A spatio-temporal cardiomyocyte targeted vector system for efficient delivery of therapeutic payloads to regress cardiac hypertrophy abating bystander effect

Journal of Controlled Release

Volumn 200, Issue , 2015, Pages 167-178

  Rana, Santanu ^a   Datta, Kaberi ^a   Reddy, Teegala Lakshminarayan ^b   Chatterjee, Emeli ^a   Sen, Preeta ^a   Pal Bhadra, Manika ^b   Bhadra, Utpal ^c   Pramanik, Arindam ^d   Pramanik, Panchanan ^d   Chawla Sarkar, Mamta ^e   Sarkar, Sagartirtha ^a  

^a UNIVERSITY OF CALCUTTA   (India)

^b INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^c CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^d INDIAN INSTITUTE OF TECHNOLOGY   (India)

^e NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES   (India)

Author keywords

Carboxy methyl chitosan; Cardiac tissue engineering; Cardiomyocyte; Drug delivery; Gene therapy

Indexed keywords

CHITIN; CHITOSAN; DRUG DELIVERY; DRUG THERAPY; ENZYME INHIBITION; GENE THERAPY; GENES; MOLECULES; PATHOLOGY; PEPTIDES; TISSUE; TISSUE ENGINEERING;

BETA ADRENERGIC RECEPTOR; BIOACTIVE MOLECULES; CARBOXYMETHYL CHITOSAN; CARDIAC HYPERTROPHY; CARDIAC TISSUE ENGINEERING; CARDIOMYOCYTES; CARDIOVASCULAR DYSFUNCTION; THERAPEUTIC STRATEGY;

HEART;

ATRIAL NATRIURETIC FACTOR; CARVEDILOL; CHITOSAN DERIVATIVE; COLLAGEN TYPE 3; MYOSIN HEAVY CHAIN BETA; NANOPARTICLE; POLYMER; PROTEIN P53; SMALL INTERFERING RNA; STEARIC ACID; CARBAZOLE DERIVATIVE; CARDIOTONIC AGENT; CHITOSAN; PEPTIDE; PROPANOLAMINE DERIVATIVE; STEARIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; BYSTANDER EFFECT; CELL LOSS; CONJUGATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ENCAPSULATION; ENDOCYTOSIS; FLUORESCENCE ANALYSIS; GENE EXPRESSION; HEART MUSCLE; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HYDRODYNAMICS; IN VITRO STUDY; INTERNALIZATION; M MODE ECHOCARDIOGRAPHY; MOLECULAR WEIGHT; MTS ASSAY; NONHUMAN; PH; PRIORITY JOURNAL; RAT; TISSUE ENGINEERING; ANALOGS AND DERIVATIVES; ANIMAL; CARDIOMEGALY; CELL CULTURE; CHEMISTRY; GENE TRANSFER; GENETICS; HUMAN; WISTAR RAT;

ANIMALS; BYSTANDER EFFECT; CARBAZOLES; CARDIOMEGALY; CARDIOTONIC AGENTS; CELLS, CULTURED; CHITOSAN; DRUG DELIVERY SYSTEMS; GENE TRANSFER TECHNIQUES; HUMANS; MYOCYTES, CARDIAC; NANOPARTICLES; PEPTIDES; PROPANOLAMINES; RATS, WISTAR; RNA, SMALL INTERFERING; STEARIC ACIDS; TISSUE ENGINEERING; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84921058769     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.01.008     Document Type: Article

References (34)

