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Volumn 83, Issue , 2017, Pages 721-735

The habenula in psychiatric disorders: More than three decades of translational investigation

Author keywords

Bipolar disorder; Depression; Habenula; Reward; Schizophrenia; Substance use disorder

Indexed keywords

COCAINE; DOPAMINE; DOPAMINE 2 RECEPTOR; MORPHINE; SEROTONIN;

EID: 85014089198     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2017.02.010     Document Type: Review
Times cited : (72)

References (204)
  • 1
    • 84902598427 scopus 로고    scopus 로고
    • Hyperactivation of the habenula as a link between depression and sleep disturbance
    • Aizawa, H., Cui, W., Tanaka, K., Okamoto, H., Hyperactivation of the habenula as a link between depression and sleep disturbance. Front. Hum. Neurosci., 7, 2013, 826.
    • (2013) Front. Hum. Neurosci. , vol.7 , pp. 826
    • Aizawa, H.1    Cui, W.2    Tanaka, K.3    Okamoto, H.4
  • 2
    • 0035955499 scopus 로고    scopus 로고
    • The role of the habenular complex in the elevation of dorsal raphe nucleus serotonin and the changes in the behavioral responses produced by uncontrollable stress
    • Amat, J., Sparks, P.D., Matus-Amat, P., Griggs, J., Watkins, L.R., Maier, S.F., The role of the habenular complex in the elevation of dorsal raphe nucleus serotonin and the changes in the behavioral responses produced by uncontrollable stress. Brain Res. 917 (2001), 118–126.
    • (2001) Brain Res. , vol.917 , pp. 118-126
    • Amat, J.1    Sparks, P.D.2    Matus-Amat, P.3    Griggs, J.4    Watkins, L.R.5    Maier, S.F.6
  • 3
    • 0345561552 scopus 로고    scopus 로고
    • Subnuclear organization of the rat habenular complexes
    • Andres, K.H., von During, M., Veh, R.W., Subnuclear organization of the rat habenular complexes. J. Comp. Neurol. 407 (1999), 130–150.
    • (1999) J. Comp. Neurol. , vol.407 , pp. 130-150
    • Andres, K.H.1    von During, M.2    Veh, R.W.3
  • 5
    • 84901792980 scopus 로고    scopus 로고
    • Effort, anhedonia, and function in schizophrenia: reduced effort allocation predicts amotivation and functional impairment
    • Barch, D.M., Treadway, M.T., Schoen, N., Effort, anhedonia, and function in schizophrenia: reduced effort allocation predicts amotivation and functional impairment. J. Abnorm. Psychol. 123 (2014), 387–397.
    • (2014) J. Abnorm. Psychol. , vol.123 , pp. 387-397
    • Barch, D.M.1    Treadway, M.T.2    Schoen, N.3
  • 6
    • 0034962758 scopus 로고    scopus 로고
    • Schizophrenia and attention deficit disorder. Two complex disorders of attention
    • Barr, W.B., Schizophrenia and attention deficit disorder. Two complex disorders of attention. Ann. N. Y. Acad. Sci. 931 (2001), 239–250.
    • (2001) Ann. N. Y. Acad. Sci. , vol.931 , pp. 239-250
    • Barr, W.B.1
  • 7
    • 84867260607 scopus 로고    scopus 로고
    • Braking dopamine systems: a new GABA master structure for mesolimbic and nigrostriatal functions
    • Barrot, M., Sesack, S.R., Georges, F., Pistis, M., Hong, S., Jhou, T.C., Braking dopamine systems: a new GABA master structure for mesolimbic and nigrostriatal functions. J. Neurosci. 32 (2012), 14094–14101.
    • (2012) J. Neurosci. , vol.32 , pp. 14094-14101
    • Barrot, M.1    Sesack, S.R.2    Georges, F.3    Pistis, M.4    Hong, S.5    Jhou, T.C.6
  • 8
    • 84939942074 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors control acetylcholine and noradrenaline release in the rodent habenulo-interpeduncular complex
    • Beiranvand, F., Zlabinger, C., Orr-Urtreger, A., Ristl, R., Huck, S., Scholze, P., Nicotinic acetylcholine receptors control acetylcholine and noradrenaline release in the rodent habenulo-interpeduncular complex. Br. J. Pharmacol. 171 (2014), 5209–5224.
    • (2014) Br. J. Pharmacol. , vol.171 , pp. 5209-5224
    • Beiranvand, F.1    Zlabinger, C.2    Orr-Urtreger, A.3    Ristl, R.4    Huck, S.5    Scholze, P.6
  • 9
    • 84959286107 scopus 로고    scopus 로고
    • Morphometric analysis of the cerebral expression of ATP-binding cassette transporter protein ABCB1 in chronic schizophrenia: circumscribed deficits in the habenula
    • Bernstein, H.G., Hildebrandt, J., Dobrowolny, H., Steiner, J., Bogerts, B., Pahnke, J., Morphometric analysis of the cerebral expression of ATP-binding cassette transporter protein ABCB1 in chronic schizophrenia: circumscribed deficits in the habenula. Schizophr. Res., 2016.
    • (2016) Schizophr. Res.
    • Bernstein, H.G.1    Hildebrandt, J.2    Dobrowolny, H.3    Steiner, J.4    Bogerts, B.5    Pahnke, J.6
  • 10
    • 65649141611 scopus 로고    scopus 로고
    • The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain
    • Bianco, I.H., Wilson, S.W., The habenular nuclei: a conserved asymmetric relay station in the vertebrate brain. Philos. Trans. R Soc. Lond. B Biol. Sci. 364 (2009), 1005–1020.
    • (2009) Philos. Trans. R Soc. Lond. B Biol. Sci. , vol.364 , pp. 1005-1020
    • Bianco, I.H.1    Wilson, S.W.2
  • 11
    • 51349156208 scopus 로고    scopus 로고
    • Variants in nicotinic receptors and risk for nicotine dependence
    • Bierut, L.J., et al. Variants in nicotinic receptors and risk for nicotine dependence. Am. J. Psychiatry 165 (2008), 1163–1171.
    • (2008) Am. J. Psychiatry , vol.165 , pp. 1163-1171
    • Bierut, L.J.1
  • 12
    • 33847315633 scopus 로고    scopus 로고
    • Cognitive deficits and functional outcome in schizophrenia
    • Bowie, C.R., Harvey, P.D., Cognitive deficits and functional outcome in schizophrenia. Neuropsychiatr. Dis. Treat. 2 (2006), 531–536.
    • (2006) Neuropsychiatr. Dis. Treat. , vol.2 , pp. 531-536
    • Bowie, C.R.1    Harvey, P.D.2
  • 13
    • 77952876978 scopus 로고    scopus 로고
    • Glutamatergic axons from the lateral habenula mainly terminate on GABAergic neurons of the ventral midbrain
    • Brinschwitz, K., Dittgen, A., Madai, V.I., Lommel, R., Geisler, S., Veh, R.W., Glutamatergic axons from the lateral habenula mainly terminate on GABAergic neurons of the ventral midbrain. Neuroscience 168 (2010), 463–476.
    • (2010) Neuroscience , vol.168 , pp. 463-476
    • Brinschwitz, K.1    Dittgen, A.2    Madai, V.I.3    Lommel, R.4    Geisler, S.5    Veh, R.W.6
  • 14
    • 80052211211 scopus 로고    scopus 로고
    • Lateral habenula neurons signal errors in the prediction of reward information
    • Bromberg-Martin, E.S., Hikosaka, O., Lateral habenula neurons signal errors in the prediction of reward information. Nat. Neurosci. 14 (2011), 1209–1216.
    • (2011) Nat. Neurosci. , vol.14 , pp. 1209-1216
    • Bromberg-Martin, E.S.1    Hikosaka, O.2
  • 15
    • 84986216627 scopus 로고    scopus 로고
    • Functional evidence for a direct excitatory projection from the lateral habenula to the ventral tegmental area in the rat
    • Brown, P.L., Shepard, P.D., Functional evidence for a direct excitatory projection from the lateral habenula to the ventral tegmental area in the rat. J. Neurophysiol.:jn, 00305, 2016, 02016.
    • (2016) J. Neurophysiol.:jn , vol.305 , pp. 02016
    • Brown, P.L.1    Shepard, P.D.2
  • 16
    • 0026784662 scopus 로고
    • Evidence for conditional neuronal activation following exposure to a cocaine-paired environment: role of forebrain limbic structures
    • Brown, E.E., Robertson, G.S., Fibiger, H.C., Evidence for conditional neuronal activation following exposure to a cocaine-paired environment: role of forebrain limbic structures. J. Neurosci. 12 (1992), 4112–4121.
    • (1992) J. Neurosci. , vol.12 , pp. 4112-4121
    • Brown, E.E.1    Robertson, G.S.2    Fibiger, H.C.3
  • 17
    • 78650835031 scopus 로고    scopus 로고
    • Identification of brain nuclei implicated in cocaine-primed reinstatement of conditioned place preference: a behaviour dissociable from sensitization
    • Brown, R.M., Short, J.L., Lawrence, A.J., Identification of brain nuclei implicated in cocaine-primed reinstatement of conditioned place preference: a behaviour dissociable from sensitization. PLoS One, 5, 2010, e15889.
    • (2010) PLoS One , vol.5 , pp. e15889
    • Brown, R.M.1    Short, J.L.2    Lawrence, A.J.3
  • 18
    • 0023881330 scopus 로고
    • Cerebral correlates of depressed behavior in rats, visualized using 14C-2-deoxyglucose autoradiography
    • Caldecott-Hazard, S., Mazziotta, J., Phelps, M., Cerebral correlates of depressed behavior in rats, visualized using 14C-2-deoxyglucose autoradiography. J. Neurosci. 8 (1988), 1951–1961.
    • (1988) J. Neurosci. , vol.8 , pp. 1951-1961
    • Caldecott-Hazard, S.1    Mazziotta, J.2    Phelps, M.3
  • 20
    • 0033814604 scopus 로고    scopus 로고
    • Selective neurotoxic effects of nicotine on axons in fasciculus retroflexus further support evidence that this a weak link in brain across multiple drugs of abuse
    • Carlson, J., Armstrong, B., Switzer, R.C. 3rd, Ellison, G., Selective neurotoxic effects of nicotine on axons in fasciculus retroflexus further support evidence that this a weak link in brain across multiple drugs of abuse. Neuropharmacology 39 (2000), 2792–2798.
    • (2000) Neuropharmacology , vol.39 , pp. 2792-2798
    • Carlson, J.1    Armstrong, B.2    Switzer, R.C.3    Ellison, G.4
  • 21
    • 0035816368 scopus 로고    scopus 로고
    • Nicotine produces selective degeneration in the medial habenula and fasciculus retroflexus
    • Carlson, J., Noguchi, K., Ellison, G., Nicotine produces selective degeneration in the medial habenula and fasciculus retroflexus. Brain Res. 906 (2001), 127–134.
    • (2001) Brain Res. , vol.906 , pp. 127-134
    • Carlson, J.1    Noguchi, K.2    Ellison, G.3
  • 22
    • 77956183110 scopus 로고    scopus 로고
    • Attention deficits in schizophrenia–preliminary evidence of dissociable transient and sustained deficits
    • Carter, J.D., Bizzell, J., Kim, C., Bellion, C., Carpenter, K.L., Dichter, G., Belger, A., Attention deficits in schizophrenia–preliminary evidence of dissociable transient and sustained deficits. Schizophr. Res. 122 (2010), 104–112.
