The p38 Mitogen-activated Kinase Pathway Regulates the Human Interleukin-10 Promoter via the Activation of Sp1 Transcription Factor in Lipopolysaccharide-stimulated Human Macrophages

Journal of Biological Chemistry

Volumn 276, Issue 17, 2001, Pages 13664-13674

  Ma, Wei ^b   Lim, Wilfred ^a   Gee, Katrina ^a   Aucoin, Susan ^b   Nandan, Devki ^c   Kozlowski, Maya ^d   Diaz Mitoma, Francisco ^a,b   Kumar, Ashok ^a,b  

^a UNIVERSITY OF OTTAWA   (Canada)

^b CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d HEALTH CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; DNA; IMMUNOLOGY; PROTEINS;

TRANSCRIPTION FACTOR;

BIOCHEMISTRY;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; COMPLEMENTARY DNA; DNA; INTERLEUKIN 10; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; TRANSCRIPTION FACTOR SP1; 4-(4-FLUOROPHENYL)-2-(4-HYDROXYPHENYL)-5-(4-PYRIDYL)IMIDAZOLE; ARABIDOPSIS PROTEIN; DNA BINDING PROTEIN; EBNA 2 PROTEIN, HUMAN HERPESVIRUS 4; EBNA-2 PROTEIN, HUMAN HERPESVIRUS 4; ENZYME INHIBITOR; EPSTEIN BARR VIRUS ANTIGEN; ERYTHROID SPECIFIC DNA BINDING FACTOR; FLAVONOID; IMIDAZOLE DERIVATIVE; LIPOPOLYSACCHARIDE; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEA1 PROTEIN, ARABIDOPSIS; PYRIDINE DERIVATIVE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR YY1; VEGETABLE PROTEIN; VIRUS PROTEIN; YY1 PROTEIN, HUMAN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVITY; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INFLAMMATION; MACROPHAGE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; BIOSYNTHESIS; CELL LINE; DRUG ANTAGONISM; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; PLASMID; POLYMERASE CHAIN REACTION; REPORTER GENE; SIGNAL TRANSDUCTION; TIME;

BACTERIA (MICROORGANISMS); HUMAN HERPESVIRUS 4;

ANTIGENS, CD14; ARABIDOPSIS PROTEINS; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPSTEIN-BARR VIRUS NUCLEAR ANTIGENS; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; FLAVONOIDS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; HUMANS; IMIDAZOLES; INTERLEUKIN-10; LIPOPOLYSACCHARIDES; LUCIFERASES; MACROPHAGES; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLANT PROTEINS; PLASMIDS; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PYRIDINES; SIGNAL TRANSDUCTION; SP1 TRANSCRIPTION FACTOR; TIME FACTORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; VIRAL PROTEINS; YY1 TRANSCRIPTION FACTOR;

EID: 0035958007     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M011157200     Document Type: Article

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