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Volumn 116, Issue 3, 2016, Pages 1161-1174

Functional evidence for a direct excitatory projection from the lateral habenula to the ventral tegmental area in the rat

Author keywords

Brain slice; Dopamine; Lateral habenula; Rostromedial tegmental nucleus; Tail of the ventral tegmental area; Tyrosine hydroxylase

Indexed keywords

GLUTAMATE RECEPTOR AGONIST; DOPAMINE; GLUTAMATE RECEPTOR; PROTEIN C FOS; TYROSINE 3 MONOOXYGENASE;

EID: 84986216627     PISSN: 00223077     EISSN: 15221598     Source Type: Journal    
DOI: 10.1152/jn.00305.2016     Document Type: Article
Times cited : (36)

References (66)
  • 1
    • 0024347713 scopus 로고
    • Intracellular studies in the facial nucleus illustrating a simple new methd for obtaining viable motoneurons in adult rat brain slices
    • Aghajanian GK, Rasmussen K. Intracellular studies in the facial nucleus illustrating a simple new methd for obtaining viable motoneurons in adult rat brain slices. Synapse 3: 331-338, 1989.
    • (1989) Synapse , vol.3 , pp. 331-338
    • Aghajanian, G.K.1    Rasmussen, K.2
  • 2
    • 79951808106 scopus 로고    scopus 로고
    • The inhibitory influence of the lateral habenula on midbrain dopamine cells: Ultrastructural evidence for indirect mediation via the rostromedial mesopontine tegmental nucleus
    • Balcita-Pedicino JJ, Omelchenko N, Bell R, Sesack SR. The inhibitory influence of the lateral habenula on midbrain dopamine cells: Ultrastructural evidence for indirect mediation via the rostromedial mesopontine tegmental nucleus. J Comp Neurol 519: 1143-1164, 2011.
    • (2011) J Comp Neurol , vol.519 , pp. 1143-1164
    • Balcita-Pedicino, J.J.1    Omelchenko, N.2    Bell, R.3    Sesack, S.R.4
  • 3
    • 0024590774 scopus 로고
    • Cells of the rat lateral habenula respond to highthreshold somatosensory inputs
    • Benabid AL, Jeaugey L. Cells of the rat lateral habenula respond to highthreshold somatosensory inputs. Neurosci Lett 96: 289-294, 1989.
    • (1989) Neurosci Lett , vol.96 , pp. 289-294
    • Benabid, A.L.1    Jeaugey, L.2
  • 4
    • 0027954505 scopus 로고
    • Differential expression of tyrosine hydroxylase and membrane dopamine transporter genes in subpopulations of dopaminergic neurons of the rat mesencephalon
    • Blanchard V, Raisman-Vozari R, Vyas S, Michel PP, Javoy-Agid F, Uhl G, Agid Y. Differential expression of tyrosine hydroxylase and membrane dopamine transporter genes in subpopulations of dopaminergic neurons of the rat mesencephalon. Brain Res Mol Brain Res 22: 29-38, 1994.
    • (1994) Brain Res Mol Brain Res , vol.22 , pp. 29-38
    • Blanchard, V.1    Raisman-Vozari, R.2    Vyas, S.3    Michel, P.P.4    Javoy-Agid, F.5    Uhl, G.6    Agid, Y.7
  • 5
    • 77952876978 scopus 로고    scopus 로고
    • Glutamatergic axons from the lateral habenula mainly terminate on GABAergic neurons of the ventral midbrain
    • Brinschwitz K, Dittgen A, Madai VI, Lommel R, Geisler S, Veh RW. Glutamatergic axons from the lateral habenula mainly terminate on GABAergic neurons of the ventral midbrain. Neuroscience 168: 463-476, 2010.
    • (2010) Neuroscience , vol.168 , pp. 463-476
    • Brinschwitz, K.1    Dittgen, A.2    Madai, V.I.3    Lommel, R.4    Geisler, S.5    Veh, R.W.6
  • 7
    • 51249084370 scopus 로고    scopus 로고
    • Enhanced methamphetamine self-administration in a neurodevelopmental rat model of schizophrenia
    • Brady AM, McCallum SE, Glick SD, O’Donnell P. Enhanced methamphetamine self-administration in a neurodevelopmental rat model of schizophrenia. Psychopharmacology 200: 205-215, 2008.
    • (2008) Psychopharmacology , vol.200 , pp. 205-215
    • Brady, A.M.1    McCallum, S.E.2    Glick, S.D.3    O’Donnell, P.4
  • 8
    • 0030435365 scopus 로고    scopus 로고
    • Global sex differences in stress-induced activation of cerebral metabolism revealed by 2-deoxyglucose autoradiography
