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Volumn 198, Issue 3, 2017, Pages 1130-1141

IL-10 receptor signaling is essential for TR1 cell function in vivo

Author keywords

[No Author keywords available]

Indexed keywords

ENHANCED GREEN FLUORESCENT PROTEIN; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR ALPHA; MITOGEN ACTIVATED PROTEIN KINASE P38; RED FLUORESCENT PROTEIN; TRANSCRIPTION FACTOR FOXP3; INTERLEUKIN 10 RECEPTOR; STAT3 PROTEIN; STAT3 PROTEIN, MOUSE;

EID: 85014699932     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1601045     Document Type: Conference Paper
Times cited : (90)

References (69)
  • 3
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kühn, R., J. Löhler, D. Rennick, K. Rajewsky, and W. Müller. 1993. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75: 263-274.
    • (1993) Cell , vol.75 , pp. 263-274
    • Kühn, R.1    Löhler, J.2    Rennick, D.3    Rajewsky, K.4    Müller, W.5
  • 5
    • 81155160952 scopus 로고    scopus 로고
    • Type 1 regulatory T cells (Tr1) in autoimmunity
    • Pot, C., L. Apetoh, and V. K. Kuchroo. 2011. Type 1 regulatory T cells (Tr1) in autoimmunity. Semin. Immunol. 23: 202-208.
    • (2011) Semin. Immunol. , vol.23 , pp. 202-208
    • Pot, C.1    Apetoh, L.2    Kuchroo, V.K.3
  • 6
    • 0036883901 scopus 로고    scopus 로고
    • Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora
    • Cong, Y., C. T. Weaver, A. Lazenby, and C. O. Elson. 2002. Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora. J. Immunol. 169: 6112-6119.
    • (2002) J. Immunol. , vol.169 , pp. 6112-6119
    • Cong, Y.1    Weaver, C.T.2    Lazenby, A.3    Elson, C.O.4
  • 9
    • 83055173312 scopus 로고    scopus 로고
    • Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation
    • Gagliani, N., S. Gregori, T. Jofra, A. Valle, A. Stabilini, D. M. Rothstein, M. Atkinson, M. G. Roncarolo, and M. Battaglia. 2011. Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation. PLoS One 6: e28434.
    • (2011) PLoS One , vol.6 , pp. e28434
    • Gagliani, N.1    Gregori, S.2    Jofra, T.3    Valle, A.4    Stabilini, A.5    Rothstein, D.M.6    Atkinson, M.7    Roncarolo, M.G.8    Battaglia, M.9
  • 12
    • 82755197890 scopus 로고    scopus 로고
    • Clinical perspectives for regulatory T cells in transplantation tolerance
    • Hippen, K. L., J. L. Riley, C. H. June, and B. R. Blazar. 2011. Clinical perspectives for regulatory T cells in transplantation tolerance. Semin. Immunol. 23: 462-468.
    • (2011) Semin. Immunol. , vol.23 , pp. 462-468
    • Hippen, K.L.1    Riley, J.L.2    June, C.H.3    Blazar, B.R.4
  • 14
    • 79954504851 scopus 로고    scopus 로고
    • Clinical tolerance in allogeneic hematopoietic stem cell transplantation
    • Roncarolo, M. G., S. Gregori, B. Lucarelli, F. Ciceri, and R. Bacchetta. 2011. Clinical tolerance in allogeneic hematopoietic stem cell transplantation. Immunol. Rev. 241: 145-163.
    • (2011) Immunol. Rev. , vol.241 , pp. 145-163
    • Roncarolo, M.G.1    Gregori, S.2    Lucarelli, B.3    Ciceri, F.4    Bacchetta, R.5
  • 16
    • 79957576097 scopus 로고    scopus 로고
    • Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells
    • Magnani, C. F., G. Alberigo, R. Bacchetta, G. Serafini, M. Andreani, M. G. Roncarolo, and S. Gregori. 2011. Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells. Eur. J. Immunol. 41: 1652-1662.
    • (2011) Eur. J. Immunol. , vol.41 , pp. 1652-1662
    • Magnani, C.F.1    Alberigo, G.2    Bacchetta, R.3    Serafini, G.4    Andreani, M.5    Roncarolo, M.G.6    Gregori, S.7
  • 19
    • 49149119535 scopus 로고    scopus 로고
    • Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells
    • Batten, M., N. M. Kljavin, J. Li, M. J. Walter, F. J. de Sauvage, and N. Ghilardi. 2008. Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells. J. Immunol. 180: 2752-2756.
    • (2008) J. Immunol. , vol.180 , pp. 2752-2756
