Blockade of exosome generation with GW4869 dampens the sepsis-induced inflammation and cardiac dysfunction

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 11, 2015, Pages 2362-2371

  Essandoh, Kobina ^a   Yang, Liwang ^a,e   Wang, Xiaohong ^a   Huang, Wei ^a   Qin, Dongze ^a,f   Hao, Jiukuan ^b   Wang, Yigang ^a   Zingarelli, Basilia ^c   Peng, Tianqing ^d   Fan, Guo Chang ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF CINCINNATI   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d LAWSON HEALTH RESEARCH INSTITUTE   (Canada)

^e SHANXI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^f SHANXI MEDICAL UNIVERSITY   (China)

Author keywords

Cardiac dysfunction; Exosomes; Inflammatory response; Macrophages; Sepsis

Indexed keywords

3,3' (1,4 PHENYLENE)BIS[N [4 (4,5 DIHYDRO 1H IMIDAZOL 2 YL)PHENYL]ACRYLAMIDE]; ENDOTOXIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; EXOSOME; HEART DISEASE; HEART FUNCTION; INFLAMMATION; MACROPHAGE; MALE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPSIS;

EID: 84940766267     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2015.08.010     Document Type: Article

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