    • Brown LL, Siegel H, Etgen AM. Global sex differences in stress-induced activation of cerebral metabolism revealed by 2-deoxyglucose autoradiography. Horm Behav 30: 611-617, 1996.
    • (1996) Horm Behav , vol.30 , pp. 611-617
    • Brown, L.L.1    Siegel, H.2    Etgen, A.M.3
  • 9
    • 84876074520 scopus 로고    scopus 로고
    • Lesions of the fasciculus retroflexus alter footshockinduced cFos expression in the mesopontine rostromedial tegmental area of rats
    • Brown PL, Shepard PD. Lesions of the fasciculus retroflexus alter footshockinduced cFos expression in the mesopontine rostromedial tegmental area of rats. PLos One 8: e60678, 2013.
    • (2013) PLos One , vol.8
    • Brown, P.L.1    Shepard, P.D.2
  • 10
    • 35649002144 scopus 로고    scopus 로고
    • Computational model predicts a role for ERG current in repolarizing plateau potentials in dopamine neurons: Implications for modulation of neuronal activity
    • Canavier CC, Oprisan SA, Callaway JC, Ji H, Shepard PD. Computational model predicts a role for ERG current in repolarizing plateau potentials in dopamine neurons: implications for modulation of neuronal activity. J Neurophysiol 98: 3006-3022, 2007.
    • (2007) J Neurophysiol , vol.98 , pp. 3006-3022
    • Canavier, C.C.1    Oprisan, S.A.2    Callaway, J.C.3    Ji, H.4    Shepard, P.D.5
  • 11
    • 0033559388 scopus 로고    scopus 로고
    • Passive electrotonic properties of rat hippocampal CA3 interneurones
    • Chitwood RA, Hubbard A, Jaffe DB. Passive electrotonic properties of rat hippocampal CA3 interneurones. J Physiol 515: 743-756, 1999.
    • (1999) J Physiol , vol.515 , pp. 743-756
    • Chitwood, R.A.1    Hubbard, A.2    Jaffe, D.B.3
  • 12
    • 0022644104 scopus 로고
    • Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat
    • Christoph GR, Leonzio RJ, Wilcox KS. Stimulation of the lateral habenula inhibits dopamine-containing neurons in the substantia nigra and ventral tegmental area of the rat. J Neurosci 6: 613-619, 1986.
    • (1986) J Neurosci , vol.6 , pp. 613-619
    • Christoph, G.R.1    Leonzio, R.J.2    Wilcox, K.S.3
  • 13
    • 84856431209 scopus 로고    scopus 로고
    • Neuron-type-specific signals for reward and punishment in the ventral tegmental area
    • Cohen JY, Haesler S, Vong L, Lowell BB, Uchida N. Neuron-type-specific signals for reward and punishment in the ventral tegmental area. Nature 482: 85-88, 2012.
    • (2012) Nature , vol.482 , pp. 85-88
    • Cohen, J.Y.1    Haesler, S.2    Vong, L.3    Lowell, B.B.4    Uchida, N.5
  • 14
    • 84891501866 scopus 로고    scopus 로고
    • 8th ed.). Washington, DC: National Academic Press
    • Committee for the Update of the Guide for the Care and Use of Laboratory Animals. Guide for the Care and Use of Laboratory Animals (8th ed.). Washington, DC: National Academic Press, 2011.
    • (2011) Guide for the Care and Use of Laboratory Animals
  • 15
    • 0025672802 scopus 로고
    • The determinants of stress-induced activation of the prefrontal cortical dopamine system
    • Deutch AY, Roth RH. The determinants of stress-induced activation of the prefrontal cortical dopamine system. Prog Brain Res 85: 363-402, 1990.
    • (1990) Prog Brain Res , vol.85 , pp. 363-402
    • Deutch, A.Y.1    Roth, R.H.2
  • 16
    • 0035025304 scopus 로고    scopus 로고
    • Reliability of monosynaptic sensory transmission in brain stem neurons in vitro
    • Doyle MW, Andresen MC. Reliability of monosynaptic sensory transmission in brain stem neurons in vitro. J Neurophysiol 85: 2213-2223, 2001.
    • (2001) J Neurophysiol , vol.85 , pp. 2213-2223
    • Doyle, M.W.1    Andresen, M.C.2
  • 17
    • 33644832076 scopus 로고    scopus 로고
    • Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location
    • Ford CP, Mark GP, Williams JT. Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location. J Neurosci 26: 2788-2797, 2006.
