Latrepirdine (dimebon), a potential alzheimer therapeutic, regulates autophagy and neuropathology in an alzheimer mouse model

Autophagy

Volumn 9, Issue 4, 2013, Pages 617-618

  Steele, John W ^a   Gandy, Sam ^b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer; Amyloid; Dimebon; Latrepirdine; Lysosome; Macroautophagy; Neurodegeneration; Presenilin; Synuclein; Therapeutics

Indexed keywords

AMYLOID PRECURSOR PROTEIN; AUTOPHAGY PROTEIN 5; DIMEBON; MAMMALIAN TARGET OF RAPAMYCIN; ALPHA SYNUCLEIN; AMYLOID; AMYLOID BETA PROTEIN; INDOLE DERIVATIVE; PRESENILIN; SYNUCLEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BEHAVIOR DISORDER; BRAIN TISSUE; CELL CULTURE; DRUG MECHANISM; LONG TERM CARE; MOUSE; NEUROPATHOLOGY; NONHUMAN; PROTEIN METABOLISM; WILD TYPE; ALZHEIMER; ANIMAL; DISEASE MODEL; DRUG EFFECT; HUMAN; LYSOSOME; MACROAUTOPHAGY; METABOLISM; NERVE CELL; NERVE DEGENERATION; PATHOLOGY; SECRETION (PROCESS); THERAPY; TRANSGENIC MOUSE;

ALZHEIMER; AMYLOID; DIMEBON; LATREPIRDINE; LYSOSOME; MACROAUTOPHAGY; NEURODEGENERATION; PRESENILIN; SYNUCLEIN; THERAPEUTICS;

ALPHA-SYNUCLEIN; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; AUTOPHAGY; DISEASE MODELS, ANIMAL; HUMANS; INDOLES; MICE; MICE, TRANSGENIC; NEURONS;

EID: 84877333097     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.23487     Document Type: Article

References (0)