Lysosomal adaptation: How cells respond to lysosomotropic compounds

PLoS ONE

Volumn 12, Issue 3, 2017, Pages

  Lu, Shuyan ^a   Sung, Tae ^a   Lin, Nianwei ^b   Abraham, Robert T ^a   Jessen, Bart A ^a  

^a PFIZER INC   (United States)

^b IXCells Biotechnologies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMITRIPTYLINE; CALCIUM; CATHEPSIN B; CATHEPSIN D; CHEMICAL COMPOUND; CHLOROQUINE; CHLORPROMAZINE; DIMEBON; FLUOXETINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; IMIPRAMINE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MICROPHTHALMIA ASSOCIATED TRANSCRIPTION FACTOR; OPSIN; PHOSPHOLIPID; SEQUESTOSOME 1; TAMOXIFEN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR E3; TRANSCRIPTION FACTOR EB; UNCLASSIFIED DRUG; VERAPAMIL; SQSTM1 PROTEIN, HUMAN;

ADAPTATION; ARTICLE; BIOGENESIS; CALCIUM SIGNALING; CELL ACTIVATION; CELL STRESS; CONTROLLED STUDY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LYSOSOMAL STRESS; LYSOSOME; PH; SIGNAL TRANSDUCTION; STAINING; CELL LINE; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; METABOLISM; PHYSIOLOGY; RETINAL PIGMENT EPITHELIUM;

ADAPTATION, PHYSIOLOGICAL; CELL LINE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; OPSINS; RETINAL PIGMENT EPITHELIUM; SEQUESTOSOME-1 PROTEIN;

EID: 85015616099     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0173771     Document Type: Article

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