    • (2006) J Neurosci , vol.26 , pp. 2788-2797
    • Ford, C.P.1    Mark, G.P.2    Williams, J.T.3
  • 18
    • 0025116093 scopus 로고
    • Intensity-dependent nociceptive responses from presumed dopaminergic neurons of the substantia nigra, pars compacta in the rat and their modification by lateral habenula inputs
    • Gao DM, Jeaugey L, Pollak P, Benabid AL. Intensity-dependent nociceptive responses from presumed dopaminergic neurons of the substantia nigra, pars compacta in the rat and their modification by lateral habenula inputs. Brain Res 529: 315-319, 1990.
    • (1990) Brain Res , vol.529 , pp. 315-319
    • Gao, D.M.1    Jeaugey, L.2    Pollak, P.3    Benabid, A.L.4
  • 19
    • 0020686624 scopus 로고
    • An electrophysiological study of convrgence of entopeduncular and lateral preoptic inputs on lateral habenular neurons projecting to the midbrain
    • Garland JC, Mogenson GJ. An electrophysiological study of convrgence of entopeduncular and lateral preoptic inputs on lateral habenular neurons projecting to the midbrain. Brain Res 263: 33-41, 1983.
    • (1983) Brain Res , vol.263 , pp. 33-41
    • Garland, J.C.1    Mogenson, G.J.2
  • 20
    • 34250640627 scopus 로고    scopus 로고
    • Glutamatergic afferents of the ventral tegmental area in the rat
    • Geisler S, Derst C, Veh RW, Zahm DS. Glutamatergic afferents of the ventral tegmental area in the rat. J Neurosci 27: 5730-5743, 2007.
    • (2007) J Neurosci , vol.27 , pp. 5730-5743
    • Geisler, S.1    Derst, C.2    Veh, R.W.3    Zahm, D.S.4
  • 21
    • 84856710306 scopus 로고    scopus 로고
    • Differential projections from the lateral habenula to the rostromedial tegmental nucleus and ventral tegmental area in the rat
    • Goncalves L, Sego C, Metzger M. Differential projections from the lateral habenula to the rostromedial tegmental nucleus and ventral tegmental area in the rat. J Comp Neurol 520: 1278-1300, 2012.
    • (2012) J Comp Neurol , vol.520 , pp. 1278-1300
    • Goncalves, L.1    Sego, C.2    Metzger, M.3
  • 22
    • 0032914820 scopus 로고    scopus 로고
    • An electrophysiological characterization of ventral tegmental area dopaminergic neurons during differential pavlovian fear conditioning in the awake rabbit
    • Guarraci FA, Kapp BS. An electrophysiological characterization of ventral tegmental area dopaminergic neurons during differential pavlovian fear conditioning in the awake rabbit. Behav Brain Res 99: 169-179, 1999.
    • (1999) Behav Brain Res , vol.99 , pp. 169-179
    • Guarraci, F.A.1    Kapp, B.S.2
  • 23
    • 0018647716 scopus 로고
    • Efferent connections of the habenular nuclei in the rat
    • Herkenham M, Nauta WJ. Efferent connections of the habenular nuclei in the rat. J Comp Neurol 187: 19-47, 1979.
    • (1979) J Comp Neurol , vol.187 , pp. 19-47
    • Herkenham, M.1    Nauta, W.J.2
  • 24
    • 80051565543 scopus 로고    scopus 로고
    • Negative reward signals from lateral habenula to dopamine neurons are mediated by rostromedial tegmental nucleus in primates
    • Hong S, Jhou T, Smith M, Saleem K, Hikosaka O. Negative reward signals from lateral habenula to dopamine neurons are mediated by rostromedial tegmental nucleus in primates. J Neurosci 31: 11457-11471, 2011.
    • (2011) J Neurosci , vol.31 , pp. 11457-11471
    • Hong, S.1    Jhou, T.2    Smith, M.3    Saleem, K.4    Hikosaka, O.5
  • 25
    • 61549112212 scopus 로고    scopus 로고
    • The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses
    • Jhou TC, Fields HL, Baxter MG, Saper CB, Holland PC. The rostromedial tegmental nucleus (RMTg), a GABAergic afferent to midbrain dopamine neurons, encodes aversive stimuli and inhibits motor responses. Neuron 61: 786-800, 2009a.
    • (2009) Neuron , vol.61 , pp. 786-800
    • Jhou, T.C.1    Fields, H.L.2    Baxter, M.G.3    Saper, C.B.4    Holland, P.C.5
  • 26
    • 61549142101 scopus 로고    scopus 로고
