Analysis of p53 and NF-κB signaling in modulating the cardiomyocyte fate during hypertrophy

Journal of Cellular Physiology

Volumn 226, Issue 10, 2011, Pages 2543-2554

  Chatterjee, Arunachal ^a   Mir, Saiful A ^a   Dutta, Dipanjan ^b   Mitra, Arkadeep ^a   Pathak, Kanchan ^a   Sarkar, Sagartirtha ^a  

^a UNIVERSITY OF CALCUTTA   (India)

^b NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; BIOLOGICAL MARKER; CASPASE 3; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; FAS ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KI 67 ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P300; PROTEIN P53; SMALL INTERFERING RNA; SYNAPTOTAGMIN I;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; HEART HYPERTROPHY; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; INHIBITION KINETICS; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AGE FACTORS; ANGIOTENSIN II; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CARDIOMEGALY; CELLS, CULTURED; MALE; MYOCYTES, CARDIAC; NF-KAPPA B; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; VASOCONSTRICTOR AGENTS;

RATTUS; RATTUS NORVEGICUS;

EID: 79960675340     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.22599     Document Type: Article

References (42)

1. Avantaggiati ML, Ogryzko V, Gardner K, Giordano A, Levine AS, Kelly K. 1997. Recruitment of p300/CBP in p53-dependent signal pathways. Cell 89: 1175-1184.
2. Beate F, Lohmann SM, Smolenski A, Linnemüller S, Pieske B, Schröder F, Molkentin JD, Drexler H, Wollert KC. 2002. Inhibition of calcineurin-NFAT hypertrophy signaling by cGMP-dependent protein kinase type I in cardiac myocytes. Proc Natl Acad Sci 99: 11363-11368.
3. Beltrami AP, Urbanek K, Kajstura J, Yan SM, Finato N, Bussani R, Nadal-Ginard B, Silvestri F, Leri A, Beltrami CA, Anversa P. 2001. Evidence that human cardiac myocytes divide after myocardial infarction. N Engl J Med 344: 1750-1757.
4. Black SC, Huang JQ, Rezaiefar P, Radinovic S, Eberhart A, Nicholson DW, Rodger IW. 1998. Co-localization of the cysteine protease caspase-3 with apoptotic myocytes after in vivo myocardial ischemia and reperfusion in the rat. J Mol Cell Cardiol 30: 733-742.
5. Brady HJ, Gil-Gomez G, Kirberg J, Berns AJ. 1996. Bax alpha perturbs T cell development and affects cell cycle entry of T cells. EMBO J 15: 6991-7001.
6. Campbell KJ, Chapman NR, Perkins ND. 2001. UV stimulation induces nuclear factor kappaB (NF-kappaB) DNA-binding activity but not transcriptional activation. Biochem Soc Trans 29: 688-691.
7. Chen L, Fischle W, Verdin E, Greene WC. 2001. Duration of nuclear NF-κB action regulated by reversible acetylation. Science 293: 1653-1657.
8. Chen LF, Mu Y, Greene WC. 2002. Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-κB. EMBO J 21: 6539-6548.
9. Das A, Smolenski A, Lohmann SM, Kukreja RC. 2006. Cyclic GMP-dependent protein kinaseIα attenuates necrosis and apoptosis following ischemia/reoxygenation in adult cardiomyocyte. J Biol Chem 281: 38644-38652.
10. Das B, Young D, Vasanji A, Gupta S, Sarkar S, Sen S. 2010. Influence of p53 in the transition of myotrophin-induced cardiac hypertrophy to heart failure. Cardiovasc Res 87: 524-534.
11. Dignam JD, Martin PL, Shastry BS, Roeder RG. 1983. Eukaryotic gene transcription with purified components. Methods Enzymol 101: 582-598.
12. Elewaut D, DiDonatoJ A, Kim JM, Truong F, Eckmann L, Kagnoff MF. 1999. NF-kappa B is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria. J Immunol 163: 1457-1466.
13. Evan GI, Wyllie AH, Gilbert CS, Littlewood TD, Land H, Brooks M, Waters CM, Penn LZ, Hancock DC. 1992. Induction of apoptosis in fibroblast by c-myc protein. Cell 69: 119-128.
14. Fernández-Majada V, Aguilera C, Villanueva A, Vilardell F, Robert-Moreno A, Aytés A, Real FX, Capella G, Mayo MW, Espinosa L, Bigas A. 2007. Nuclear IKK activity leads to dysregulated Notch-dependent gene expression in colorectal cancer. Proc Natl Acad Sci 104: 276-281.
15. Gupta S, Purcell NH, Lin A, Sen S. 2002. Activation of nuclear factor-κB is necessary for myotrophin-induced cardiac hypertrophy. J Cell Biol 159: 1019-1028.
16. Gupta S, Young D, Sen S. 2005. Inhibition of NF-κB induces regression of cardiac hypertrophy, independent of blood pressure control, in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 289: H20-H29.
17. Haupt S, Berger M, Goldberg Z, Haupt Y. 2003. Apoptosis-The p53 network. J Cell Sci 116: 4077-4085.