    • (2010) Schizophr. Res. , vol.122 , pp. 104-112
    • Carter, J.D.1    Bizzell, J.2    Kim, C.3    Bellion, C.4    Carpenter, K.L.5    Dichter, G.6    Belger, A.7
  • 23
    • 34347230111 scopus 로고    scopus 로고
    • Processing spatial-temporal information in recent-onset schizophrenia: the study of short-term memory and its susceptibility to distraction
    • Cellard, C., Tremblay, S., Lehoux, C., Roy, M.A., Processing spatial-temporal information in recent-onset schizophrenia: the study of short-term memory and its susceptibility to distraction. Brain Cogn. 64 (2007), 201–207.
    • (2007) Brain Cogn. , vol.64 , pp. 201-207
    • Cellard, C.1    Tremblay, S.2    Lehoux, C.3    Roy, M.A.4
  • 24
    • 0022644104 scopus 로고
    • Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat
    • Christoph, G.R., Leonzio, R.J., Wilcox, K.S., Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat. J. Neurosci. 6 (1986), 613–619.
    • (1986) J. Neurosci. , vol.6 , pp. 613-619
    • Christoph, G.R.1    Leonzio, R.J.2    Wilcox, K.S.3
  • 25
    • 20344384231 scopus 로고    scopus 로고
    • Neurochemical correlates of nicotine neurotoxicity on rat habenulo-interpeduncular cholinergic neurons
    • Ciani, E., Severi, S., Bartesaghi, R., Contestabile, A., Neurochemical correlates of nicotine neurotoxicity on rat habenulo-interpeduncular cholinergic neurons. Neurotoxicology 26 (2005), 467–474.
    • (2005) Neurotoxicology , vol.26 , pp. 467-474
    • Ciani, E.1    Severi, S.2    Bartesaghi, R.3    Contestabile, A.4
  • 26
    • 0027276551 scopus 로고
    • The habenula and pain: repeated electrical stimulation produces prolonged analgesia but lesions have no effect on formalin pain or morphine analgesia
    • Cohen, S.R., Melzack, R., The habenula and pain: repeated electrical stimulation produces prolonged analgesia but lesions have no effect on formalin pain or morphine analgesia. Behav. Brain Res. 54 (1993), 171–178.
    • (1993) Behav. Brain Res. , vol.54 , pp. 171-178
    • Cohen, S.R.1    Melzack, R.2
  • 27
    • 0017255979 scopus 로고
    • Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs
    • Creese, I., Burt, D.R., Snyder, S.H., Dopamine receptor binding predicts clinical and pharmacological potencies of antischizophrenic drugs. Science 192 (1976), 481–483.
    • (1976) Science , vol.192 , pp. 481-483
    • Creese, I.1    Burt, D.R.2    Snyder, S.H.3
  • 29
    • 84896295702 scopus 로고    scopus 로고
    • Nicotine enhances excitability of medial habenular neurons via facilitation of neurokinin signaling
    • Dao, D.Q., Perez, E.E., Teng, Y., Dani, J.A., De Biasi, M., Nicotine enhances excitability of medial habenular neurons via facilitation of neurokinin signaling. J. Neurosci. 34 (2014), 4273–4284.
    • (2014) J. Neurosci. , vol.34 , pp. 4273-4284
    • Dao, D.Q.1    Perez, E.E.2    Teng, Y.3    Dani, J.A.4    De Biasi, M.5
  • 30
    • 80053141755 scopus 로고    scopus 로고
    • Patterns of brain glucose metabolism induced by phosphodiesterase 10A inhibitors in the mouse: a potential translational biomarker
    • Dedeurwaerdere, S., Wintmolders, C., Vanhoof, G., Langlois, X., Patterns of brain glucose metabolism induced by phosphodiesterase 10A inhibitors in the mouse: a potential translational biomarker. J. Pharmacol. Exp. Ther. 339 (2011), 210–217.
    • (2011) J. Pharmacol. Exp. Ther. , vol.339 , pp. 210-217
    • Dedeurwaerdere, S.1    Wintmolders, C.2    Vanhoof, G.3    Langlois, X.4
  • 31
    • 0032561707 scopus 로고    scopus 로고
    • Differential effects of clozapine and haloperidol on ketamine-induced brain metabolic activation
    • Duncan, G.E., Leipzig, J.N., Mailman, R.B., Lieberman, J.A., Differential effects of clozapine and haloperidol on ketamine-induced brain metabolic activation. Brain Res. 812 (1998), 65–75.
    • (1998) Brain Res. , vol.812 , pp. 65-75
    • Duncan, G.E.1    Leipzig, J.N.2    Mailman, R.B.3    Lieberman, J.A.4
  • 32
    • 84985931300 scopus 로고    scopus 로고
    • alpha3beta4 nicotinic receptors in the medial habenula and substance P transmission in the interpeduncular nucleus modulate nicotine sensitization
    • Eggan, B.L., McCallum, S.E., alpha3beta4 nicotinic receptors in the medial habenula and substance P transmission in the interpeduncular nucleus modulate nicotine sensitization. Behav. Brain Res. 316 (2017), 94–103.
    • (2017) Behav. Brain Res. , vol.316 , pp. 94-103
    • Eggan, B.L.1    McCallum, S.E.2
  • 33
    • 0027077973 scopus 로고
    • Continuous amphetamine and cocaine have similar neurotoxic effects in lateral habenular nucleus and fasciculus retroflexus
    • Ellison, G., Continuous amphetamine and cocaine have similar neurotoxic effects in lateral habenular nucleus and fasciculus retroflexus. Brain Res. 598 (1992), 353–356.
    • (1992) Brain Res. , vol.598 , pp. 353-356
    • Ellison, G.1
  • 34
    • 0028214032 scopus 로고
    • Stimulant-induced psychosis, the dopamine theory of schizophrenia, and the habenula
    • Ellison, G., Stimulant-induced psychosis, the dopamine theory of schizophrenia, and the habenula. Brain Res. Brain Res. Rev. 19 (1994), 223–239.
    • (1994) Brain Res. Brain Res. Rev. , vol.19 , pp. 223-239
    • Ellison, G.1
  • 36
    • 84961166836 scopus 로고    scopus 로고
    • Role of the dorsal diencephalic conduction system in the brain reward circuitry
    • Fakhoury, M., Rompre, P.P., Boye, S.M., Role of the dorsal diencephalic conduction system in the brain reward circuitry. Behav. Brain Res. 296 (2016), 431–441.
    • (2016) Behav. Brain Res. , vol.296 , pp. 431-441
    • Fakhoury, M.1    Rompre, P.P.2    Boye, S.M.3
  • 37
    • 84983411330 scopus 로고    scopus 로고
    • Effect of electrolytic lesions of the dorsal diencephalic conduction system on the distribution of Fos-like immunoreactivity induced by rewarding electrical stimulation
    • Fakhoury, M., Voyer, D., Levesque, D., Rompre, P.P., Effect of electrolytic lesions of the dorsal diencephalic conduction system on the distribution of Fos-like immunoreactivity induced by rewarding electrical stimulation. Neuroscience, 2016.
    • (2016) Neuroscience
    • Fakhoury, M.1    Voyer, D.2    Levesque, D.3    Rompre, P.P.4
  • 38
    • 84975629451 scopus 로고    scopus 로고
    • Revisiting the serotonin hypothesis: implications for major depressive disorders
    • Fakhoury, M., Revisiting the serotonin hypothesis: implications for major depressive disorders. Mol. Neurobiol., 2015.
    • (2015) Mol. Neurobiol.
    • Fakhoury, M.1
  • 40
    • 65349191920 scopus 로고    scopus 로고
    • The neurodevelopmental hypothesis of schizophrenia, revisited
    • Fatemi, S.H., Folsom, T.D., The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophr. Bull. 35 (2009), 528–548.
    • (2009) Schizophr. Bull. , vol.35 , pp. 528-548
    • Fatemi, S.H.1    Folsom, T.D.2
  • 41
    • 84884416870 scopus 로고    scopus 로고
    • Incentive motivation deficits in schizophrenia reflect effort computation impairments during cost-benefit decision-making
    • Fervaha, G., Graff-Guerrero, A., Zakzanis, K.K., Foussias, G., Agid, O., Remington, G., Incentive motivation deficits in schizophrenia reflect effort computation impairments during cost-benefit decision-making. J. Psychiatr. Res. 47 (2013), 1590–1596.
    • (2013) J. Psychiatr. Res. , vol.47 , pp. 1590-1596
    • Fervaha, G.1    Graff-Guerrero, A.2    Zakzanis, K.K.3    Foussias, G.4    Agid, O.5    Remington, G.6
  • 43
    • 79953246461 scopus 로고    scopus 로고
    • Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake
    • Fowler, C.D., Lu, Q., Johnson, P.M., Marks, M.J., Kenny, P.J., Habenular alpha5 nicotinic receptor subunit signalling controls nicotine intake. Nature 471 (2011), 597–601.
    • (2011) Nature , vol.471 , pp. 597-601
    • Fowler, C.D.1    Lu, Q.2    Johnson, P.M.3    Marks, M.J.4    Kenny, P.J.5
  • 45
    • 84955260168 scopus 로고    scopus 로고
    • An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence
    • Frahm, S., Antolin-Fontes, B., Gorlich, A., Zander, J.F., Ahnert-Hilger, G., Ibanez-Tallon, I., An essential role of acetylcholine-glutamate synergy at habenular synapses in nicotine dependence. Elife, 4, 2015, e11396.
    • (2015) Elife , vol.4 , pp. e11396
    • Frahm, S.1    Antolin-Fontes, B.2    Gorlich, A.3    Zander, J.F.4    Ahnert-Hilger, G.5    Ibanez-Tallon, I.6
  • 46
    • 0034043590 scopus 로고    scopus 로고
    • Expression of Fos-related antigens in the nucleus accumbens and associated regions following exposure to a cocaine-paired environment
    • Franklin, T.R., Druhan, J.P., Expression of Fos-related antigens in the nucleus accumbens and associated regions following exposure to a cocaine-paired environment. Eur. J. Neurosci. 12 (2000), 2097–2106.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 2097-2106
    • Franklin, T.R.1    Druhan, J.P.2
  • 47
    • 0033980031 scopus 로고    scopus 로고
    • Effects of acute and chronic treatment with fluoxetine on regional glucose cerebral metabolism in rats: implications for clinical therapies
    • Freo, U., Ori, C., Dam, M., Merico, A., Pizzolato, G., Effects of acute and chronic treatment with fluoxetine on regional glucose cerebral metabolism in rats: implications for clinical therapies. Brain Res. 854 (2000), 35–41.
    • (2000) Brain Res. , vol.854 , pp. 35-41
    • Freo, U.1    Ori, C.2    Dam, M.3    Merico, A.4    Pizzolato, G.5
  • 49
    • 85009087425 scopus 로고    scopus 로고
    • Habenula responses to potential and actual loss in major depression: preliminary evidence for lateralized dysfunction
    • Furman, D.J., Gotlib, I.H., Habenula responses to potential and actual loss in major depression: preliminary evidence for lateralized dysfunction. Soc. Cogn. Affect. Neurosci. 11 (2016), 843–851.
    • (2016) Soc. Cogn. Affect. Neurosci. , vol.11 , pp. 843-851
    • Furman, D.J.1    Gotlib, I.H.2
  • 50
    • 84907020125 scopus 로고    scopus 로고
    • Expression of mu opioid receptor in dorsal diencephalic conduction system: new insights for the medial habenula
    • Gardon, O., Faget, L., Chu Sin Chung, P., Matifas, A., Massotte, D., Kieffer, B.L., Expression of mu opioid receptor in dorsal diencephalic conduction system: new insights for the medial habenula. Neuroscience 277 (2014), 595–609.