1. N. Frey, and E.N. Olson Cardiac hypertrophy: the good, the bad, and the ugly Annu. Rev. Physiol. 65 2003 45 79
2. E. Song, S.K. Lee, J. Wang, N. Ince, N. Ouyang, J. Min, J. Chen, P. Shankar, and J. Lieberman RNA interference targeting Fas protects mice from fulminant hepatitis Nat. Med. 9 2003 347 351
3. W. Arap, R. Pasqualini, and E. Ruoslahti Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model Science 279 1998 377 380
4. A.J. Ditto, P.N. Shah, and Y.H. Yun Non-viral gene delivery using nanoparticles Expert Opin. Drug Deliv. 6 2009 1149 1160
5. K. Strebhardt, and A. Ullrich Paul Ehrlich's magic bullet concept: 100 years of progress Nat. Rev. Cancer 8 2008 473 480
6. R. Pasqualini, and E. Ruoslahti Organ targeting in vivo using phage display peptide libraries Nature 380 1996 364 366
7. M.J. McGuire, K.N. Samli, S.A. Johnston, and K.C. Brown In vitro selection of a peptide with high affinity for cardiomyocytes in vivo J. Mol. Biol. 342 2004 171 182
8. Y. Shigemasa, and S. Minami Application of chitin and chitosan for biomaterials Biotechnol. Genet. Eng. Rev. 13 1996 383 420
9. G. Borchard Chitosans for gene delivery Adv. Drug Deliv. Rev. 52 2001 145 150
10. S. Sanyakamdhorn, D. Agudelo, and H.A. Tajmir-Riahi Encapsulation of antitumor drug doxorubicin and its analogue by chitosan nanoparticles Biomacromolecules 14 2013 557 563
11. H.Q. Mao, K. Roy, V.L. Troung-Le, K.A. Janes, K.Y. Lin, Y. Wang, J.T. August, and K.W. Leong Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency J. Control. Release 70 2001 399 421
12. M. Thanou, J.C. Verhoef, and H.E. Junginger Chitosan and its derivatives as intestinal absorption enhancers Adv. Drug Deliv. Rev. 50 Suppl. 1 2001 S91 S101
13. C. Chen-Scarabelli, L. Jr Saravolatz, Y. Murad, W.S. Shieh, W. Qureshi, J. Di Rezze, R. Abrencillo, T. Gardin, U.K. Gidwani, L. Saravolatz, G. Faggian, and T.M. Scarabelli A critical review of the use of Carvedilol in ischemic heart disease Am. J. Cardiovasc. Drugs 12 2012 391 401
14. B. Kveiborg, B. Christiansen, A. Major-Petersen, and C. Torp-Pedersen Metabolic effects of beta-adrenoceptor antagonists with special emphasis on Carvedilol Am. J. Cardiovasc. Drugs 6 2006 209 217
15. V.A. Fonseca Effects of beta-blockers on glucose and lipid metabolism Curr. Med. Res. Opin. 26 2010 615 629
16. B. Das, D. Young, A. Vasanji, S. Gupta, S. Sarkar, and S. Sen Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure Cardiovasc. Res. 87 2010 524 534
17. T. Soussi, and K.G. Wiman Shaping genetic alterations in human cancer: the p53 mutation paradigm Cancer Cell 12 2007 303 312
18. S.K. Sahu, S. Maiti, T.K. Maiti, S.K. Ghosh, and P. Pramanik Hydrophobically modified carboxymethyl chitosan nanoparticles targeted delivery of paclitaxel J. Drug Target. 19 2011 104 113
19. T.S. Kashi, S. Eskandarion, M. Esfandyari-Manesh, S.M. Marashi, N. Samadi, S.M. Fatemi, F. Atyabi, S. Eshraghi, and R. Dinarvand Improved drug loading and antibacterial activity of minocycline-loaded PLGA nanoparticles prepared by solid/oil/water ion pairing method Int. J. Nanomedicine 7 2012 221 234
20. G. Zhang, B. Guo, H. Wu, T. Tang, B.T. Zhang, L. Zheng, Y. He, Z. Yang, X. Pan, H. Chow, K. To, Y. Li, D. Li, X. Wang, Y. Wang, K. Lee, Z. Hou, N. Dong, G. Li, K. Leung, L. Hung, F. He, L. Zhang, and L. Qin A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy Nat. Med. 18 2012 307 314