    • Batten, M.1    Kljavin, N.M.2    Li, J.3    Walter, M.J.4    De Sauvage, F.J.5    Ghilardi, N.6
  • 22
    • 84923088133 scopus 로고    scopus 로고
    • An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction
    • [Published erratum appears in 2015 Nat. Commun. DOI: 10.1038/ncomms8657.]
    • Zhu, C., K. Sakuishi, S. Xiao, Z. Sun, S. Zaghouani, G. Gu, C. Wang, D. J. Tan, C. Wu, M. Rangachari, et al. 2015. An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction. [Published erratum appears in 2015 Nat. Commun. DOI: 10.1038/ncomms8657.] Nat. Commun. DOI: 10.1038/ncomms7072.
    • (2015) Nat. Commun.
    • Zhu, C.1    Sakuishi, K.2    Xiao, S.3    Sun, Z.4    Zaghouani, S.5    Gu, G.6    Wang, C.7    Tan, D.J.8    Wu, C.9    Rangachari, M.10
  • 28
    • 36248970702 scopus 로고    scopus 로고
    • Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells
    • Fitzgerald, D. C., G. X. Zhang, M. El-Behi, Z. Fonseca-Kelly, H. Li, S. Yu, C. J. Saris, B. Gran, B. Ciric, and A. Rostami. 2007. Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells. Nat. Immunol. 8: 1372-1379.
    • (2007) Nat. Immunol. , vol.8 , pp. 1372-1379
    • Fitzgerald, D.C.1    Zhang, G.X.2    El-Behi, M.3    Fonseca-Kelly, Z.4    Li, H.5    Yu, S.6    Saris, C.J.7    Gran, B.8    Ciric, B.9    Rostami, A.10
  • 30
    • 84860259163 scopus 로고    scopus 로고
    • Regulatory T-cell therapy for inflammatory bowel disease: More questions than answers
    • Himmel, M. E., Y. Yao, P. C. Orban, T. S. Steiner, and M. K. Levings. 2012. Regulatory T-cell therapy for inflammatory bowel disease: more questions than answers. Immunology 136: 115-122.
    • (2012) Immunology , vol.136 , pp. 115-122
    • Himmel, M.E.1    Yao, Y.2    Orban, P.C.3    Steiner, T.S.4    Levings, M.K.5
  • 33
    • 0029981103 scopus 로고    scopus 로고
    • Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain
    • Weber-Nordt, R. M., J. K. Riley, A. C. Greenlund, K. W. Moore, J. E. Darnell, and R. D. Schreiber. 1996. Stat3 recruitment by two distinct ligand-induced, tyrosine-phosphorylated docking sites in the interleukin-10 receptor intracellular domain. J. Biol. Chem. 271: 27954-27961.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27954-27961
    • Weber-Nordt, R.M.1    Riley, J.K.2    Greenlund, A.C.3    Moore, K.W.4    Darnell, J.E.5    Schreiber, R.D.6
  • 35
    • 34548656855 scopus 로고    scopus 로고
    • Signaling pathways downstream of patternrecognition receptors and their cross talk
    • Lee, M. S., and Y. J. Kim. 2007. Signaling pathways downstream of patternrecognition receptors and their cross talk. Annu. Rev. Biochem. 76: 447-480.
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 447-480
    • Lee, M.S.1    Kim, Y.J.2
  • 36
    • 33845453812 scopus 로고    scopus 로고
    • Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse
    • Kamanaka, M., S. T. Kim, Y. Y. Wan, F. S. Sutterwala, M. Lara-Tejero, J. E. Galán, E. Harhaj, and R. A. Flavell. 2006. Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse. Immunity 25: 941-952.
    • (2006) Immunity , vol.25 , pp. 941-952
    • Kamanaka, M.1    Kim, S.T.2    Wan, Y.Y.3    Sutterwala, F.S.4    Lara-Tejero, M.5    Galán, J.E.6    Harhaj, E.7    Flavell, R.A.8
  • 38
    • 17044430217 scopus 로고    scopus 로고
    • Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter
    • Wan, Y. Y., and R. A. Flavell. 2005. Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter. Proc. Natl. Acad. Sci. USA 102: 5126-5131.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 5126-5131
    • Wan, Y.Y.1    Flavell, R.A.2
  • 40
    • 34447280907 scopus 로고    scopus 로고
    • High resolution colonoscopy in live mice
    • Becker, C., M. C. Fantini, and M. F. Neurath. 2006. High resolution colonoscopy in live mice. Nat. Protoc. 1: 2900-2904.
    • (2006) Nat. Protoc. , vol.1 , pp. 2900-2904
    • Becker, C.1    Fantini, M.C.2    Neurath, M.F.3
  • 42
    • 77956538422 scopus 로고    scopus 로고
    • Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway
    • Gregori, S., D. Tomasoni, V. Pacciani, M. Scirpoli, M. Battaglia, C. F. Magnani, E. Hauben, and M. G. Roncarolo. 2010. Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway. Blood 116: 935-944.
    • (2010) Blood , vol.116 , pp. 935-944
    • Gregori, S.1    Tomasoni, D.2    Pacciani, V.3    Scirpoli, M.4    Battaglia, M.5    Magnani, C.F.6    Hauben, E.7    Roncarolo, M.G.8
  • 44
    • 60849139395 scopus 로고    scopus 로고
    • GOrilla: A tool for discovery and visualization of enriched GO terms in ranked gene lists
    • Eden, E., R. Navon, I. Steinfeld, D. Lipson, and Z. Yakhini. 2009. GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists. BMC Bioinformatics 10: 48.
    • (2009) BMC Bioinformatics , vol.10 , pp. 48
    • Eden, E.1    Navon, R.2    Steinfeld, I.3    Lipson, D.4    Yakhini, Z.5
  • 45
    • 41549107522 scopus 로고    scopus 로고
    • Cytokine signaling modules in inflammatory responses
    • O'Shea, J. J., and P. J. Murray. 2008. Cytokine signaling modules in inflammatory responses. Immunity 28: 477-487.
    • (2008) Immunity , vol.28 , pp. 477-487
    • O'Shea, J.J.1    Murray, P.J.2
  • 46
    • 69249083836 scopus 로고    scopus 로고
    • Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells
    • Pot, C., H. Jin, A. Awasthi, S. M. Liu, C. Y. Lai, R. Madan, A. H. Sharpe, C. L. Karp, S. C. Miaw, I. C. Ho, and V. K. Kuchroo. 2009. Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells. J. Immunol. 183: 797-801.
    • (2009) J. Immunol. , vol.183 , pp. 797-801
    • Pot, C.1    Jin, H.2    Awasthi, A.3    Liu, S.M.4    Lai, C.Y.5    Madan, R.6    Sharpe, A.H.7    Karp, C.L.8    Miaw, S.C.9    Ho, I.C.10    Kuchroo, V.K.11
  • 47
    • 70350464351 scopus 로고    scopus 로고
    • Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis
    • Murai, M., O. Turovskaya, G. Kim, R. Madan, C. L. Karp, H. Cheroutre, and M. Kronenberg. 2009. Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis. Nat. Immunol. 10: 1178-1184.
    • (2009) Nat. Immunol. , vol.10 , pp. 1178-1184
    • Murai, M.1    Turovskaya, O.2    Kim, G.3    Madan, R.4    Karp, C.L.5    Cheroutre, H.6    Kronenberg, M.7
  • 50
    • 34248374256 scopus 로고    scopus 로고
    • Activation of MAP kinase p38 is critical for the cell-cycle-controlled suppressor function of regulatory T cells
    • Adler, H. S., S. Kubsch, E. Graulich, S. Ludwig, J. Knop, and K. Steinbrink. 2007. Activation of MAP kinase p38 is critical for the cell-cycle-controlled suppressor function of regulatory T cells. Blood 109: 4351-4359.
    • (2007) Blood , vol.109 , pp. 4351-4359
    • Adler, H.S.1    Kubsch, S.2    Graulich, E.3    Ludwig, S.4    Knop, J.5    Steinbrink, K.6
  • 51
    • 70350639037 scopus 로고    scopus 로고
    • The inhibition of JNK and p38 MAPKs downregulates IL-10 and differentially affects c-Jun gene expression in human monocytes
    • Dobreva, Z. G., L. D. Miteva, and S. A. Stanilova. 2009. The inhibition of JNK and p38 MAPKs downregulates IL-10 and differentially affects c-Jun gene expression in human monocytes. Immunopharmacol. Immunotoxicol. 31: 195-201.
    • (2009) Immunopharmacol. Immunotoxicol. , vol.31 , pp. 195-201
    • Dobreva, Z.G.1    Miteva, L.D.2    Stanilova, S.A.3
  • 52
    • 33846471668 scopus 로고    scopus 로고
    • The role of p38 mitogenactivated protein kinase in regulating interleukin-10 gene expression in Burkitt's lymphoma cell lines
    • Horie, K., M. Ohashi, Y. Satoh, and T. Sairenji. 2007. The role of p38 mitogenactivated protein kinase in regulating interleukin-10 gene expression in Burkitt's lymphoma cell lines. Microbiol. Immunol. 51: 149-161.
    • (2007) Microbiol. Immunol. , vol.51 , pp. 149-161
    • Horie, K.1    Ohashi, M.2    Satoh, Y.3    Sairenji, T.4
  • 53
    • 0035958007 scopus 로고    scopus 로고
    • The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages
    • (PubMed)
