Identification and Inhibitory Mechanism of Angiotensin I-Converting Enzyme Inhibitory Peptides Derived from Bovine Hemoglobin

Protein Journal

Volumn 36, Issue 3, 2017, Pages 166-173

  Wang, Ying ^a   Jiang, Yiqun ^a   Yin, Yongguang ^a   Liu, Jiyun ^a   Ding, Long ^a   Liu, Jingbo ^a   Zhang, Ting ^a  

^a JILIN UNIVERSITY   (China)

Author keywords

ACE inhibitory peptide; Bovine hemoglobin; Inhibitory mechanism; Molecular docking

Indexed keywords

CHLORIDE ION; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HEMOGLOBIN; PEPTIDE; ZINC ION; ACE PROTEIN, HUMAN;

AMINO ACID SEQUENCE; ARTICLE; DIGESTION; DRUG IDENTIFICATION; ENERGY; ENZYME INHIBITION; HYDROGEN BOND; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MOLECULAR DOCKING; MOLECULAR INTERACTION; PROTEIN CONFORMATION; ANIMAL; BOVINE; CHEMISTRY; HUMAN;

ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; CATTLE; HEMOGLOBINS; HUMANS; MOLECULAR DOCKING SIMULATION; PEPTIDES; PEPTIDYL-DIPEPTIDASE A;

EID: 85015607657     PISSN: 15723887     EISSN: 18758355     Source Type: Journal    
DOI: 10.1007/s10930-017-9708-z     Document Type: Article

References (43)