18. Hou Q, Hsu Y. 2005. Bax translocates from cytosol to mitochondria in cardiac cells during apoptosis: Development of a GFP-Bax-stable H9c2 cell line for apoptosis analysis. Am J Physiol Heart Circ Physiol 289: H477-H487.
19. Jopling C, Sleep E, Raya M, Marti{dotless}́ M, Raya A, Belmonte JCI. 2010. Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation. Nature 464: 606-609.
20. Komarov PG, Komarova EA, Kondratov RV, Christov-Tselkov K, Coon JS, Chernov MV, Gudkov AV. 1999. A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy. Science 285: 1733-1737.
21. Lee P, Sata M, Lefer DJ, Factor SM, Walsh K, Kitsis RN. 2003. Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo. Am J Physiol Heart Circ Physiol 284: H456-H463.
22. Lill NL, Grossman SR, Ginsberg D, DeCaprio J, Livingston DM. 1997. Binding and modulation of p53 by p300/CBP coactivators. Nature 387: 823-827.
23. Mazel S, Burtrum D, Petrie HT. 1996. Regulation of cell division cycle progression by bcl-2 expression: A potential mechanism for inhibition of programmed cell death. J Exp Med 183: 2219-2226.
24. Meikrantz W, Schlegel R. 1995. Apoptosis and the cell cycle. J Cell Biochem 58: 160-174.
25. Morgan DO. 1995. Principles of CDK regulation. Nature 374: 131-134.
26. Nakagawa Y, Kuwahara K, Takemura G, Akao M, Kato M, Arai Y, Takano M, Harada M, Murakami M, Nakanishi M, Usami S, Yasuno S, Kinoshita H, Fujiwara M, Ueshima K, Nakao K. 2009. p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts. Circ Res 105: 746-754.
27. Norbury C, Nurse P. 1992. Animal cell cycles and their control. Annu Rev Biochem 61: 441-470.
28. Olivetti G, Abbi R, Quaini F, Kajstura J, Cheng W, Nitahara JA, Quaini E, Di Loreto C, Beltrami CA, Krajewski S, Reed JC, Anversa P. 1997. Apoptosis in the failing human heart. N Engl J Med 336: 1131-1141.
29. Pathak M, Sarkar S, Vellaichamy E, Sen S. 2001. Role of myocytes in myocardial collagen production. Hypertension 37: 833-840.
30. Rojo-Ortega JM, Genest J. 1968. A method for production of experimental hypertension in rats. Can J Physiol Pharmacol 46: 883-885.
31. Sano M, Minamino T, Toko H, Miyauchi H, Orimo M, Qin Y, Akazawa H, Tateno K, Kayama Y, Harada M, Shimizu I, Asahara T, Hamada H, Tomita S, Molkentin JD, Zou Y, Komuro I. 2007. p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overload. Nature 446: 444-448.
32. Sarkar S, Leaman DW, Gupta S, Sil P, Young D, Morehead A, Mukherjee D, Ratliff N, Sun Y, Rayborn M, Hollyfield J, Sen S. 2004. Cardiac overexpression of myotrophin triggers myocardial hypertrophy and heart failure in transgenic mice. J Biol Chem 279: 20422-20434.
33. Sarkar S, Sarkar MC, Young D, Nishiyama K, Rayborn ME, Hollyfield JG, Sen S. 2004a. Myocardial cell death and regeneration during progression of cardiac hypertrophy to heart failure. J Biol Chem 279: 52630-52642.
34. Schaub MC, Hefti MA, Zaugg M. 2006. Integration of calcium with the signaling network in cardiac myocytes. J Mol Cell Cardiol 41: 183-214.
35. Sen S, Tarazi RC, Khairallah PA, Bumpus FM. 1974. Cardiac hypertrophy in spontaneously hypertensive rats. Circ Res 35: 775-781.
36. Sil P, Sen S. 1997. Angiotensin II and myocyte growth: Role of fibroblasts. Hypertension 30: 209-216.
37. Wang D, Baldwin AS Jr. 1998. Activation of nuclear factor-κB-dependent transcription by tumor necrosis factor-α is mediated through phosphorylation of RelA/p65 on serine 529. J Biol Chem 273: 29411-29416.
38. Wang CY, Mayo MW, Korneluk RG, Goeddel DV, Baldwin AS Jr. 1998. NF-kappaB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281: 1680-1683.
39. Webster GA, Perkins ND. 1999. Transcriptional cross talk between NF-κB and p53. Mol Cell Biol 19: 3485-3495.
40. Zelarayan L, Renger A, Noack C, Zafiriou MP, Gehrke C, Nagel R, Dietz R, Windt L, Bergmann MW. 2009. NF-κB activation is required for adaptive cardiac hypertrophy. Cardiovasc Res 84: 416-424.
41. Zhong H, SuYang H, Erdjument-Bromage H, Tempst P, Ghosh S. 1997. The transcriptional activity of NF-κB is regulated by the IκB-associated PKAc subunit through a cyclic AMP-independent mechanism. Cell 89: 413-424.
42. Zorc M, Vraspir-Porenta O, Zorc-Pleskovic R, Radovanovic N, Petrovic D. 2003. Apoptosis of myocytes and proliferation markers as prognostic factors in end-stage dilated cardiomyopathy. Cardiovasc Pathol 12: 36-39.