-
1
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, et al. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proceedings of the National Academy of Sciences 106: 9362–9367.
-
(2009)
Proceedings of the National Academy of Sciences
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
-
2
-
-
84890310753
-
Fine-scale mapping of the fgfr2 breast cancer risk locus: putative functional variants differentially bind foxa1 and e2f1
-
Meyer KB, OReilly M, Michailidou K, Carlebur S, Edwards SL, et al. (2013) Fine-scale mapping of the fgfr2 breast cancer risk locus: putative functional variants differentially bind foxa1 and e2f1. The American Journal of Human Genetics 93: 1046–1060.
-
(2013)
The American Journal of Human Genetics
, vol.93
, pp. 1046-1060
-
-
Meyer, K.B.1
Oreilly, M.2
Michailidou, K.3
Carlebur, S.4
Edwards, S.L.5
-
3
-
-
84878451270
-
Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with tert expression
-
Kote-Jarai Z, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Dadaev T, et al. (2013) Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with tert expression. Human molecular genetics 22: 2520–2528.
-
(2013)
Human molecular genetics
, vol.22
, pp. 2520-2528
-
-
Kote-Jarai, Z.1
Saunders, E.J.2
Leongamornlert, D.A.3
Tymrakiewicz, M.4
Dadaev, T.5
-
4
-
-
84875996758
-
Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained
-
Wu Y, Waite LL, Jackson AU, Sheu WH, Buyske S, et al. (2013) Trans-ethnic fine-mapping of lipid loci identifies population-specific signals and allelic heterogeneity that increases the trait variance explained. PLoS genetics 9: e1003379.
-
(2013)
PLoS genetics
, vol.9
, pp. e1003379
-
-
Wu, Y.1
Waite, L.L.2
Jackson, A.U.3
Sheu, W.H.4
Buyske, S.5
-
5
-
-
84870502629
-
Bayesian refinement of association signals for 14 loci in 3 common diseases
-
Maller JB, McVean G, Byrnes J, Vukcevic D, Palin K, et al. (2012) Bayesian refinement of association signals for 14 loci in 3 common diseases. Nature genetics 44: 1294–1301.
-
(2012)
Nature genetics
, vol.44
, pp. 1294-1301
-
-
Maller, J.B.1
McVean, G.2
Byrnes, J.3
Vukcevic, D.4
Palin, K.5
-
6
-
-
84884623924
-
Re-ranking sequencing variants in the post-gwas era for accurate causal variant identification
-
Faye LL, Machiela MJ, Kraft P, Bull SB, Sun L, (2013) Re-ranking sequencing variants in the post-gwas era for accurate causal variant identification. PLoS genetics 9: e1003609.
-
(2013)
PLoS genetics
, vol.9
, pp. e1003609
-
-
Faye, L.L.1
Machiela, M.J.2
Kraft, P.3
Bull, S.B.4
Sun, L.5
-
8
-
-
84895868553
-
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
-
Type AGEN, Type SA, Consortium DS, Type MA, Consortium DM, et al. (2014) Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nature genetics 46: 234–244.
-
(2014)
Nature genetics
, vol.46
, pp. 234-244
-
-
Type, A.G.E.N.1
Type, S.A.2
Consortium, D.S.3
Type, M.A.4
Consortium, D.M.5
-
9
-
-
84887058596
-
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
-
Consortium IMSG, et al. (2013) Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nature genetics.
-
(2013)
Nature genetics
-
-
Consortium, I.M.S.G.1
-
10
-
-
84898723939
-
Joint analysis of functional genomic data and genome-wide association studies of 18 human traits
-
Pickrell JK, (2014) Joint analysis of functional genomic data and genome-wide association studies of 18 human traits. The American Journal of Human Genetics 94: 559–573.
-
(2014)
The American Journal of Human Genetics
, vol.94
, pp. 559-573
-
-
Pickrell, J.K.1
-
11
-
-
84856321864
-
Dissecting the regulatory architecture of gene expression qtls
-
Gaffney DJ, Veyrieras JB, Degner JF, Pique-Regi R, Pai AA, et al. (2012) Dissecting the regulatory architecture of gene expression qtls. Genome Biol 13: R7.
-
(2012)
Genome Biol
, vol.13
, pp. R7
-
-
Gaffney, D.J.1
Veyrieras, J.B.2
Degner, J.F.3
Pique-Regi, R.4
Pai, A.A.5
-
12
-
-
84868225071
-
A novel algorithm for simultaneous snp selection in high-dimensional genome-wide association studies
-
Zuber V, Silva APD, Strimmer K, (2012) A novel algorithm for simultaneous snp selection in high-dimensional genome-wide association studies. BMC bioinformatics 13: 284.
