메뉴 건너뛰기




Volumn 88, Issue 6, 2010, Pages 1259-1269

Anti-inflammatory properties of the PI3K pathway are mediated by IL-10/DUSP regulation

Author keywords

Inflammation; Macrophage; PTEN

Indexed keywords

DUAL SPECIFICITY PHOSPHATASE; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TOLL LIKE RECEPTOR;

EID: 78649739164     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1189/jlb.0110001     Document Type: Article
Times cited : (53)

References (36)
  • 1
    • 26244446442 scopus 로고    scopus 로고
    • Acute lung injury and the acute respiratory distress syndrome: Four decades of inquiry into pathogenesis and rational management
    • Matthay, M. A., Zimmerman, G. A. (2005) Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management. Am. J. Respir. Cell Mol. Biol. 33, 319-327.
    • (2005) Am. J. Respir. Cell Mol. Biol. , vol.33 , pp. 319-327
    • Matthay, M.A.1    Zimmerman, G.A.2
  • 2
    • 41649103890 scopus 로고    scopus 로고
    • Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins
    • Dalpke, A., Heeg, K., Bartz, H., Baetz, A. (2008) Regulation of innate immunity by suppressor of cytokine signaling (SOCS) proteins. Immunobiology 213, 225-235.
    • (2008) Immunobiology , vol.213 , pp. 225-235
    • Dalpke, A.1    Heeg, K.2    Bartz, H.3    Baetz, A.4
  • 5
    • 52749098868 scopus 로고    scopus 로고
    • Recent advances in the genetic analysis of PTEN and PI3K innate immune properties
    • Günzl, P., Schabbauer, G. (2008) Recent advances in the genetic analysis of PTEN and PI3K innate immune properties. Immunobiology 213, 759-765.
    • (2008) Immunobiology , vol.213 , pp. 759-765
    • Günzl, P.1    Schabbauer, G.2
  • 6
    • 44849113635 scopus 로고    scopus 로고
    • Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages
    • Luyendyk, J. P., Schabbauer, G. A., Tencati, M., Holscher, T., Pawlinski, R., Mackman, N. (2008) Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages. J. Immunol. 180, 4218-4226.
    • (2008) J. Immunol. , vol.180 , pp. 4218-4226
    • Luyendyk, J.P.1    Schabbauer, G.A.2    Tencati, M.3    Holscher, T.4    Pawlinski, R.5    Mackman, N.6
  • 7
    • 41849122634 scopus 로고    scopus 로고
    • TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages
    • Schabbauer, G., Luyendyk, J., Crozat, K., Jiang, Z., Mackman, N., Bahram, S., Georgel, P. (2008) TLR4/CD14-mediated PI3K activation is an essential component of interferon-dependent VSV resistance in macrophages. Mol. Immunol. 45, 2790-2796.
    • (2008) Mol. Immunol. , vol.45 , pp. 2790-2796
    • Schabbauer, G.1    Luyendyk, J.2    Crozat, K.3    Jiang, Z.4    Mackman, N.5    Bahram, S.6    Georgel, P.7
  • 9
    • 56749156696 scopus 로고    scopus 로고
    • The PI3K/Akt/mTOR pathway in innate immune cells: Emerging therapeutic applications
    • Weichhart, T., Saemann, M. D. (2008) The PI3K/Akt/mTOR pathway in innate immune cells: emerging therapeutic applications. Ann. Rheum. Dis. 67 (Suppl. 3), iii70-iii74.
    • (2008) Ann. Rheum. Dis. , vol.67 , Issue.SUPPL. 3
    • Weichhart, T.1    Saemann, M.D.2
  • 11
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley, L. C. (2002) The phosphoinositide 3-kinase pathway. Science 296, 1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 12
    • 0033177995 scopus 로고    scopus 로고
    • Conditional gene targeting in macrophages and granulocytes using LysMcre mice
    • Clausen, B. E., Burkhardt, C., Reith, W., Renkawitz, R., Forster, I. (1999) Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8, 265-277.