1. Hernandez-Ledesma B, Del Mar Contreras M, Recio I (2011) Antihypertensive peptides: production, bioavailability and incorporation into foods. Adv Colloid Interface Sci 165(1):23–35
2. Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK, He J (2005) Global burden of hypertension: analysis of worldwide data. Lancet 365:213–217
3. Nwankwo T, Yoon S, Burt V, Gu Q (2013) Hypertension among adults in the United States: National Health and Nutrition Examination Survey, 2011–2012. NCHS Data Brief 133:1–8
4. Hanif K, Bid HK, Konwar R (2010) Reinventing the ACE inhibitors: some old and new implications of ACE Inhibition. Hypertens Res 33(1):11–21
5. Watermeyer JM (2008) Structural determinants of the domain-selectivity of novel inhibitors of human testis angiotensin-converting enzyme[D]. Medical Biochemistry, University of Cape Town
6. Li GH, Le GW, Shi YH, Shrestha S (2004) Angiotensin I-converting enzyme inhibitory peptides derived from food proteins and their physiological and pharmacological effects. Nutr Res 24(7):469–486
7. Fleming I (2006) Signaling by the angiotensin-converting enzyme. Circ Res 98(7):887–896
8. Papakyriakou A, Spyroulias GA, Sturrock ED, Manessi-Zoupa E, Cordopatis P (2007) Simulated interactions between angiotensin-converting enzyme and substrate gonadotropin-releasing hormone novel insights into domain selectivity. Biochem 46:8753–8765
9. Zhou M, Du K, Ji P, Feng W (2012) Molecular mechanism of the interactions between inhibitory tripeptides and angiotensin-converting enzyme. Biophys Chem 168–169:60–66
10. Douglas RG, Sharma RK, Masuyer G, Lubbe L, Zamora I, Acharya KR, Chibale K, Sturrock ED (2014) Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors. Clin Sci 126(4):305–313
11. Liu J, Yu Z, Zhao W, Lin S, Wang E, Zhang Y, Hao H, Wang Z, Chen F (2010) Isolation and identification of angiotensin-converting enzyme inhibitory peptides from egg white protein hydrolysates. Food Chem 122(4):1159–1163
12. Yu Z, Zhao W, Liu J, Lu J, Chen F (2011) QIGLF, a novel angiotensin I-converting enzyme-inhibitory peptide from egg white protein. J Sci Food Agric 91(5):921–926
13. Tomatsu M, Shimakage A, Shinbo M, Yamada S, Takahashi S (2013) Novel angiotensin I-converting enzyme inhibitory peptides derived from soya milk. Food Chem 136(2):612–616
14. Gouda KGM, Gowda LR, Rao AGA, Prakash V (2006) Angiotensin I-converting enzyme inhibitory peptide derived from glycinin, the 11S globulin of soybean (Glycine max). J Agric Food Chem 54(13):4568–4573
15. Asoodeh A, Haghighi L, Chamani J, Ansari-Ogholbeyk MA, Mojallal-Tabatabaei Z, Lagzian M (2014) Potential angiotensin I converting enzyme inhibitory peptides from gluten hydrolysate: biochemical characterization and molecular docking study. J Cereal Sci 60(1):92–98
16. Qu W, Ma H, Zhao W, Pan Z (2013) ACE-inhibitory peptides production from defatted wheat germ protein by continuous coupling of enzymatic hydrolysis and membrane separation: modeling and experimental studies. Chem Eng J 226:139–145
17. Escudero E, Sentandreu MA, Arihara K, Toldrá F (2010) Angiotensin I-converting enzyme inhibitory peptides generated from in vitro gastrointestinal digestion of pork meat. J Agric Food Chem 58(5):2895–2901
18. Escudero E, Toldra F, Sentandreu MA, Nishimura H, Arihara K (2012) Antihypertensive activity of peptides identified in the in vitro gastrointestinal digest of pork meat. Meat Sci 91(3):382–384
19. Toldra F, Aristoy MC, Mora L, Reig M (2012) Innovations in value-addition of edible meat by-products. Meat Sci 92(3):290–296
20. Zhang T, Nie S, Liu B, Yu Y, Zhang Y, Liu J (2015) Activity prediction and molecular mechanism of bovine blood derived angiotensin I-converting enzyme inhibitory peptides. PLoS ONE 10(3):e0119598
21. Álvarez C, García V, Rendueles M, Díaz M (2012) Functional properties of isolated porcine blood proteins modified by Maillard’s reaction. Food Hydrocoll 28:267–274
22. Yu Z, Liu B, Zhao W, Yin Y, Liu J, Chen F (2012) Primary and secondary structure of novel ACE-inhibitory peptides from egg white protein. Food Chem 133(2):315–322
23. Morris GM, Goodsell DS, Halliday RS, Huey R, Hart WE, Belew RK, Olson AJ (2015) Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function. J Comput Chem 19(14):1639–1662
24. Chen D, Menche G, Power TD, Sower L, Peterson JW, Schein CH (2007) Accounting for ligand-bound metal ions in docking small molecules on adenylyl cyclase toxins. Proteins 67(3):593–605
25. Natesh R, Schwager SL, Sturrock ED, Acharya KR (2003) Crystal structure of the human angiotensin-converting enzyme-lisinopril complex. Nature 421(30):551–554
26. Jiang Z, Tian B, Brodkorb A, Huo G (2010) Production, analysis and in vivo evaluation of novel angiotensin-I-converting enzyme inhibitory peptides from bovine casein. Food Chem 123(3):779–786
27. Pijlanto-Leppala A, Koskinen P, Pililola K, Tupasela T, Korhonen H (2000) Angiotensin I-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides. J Dairy Res 67(01):53–64
28. Yu Y, Hu J, Miyaguchi Y, Bai X, Du Y, Lin B (2006) Isolation and characterization of angiotensin I-converting enzyme inhibitory peptides derived from porcine hemoglobin. Peptides 27:2950–2956
29. Donkor ON, Henriksson A, Singh TK, Vasiljevic T, P Shah N (2007) ACE-inhibitory activity of probiotic yoghurt. Int Dairy J 17(11):1321–1331
30. Matsui T, Li CH, Osajima Y (1999) Preparation and characterization of novel bioactive peptides responsible for angiotensin I-converting enzyme inhibition from wheat germ. J Pept Sci 5(7):289–297
31. Guang C, Phillips RD (2009) Plant food-derived Angiotensin I converting enzyme inhibitory peptides. J Agric Food Chem 57(12):5113–5120
32. Ngo DH, Ryu B, Kim SK (2014) Active peptides from skate (Okamejei kenojei) skin gelatin diminish angiotensin-I converting enzyme activity and intracellular free radical-mediated oxidation. Food Chem 143:246–255
33. Iwaniak A, Minkiewicz P, Darewicz M (2014) Food-originating ACE inhibitors, including antihypertensive peptides, as preventive food components in blood pressure reduction. Compr Rev Food Sci Food Saf 13(2):114–134
34. Fournié-Zaluski MC, Chaillet P, Soroca-Lucas E, Marçais-Collado H, Costentin J, Roques BP (1983) New carboxyalkyl inhibitors of brain enkephalinase: synthesis, biological activity, and analgesic properties. J Med Chem 26:60–65
35. Wu J, Aluko RE, Muir AD (2008) Purification of angiotensin I-converting enzyme-inhibitory peptides from the enzymatic hydrolysate of defatted canola meal. Food Chem 111:942–950
36. Eto Y, Ito T, Nishioka S (1998) Angiotensin I converting enzyme-inhibitory dipeptides in an anlkaline protease hydrolysate of whey protein. J Jpn Soc Food Sci 51:355–359
37. Chen JR, Okada T, Muramoto K, Suetsuna K, Yang SC (2002) Identification of Angiotensin I-converting enzyme inhibitory peptides derived from the peptic digest of soybean protein. J Food Biochem 26(6):543–554
38. Kuba M, Tanaka K, Tawata S, Takeda Y, Yasuda M (2003) Angiotensin I-converting enzyme inhibitory peptides isolated from tofuyo fermented soybean food. Biosci Biotechnol Biochem 67(6):1278–1283
39. Suetsuna K, Chen J (2001) Identification of antihypertensive peptides from peptic digest of two microalage, chlorella vugaris and apirulina platensis. Mar Biotechnol 3:305–309
40. Cushman DW, Ondetti MA (1999) Design of angiotensin converting enzyme inhibitors. Nat Med 5(10):1110–1112
41. Ondetti M, Rubin B, Cushman D (1977) Design of specific inhibitors of angiotensin-converting enzyme: new class of orally active antihypertensive agents. Science 196(4288):441–445
42. Lee SH, Qian ZJ, Kim SK (2010) A novel angiotensin I converting enzyme inhibitory peptide from tuna frame protein hydrolysate and its antihypertensive effect in spontaneously hypertensive rats. Food Chem 118(1):96–102
43. Ni H, Li L, Liu G, Hu SQ (2012) Inhibition mechanism and model of an angiotensin I-converting enzyme (ACE)-inhibitory hexapeptide from yeast (Saccharomyces cerevisiae). PLoS ONE 7(5):e37077