-
(2012)
BMC bioinformatics
, vol.13
, pp. 284
-
-
Zuber, V.1
Silva, A.P.D.2
Strimmer, K.3
-
13
-
-
84862252240
-
Reprioritizing genetic associations in hit regions using lasso-based resample model averaging
-
Valdar W, Sabourin J, Nobel A, Holmes CC, (2012) Reprioritizing genetic associations in hit regions using lasso-based resample model averaging. Genetic epidemiology 36: 451–462.
-
(2012)
Genetic epidemiology
, vol.36
, pp. 451-462
-
-
Valdar, W.1
Sabourin, J.2
Nobel, A.3
Holmes, C.C.4
-
14
-
-
82955223524
-
Bayesian variable selection regression for genome-wide association studies and other large-scale problems
-
Guan Y, Stephens M, et al. (2011) Bayesian variable selection regression for genome-wide association studies and other large-scale problems. The Annals of Applied Statistics 5: 1780–1815.
-
(2011)
The Annals of Applied Statistics
, vol.5
, pp. 1780-1815
-
-
Guan, Y.1
Stephens, M.2
-
15
-
-
34547622688
-
Imputation-based analysis of association studies: candidate regions and quantitative traits
-
Servin B, Stephens M, (2007) Imputation-based analysis of association studies: candidate regions and quantitative traits. PLoS genetics 3: e114.
-
(2007)
PLoS genetics
, vol.3
, pp. e114
-
-
Servin, B.1
Stephens, M.2
-
16
-
-
59249086642
-
Learning a prior on regulatory potential from eqtl data
-
Lee SI, Dudley AM, Drubin D, Silver PA, Krogan NJ, et al. (2009) Learning a prior on regulatory potential from eqtl data. PLoS genetics 5: e1000358.
-
(2009)
PLoS genetics
, vol.5
, pp. e1000358
-
-
Lee, S.I.1
Dudley, A.M.2
Drubin, D.3
Silver, P.A.4
Krogan, N.J.5
-
17
-
-
84887281556
-
Integrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for il-2 signaling genes in type 1 diabetes, and cytokine signaling genes in crohn's disease
-
Carbonetto P, Stephens M, (2013) Integrated enrichment analysis of variants and pathways in genome-wide association studies indicates central role for il-2 signaling genes in type 1 diabetes, and cytokine signaling genes in crohn's disease. PLoS genetics 9: e1003770.
-
(2013)
PLoS genetics
, vol.9
, pp. e1003770
-
-
Carbonetto, P.1
Stephens, M.2
-
18
-
-
84865790047
-
An integrated encyclopedia of dna elements in the human genome
-
Consortium EP, et al. (2012) An integrated encyclopedia of dna elements in the human genome. Nature 489: 57–74.
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
Consortium, E.P.1
-
19
-
-
84865822182
-
Systematic localization of common disease-associated variation in regulatory dna
-
Maurano MT, Humbert R, Rynes E, Thurman RE, Haugen E, et al. (2012) Systematic localization of common disease-associated variation in regulatory dna. Science 337: 1190–1195.
-
(2012)
Science
, vol.337
, pp. 1190-1195
-
-
Maurano, M.T.1
Humbert, R.2
Rynes, E.3
Thurman, R.E.4
Haugen, E.5
-
20
-
-
84889580677
-
Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases
-
Trynka G, Raychaudhuri S, (2013) Using chromatin marks to interpret and localize genetic associations to complex human traits and diseases. Current opinion in genetics & development 23: 635–641.
-
(2013)
Current opinion in genetics & development
, vol.23
, pp. 635-641
-
-
Trynka, G.1
Raychaudhuri, S.2
-
21
-
-
84878697229
-
Systematic functional regulatory assessment of disease-associated variants
-
Karczewski KJ, Dudley JT, Kukurba KR, Chen R, Butte AJ, et al. (2013) Systematic functional regulatory assessment of disease-associated variants. Proceedings of the National Academy of Sciences 110: 9607–9612.