    • (2014) Neuroscience , vol.277 , pp. 595-609
    • Gardon, O.1    Faget, L.2    Chu Sin Chung, P.3    Matifas, A.4    Massotte, D.5    Kieffer, B.L.6
  • 51
    • 0037415808 scopus 로고    scopus 로고
    • Morphologic and cytochemical criteria for the identification and delineation of individual subnuclei within the lateral habenular complex of the rat
    • Geisler, S., Andres, K.H., Veh, R.W., Morphologic and cytochemical criteria for the identification and delineation of individual subnuclei within the lateral habenular complex of the rat. J. Comp. Neurol. 458 (2003), 78–97.
    • (2003) J. Comp. Neurol. , vol.458 , pp. 78-97
    • Geisler, S.1    Andres, K.H.2    Veh, R.W.3
  • 52
    • 84865264751 scopus 로고    scopus 로고
    • Lesions of the lateral habenula dissociate the reward-enhancing and locomotor-stimulant effects of amphetamine
    • Gifuni, A.J., Jozaghi, S., Gauthier-Lamer, A.C., Boye, S.M., Lesions of the lateral habenula dissociate the reward-enhancing and locomotor-stimulant effects of amphetamine. Neuropharmacology 63 (2012), 945–957.
    • (2012) Neuropharmacology , vol.63 , pp. 945-957
    • Gifuni, A.J.1    Jozaghi, S.2    Gauthier-Lamer, A.C.3    Boye, S.M.4
  • 53
    • 84883305234 scopus 로고    scopus 로고
    • Inactivation of the lateral habenula reduces anxiogenic behavior and cocaine seeking under conditions of heightened stress
    • Gill, M.J., Ghee, S.M., Harper, S.M., See, R.E., Inactivation of the lateral habenula reduces anxiogenic behavior and cocaine seeking under conditions of heightened stress. Pharmacol. Biochem. Behav. 111 (2013), 24–29.
    • (2013) Pharmacol. Biochem. Behav. , vol.111 , pp. 24-29
    • Gill, M.J.1    Ghee, S.M.2    Harper, S.M.3    See, R.E.4
  • 54
    • 77952943087 scopus 로고    scopus 로고
    • Visual-spatial episodic memory in schizophrenia: a multiple systems framework
    • Girard, T.A., Christensen, B.K., Rizvi, S., Visual-spatial episodic memory in schizophrenia: a multiple systems framework. Neuropsychology 24 (2010), 368–378.
    • (2010) Neuropsychology , vol.24 , pp. 368-378
    • Girard, T.A.1    Christensen, B.K.2    Rizvi, S.3
  • 55
    • 33646143992 scopus 로고    scopus 로고
    • 18-Methoxycoronaridine acts in the medial habenula and/or interpeduncular nucleus to decrease morphine self-administration in rats
    • Glick, S.D., Ramirez, R.L., Livi, J.M., Maisonneuve, I.M., 18-Methoxycoronaridine acts in the medial habenula and/or interpeduncular nucleus to decrease morphine self-administration in rats. Eur. J. Pharmacol. 537 (2006), 94–98.
    • (2006) Eur. J. Pharmacol. , vol.537 , pp. 94-98
    • Glick, S.D.1    Ramirez, R.L.2    Livi, J.M.3    Maisonneuve, I.M.4
  • 56
    • 54949119069 scopus 로고    scopus 로고
    • Brain regions mediating alpha3beta4 nicotinic antagonist effects of 18-MC on methamphetamine and sucrose self-administration
    • Glick, S.D., Sell, E.M., Maisonneuve, I.M., Brain regions mediating alpha3beta4 nicotinic antagonist effects of 18-MC on methamphetamine and sucrose self-administration. Eur. J. Pharmacol. 599 (2008), 91–95.
    • (2008) Eur. J. Pharmacol. , vol.599 , pp. 91-95
    • Glick, S.D.1    Sell, E.M.2    Maisonneuve, I.M.3
  • 57
    • 80053295397 scopus 로고    scopus 로고
    • Brain regions mediating alpha3beta4 nicotinic antagonist effects of 18-MC on nicotine self-administration
    • Glick, S.D., Sell, E.M., McCallum, S.E., Maisonneuve, I.M., Brain regions mediating alpha3beta4 nicotinic antagonist effects of 18-MC on nicotine self-administration. Eur. J. Pharmacol. 669 (2011), 71–75.
    • (2011) Eur. J. Pharmacol. , vol.669 , pp. 71-75
    • Glick, S.D.1    Sell, E.M.2    McCallum, S.E.3    Maisonneuve, I.M.4
  • 58
    • 54149091651 scopus 로고    scopus 로고
    • Reward processing in schizophrenia: a deficit in the representation of value
    • Gold, J.M., Waltz, J.A., Prentice, K.J., Morris, S.E., Heerey, E.A., Reward processing in schizophrenia: a deficit in the representation of value. Schizophr. Bull. 34 (2008), 835–847.
    • (2008) Schizophr. Bull. , vol.34 , pp. 835-847
    • Gold, J.M.1    Waltz, J.A.2    Prentice, K.J.3    Morris, S.E.4    Heerey, E.A.5
  • 59
  • 60
    • 84879502269 scopus 로고    scopus 로고
    • Negative symptoms of schizophrenia are associated with abnormal effort-cost computations
    • Gold, J.M., Strauss, G.P., Waltz, J.A., Robinson, B.M., Brown, J.K., Frank, M.J., Negative symptoms of schizophrenia are associated with abnormal effort-cost computations. Biol. Psychiatry 74 (2013), 130–136.
    • (2013) Biol. Psychiatry , vol.74 , pp. 130-136
    • Gold, J.M.1    Strauss, G.P.2    Waltz, J.A.3    Robinson, B.M.4    Brown, J.K.5    Frank, M.J.6
  • 61
    • 84856710306 scopus 로고    scopus 로고
    • Differential projections from the lateral habenula to the rostromedial tegmental nucleus and ventral tegmental area in the rat
    • Goncalves, L., Sego, C., Metzger, M., Differential projections from the lateral habenula to the rostromedial tegmental nucleus and ventral tegmental area in the rat. J. Comp. Neurol. 520 (2012), 1278–1300.
    • (2012) J. Comp. Neurol. , vol.520 , pp. 1278-1300
    • Goncalves, L.1    Sego, C.2    Metzger, M.3
  • 63
    • 26444583388 scopus 로고    scopus 로고
    • Deficits on a probabilistic response-reversal task in patients with pediatric bipolar disorder
    • Gorrindo, T., Blair, R.J., Budhani, S., Dickstein, D.P., Pine, D.S., Leibenluft, E., Deficits on a probabilistic response-reversal task in patients with pediatric bipolar disorder. Am. J. Psychiatry 162 (2005), 1975–1977.
    • (2005) Am. J. Psychiatry , vol.162 , pp. 1975-1977
    • Gorrindo, T.1    Blair, R.J.2    Budhani, S.3    Dickstein, D.P.4    Pine, D.S.5    Leibenluft, E.6
  • 65
    • 84898822928 scopus 로고    scopus 로고
    • Lesions of the lateral habenula increase voluntary ethanol consumption and operant self-administration, block yohimbine-induced reinstatement of ethanol seeking, and attenuate ethanol-induced conditioned taste aversion
    • Haack, A.K., Sheth, C., Schwager, A.L., Sinclair, M.S., Tandon, S., Taha, S.A., Lesions of the lateral habenula increase voluntary ethanol consumption and operant self-administration, block yohimbine-induced reinstatement of ethanol seeking, and attenuate ethanol-induced conditioned taste aversion. PLoS One, 9, 2014, e92701.
    • (2014) PLoS One , vol.9 , pp. e92701
    • Haack, A.K.1    Sheth, C.2    Schwager, A.L.3    Sinclair, M.S.4    Tandon, S.5    Taha, S.A.6
  • 66
    • 0030870987 scopus 로고    scopus 로고
    • Amphetamine sensitization augments amphetamine-induced Fos expression in the lateral habenula
    • Hamamura, T., Ichimaru, Y., Amphetamine sensitization augments amphetamine-induced Fos expression in the lateral habenula. Brain Res. 767 (1997), 140–143.
    • (1997) Brain Res. , vol.767 , pp. 140-143
    • Hamamura, T.1    Ichimaru, Y.2
  • 67
    • 84922750573 scopus 로고    scopus 로고
    • Activation of serotonin(2C) receptors in the lateral habenular nucleus increases the expression of depression-related behaviors in the hemiparkinsonian rat
    • Han, L.N., Zhang, L., Li, L.B., Sun, Y.N., Wang, Y., Chen, L., Guo, Y., Zhang, Y.M., Zhang, Q.J., Liu, J., Activation of serotonin(2C) receptors in the lateral habenular nucleus increases the expression of depression-related behaviors in the hemiparkinsonian rat. Neuropharmacology 93 (2015), 68–79.
    • (2015) Neuropharmacology , vol.93 , pp. 68-79
    • Han, L.N.1    Zhang, L.2    Li, L.B.3    Sun, Y.N.4    Wang, Y.5    Chen, L.6    Guo, Y.7    Zhang, Y.M.8    Zhang, Q.J.9    Liu, J.10
  • 68
    • 67149099500 scopus 로고    scopus 로고
    • Sleep disturbance in bipolar disorder across the lifespan
    • Harvey, A.G., Talbot, L.S., Gershon, A., Sleep disturbance in bipolar disorder across the lifespan. Clin. Psychol. (New York) 16 (2009), 256–277.
    • (2009) Clin. Psychol. (New York) , vol.16 , pp. 256-277
    • Harvey, A.G.1    Talbot, L.S.2    Gershon, A.3
  • 69
    • 0026711209 scopus 로고
    • Habenula and thalamus cell transplants restore normal sleep behaviors disrupted by denervation of the interpeduncular nucleus
    • Haun, F., Eckenrode, T.C., Murray, M., Habenula and thalamus cell transplants restore normal sleep behaviors disrupted by denervation of the interpeduncular nucleus. J. Neurosci. 12 (1992), 3282–3290.
    • (1992) J. Neurosci. , vol.12 , pp. 3282-3290
    • Haun, F.1    Eckenrode, T.C.2    Murray, M.3
  • 70
    • 44749084127 scopus 로고    scopus 로고
    • Decision-making impairments in the context of intact reward sensitivity in schizophrenia
    • Heerey, E.A., Bell-Warren, K.R., Gold, J.M., Decision-making impairments in the context of intact reward sensitivity in schizophrenia. Biol. Psychiatry 64 (2008), 62–69.
    • (2008) Biol. Psychiatry , vol.64 , pp. 62-69
    • Heerey, E.A.1    Bell-Warren, K.R.2    Gold, J.M.3
  • 71
    • 33644935419 scopus 로고    scopus 로고
    • Lesions of the habenula produce stress- and dopamine-dependent alterations in prepulse inhibition and locomotion
    • Heldt, S.A., Ressler, K.J., Lesions of the habenula produce stress- and dopamine-dependent alterations in prepulse inhibition and locomotion. Brain Res. 1073–1074 (2006), 229–239.
    • (2006) Brain Res. , vol.1073-1074 , pp. 229-239
    • Heldt, S.A.1    Ressler, K.J.2
  • 72
    • 77953791927 scopus 로고    scopus 로고
    • The habenula: from stress evasion to value-based decision-making
    • Hikosaka, O., The habenula: from stress evasion to value-based decision-making. Nat. Rev. Neurosci. 11 (2010), 503–513.