    • (1999) Transgenic Res. , vol.8 , pp. 265-277
    • Clausen, B.E.1    Burkhardt, C.2    Reith, W.3    Renkawitz, R.4    Forster, I.5
  • 13
    • 33947698363 scopus 로고    scopus 로고
    • Regulation of innate immunity by MAPK dual-specificity phosphatases: Knockout models reveal new tricks of old genes
    • Salojin, K., Oravecz, T. (2007) Regulation of innate immunity by MAPK dual-specificity phosphatases: knockout models reveal new tricks of old genes. J. Leukoc. Biol. 81, 860-869.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 860-869
    • Salojin, K.1    Oravecz, T.2
  • 15
    • 31144452241 scopus 로고    scopus 로고
    • Essential role of MAPK phosphatase-1 in the negative control of innate immune responses
    • Salojin, K. V., Owusu, I. B., Millerchip, K. A., Potter, M., Platt, K. A., Oravecz, T. (2006) Essential role of MAPK phosphatase-1 in the negative control of innate immune responses. J. Immunol. 176, 1899-1907.
    • (2006) J. Immunol. , vol.176 , pp. 1899-1907
    • Salojin, K.V.1    Owusu, I.B.2    Millerchip, K.A.3    Potter, M.4    Platt, K.A.5    Oravecz, T.6
  • 18
    • 28944448200 scopus 로고    scopus 로고
    • The dual specificity phosphatase transcriptome of the murine thymus
    • Tanzola, M. B., Kersh, G. J. (2006) The dual specificity phosphatase transcriptome of the murine thymus. Mol. Immunol. 43, 754-762.
    • (2006) Mol. Immunol. , vol.43 , pp. 754-762
    • Tanzola, M.B.1    Kersh, G.J.2
  • 20
    • 30944438027 scopus 로고    scopus 로고
    • The acute-phase response and serum amyloid a inhibit the inflammatory response to Acinetobacter baumannii pneumonia
    • Renckens, R., Roelofs, J. J., Knapp, S., de Vos, A. F., Florquin, S., van der Poll, T. (2006) The acute-phase response and serum amyloid A inhibit the inflammatory response to Acinetobacter baumannii pneumonia. J. Infect. Dis. 193, 187-195.
    • (2006) J. Infect. Dis. , vol.193 , pp. 187-195
    • Renckens, R.1    Roelofs, J.J.2    Knapp, S.3    De Vos, A.F.4    Florquin, S.5    Van Der Poll, T.6
  • 21
    • 1342324587 scopus 로고    scopus 로고
    • Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense
    • Knapp, S., Wieland, C. W., van't Veer, C., Takeuchi, O., Akira, S., Florquin, S., van der Poll, T. (2004) Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense. J. Immunol. 172, 3132-3138.
    • (2004) J. Immunol. , vol.172 , pp. 3132-3138
    • Knapp, S.1    Wieland, C.W.2    Van't Veer, C.3    Takeuchi, O.4    Akira, S.5    Florquin, S.6    Van Der Poll, T.7
  • 23
    • 0035104119 scopus 로고    scopus 로고
    • LPS induction of gene expression in human monocytes
    • Guha, M., Mackman, N. (2001) LPS induction of gene expression in human monocytes. Cell. Signal. 13, 85-94.
    • (2001) Cell. Signal. , vol.13 , pp. 85-94
    • Guha, M.1    Mackman, N.2
  • 24
    • 0035469890 scopus 로고    scopus 로고
    • Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation and Egr-1 expression
    • Guha, M., O'Connell, M. A., Pawlinski, R., Hollis, A., McGovern, P., Yan, S. F., Stern, D., Mackman, N. (2001) Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation and Egr-1 expression. Blood 98, 1429-1439.
    • (2001) Blood , vol.98 , pp. 1429-1439
    • Guha, M.1    O'Connell, M.A.2    Pawlinski, R.3    Hollis, A.4    McGovern, P.5    Yan, S.F.6    Stern, D.7    Mackman, N.8
  • 25
    • 0030858764 scopus 로고    scopus 로고