-
(2013)
Proceedings of the National Academy of Sciences
, vol.110
, pp. 9607-9612
-
-
Karczewski, K.J.1
Dudley, J.T.2
Kukurba, K.R.3
Chen, R.4
Butte, A.J.5
-
22
-
-
84873086126
-
Chromatin marks identify critical cell types for fine mapping complex trait variants
-
Trynka G, Sandor C, Han B, Xu H, Stranger BE, et al. (2013) Chromatin marks identify critical cell types for fine mapping complex trait variants. Nature genetics 45: 124–130.
-
(2013)
Nature genetics
, vol.45
, pp. 124-130
-
-
Trynka, G.1
Sandor, C.2
Han, B.3
Xu, H.4
Stranger, B.E.5
-
23
-
-
84908140383
-
-
bioRxiv
-
Gusev A, Lee SH, Neale BM, Trynka G, Vilhjalmsson BJ, et al. (2014) Regulatory variants explain much more heritability than coding variants across 11 common diseases. bioRxiv.
-
(2014)
Regulatory variants explain much more heritability than coding variants across 11 common diseases
-
-
Gusev, A.1
Lee, S.H.2
Neale, B.M.3
Trynka, G.4
Vilhjalmsson, B.J.5
-
24
-
-
64549113646
-
Fgfr2 variants and breast cancer risk: fine-scale mapping using african american studies and analysis of chromatin conformation
-
Udler MS, Meyer KB, Pooley KA, Karlins E, Struewing JP, et al. (2009) Fgfr2 variants and breast cancer risk: fine-scale mapping using african american studies and analysis of chromatin conformation. Human molecular genetics 18: 1692–1703.
-
(2009)
Human molecular genetics
, vol.18
, pp. 1692-1703
-
-
Udler, M.S.1
Meyer, K.B.2
Pooley, K.A.3
Karlins, E.4
Struewing, J.P.5
-
25
-
-
82255192188
-
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease
-
Trynka G, Hunt KA, Bockett NA, Romanos J, Mistry V, et al. (2011) Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nature genetics 43: 1193–1201.
-
(2011)
Nature genetics
, vol.43
, pp. 1193-1201
-
-
Trynka, G.1
Hunt, K.A.2
Bockett, N.A.3
Romanos, J.4
Mistry, V.5
-
26
-
-
84888231843
-
Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: Hla and non-hla effects
-
Patsopoulos NA, Barcellos LF, Hintzen RQ, Schaefer C, van Duijn CM, et al. (2013) Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: Hla and non-hla effects. PLoS genetics 9: e1003926.
-
(2013)
PLoS genetics
, vol.9
, pp. e1003926
-
-
Patsopoulos, N.A.1
Barcellos, L.F.2
Hintzen, R.Q.3
Schaefer, C.4
Van Duijn, C.M.5
-
27
-
-
84866924593
-
Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis
-
Liu JZ, Almarri MA, Gaffney DJ, Mells GF, Jostins L, et al. (2012) Dense fine-mapping study identifies new susceptibility loci for primary biliary cirrhosis. Nature genetics 44: 1137–1141.
-
(2012)
Nature genetics
, vol.44
, pp. 1137-1141
-
-
Liu, J.Z.1
Almarri, M.A.2
Gaffney, D.J.3
Mells, G.F.4
Jostins, L.5
-
28
-
-
77949773445
-
Itpa gene variants protect against anaemia in patients treated for chronic hepatitis c
-
Fellay J, Thompson AJ, Ge D, Gumbs CE, Urban TJ, et al. (2010) Itpa gene variants protect against anaemia in patients treated for chronic hepatitis c. Nature 464: 405–408.
-
(2010)
Nature
, vol.464
, pp. 405-408
-
-
Fellay, J.1
Thompson, A.J.2
Ge, D.3
Gumbs, C.E.4
Urban, T.J.5
-
29
-
-
38049023107
-
Hierarchical bayes prioritization of marker associations from a genome-wide association scan for further investigation
-
Lewinger JP, Conti DV, Baurley JW, Triche TJ, Thomas DC, (2007) Hierarchical bayes prioritization of marker associations from a genome-wide association scan for further investigation. Genetic epidemiology 31: 871–882.
-
(2007)
Genetic epidemiology
, vol.31
, pp. 871-882
-
-
Lewinger, J.P.1
Conti, D.V.2
Baurley, J.W.3
Triche, T.J.4
Thomas, D.C.5
-
30
-
-
84887187386
-
Integrative variable selection via bayesian model uncertainty
-
Quintana M, Conti D, (2013) Integrative variable selection via bayesian model uncertainty. Statistics in medicine 32: 4938–4953.