    • (2010) Nat. Rev. Neurosci. , vol.11 , pp. 503-513
    • Hikosaka, O.1
  • 73
    • 65349120160 scopus 로고    scopus 로고
    • The dopamine hypothesis of schizophrenia: version III–the final common pathway
    • Howes, O.D., Kapur, S., The dopamine hypothesis of schizophrenia: version III–the final common pathway. Schizophr. Bull. 35 (2009), 549–562.
    • (2009) Schizophr. Bull. , vol.35 , pp. 549-562
    • Howes, O.D.1    Kapur, S.2
  • 74
    • 84906238028 scopus 로고    scopus 로고
    • Role of the dorsal medial habenula in the regulation of voluntary activity, motor function, hedonic state, and primary reinforcement
    • Hsu, Y.W., Wang, S.D., Wang, S., Morton, G., Zariwala, H.A., de la Iglesia, H.O., Turner, E.E., Role of the dorsal medial habenula in the regulation of voluntary activity, motor function, hedonic state, and primary reinforcement. J. Neurosci. 34 (2014), 11366–11384.
    • (2014) J. Neurosci. , vol.34 , pp. 11366-11384
    • Hsu, Y.W.1    Wang, S.D.2    Wang, S.3    Morton, G.4    Zariwala, H.A.5    de la Iglesia, H.O.6    Turner, E.E.7
  • 75
    • 85012987007 scopus 로고    scopus 로고
    • Dorsal medial habenula regulation of mood-related behaviors and primary reinforcement by tachykinin-expressing habenula neurons
    • Hsu, Y.W., Morton, G., Guy, E.G., Wang, S.D., Turner, E.E., Dorsal medial habenula regulation of mood-related behaviors and primary reinforcement by tachykinin-expressing habenula neurons. eNeuro, 3, 2016.
    • (2016) eNeuro , vol.3
    • Hsu, Y.W.1    Morton, G.2    Guy, E.G.3    Wang, S.D.4    Turner, E.E.5
  • 77
    • 27944489507 scopus 로고    scopus 로고
    • Comparison of alpha2 nicotinic acetylcholine receptor subunit mRNA expression in the central nervous system of rats and mice
    • Ishii, K., Wong, J.K., Sumikawa, K., Comparison of alpha2 nicotinic acetylcholine receptor subunit mRNA expression in the central nervous system of rats and mice. J. Comp. Neurol. 493 (2005), 241–260.
    • (2005) J. Comp. Neurol. , vol.493 , pp. 241-260
    • Ishii, K.1    Wong, J.K.2    Sumikawa, K.3
  • 78
    • 83055184338 scopus 로고    scopus 로고
    • Propensity to ‘relapse' following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei
    • James, M.H., Charnley, J.L., Flynn, J.R., Smith, D.W., Dayas, C.V., Propensity to ‘relapse' following exposure to cocaine cues is associated with the recruitment of specific thalamic and epithalamic nuclei. Neuroscience 199 (2011), 235–242.
    • (2011) Neuroscience , vol.199 , pp. 235-242
    • James, M.H.1    Charnley, J.L.2    Flynn, J.R.3    Smith, D.W.4    Dayas, C.V.5
  • 79
    • 61549142101 scopus 로고    scopus 로고
    • The mesopontine rostromedial tegmental nucleus: a structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta
    • Jhou, T.C., Geisler, S., Marinelli, M., Degarmo, B.A., Zahm, D.S., The mesopontine rostromedial tegmental nucleus: a structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta. J. Comp. Neurol. 513 (2009), 566–596.
    • (2009) J. Comp. Neurol. , vol.513 , pp. 566-596
    • Jhou, T.C.1    Geisler, S.2    Marinelli, M.3    Degarmo, B.A.4    Zahm, D.S.5
  • 80
    • 84876526512 scopus 로고    scopus 로고
    • Cocaine drives aversive conditioning via delayed activation of dopamine-responsive habenular and midbrain pathways
    • Jhou, T.C., Good, C.H., Rowley, C.S., Xu, S.P., Wang, H., Burnham, N.W., Hoffman, A.F., Lupica, C.R., Ikemoto, S., Cocaine drives aversive conditioning via delayed activation of dopamine-responsive habenular and midbrain pathways. J. Neurosci. 33 (2013), 7501–7512.
    • (2013) J. Neurosci. , vol.33 , pp. 7501-7512
    • Jhou, T.C.1    Good, C.H.2    Rowley, C.S.3    Xu, S.P.4    Wang, H.5    Burnham, N.W.6    Hoffman, A.F.7    Lupica, C.R.8    Ikemoto, S.9
  • 81
    • 34347324115 scopus 로고    scopus 로고
    • Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABA(A) receptor-mediated mechanism
    • Ji, H., Shepard, P.D., Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABA(A) receptor-mediated mechanism. J. Neurosci. 27 (2007), 6923–6930.
    • (2007) J. Neurosci. , vol.27 , pp. 6923-6930
    • Ji, H.1    Shepard, P.D.2
  • 82
    • 0024333177 scopus 로고
    • Regulation of striatal serotonin release by the lateral habenula-dorsal raphe pathway in the rat as demonstrated by in vivo microdialysis: role of excitatory amino acids and GABA
    • Kalen, P., Strecker, R.E., Rosengren, E., Bjorklund, A., Regulation of striatal serotonin release by the lateral habenula-dorsal raphe pathway in the rat as demonstrated by in vivo microdialysis: role of excitatory amino acids and GABA. Brain Res. 492 (1989), 187–202.
    • (1989) Brain Res. , vol.492 , pp. 187-202
    • Kalen, P.1    Strecker, R.E.2    Rosengren, E.3    Bjorklund, A.4
  • 84
    • 0032886356 scopus 로고    scopus 로고
    • Long-term alterations in benzodiazepine, muscarinic and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor density following continuous cocaine administration
    • Keys, A.S., Ellison, G.D., Long-term alterations in benzodiazepine, muscarinic and alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor density following continuous cocaine administration. Pharmacol. Toxicol. 85 (1999), 144–150.
    • (1999) Pharmacol. Toxicol. , vol.85 , pp. 144-150
    • Keys, A.S.1    Ellison, G.D.2
  • 85
    • 84881521450 scopus 로고    scopus 로고
    • A new translational target for deep brain stimulation to treat depression
    • Kiening, K., Sartorius, A., A new translational target for deep brain stimulation to treat depression. EMBO Mol. Med. 5 (2013), 1151–1153.
    • (2013) EMBO Mol. Med. , vol.5 , pp. 1151-1153
    • Kiening, K.1    Sartorius, A.2
  • 86
    • 84962262579 scopus 로고    scopus 로고
    • Antidepressant actions of lateral habenula deep brain stimulation differentially correlate with CaMKII/GSK3/AMPK signaling locally and in the infralimbic cortex
    • Kim, Y., Morath, B., Hu, C., Byrne, L.K., Sutor, S.L., Frye, M.A., Tye, S.J., Antidepressant actions of lateral habenula deep brain stimulation differentially correlate with CaMKII/GSK3/AMPK signaling locally and in the infralimbic cortex. Behav. Brain Res. 306 (2016), 170–177.
    • (2016) Behav. Brain Res. , vol.306 , pp. 170-177
    • Kim, Y.1    Morath, B.2    Hu, C.3    Byrne, L.K.4    Sutor, S.L.5    Frye, M.A.6    Tye, S.J.7
  • 87
    • 0025234880 scopus 로고
    • Clonidine attenuates increased brain glucose metabolism during naloxone-precipitated morphine withdrawal
    • Kimes, A.S., Bell, J.A., London, E.D., Clonidine attenuates increased brain glucose metabolism during naloxone-precipitated morphine withdrawal. Neuroscience 34 (1990), 633–644.
    • (1990) Neuroscience , vol.34 , pp. 633-644
    • Kimes, A.S.1    Bell, J.A.2    London, E.D.3
  • 88
    • 0030756351 scopus 로고    scopus 로고
    • Drug abuse: hedonic homeostatic dysregulation
    • Koob, G.F., Le Moal, M., Drug abuse: hedonic homeostatic dysregulation. Science 278 (1997), 52–58.
    • (1997) Science , vol.278 , pp. 52-58
    • Koob, G.F.1    Le Moal, M.2
  • 89
    • 0035199891 scopus 로고    scopus 로고
    • Drug addiction, dysregulation of reward, and allostasis
    • Koob, G.F., Le Moal, M., Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology 24 (2001), 97–129.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 97-129
    • Koob, G.F.1    Le Moal, M.2
  • 90
    • 67949109749 scopus 로고    scopus 로고
    • The neurobiology of addiction: where we have been and where we are going
    • Koob, G.F., Simon, E.J., The neurobiology of addiction: where we have been and where we are going. J. Drug Issues 39 (2009), 115–132.
    • (2009) J. Drug Issues , vol.39 , pp. 115-132
    • Koob, G.F.1    Simon, E.J.2
  • 91
    • 84884471807 scopus 로고    scopus 로고
    • Addiction is a reward deficit and stress surfeit disorder
    • Koob, G.F., Addiction is a reward deficit and stress surfeit disorder. Front. Psychiatry, 4, 2013, 72.
    • (2013) Front. Psychiatry , vol.4 , pp. 72
    • Koob, G.F.1
  • 92
    • 74649086556 scopus 로고    scopus 로고
    • Impaired decision making in schizophrenia and orbitofrontal cortex lesion patients
    • Larquet, M., Coricelli, G., Opolczynski, G., Thibaut, F., Impaired decision making in schizophrenia and orbitofrontal cortex lesion patients. Schizophr. Res. 116 (2010), 266–273.
    • (2010) Schizophr. Res. , vol.116 , pp. 266-273
    • Larquet, M.1    Coricelli, G.2    Opolczynski, G.3    Thibaut, F.4
  • 93
    • 77955074534 scopus 로고    scopus 로고
    • Early signs, diagnosis and therapeutics of the prodromal phase of schizophrenia and related psychotic disorders
    • Larson, M.K., Walker, E.F., Compton, M.T., Early signs, diagnosis and therapeutics of the prodromal phase of schizophrenia and related psychotic disorders. Expert Rev. Neurother. 10 (2010), 1347–1359.
    • (2010) Expert Rev. Neurother. , vol.10 , pp. 1347-1359
    • Larson, M.K.1    Walker, E.F.2    Compton, M.T.3
  • 96
    • 84955603006 scopus 로고    scopus 로고
    • Rescue of GABAB and GIRK function in the lateral habenula by protein phosphatase 2A inhibition ameliorates depression-like phenotypes in mice
    • Lecca, S., Pelosi, A., Tchenio, A., Moutkine, I., Lujan, R., Herve, D., Mameli, M., Rescue of GABAB and GIRK function in the lateral habenula by protein phosphatase 2A inhibition ameliorates depression-like phenotypes in mice. Nat. Med. 22 (2016), 254–261.
    • (2016) Nat. Med. , vol.22 , pp. 254-261
    • Lecca, S.1    Pelosi, A.2    Tchenio, A.3    Moutkine, I.4    Lujan, R.5    Herve, D.6    Mameli, M.7
  • 97
    • 13944278877 scopus 로고    scopus 로고
    • Bilateral lesions of the habenula induce attentional disturbances in rats
    • Lecourtier, L., Kelly, P.H., Bilateral lesions of the habenula induce attentional disturbances in rats. Neuropsychopharmacology 30 (2005), 484–496.