    • Lipopolysaccharide induction of the tumor necrosis factor-α promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-κB transcription factors
    • Yao, J., Mackman, N., Edgington, T. S., Fan, S. T. (1997) Lipopolysaccharide induction of the tumor necrosis factor-α promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and NF-κB transcription factors. J. Biol. Chem. 272, 17795-17801.
    • (1997) J. Biol. Chem. , vol.272 , pp. 17795-17801
    • Yao, J.1    Mackman, N.2    Edgington, T.S.3    Fan, S.T.4
  • 26
    • 33144460185 scopus 로고    scopus 로고
    • Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses
    • Chi, H., Barry, S. P., Roth, R. J., Wu, J. J., Jones, E. A., Bennett, A. M., Flavell, R. A. (2006) Dynamic regulation of pro- and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses. Proc. Natl. Acad. Sci. USA 103, 2274-2279.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 2274-2279
    • Chi, H.1    Barry, S.P.2    Roth, R.J.3    Wu, J.J.4    Jones, E.A.5    Bennett, A.M.6    Flavell, R.A.7
  • 27
    • 31344475056 scopus 로고    scopus 로고
    • Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock
    • Hammer, M., Mages, J., Dietrich, H., Servatius, A., Howells, N., Cato, A. C., Lang, R. (2006) Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock. J. Exp. Med. 203, 15-20.
    • (2006) J. Exp. Med. , vol.203 , pp. 15-20
    • Hammer, M.1    Mages, J.2    Dietrich, H.3    Servatius, A.4    Howells, N.5    Cato, A.C.6    Lang, R.7
  • 28
    • 33751566645 scopus 로고    scopus 로고
    • DUSP meet immunology: Dual specificity MAPK phosphatases in control of the inflammatory response
    • Lang, R., Hammer, M., Mages, J. (2006) DUSP meet immunology: dual specificity MAPK phosphatases in control of the inflammatory response. J. Immunol. 177, 7497-7504. (Pubitemid 44846262)
    • (2006) Journal of Immunology , vol.177 , Issue.11 , pp. 7497-7504
    • Lang, R.1    Hammer, M.2    Mages, J.3
  • 29
    • 0038832564 scopus 로고    scopus 로고
    • Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation
    • Brondello, J. M., Pouyssegur, J., McKenzie, F. R. (1999) Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation. Science 286, 2514-2517.
    • (1999) Science , vol.286 , pp. 2514-2517
    • Brondello, J.M.1    Pouyssegur, J.2    McKenzie, F.R.3
  • 32
    • 23944486750 scopus 로고    scopus 로고
    • Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3
    • Martin, M., Rehani, K., Jope, R. S., Michalek, S. M. (2005) Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. Nat. Immunol. 6, 777-784.
    • (2005) Nat. Immunol. , vol.6 , pp. 777-784
    • Martin, M.1    Rehani, K.2    Jope, R.S.3    Michalek, S.M.4
  • 34
    • 0030794511 scopus 로고    scopus 로고
    • Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells
    • Franklin, C. C., Kraft, A. S. (1997) Conditional expression of the mitogen-activated protein kinase (MAPK) phosphatase MKP-1 preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells. J. Biol. Chem. 272, 16917-16923.
    • (1997) J. Biol. Chem. , vol.272 , pp. 16917-16923
    • Franklin, C.C.1    Kraft, A.S.2
  • 35
    • 41549107522 scopus 로고    scopus 로고
    • Cytokine signaling modules in inflammatory responses
    • O'Shea, J. J., Murray, P. J. (2008) Cytokine signaling modules in inflammatory responses. Immunity 28, 477-487.
    • (2008) Immunity , vol.28 , pp. 477-487
    • O'Shea, J.J.1    Murray, P.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.