GENETIC; EPIGENOMICS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; HISTONES; HUMANS; ORGAN SPECIFICITY; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI;

EID: 85015699072     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-017-1177-3     Document Type: Article

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