    • (2005) Neuropsychopharmacology , vol.30 , pp. 484-496
    • Lecourtier, L.1    Kelly, P.H.2
  • 98
    • 34247637934 scopus 로고    scopus 로고
    • A conductor hidden in the orchestra? Role of the habenular complex in monoamine transmission and cognition
    • Lecourtier, L., Kelly, P.H., A conductor hidden in the orchestra? Role of the habenular complex in monoamine transmission and cognition. Neurosci. Biobehav. Rev. 31 (2007), 658–672.
    • (2007) Neurosci. Biobehav. Rev. , vol.31 , pp. 658-672
    • Lecourtier, L.1    Kelly, P.H.2
  • 99
    • 2442587637 scopus 로고    scopus 로고
    • Habenula lesions cause impaired cognitive performance in rats: implications for schizophrenia
    • Lecourtier, L., Neijt, H.C., Kelly, P.H., Habenula lesions cause impaired cognitive performance in rats: implications for schizophrenia. Eur. J. Neurosci. 19 (2004), 2551–2560.
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 2551-2560
    • Lecourtier, L.1    Neijt, H.C.2    Kelly, P.H.3
  • 100
    • 33746001393 scopus 로고    scopus 로고
    • Habenula lesions alter synaptic plasticity within the fimbria-accumbens pathway in the rat
    • Lecourtier, L., Deschaux, O., Arnaud, C., Chessel, A., Kelly, P.H., Garcia, R., Habenula lesions alter synaptic plasticity within the fimbria-accumbens pathway in the rat. Neuroscience 141 (2006), 1025–1032.
    • (2006) Neuroscience , vol.141 , pp. 1025-1032
    • Lecourtier, L.1    Deschaux, O.2    Arnaud, C.3    Chessel, A.4    Kelly, P.H.5    Garcia, R.6
  • 101
    • 84881648871 scopus 로고    scopus 로고
    • Habenula and ADHD: convergence on time
    • Lee, Y.A., Goto, Y., Habenula and ADHD: convergence on time. Neurosci. Biobehav. Rev. 37 (2013), 1801–1809.
    • (2013) Neurosci. Biobehav. Rev. , vol.37 , pp. 1801-1809
    • Lee, Y.A.1    Goto, Y.2
  • 102
    • 0023766722 scopus 로고
    • Role of lateral habenula in the regulation of exploratory behavior and its relationship to stress in rats
    • Lee, E.H., Huang, S.L., Role of lateral habenula in the regulation of exploratory behavior and its relationship to stress in rats. Behav. Brain Res. 30 (1988), 265–271.
    • (1988) Behav. Brain Res. , vol.30 , pp. 265-271
    • Lee, E.H.1    Huang, S.L.2
  • 103
    • 79952129505 scopus 로고    scopus 로고
    • Synaptic potentiation onto habenula neurons in the learned helplessness model of depression
    • Li, B., Piriz, J., Mirrione, M., Chung, C., Proulx, C.D., Schulz, D., Henn, F., Malinow, R., Synaptic potentiation onto habenula neurons in the learned helplessness model of depression. Nature 470 (2011), 535–539.
    • (2011) Nature , vol.470 , pp. 535-539
    • Li, B.1    Piriz, J.2    Mirrione, M.3    Chung, C.4    Proulx, C.D.5    Schulz, D.6    Henn, F.7    Malinow, R.8
  • 104
  • 105
    • 0034284828 scopus 로고    scopus 로고
    • To model a psychiatric disorder in animals: schizophrenia as a reality test
    • Lipska, B.K., Weinberger, D.R., To model a psychiatric disorder in animals: schizophrenia as a reality test. Neuropsychopharmacology 23 (2000), 223–239.
    • (2000) Neuropsychopharmacology , vol.23 , pp. 223-239
    • Lipska, B.K.1    Weinberger, D.R.2
  • 106
    • 0022468144 scopus 로고
    • Effects of L-cocaine on local cerebral glucose utilization in the rat
    • London, E.D., Wilkerson, G., Goldberg, S.R., Risner, M.E., Effects of L-cocaine on local cerebral glucose utilization in the rat. Neurosci. Lett. 68 (1986), 73–78.
    • (1986) Neurosci. Lett. , vol.68 , pp. 73-78
    • London, E.D.1    Wilkerson, G.2    Goldberg, S.R.3    Risner, M.E.4
  • 107
    • 84918833202 scopus 로고    scopus 로고
    • Lateral habenula as a link between dopaminergic and serotonergic systems contributes to depressive symptoms in Parkinson's disease
    • Luo, X.F., Zhang, B.L., Li, J.C., Yang, Y.Y., Sun, Y.F., Zhao, H., Lateral habenula as a link between dopaminergic and serotonergic systems contributes to depressive symptoms in Parkinson's disease. Brain Res. Bull. 110 (2015), 40–46.
    • (2015) Brain Res. Bull. , vol.110 , pp. 40-46
    • Luo, X.F.1    Zhang, B.L.2    Li, J.C.3    Yang, Y.Y.4    Sun, Y.F.5    Zhao, H.6
  • 108
    • 84966713297 scopus 로고    scopus 로고
    • High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats
    • Madularu, D., Kulkarni, P., Yee, J.R., Kenkel, W.M., Shams, W.M., Ferris, C.F., Brake, W.G., High estrogen and chronic haloperidol lead to greater amphetamine-induced BOLD activation in awake, amphetamine-sensitized female rats. Horm. Behav. 82 (2016), 56–63.
    • (2016) Horm. Behav. , vol.82 , pp. 56-63
    • Madularu, D.1    Kulkarni, P.2    Yee, J.R.3    Kenkel, W.M.4    Shams, W.M.5    Ferris, C.F.6    Brake, W.G.7
  • 109
    • 84866395309 scopus 로고    scopus 로고
    • Fos activation of selective afferents to ventral tegmental area during cue-induced reinstatement of cocaine seeking in rats
    • Mahler, S.V., Aston-Jones, G.S., Fos activation of selective afferents to ventral tegmental area during cue-induced reinstatement of cocaine seeking in rats. J. Neurosci. 32 (2012), 13309–13326.
    • (2012) J. Neurosci. , vol.32 , pp. 13309-13326
    • Mahler, S.V.1    Aston-Jones, G.S.2
  • 111
    • 84865793096 scopus 로고    scopus 로고
    • Cocaine evokes projection-specific synaptic plasticity of lateral habenula neurons
    • Maroteaux, M., Mameli, M., Cocaine evokes projection-specific synaptic plasticity of lateral habenula neurons. J. Neurosci. 32 (2012), 12641–12646.
    • (2012) J. Neurosci. , vol.32 , pp. 12641-12646
    • Maroteaux, M.1    Mameli, M.2
  • 113
    • 84944354672 scopus 로고    scopus 로고
    • Excitatory transmission to the lateral habenula is critical for encoding and retrieval of spatial memory
    • Mathis, V., Cosquer, B., Avallone, M., Cassel, J.C., Lecourtier, L., Excitatory transmission to the lateral habenula is critical for encoding and retrieval of spatial memory. Neuropsychopharmacology 40 (2015), 2843–2851.
    • (2015) Neuropsychopharmacology , vol.40 , pp. 2843-2851
    • Mathis, V.1    Cosquer, B.2    Avallone, M.3    Cassel, J.C.4    Lecourtier, L.5
  • 114
    • 34347343926 scopus 로고    scopus 로고
    • Lateral habenula as a source of negative reward signals in dopamine neurons
    • Matsumoto, M., Hikosaka, O., Lateral habenula as a source of negative reward signals in dopamine neurons. Nature 447 (2007), 1111–1115.
    • (2007) Nature , vol.447 , pp. 1111-1115
    • Matsumoto, M.1    Hikosaka, O.2
  • 115
    • 0029618025 scopus 로고
    • Lateral habenula neurons are necessary for the hormonal onset of maternal behavior and for the display of postpartum estrus in naturally parturient female rats
    • Matthews-Felton, T., Corodimas, K.P., Rosenblatt, J.S., Morrell, J.I., Lateral habenula neurons are necessary for the hormonal onset of maternal behavior and for the display of postpartum estrus in naturally parturient female rats. Behav. Neurosci. 109 (1995), 1172–1188.
    • (1995) Behav. Neurosci. , vol.109 , pp. 1172-1188
    • Matthews-Felton, T.1    Corodimas, K.P.2    Rosenblatt, J.S.3    Morrell, J.I.4
  • 116
    • 84862023229 scopus 로고    scopus 로고
    • alpha3beta4 nicotinic acetylcholine receptors in the medial habenula modulate the mesolimbic dopaminergic response to acute nicotine in vivo
    • McCallum, S.E., Cowe, M.A., Lewis, S.W., Glick, S.D., alpha3beta4 nicotinic acetylcholine receptors in the medial habenula modulate the mesolimbic dopaminergic response to acute nicotine in vivo. Neuropharmacology 63 (2012), 434–440.
    • (2012) Neuropharmacology , vol.63 , pp. 434-440
    • McCallum, S.E.1    Cowe, M.A.2    Lewis, S.W.3    Glick, S.D.4
  • 117
    • 62649105874 scopus 로고    scopus 로고
    • Emotional reactivity in depression: diminished responsiveness to anticipated reward but not to anticipated punishment or to nonreward or avoidance
    • McFarland, B.R., Klein, D.N., Emotional reactivity in depression: diminished responsiveness to anticipated reward but not to anticipated punishment or to nonreward or avoidance. Depress. Anxiety 26 (2009), 117–122.
    • (2009) Depress. Anxiety , vol.26 , pp. 117-122
    • McFarland, B.R.1    Klein, D.N.2
  • 118
    • 80054868141 scopus 로고    scopus 로고
    • Chronic deep brain stimulation of the lateral habenula nucleus in a rat model of depression
    • Meng, H., Wang, Y., Huang, M., Lin, W., Wang, S., Zhang, B., Chronic deep brain stimulation of the lateral habenula nucleus in a rat model of depression. Brain Res. 1422 (2011), 32–38.
    • (2011) Brain Res. , vol.1422 , pp. 32-38
    • Meng, H.1    Wang, Y.2    Huang, M.3    Lin, W.4    Wang, S.5    Zhang, B.6
  • 119
    • 0031866904 scopus 로고    scopus 로고
    • Cocaine-induced changes in glutamate and GABA immunolabeling within rat habenula and nucleus accumbens
    • Meshul, C.K., Noguchi, K., Emre, N., Ellison, G., Cocaine-induced changes in glutamate and GABA immunolabeling within rat habenula and nucleus accumbens. Synapse 30 (1998), 211–220.
    • (1998) Synapse , vol.30 , pp. 211-220
    • Meshul, C.K.1    Noguchi, K.2    Emre, N.3    Ellison, G.4
  • 121
    • 84893262308 scopus 로고    scopus 로고
    • Increased metabolic activity in the septum and habenula during stress is linked to subsequent expression of learned helplessness behavior
    • Mirrione, M.M., Schulz, D., Lapidus, K.A., Zhang, S., Goodman, W., Henn, F.A., Increased metabolic activity in the septum and habenula during stress is linked to subsequent expression of learned helplessness behavior. Front. Hum. Neurosci., 8, 2014, 29.
    • (2014) Front. Hum. Neurosci. , vol.8 , pp. 29
    • Mirrione, M.M.1    Schulz, D.2    Lapidus, K.A.3    Zhang, S.4    Goodman, W.5    Henn, F.A.6
  • 122
    • 0020964382 scopus 로고
    • Acetylcholinesterase changes in the central nervous system of mice during the development of morphine tolerance addiction and withdrawal
    • Mohanakumar, K.P., Sood, P.P., Acetylcholinesterase changes in the central nervous system of mice during the development of morphine tolerance addiction and withdrawal. Brain Res. Bull. 10 (1983), 589–596.