    • Ma, W., W. Lim, K. Gee, S. Aucoin, D. Nandan, M. Kozlowski, F. Diaz-Mitoma, and A. Kumar. 2001. The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophages. J. Biol. Chem. 276: 13664-13674 (PubMed).
    • (2001) J. Biol. Chem. , vol.276 , pp. 13664-13674
    • Ma, W.1    Lim, W.2    Gee, K.3    Aucoin, S.4    Nandan, D.5    Kozlowski, M.6    Diaz-Mitoma, F.7    Kumar, A.8
  • 54
    • 34147163337 scopus 로고    scopus 로고
    • Expression of IL-10 in Th memory lymphocytes is conditional on IL-12 or IL-4, unless the IL-10 gene is imprinted by GATA-3
    • Chang, H. D., C. Helbig, L. Tykocinski, S. Kreher, J. Koeck, U. Niesner, and A. Radbruch. 2007. Expression of IL-10 in Th memory lymphocytes is conditional on IL-12 or IL-4, unless the IL-10 gene is imprinted by GATA-3. Eur. J. Immunol. 37: 807-817.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 807-817
    • Chang, H.D.1    Helbig, C.2    Tykocinski, L.3    Kreher, S.4    Koeck, J.5    Niesner, U.6    Radbruch, A.7
  • 55
    • 68649116551 scopus 로고    scopus 로고
    • Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose
    • Saraiva, M., J. R. Christensen, M. Veldhoen, T. L. Murphy, K. M. Murphy, and A. O'Garra. 2009. Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose. Immunity 31: 209-219.
    • (2009) Immunity , vol.31 , pp. 209-219
    • Saraiva, M.1    Christensen, J.R.2    Veldhoen, M.3    Murphy, T.L.4    Murphy, K.M.5    O'Garra, A.6
  • 58
    • 0033527443 scopus 로고    scopus 로고
    • Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogenactivated protein kinase
    • Kumar, S., M. S. Jiang, J. L. Adams, and J. C. Lee. 1999. Pyridinylimidazole compound SB 203580 inhibits the activity but not the activation of p38 mitogenactivated protein kinase. Biochem. Biophys. Res. Commun. 263: 825-831.
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 825-831
    • Kumar, S.1    Jiang, M.S.2    Adams, J.L.3    Lee, J.C.4
  • 64
    • 32644473626 scopus 로고    scopus 로고
    • Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance
    • Battaglia, M., A. Stabilini, E. Draghici, S. Gregori, C. Mocchetti, E. Bonifacio, and M. G. Roncarolo. 2006. Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance. Diabetes 55: 40-49.
    • (2006) Diabetes , vol.55 , pp. 40-49
    • Battaglia, M.1    Stabilini, A.2    Draghici, E.3    Gregori, S.4    Mocchetti, C.5    Bonifacio, E.6    Roncarolo, M.G.7
  • 66
    • 2942685507 scopus 로고    scopus 로고
    • Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells
    • Akdis, M., J. Verhagen, A. Taylor, F. Karamloo, C. Karagiannidis, R. Crameri, S. Thunberg, G. Deniz, R. Valenta, H. Fiebig, et al. 2004. Immune responses in healthy and allergic individuals are characterized by a fine balance between allergen-specific T regulatory 1 and T helper 2 cells. J. Exp. Med. 199: 1567-1575.
    • (2004) J. Exp. Med. , vol.199 , pp. 1567-1575
    • Akdis, M.1    Verhagen, J.2    Taylor, A.3    Karamloo, F.4    Karagiannidis, C.5    Crameri, R.6    Thunberg, S.7    Deniz, G.8    Valenta, R.9    Fiebig, H.10
  • 67
    • 84958548312 scopus 로고    scopus 로고
    • Tr1 cells and the counter-regulation of immunity: Natural mechanisms and therapeutic applications
    • (PubMed)
    • Roncarolo, M. G., S. Gregori, R. Bacchetta, and M. Battaglia. 2014. Tr1 cells and the counter-regulation of immunity: natural mechanisms and therapeutic applications. Curr. Top. Microbiol. Immunol. 380: 39-68 (PubMed).
    • (2014) Curr. Top. Microbiol. Immunol. , vol.380 , pp. 39-68
    • Roncarolo, M.G.1    Gregori, S.2    Bacchetta, R.3    Battaglia, M.4
  • 68
    • 0036127426 scopus 로고    scopus 로고
    • Heme oxygenase-1 mediates the antiinflammatory effect of interleukin-10 in mice
    • Lee, T. S., and L. Y. Chau. 2002. Heme oxygenase-1 mediates the antiinflammatory effect of interleukin-10 in mice. Nat. Med. 8: 240-246.
    • (2002) Nat. Med. , vol.8 , pp. 240-246
    • Lee, T.S.1    Chau, L.Y.2


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