21. A. Chatterjee, S.A. Mir, D. Dutta, A. Mitra, K. Pathak, and S. Sarkar Analysis of p53 and NF-κB signaling in modulating the cardiomyocyte fate during hypertrophy J. Cell. Physiol. 226 2011 2543 2554
22. S. Sarkar, D.W. Leaman, S. Gupta, P. Sil, D. Young, A. Morehead, D. Mukherjee, N. Ratliff, Y. Sun, M. Rayborn, J. Hollyfield, and S. Sen Cardiac overexpression of myotrophin triggers myocardial hypertrophy and heart failure in transgenic mice J. Biol. Chem. 279 2004 20422 20434
23. M. Campbell, A.T. Nguyen, A.S. Kiang, L.C. Tam, O.L. Gobbo, C. Kerskens, S. Ni Dhubhghaill, M.M. Humphries, G.J. Farrar, P.F. Kenna, and P. Humphries An experimental platform for systemic drug delivery to the retina Proc. Natl. Acad. Sci. U.S.A. 106 2009 17817 17822
24. S.A. Mir, A. Chatterjee, A. Mitra, K. Pathak, S.K. Mahata, and S. Sarkar Inhibition of signal transducer and activator of transcription 3 (STAT3) attenuates interleukin-6 (IL-6)-induced collagen synthesis and resultant hypertrophy in rat heart J. Biol. Chem. 287 2012 2666 2677
25. S. Sen, R.C. Tarazi, P.A. Khairallah, and F.M. Bumpus Cardiac hypertrophy in spontaneously hypertensive rats Circ. Res. 35 1974 775 781
26. A. Mitra, T. Basak, K. Datta, S. Naskar, S. Sengupta, and S. Sarkar Role of α-crystallin B as a regulatory switch in modulating cardiomyocyte apoptosis by mitochondria or endoplasmic reticulum during cardiac hypertrophy and myocardial infarction Cell Death Dis. 4 2013 e582
27. A. Mitra, A. Ray, R. Datta, S. Sengupta, and S. Sarkar Cardioprotective role of P38 MAPK during myocardial infarction via parallel activation of α-crystallin B and Nrf2 J. Cell. Physiol. 229 2014 1272 1282
28. K.N. Sugahara, T. Teesalu, P.P. Karmali, V.R. Kotamraju, L. Agemy, O.M. Girard, D. Hanahan, R.F. Mattrey, and E. Ruoslahti Tissue-penetrating delivery of compounds and nanoparticles into tumors Cancer Cell 16 2009 510 520
29. C.L. Watkins, P. Brennan, C. Fegan, K. Takayama, I. Nakase, S. Futaki, and A.T. Jones Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD J. Control. Release 140 2009 237 244
30. S. Sarkar, M. Chawla-Sarkar, D. Young, K. Nishiyama, M.E. Rayborn, J.G. Hollyfield, and S. Sen Myocardial cell death and regeneration during progression of cardiac hypertrophy to heart failure J. Biol. Chem. 279 2004 52630 52642
31. A.K. Varkouhi, M. Scholte, G. Storm, and H.J. Haisma Endosomal escape pathways for delivery of biologicals J. Control. Release 151 2011 220 228
32. J. Lee, K.S. Yun, C.S. Choi, S.H. Shin, H.S. Ban, T. Rhim, S.K. Lee, and K.Y. Lee Cell-specific siRNA delivery using antibody-conjugated chitosan nanoparticles Bioconjug. Chem. 23 2012 1174 1180
33. S.Y. Lee, M.S. Huh, S. Lee, S.J. Lee, H. Chung, J.H. Park, Y.K. Oh, K. Choi, K. Kim, and I.C. Kwon Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing J. Control. Release 141 2010 339 346
34. R. Wang, T. Miura, N. Harada, R. Kametani, M. Shibuya, Y. Fukagawa, S. Kawamura, Y. Ikeda, M. Hara, and M. Matsuzaki Pleiotropic effects of the beta-adrenoceptor blocker Carvedilol on calcium regulation during oxidative stress-induced apoptosis in cardiomyocytes J. Pharmacol. Exp. Ther. 318 2006 45 52