    • (1983) Brain Res. Bull. , vol.10 , pp. 589-596
    • Mohanakumar, K.P.1    Sood, P.P.2
  • 123
    • 84905575488 scopus 로고    scopus 로고
    • Deep brain stimulation for treatment-resistant depression: systematic review of clinical outcomes
    • Morishita, T., Fayad, S.M., Higuchi, M.A., Nestor, K.A., Foote, K.D., Deep brain stimulation for treatment-resistant depression: systematic review of clinical outcomes. Neurotherapeutics 11 (2014), 475–484.
    • (2014) Neurotherapeutics , vol.11 , pp. 475-484
    • Morishita, T.1    Fayad, S.M.2    Higuchi, M.A.3    Nestor, K.A.4    Foote, K.D.5
  • 124
    • 36749009602 scopus 로고    scopus 로고
    • Electrolytic lesions of the habenula attenuate brain stimulation reward
    • Morissette, M.C., Boye, S.M., Electrolytic lesions of the habenula attenuate brain stimulation reward. Behav. Brain Res. 187 (2008), 17–26.
    • (2008) Behav. Brain Res. , vol.187 , pp. 17-26
    • Morissette, M.C.1    Boye, S.M.2
  • 125
    • 0033178606 scopus 로고    scopus 로고
    • Covariation of activity in habenula and dorsal raphe nuclei following tryptophan depletion
    • Morris, J.S., Smith, K.A., Cowen, P.J., Friston, K.J., Dolan, R.J., Covariation of activity in habenula and dorsal raphe nuclei following tryptophan depletion. Neuroimage 10 (1999), 163–172.
    • (1999) Neuroimage , vol.10 , pp. 163-172
    • Morris, J.S.1    Smith, K.A.2    Cowen, P.J.3    Friston, K.J.4    Dolan, R.J.5
  • 126
    • 0030297281 scopus 로고    scopus 로고
    • Lesion of the habenular efferent pathway produces anxiety and locomotor hyperactivity in rats: a comparison of the effects of neonatal and adult lesions
    • Murphy, C.A., DiCamillo, A.M., Haun, F., Murray, M., Lesion of the habenular efferent pathway produces anxiety and locomotor hyperactivity in rats: a comparison of the effects of neonatal and adult lesions. Behav. Brain Res. 81 (1996), 43–52.
    • (1996) Behav. Brain Res. , vol.81 , pp. 43-52
    • Murphy, C.A.1    DiCamillo, A.M.2    Haun, F.3    Murray, M.4
  • 127
    • 0034636497 scopus 로고    scopus 로고
    • Rewarding effects of opiates are absent in mice lacking the receptor for substance P
    • Murtra, P., Sheasby, A.M., Hunt, S.P., De Felipe, C., Rewarding effects of opiates are absent in mice lacking the receptor for substance P. Nature 405 (2000), 180–183.
    • (2000) Nature , vol.405 , pp. 180-183
    • Murtra, P.1    Sheasby, A.M.2    Hunt, S.P.3    De Felipe, C.4
  • 128
    • 84871620525 scopus 로고    scopus 로고
    • Psychiatric disorder-related abnormal behavior and habenulointerpeduncular pathway defects in Wnt1-cre and Wnt1-GAL4 double transgenic mice
    • Nakajima, M., Mori, H., Nishikawa, C., Tsuruta, M., Okuyama, S., Furukawa, Y., Psychiatric disorder-related abnormal behavior and habenulointerpeduncular pathway defects in Wnt1-cre and Wnt1-GAL4 double transgenic mice. J. Neurochem. 124 (2013), 241–249.
    • (2013) J. Neurochem. , vol.124 , pp. 241-249
    • Nakajima, M.1    Mori, H.2    Nishikawa, C.3    Tsuruta, M.4    Okuyama, S.5    Furukawa, Y.6
  • 131
    • 55449136712 scopus 로고    scopus 로고
    • Sleep disorders as core symptoms of depression
    • Nutt, D., Wilson, S., Paterson, L., Sleep disorders as core symptoms of depression. Dialogues Clin. Neurosci. 10 (2008), 329–336.
    • (2008) Dialogues Clin. Neurosci. , vol.10 , pp. 329-336
    • Nutt, D.1    Wilson, S.2    Paterson, L.3
  • 132
    • 70350437997 scopus 로고    scopus 로고
    • Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area
    • Omelchenko, N., Bell, R., Sesack, S.R., Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area. Eur. J. Neurosci. 30 (2009), 1239–1250.
    • (2009) Eur. J. Neurosci. , vol.30 , pp. 1239-1250
    • Omelchenko, N.1    Bell, R.2    Sesack, S.R.3
  • 134
    • 28044434214 scopus 로고    scopus 로고
    • Attenuation of morphine withdrawal signs by intracerebral administration of 18-methoxycoronaridine
    • Panchal, V., Taraschenko, O.D., Maisonneuve, I.M., Glick, S.D., Attenuation of morphine withdrawal signs by intracerebral administration of 18-methoxycoronaridine. Eur. J. Pharmacol. 525 (2005), 98–104.
    • (2005) Eur. J. Pharmacol. , vol.525 , pp. 98-104
    • Panchal, V.1    Taraschenko, O.D.2    Maisonneuve, I.M.3    Glick, S.D.4
  • 137
    • 52949118493 scopus 로고    scopus 로고
    • Reduced hedonic capacity in major depressive disorder: evidence from a probabilistic reward task
    • Pizzagalli, D.A., Iosifescu, D., Hallett, L.A., Ratner, K.G., Fava, M., Reduced hedonic capacity in major depressive disorder: evidence from a probabilistic reward task. J. Psychiatr. Res. 43 (2008), 76–87.
    • (2008) J. Psychiatr. Res. , vol.43 , pp. 76-87
    • Pizzagalli, D.A.1    Iosifescu, D.2    Hallett, L.A.3    Ratner, K.G.4    Fava, M.5
  • 139
    • 0021280450 scopus 로고
    • Haloperidol and cerebral metabolism in the conscious rat: relation to pharmacokinetics
    • Pizzolato, G., Soncrant, T.T., Rapoport, S.I., Haloperidol and cerebral metabolism in the conscious rat: relation to pharmacokinetics. J. Neurochem. 43 (1984), 724–732.
    • (1984) J. Neurochem. , vol.43 , pp. 724-732
    • Pizzolato, G.1    Soncrant, T.T.2    Rapoport, S.I.3
  • 140
    • 0024272571 scopus 로고
    • Selective alterations in cerebral metabolism within the mesocorticolimbic dopaminergic system produced by acute cocaine administration in rats
    • Porrino, L.J., Domer, F.R., Crane, A.M., Sokoloff, L., Selective alterations in cerebral metabolism within the mesocorticolimbic dopaminergic system produced by acute cocaine administration in rats. Neuropsychopharmacology 1 (1988), 109–118.
    • (1988) Neuropsychopharmacology , vol.1 , pp. 109-118
    • Porrino, L.J.1    Domer, F.R.2    Crane, A.M.3    Sokoloff, L.4
  • 141
    • 84906674545 scopus 로고    scopus 로고
    • Reward processing by the lateral habenula in normal and depressive behaviors
    • Proulx, C.D., Hikosaka, O., Malinow, R., Reward processing by the lateral habenula in normal and depressive behaviors. Nat. Neurosci. 17 (2014), 1146–1152.
    • (2014) Nat. Neurosci. , vol.17 , pp. 1146-1152
    • Proulx, C.D.1    Hikosaka, O.2    Malinow, R.3
  • 142
    • 77952423760 scopus 로고    scopus 로고
    • Evidence for structural abnormalities of the human habenular complex in affective disorders but not in schizophrenia
    • Ranft, K., Dobrowolny, H., Krell, D., Bielau, H., Bogerts, B., Bernstein, H.G., Evidence for structural abnormalities of the human habenular complex in affective disorders but not in schizophrenia. Psychol. Med. 40 (2010), 557–567.
    • (2010) Psychol. Med. , vol.40 , pp. 557-567
    • Ranft, K.1    Dobrowolny, H.2    Krell, D.3    Bielau, H.4    Bogerts, B.5    Bernstein, H.G.6
  • 143
    • 0020461179 scopus 로고
    • Involvement of lateral habenula-dorsal raphe neurons in the differential regulation of striatal and nigral serotonergic transmission cats
    • Reisine, T.D., Soubrie, P., Artaud, F., Glowinski, J., Involvement of lateral habenula-dorsal raphe neurons in the differential regulation of striatal and nigral serotonergic transmission cats. J. Neurosci. 2 (1982), 1062–1071.
    • (1982) J. Neurosci. , vol.2 , pp. 1062-1071
    • Reisine, T.D.1    Soubrie, P.2    Artaud, F.3    Glowinski, J.4
  • 144
    • 0036951193 scopus 로고    scopus 로고
    • Lack of self-administration and behavioural sensitisation to morphine, but not cocaine, in mice lacking NK1 receptors
    • Ripley, T.L., Gadd, C.A., De Felipe, C., Hunt, S.P., Stephens, D.N., Lack of self-administration and behavioural sensitisation to morphine, but not cocaine, in mice lacking NK1 receptors. Neuropharmacology 43 (2002), 1258–1268.
    • (2002) Neuropharmacology , vol.43 , pp. 1258-1268
    • Ripley, T.L.1    Gadd, C.A.2    De Felipe, C.3    Hunt, S.P.4    Stephens, D.N.5
  • 146
    • 0025718829 scopus 로고
    • The effect of the potential antipsychotic ORG 5222 on local cerebral glucose utilization in freely moving rats
    • Room, P., Tielemans, A.J., De Boer, T., Van Delft, A.M., Tonnaer, J.A., The effect of the potential antipsychotic ORG 5222 on local cerebral glucose utilization in freely moving rats. Eur. J. Pharmacol. 205 (1991), 233–240.
    • (1991) Eur. J. Pharmacol. , vol.205 , pp. 233-240
    • Room, P.1    Tielemans, A.J.2    De Boer, T.3    Van Delft, A.M.4    Tonnaer, J.A.5
  • 147
    • 0013893886 scopus 로고
    • The significance of dopamine-receptor blockade for the mechanism of action of neuroleptic drugs
    • van Rossum, J.M., The significance of dopamine-receptor blockade for the mechanism of action of neuroleptic drugs. Arch. Int. Pharmacodyn. Ther. 160 (1966), 492–494.
    • (1966) Arch. Int. Pharmacodyn. Ther. , vol.160 , pp. 492-494
    • van Rossum, J.M.1
  • 148
    • 77957366301 scopus 로고    scopus 로고
    • Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD
    • Saccone, N.L., et al. Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet., 2010, 6.
    • (2010) PLoS Genet. , pp. 6
    • Saccone, N.L.1
  • 149
    • 8544262943 scopus 로고    scopus 로고
    • Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit
    • Salas, R., Pieri, F., De Biasi, M., Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit. J. Neurosci. 24 (2004), 10035–10039.
    • (2004) J. Neurosci. , vol.24 , pp. 10035-10039
    • Salas, R.1    Pieri, F.2    De Biasi, M.3
  • 150
    • 63849115116 scopus 로고    scopus 로고
    • Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice
    • Salas, R., Sturm, R., Boulter, J., De Biasi, M., Nicotinic receptors in the habenulo-interpeduncular system are necessary for nicotine withdrawal in mice. J. Neurosci. 29 (2009), 3014–3018.