-
(2013)
Statistics in medicine
, vol.32
, pp. 4938-4953
-
-
Quintana, M.1
Conti, D.2
-
31
-
-
77954209295
-
Evaluating the power to discriminate between highly correlated snps in genetic association studies
-
Udler MS, Tyrer J, Easton DF, (2010) Evaluating the power to discriminate between highly correlated snps in genetic association studies. Genetic epidemiology 34: 463–468.
-
(2010)
Genetic epidemiology
, vol.34
, pp. 463-468
-
-
Udler, M.S.1
Tyrer, J.2
Easton, D.F.3
-
33
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, et al. (2010) Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466: 707–713.
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
Musunuru, K.2
Smith, A.V.3
Edmondson, A.C.4
Stylianou, I.M.5
-
34
-
-
84921782559
-
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
-
btu416
-
Pasaniuc B, Zaitlen N, Shi H, Bhatia G, Gusev A, et al. (2014) Fast and accurate imputation of summary statistics enhances evidence of functional enrichment. Bioinformatics: btu416.
-
(2014)
Bioinformatics
-
-
Pasaniuc, B.1
Zaitlen, N.2
Shi, H.3
Bhatia, G.4
Gusev, A.5
-
35
-
-
66349103652
-
Rapid and accurate multiple testing correction and power estimation for millions of correlated markers
-
Han B, Kang HM, Eskin E, (2009) Rapid and accurate multiple testing correction and power estimation for millions of correlated markers. PLoS genetics 5: e1000456.
-
(2009)
PLoS genetics
, vol.5
, pp. e1000456
-
-
Han, B.1
Kang, H.M.2
Eskin, E.3
-
36
-
-
36749079336
-
So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests
-
Conneely KN, Boehnke M, (2007) So many correlated tests, so little time! Rapid adjustment of P values for multiple correlated tests. American journal of human genetics 81: 1158–1168.
-
(2007)
American journal of human genetics
, vol.81
, pp. 1158-1168
-
-
Conneely, K.N.1
Boehnke, M.2
-
37
-
-
73149100820
-
Leveraging genetic variability across populations for the identification of causal variants
-
Zaitlen N, Pasaniuc B, Gur T, Ziv E, Halperin E, (2010) Leveraging genetic variability across populations for the identification of causal variants. American journal of human genetics 86: 23–33.
-
(2010)
American journal of human genetics
, vol.86
, pp. 23-33
-
-
Zaitlen, N.1
Pasaniuc, B.2
Gur, T.3
Ziv, E.4
Halperin, E.5
-
38
-
-
33646887390
-
On the limited memory bfgs method for large scale optimization
-
Liu DC, Nocedal J, (1989) On the limited memory bfgs method for large scale optimization. Mathematical programming 45: 503–528.
-
(1989)
Mathematical programming
, vol.45
, pp. 503-528
-
-
Liu, D.C.1
Nocedal, J.2
-
41
-
-
84862832570
-
Conditional and joint multiple-snp analysis of gwas summary statistics identifies additional variants influencing complex traits
-
Yang J, Ferreira T, Morris AP, Medland SE, Madden PA, et al. (2012) Conditional and joint multiple-snp analysis of gwas summary statistics identifies additional variants influencing complex traits. Nature genetics 44: 369–375.
-
(2012)
Nature genetics
, vol.44
, pp. 369-375
-
-
Yang, J.1
Ferreira, T.2
Morris, A.P.3
Medland, S.E.4
Madden, P.A.5
-
42
-
-
84865755978
-
The accessible chromatin landscape of the human genome
-
Thurman RE, Rynes E, Humbert R, Vierstra J, Maurano MT, et al. (2012) The accessible chromatin landscape of the human genome. Nature 489: 75–82.
-
(2012)
Nature
, vol.489
, pp. 75-82
-
-
Thurman, R.E.1
Rynes, E.2
Humbert, R.3
Vierstra, J.4
Maurano, M.T.5
-
43
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich et al TM, (2010) Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466: 707–713.
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich Et Al, T.M.1
-
44
-
-
0037390308
-
Linkage disequilibrium patterns of the human genome across populations
-
Shifman S, Kuypers J, Kokoris M, Yakir B, Darvasi A, (2003) Linkage disequilibrium patterns of the human genome across populations. Human molecular genetics 12: 771–776.
-
(2003)
Human molecular genetics
, vol.12
, pp. 771-776
-
-
Shifman, S.1
Kuypers, J.2
Kokoris, M.3
Yakir, B.4
Darvasi, A.5
|