Myocyte-derived Hsp90 modulates collagen upregulation via biphasic activation of STAT-3 in fibroblasts during cardiac hypertrophy

Molecular and Cellular Biology

Volumn 37, Issue 6, 2017, Pages

  Datta, Ritwik ^a   Bansal, Trisha ^a   Rana, Santanu ^a   Datta, Kaberi ^a   Datta Chaudhuri, Ratul ^a   Chawla Sarkar, Mamta ^b   Sarkar, Sagartirtha ^a  

^a UNIVERSITY OF CALCUTTA   (India)

^b NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES   (India)

Author keywords

Cardiac hypertrophy; Collagen; Hsp90; Myocyte fibroblast cross talk; STAT 3

Indexed keywords

CELASTROL; CELL CYCLE PROTEIN 37; COLLAGEN; HEAT SHOCK PROTEIN 90; I KAPPA B KINASE BETA; INTERLEUKIN 6; STAT3 PROTEIN; TANESPIMYCIN; UBIQUITIN; BENZOQUINONE DERIVATIVE; I KAPPA B KINASE; MACROCYCLIC LACTAM; PROTEASOME; PROTEASOME INHIBITOR; TRANSCRIPTION FACTOR RELA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; COLLAGEN SYNTHESIS; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXOSOME; HEART FIBROBLAST; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; KIDNEY ARTERY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; CARDIOMEGALY; CELL MOTION; DOWN REGULATION; DRUG EFFECTS; FIBROBLAST; METABOLISM; PATHOLOGY; PHOSPHORYLATION; PROTEIN STABILITY; SECRETION (PROCESS); WISTAR RAT;

ANIMALS; BENZOQUINONES; CARDIOMEGALY; CELL MOVEMENT; COLLAGEN; DOWN-REGULATION; EXOSOMES; FIBROBLASTS; HSP90 HEAT-SHOCK PROTEINS; I-KAPPA B KINASE; INTERLEUKIN-6; LACTAMS, MACROCYCLIC; MALE; MODELS, BIOLOGICAL; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; PROTEIN STABILITY; RATS, WISTAR; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA; UBIQUITIN; UP-REGULATION;

EID: 85014335347     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.00611-16     Document Type: Article

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