    • (2009) J. Neurosci. , vol.29 , pp. 3014-3018
    • Salas, R.1    Sturm, R.2    Boulter, J.3    De Biasi, M.4
  • 151
    • 77953472230 scopus 로고    scopus 로고
    • BOLD responses to negative reward prediction errors in human habenula
    • Salas, R., Baldwin, P., de Biasi, M., Montague, P.R., BOLD responses to negative reward prediction errors in human habenula. Front. Hum. Neurosci., 4, 2010, 36.
    • (2010) Front. Hum. Neurosci. , vol.4 , pp. 36
    • Salas, R.1    Baldwin, P.2    de Biasi, M.3    Montague, P.R.4
  • 152
    • 0026297519 scopus 로고
    • Relevance of the habenular complex to neuropsychiatry: a review and hypothesis
    • Sandyk, R., Relevance of the habenular complex to neuropsychiatry: a review and hypothesis. Int. J. Neurosci. 61 (1991), 189–219.
    • (1991) Int. J. Neurosci. , vol.61 , pp. 189-219
    • Sandyk, R.1
  • 153
    • 0026951246 scopus 로고
    • Pineal and habenula calcification in schizophrenia
    • Sandyk, R., Pineal and habenula calcification in schizophrenia. Int. J. Neurosci. 67 (1992), 19–30.
    • (1992) Int. J. Neurosci. , vol.67 , pp. 19-30
    • Sandyk, R.1
  • 154
    • 35448951377 scopus 로고    scopus 로고
    • Deep brain stimulation of the lateral habenula in treatment resistant major depression
    • Sartorius, A., Henn, F.A., Deep brain stimulation of the lateral habenula in treatment resistant major depression. Med. Hypotheses 69 (2007), 1305–1308.
    • (2007) Med. Hypotheses , vol.69 , pp. 1305-1308
    • Sartorius, A.1    Henn, F.A.2
  • 158
    • 0031867046 scopus 로고    scopus 로고
    • Predictive reward signal of dopamine neurons
    • Schultz, W., Predictive reward signal of dopamine neurons. J. Neurophysiol. 80 (1998), 1–27.
    • (1998) J. Neurophysiol. , vol.80 , pp. 1-27
    • Schultz, W.1
  • 159
    • 0036221550 scopus 로고    scopus 로고
    • Atypical antipsychotics: mechanism of action
    • Seeman, P., Atypical antipsychotics: mechanism of action. Can. J. Psychiatry 47 (2002), 27–38.
    • (2002) Can. J. Psychiatry , vol.47 , pp. 27-38
    • Seeman, P.1
  • 160
    • 84860678825 scopus 로고    scopus 로고
    • Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin
    • Shabel, S.J., Proulx, C.D., Trias, A., Murphy, R.T., Malinow, R., Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin. Neuron 74 (2012), 475–481.
    • (2012) Neuron , vol.74 , pp. 475-481
    • Shabel, S.J.1    Proulx, C.D.2    Trias, A.3    Murphy, R.T.4    Malinow, R.5
  • 161
    • 84907192039 scopus 로고    scopus 로고
    • Mood regulation. GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment
    • Shabel, S.J., Proulx, C.D., Piriz, J., Malinow, R., Mood regulation. GABA/glutamate co-release controls habenula output and is modified by antidepressant treatment. Science 345 (2014), 1494–1498.
    • (2014) Science , vol.345 , pp. 1494-1498
    • Shabel, S.J.1    Proulx, C.D.2    Piriz, J.3    Malinow, R.4
  • 162
    • 0033819579 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor subunit mRNA expression and channel function in medial habenula neurons
    • Sheffield, E.B., Quick, M.W., Lester, R.A., Nicotinic acetylcholine receptor subunit mRNA expression and channel function in medial habenula neurons. Neuropharmacology 39 (2000), 2591–2603.
    • (2000) Neuropharmacology , vol.39 , pp. 2591-2603
    • Sheffield, E.B.1    Quick, M.W.2    Lester, R.A.3
  • 163
    • 33745594568 scopus 로고    scopus 로고
    • Schizophrenia in translation: the presence of absence: habenular regulation of dopamine neurons and the encoding of negative outcomes
    • Shepard, P.D., Holcomb, H.H., Gold, J.M., Schizophrenia in translation: the presence of absence: habenular regulation of dopamine neurons and the encoding of negative outcomes. Schizophr. Bull. 32 (2006), 417–421.
    • (2006) Schizophr. Bull. , vol.32 , pp. 417-421
    • Shepard, P.D.1    Holcomb, H.H.2    Gold, J.M.3
  • 164
    • 84904328761 scopus 로고    scopus 로고
    • Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula
    • Shih, P.Y., Engle, S.E., Oh, G., Deshpande, P., Puskar, N.L., Lester, H.A., Drenan, R.M., Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula. J. Neurosci. 34 (2014), 9789–9802.
    • (2014) J. Neurosci. , vol.34 , pp. 9789-9802
    • Shih, P.Y.1    Engle, S.E.2    Oh, G.3    Deshpande, P.4    Puskar, N.L.5    Lester, H.A.6    Drenan, R.M.7
  • 165
    • 0037435977 scopus 로고    scopus 로고
    • Opposite metabolic changes in the habenula and ventral tegmental area of a genetic model of helpless behavior
    • Shumake, J., Edwards, E., Gonzalez-Lima, F., Opposite metabolic changes in the habenula and ventral tegmental area of a genetic model of helpless behavior. Brain Res. 963 (2003), 274–281.
    • (2003) Brain Res. , vol.963 , pp. 274-281
    • Shumake, J.1    Edwards, E.2    Gonzalez-Lima, F.3
  • 166
    • 9644252759 scopus 로고    scopus 로고
    • Brain differences in newborn rats predisposed to helpless and depressive behavior
    • Shumake, J., Conejo-Jimenez, N., Gonzalez-Pardo, H., Gonzalez-Lima, F., Brain differences in newborn rats predisposed to helpless and depressive behavior. Brain Res. 1030 (2004), 267–276.
    • (2004) Brain Res. , vol.1030 , pp. 267-276
    • Shumake, J.1    Conejo-Jimenez, N.2    Gonzalez-Pardo, H.3    Gonzalez-Lima, F.4
  • 167
    • 84866379233 scopus 로고    scopus 로고
    • The habenula couples the dopaminergic and the serotonergic systems: application to depression in Parkinson's disease
    • Sourani, D., Eitan, R., Gordon, N., Goelman, G., The habenula couples the dopaminergic and the serotonergic systems: application to depression in Parkinson's disease. Eur. J. Neurosci. 36 (2012), 2822–2829.
    • (2012) Eur. J. Neurosci. , vol.36 , pp. 2822-2829
    • Sourani, D.1    Eitan, R.2    Gordon, N.3    Goelman, G.4
  • 168
    • 84864456653 scopus 로고    scopus 로고
    • Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance
    • Stamatakis, A.M., Stuber, G.D., Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance. Nat. Neurosci. 15 (2012), 1105–1107.
    • (2012) Nat. Neurosci. , vol.15 , pp. 1105-1107
    • Stamatakis, A.M.1    Stuber, G.D.2
  • 169
    • 84954350379 scopus 로고    scopus 로고
    • Lateral hypothalamic area glutamatergic neurons and their projections to the lateral habenula regulate feeding and reward
    • Stamatakis, A.M., Van Swieten, M., Basiri, M.L., Blair, G.A., Kantak, P., Stuber, G.D., Lateral hypothalamic area glutamatergic neurons and their projections to the lateral habenula regulate feeding and reward. J. Neurosci. 36 (2016), 302–311.
    • (2016) J. Neurosci. , vol.36 , pp. 302-311
    • Stamatakis, A.M.1    Van Swieten, M.2    Basiri, M.L.3    Blair, G.A.4    Kantak, P.5    Stuber, G.D.6
  • 170
    • 84893747641 scopus 로고    scopus 로고
    • What's better for me? Fundamental role for lateral habenula in promoting subjective decision biases
    • Stopper, C.M., Floresco, S.B., What's better for me? Fundamental role for lateral habenula in promoting subjective decision biases. Nat. Neurosci. 17 (2014), 33–35.
    • (2014) Nat. Neurosci. , vol.17 , pp. 33-35
    • Stopper, C.M.1    Floresco, S.B.2
  • 171
    • 84925867910 scopus 로고    scopus 로고
    • Dopaminergic circuitry and risk/reward decision making: implications for schizophrenia
    • Stopper, C.M., Floresco, S.B., Dopaminergic circuitry and risk/reward decision making: implications for schizophrenia. Schizophr. Bull. 41 (2015), 9–14.
    • (2015) Schizophr. Bull. , vol.41 , pp. 9-14
    • Stopper, C.M.1    Floresco, S.B.2
  • 172
    • 84907983792 scopus 로고    scopus 로고
    • Overriding phasic dopamine signals redirects action selection during risk/reward decision making
    • Stopper, C.M., Tse, M.T., Montes, D.R., Wiedman, C.R., Floresco, S.B., Overriding phasic dopamine signals redirects action selection during risk/reward decision making. Neuron 84 (2014), 177–189.
    • (2014) Neuron , vol.84 , pp. 177-189
    • Stopper, C.M.1    Tse, M.T.2    Montes, D.R.3    Wiedman, C.R.4    Floresco, S.B.5
  • 173
    • 84860311090 scopus 로고    scopus 로고
    • A new perspective on anhedonia in schizophrenia
    • Strauss, G.P., Gold, J.M., A new perspective on anhedonia in schizophrenia. Am. J. Psychiatry 169 (2012), 364–373.
    • (2012) Am. J. Psychiatry , vol.169 , pp. 364-373
    • Strauss, G.P.1    Gold, J.M.2
  • 174
    • 80054846785 scopus 로고    scopus 로고
    • Patients with schizophrenia demonstrate inconsistent preference judgments for affective and nonaffective stimuli
    • Strauss, G.P., Robinson, B.M., Waltz, J.A., Frank, M.J., Kasanova, Z., Herbener, E.S., Gold, J.M., Patients with schizophrenia demonstrate inconsistent preference judgments for affective and nonaffective stimuli. Schizophr. Bull. 37 (2011), 1295–1304.
    • (2011) Schizophr. Bull. , vol.37 , pp. 1295-1304
    • Strauss, G.P.1    Robinson, B.M.2    Waltz, J.A.3    Frank, M.J.4    Kasanova, Z.5    Herbener, E.S.6    Gold, J.M.7
  • 175
    • 84920559964 scopus 로고    scopus 로고
    • Serotonin and dopamine receptors in motivational and cognitive disturbances of schizophrenia
    • Sumiyoshi, T., Kunugi, H., Nakagome, K., Serotonin and dopamine receptors in motivational and cognitive disturbances of schizophrenia. Front. Neurosci., 8, 2014, 395.
    • (2014) Front. Neurosci. , vol.8 , pp. 395
    • Sumiyoshi, T.1    Kunugi, H.2    Nakagome, K.3
  • 176
    • 0020024556 scopus 로고
    • The dorsal diencephalic conduction system: a review of the anatomy and functions of the habenular complex
    • Sutherland, R.J., The dorsal diencephalic conduction system: a review of the anatomy and functions of the habenular complex. Neurosci. Biobehav. Rev. 6 (1982), 1–13.
    • (1982) Neurosci. Biobehav. Rev. , vol.6 , pp. 1-13
    • Sutherland, R.J.1
  • 177
    • 34248532064 scopus 로고    scopus 로고
    • 18-MC acts in the medial habenula and interpeduncular nucleus to attenuate dopamine sensitization to morphine in the nucleus accumbens
    • Taraschenko, O.D., Shulan, J.M., Maisonneuve, I.M., Glick, S.D., 18-MC acts in the medial habenula and interpeduncular nucleus to attenuate dopamine sensitization to morphine in the nucleus accumbens. Synapse 61 (2007), 547–560.
    • (2007) Synapse , vol.61 , pp. 547-560
    • Taraschenko, O.D.1    Shulan, J.M.2    Maisonneuve, I.M.3    Glick, S.D.4
  • 178
    • 41649103052 scopus 로고    scopus 로고
    • A variant associated with nicotine dependence, lung cancer and peripheral arterial disease
    • Thorgeirsson, T.E., et al. A variant associated with nicotine dependence, lung cancer and peripheral arterial disease. Nature 452 (2008), 638–642.
    • (2008) Nature , vol.452 , pp. 638-642
    • Thorgeirsson, T.E.1
  • 179
    • 0025760134 scopus 로고
    • A water-maze discrimination learning deficit in the rat following lesion of the habenula
    • Thornton, E.W., Davies, C., A water-maze discrimination learning deficit in the rat following lesion of the habenula. Physiol. Behav. 49 (1991), 819–822.
    • (1991) Physiol. Behav. , vol.49 , pp. 819-822
    • Thornton, E.W.1    Davies, C.2
  • 180
    • 84942197402 scopus 로고    scopus 로고
    • Habenula lesions reveal that multiple mechanisms underlie dopamine prediction errors
    • Tian, J., Uchida, N., Habenula lesions reveal that multiple mechanisms underlie dopamine prediction errors. Neuron 87 (2015), 1304–1316.
    • (2015) Neuron , vol.87 , pp. 1304-1316
    • Tian, J.1    Uchida, N.2
  • 181
    • 84921472636 scopus 로고    scopus 로고
    • Impaired effort allocation in patients with schizophrenia
    • Treadway, M.T., Peterman, J.S., Zald, D.H., Park, S., Impaired effort allocation in patients with schizophrenia. Schizophr. Res. 161 (2015), 382–385.
    • (2015) Schizophr. Res. , vol.161 , pp. 382-385
    • Treadway, M.T.1    Peterman, J.S.2    Zald, D.H.3    Park, S.4
  • 182
    • 0038718773 scopus 로고    scopus 로고
    • Error monitoring using external feedback: specific roles of the habenular complex, the reward system, and the cingulate motor area revealed by functional magnetic resonance imaging
    • Ullsperger, M., von Cramon, D.Y., Error monitoring using external feedback: specific roles of the habenular complex, the reward system, and the cingulate motor area revealed by functional magnetic resonance imaging. J. Neurosci. 23 (2003), 4308–4314.
    • (2003) J. Neurosci. , vol.23 , pp. 4308-4314
    • Ullsperger, M.1    von Cramon, D.Y.2
  • 185
    • 0027336093 scopus 로고
    • Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers
    • Volkow, N.D., Fowler, J.S., Wang, G.J., Hitzemann, R., Logan, J., Schlyer, D.J., Dewey, S.L., Wolf, A.P., Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers. Synapse 14 (1993), 169–177.
    • (1993) Synapse , vol.14 , pp. 169-177
    • Volkow, N.D.1    Fowler, J.S.2    Wang, G.J.3    Hitzemann, R.4    Logan, J.5    Schlyer, D.J.6    Dewey, S.L.7    Wolf, A.P.8
  • 187
    • 0032843942 scopus 로고    scopus 로고
    • Reinforcing effects of psychostimulants in humans are associated with increases in brain dopamine and occupancy of D(2) receptors
    • Volkow, N.D., Wang, G.J., Fowler, J.S., Logan, J., Gatley, S.J., Wong, C., Hitzemann, R., Pappas, N.R., Reinforcing effects of psychostimulants in humans are associated with increases in brain dopamine and occupancy of D(2) receptors. J. Pharmacol. Exp. Ther. 291 (1999), 409–415.
    • (1999) J. Pharmacol. Exp. Ther. , vol.291 , pp. 409-415
    • Volkow, N.D.1    Wang, G.J.2    Fowler, J.S.3    Logan, J.4    Gatley, S.J.5    Wong, C.6    Hitzemann, R.7    Pappas, N.R.8
  • 189
    • 0001205772 scopus 로고    scopus 로고
    • Evidence for estrogen receptor in cell nuclei and axon terminals within the lateral habenula of the rat: regulation during pregnancy
    • Wagner, C.K., Silverman, A.J., Morrell, J.I., Evidence for estrogen receptor in cell nuclei and axon terminals within the lateral habenula of the rat: regulation during pregnancy. J. Comp. Neurol. 392 (1998), 330–342.
    • (1998) J. Comp. Neurol. , vol.392 , pp. 330-342
    • Wagner, C.K.1    Silverman, A.J.2    Morrell, J.I.3
  • 190
    • 0017744244 scopus 로고
    • Physiological evidence for habenula as major link between forebrain and midbrain raphe
    • Wang, R.Y., Aghajanian, G.K., Physiological evidence for habenula as major link between forebrain and midbrain raphe. Science 197 (1977), 89–91.
    • (1977) Science , vol.197 , pp. 89-91
    • Wang, R.Y.1    Aghajanian, G.K.2
  • 192
    • 77953880653 scopus 로고    scopus 로고
    • Neurodevelopmental animal models of schizophrenia: role in novel drug discovery and development
    • Wilson, C., Terry, A.V. Jr., Neurodevelopmental animal models of schizophrenia: role in novel drug discovery and development. Clin. Schizophr. Relat. Psychoses 4 (2010), 124–137.
    • (2010) Clin. Schizophr. Relat. Psychoses , vol.4 , pp. 124-137
    • Wilson, C.1    Terry, A.V.2
  • 193
    • 78149414084 scopus 로고    scopus 로고
    • Pharmacological inhibition of the lateral habenula improves depressive-like behavior in an animal model of treatment resistant depression
    • Winter, C., Vollmayr, B., Djodari-Irani, A., Klein, J., Sartorius, A., Pharmacological inhibition of the lateral habenula improves depressive-like behavior in an animal model of treatment resistant depression. Behav. Brain Res. 216 (2011), 463–465.
    • (2011) Behav. Brain Res. , vol.216 , pp. 463-465
    • Winter, C.1    Vollmayr, B.2    Djodari-Irani, A.3    Klein, J.4    Sartorius, A.5
  • 194
    • 33751072630 scopus 로고    scopus 로고
    • Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving
    • Wong, D.F., et al. Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. Neuropsychopharmacology 31 (2006), 2716–2727.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2716-2727
    • Wong, D.F.1
  • 195
    • 84909581137 scopus 로고    scopus 로고
    • Lateral habenula deep brain stimulation for personalized treatment of drug addiction
    • Yadid, G., Gispan, I., Lax, E., Lateral habenula deep brain stimulation for personalized treatment of drug addiction. Front. Hum. Neurosci., 7, 2013, 806.
    • (2013) Front. Hum. Neurosci. , vol.7 , pp. 806
    • Yadid, G.1    Gispan, I.2    Lax, E.3
  • 196
    • 84877340712 scopus 로고    scopus 로고
    • Distinct roles of segregated transmission of the septo-habenular pathway in anxiety and fear
    • Yamaguchi, T., Danjo, T., Pastan, I., Hikida, T., Nakanishi, S., Distinct roles of segregated transmission of the septo-habenular pathway in anxiety and fear. Neuron 78 (2013), 537–544.
    • (2013) Neuron , vol.78 , pp. 537-544
    • Yamaguchi, T.1    Danjo, T.2    Pastan, I.3    Hikida, T.4    Nakanishi, S.5
  • 197
    • 38749114701 scopus 로고    scopus 로고
    • Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus
    • Yang, L.M., Hu, B., Xia, Y.H., Zhang, B.L., Zhao, H., Lateral habenula lesions improve the behavioral response in depressed rats via increasing the serotonin level in dorsal raphe nucleus. Behav. Brain Res. 188 (2008), 84–90.
    • (2008) Behav. Brain Res. , vol.188 , pp. 84-90
    • Yang, L.M.1    Hu, B.2    Xia, Y.H.3    Zhang, B.L.4    Zhao, H.5
  • 198
    • 84889594115 scopus 로고    scopus 로고
    • Substance P receptor antagonist in lateral habenula improves rat depression-like behavior
    • Yang, L.M., Yu, L., Jin, H.J., Zhao, H., Substance P receptor antagonist in lateral habenula improves rat depression-like behavior. Brain Res. Bull. 100 (2014), 22–28.
    • (2014) Brain Res. Bull. , vol.100 , pp. 22-28
    • Yang, L.M.1    Yu, L.2    Jin, H.J.3    Zhao, H.4
  • 199
    • 84858006374 scopus 로고    scopus 로고
    • Amphetamine differentially modifies the expression of monoaminergic and GABAergic synaptic boutons and processes in lateral habenula, dorsal and ventral hippocampal formation
    • Yin, H.S., Tien, T.W., Li, L., Yang, Y.H., Lai, C.C., Amphetamine differentially modifies the expression of monoaminergic and GABAergic synaptic boutons and processes in lateral habenula, dorsal and ventral hippocampal formation. Neurotoxicology 33 (2012), 235–245.
    • (2012) Neurotoxicology , vol.33 , pp. 235-245
    • Yin, H.S.1    Tien, T.W.2    Li, L.3    Yang, Y.H.4    Lai, C.C.5
  • 200
    • 64749114672 scopus 로고    scopus 로고
    • Risk/reward decision-making in schizophrenia: a preliminary examination of the influence of tobacco smoking and relationship to Wisconsin Card Sorting Task performance
    • Yip, S.W., Sacco, K.A., George, T.P., Potenza, M.N., Risk/reward decision-making in schizophrenia: a preliminary examination of the influence of tobacco smoking and relationship to Wisconsin Card Sorting Task performance. Schizophr. Res. 110 (2009), 156–164.
    • (2009) Schizophr. Res. , vol.110 , pp. 156-164
    • Yip, S.W.1    Sacco, K.A.2    George, T.P.3    Potenza, M.N.4
  • 201
    • 23044452474 scopus 로고    scopus 로고
    • Increased c-Fos expression in the medial part of the lateral habenula during cue-evoked heroin-seeking in rats
    • Zhang, F., Zhou, W., Liu, H., Zhu, H., Tang, S., Lai, M., Yang, G., Increased c-Fos expression in the medial part of the lateral habenula during cue-evoked heroin-seeking in rats. Neurosci. Lett. 386 (2005), 133–137.
    • (2005) Neurosci. Lett. , vol.386 , pp. 133-137
    • Zhang, F.1    Zhou, W.2    Liu, H.3    Zhu, H.4    Tang, S.5    Lai, M.6    Yang, G.7
  • 202
    • 84978743941 scopus 로고    scopus 로고
    • Sleep deprivation influences circadian gene expression in the lateral habenula
    • Zhang, B., Gao, Y., Li, Y., Yang, J., Zhao, H., Sleep deprivation influences circadian gene expression in the lateral habenula. Behav. Neurol., 2016, 2016, 7919534.
    • (2016) Behav. Neurol. , vol.2016 , pp. 7919534
    • Zhang, B.1    Gao, Y.2    Li, Y.3    Yang, J.4    Zhao, H.5
  • 204
    • 84876985063 scopus 로고    scopus 로고
    • Cocaine facilitates glutamatergic transmission and activates lateral habenular neurons
    • Zuo, W., Chen, L., Wang, L., Ye, J.H., Cocaine facilitates glutamatergic transmission and activates lateral habenular neurons. Neuropharmacology 70 (2013), 180–189.
    • (2013) Neuropharmacology , vol.70 , pp. 180-189
    • Zuo, W.1    Chen, L.2    Wang, L.3    Ye, J.H.4


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