    • The mesopontine rostromedial tegmental nucleus: A structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta
    • Jhou TC, Geisler S, Marinelli M, Degarmo BA, Zahm DS. The mesopontine rostromedial tegmental nucleus: a structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta. J Comp Neurol 513: 566-596, 2009b.
    • (2009) J Comp Neurol , vol.513 , pp. 566-596
    • Jhou, T.C.1    Geisler, S.2    Marinelli, M.3    Degarmo, B.A.4    Zahm, D.S.5
  • 28
    • 34347324115 scopus 로고    scopus 로고
    • Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABAA receptor-mediated mechanism
    • Ji H, Shepard PD. Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABAA receptor-mediated mechanism. J Neurosci 27: 6923-6930, 2007.
    • (2007) J Neurosci , vol.27 , pp. 6923-6930
    • Ji, H.1    Shepard, P.D.2
  • 30
    • 40249097514 scopus 로고    scopus 로고
    • Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system
    • Lammel S, Hetzel A, Hackel O, Jones I, Liss B, Roeper J. Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system. Neuron 57: 760-773, 2008.
    • (2008) Neuron , vol.57 , pp. 760-773
    • Lammel, S.1    Hetzel, A.2    Hackel, O.3    Jones, I.4    Liss, B.5    Roeper, J.6
  • 31
    • 79958055503 scopus 로고    scopus 로고
    • Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli
    • Lammel S, Ion DI, Roeper J, Malenka RC. Projection-specific modulation of dopamine neuron synapses by aversive and rewarding stimuli. Neuron 70: 855-862, 2011.
    • (2011) Neuron , vol.70 , pp. 855-862
    • Lammel, S.1    Ion, D.I.2    Roeper, J.3    Malenka, R.C.4
  • 33
    • 84858337203 scopus 로고    scopus 로고
    • Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse
    • Lecca S, Melis M, Luchicchi A, Muntoni AL, Pistis M. Inhibitory inputs from rostromedial tegmental neurons regulate spontaneous activity of midbrain dopamine cells and their responses to drugs of abuse. Neuropsychopharmacology 37: 1164-1176, 2012.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 1164-1176
    • Lecca, S.1    Melis, M.2    Luchicchi, A.3    Muntoni, A.L.4    Pistis, M.5
  • 34
    • 7444235358 scopus 로고    scopus 로고
    • Glutamate and acetylcholine corelease at developing synapses
    • Li WC, Soffe SR, Roberts A. Glutamate and acetylcholine corelease at developing synapses. Proc Natl Acad Sci USA 101: 15488-15493, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 15488-15493
    • Li, W.C.1    Soffe, S.R.2    Roberts, A.3
  • 35
    • 84883185257 scopus 로고    scopus 로고
    • Heterogeneous composition of dopamine neurons of the rat A10 region: Molecular evidence for diverse signaling properties
    • Li X, Qi J, Yamaguchi T, Wang HL, Morales M. Heterogeneous composition of dopamine neurons of the rat A10 region: molecular evidence for diverse signaling properties. Brain Struct Funct 218: 1159-1176, 2013.
    • (2013) Brain Struct Funct , vol.218 , pp. 1159-1176
    • Li, X.1    Qi, J.2    Yamaguchi, T.3    Wang, H.L.4    Morales, M.5
  • 37
    • 33845305449 scopus 로고    scopus 로고
    • The ventral tegmental area revisited: Is there an electrophysiological marker for dopaminergic neurons?
    • Margolis EB, Lock H, Hjelmstad GO, Fields HL. The ventral tegmental area revisited: is there an electrophysiological marker for dopaminergic neurons? J Physiol 577: 907-924, 2006.
    • (2006) J Physiol , vol.577 , pp. 907-924
    • Margolis, E.B.1    Lock, H.2    Hjelmstad, G.O.3    Fields, H.L.4
  • 38
    • 0026694984 scopus 로고
    • Action of habenular efferents on ventral tegmental area neurons studied in vitro
    • Matsuda Y, Fujimura K. Action of habenular efferents on ventral tegmental area neurons studied in vitro. Brain Res Bull 28: 743-749, 1992.
    • (1992) Brain Res Bull , vol.28 , pp. 743-749
    • Matsuda, Y.1    Fujimura, K.2
  • 39
    • 82555174612 scopus 로고    scopus 로고
    • Opioid-sensitive GABA inputs from rostromedial tegmental nucleus synapse onto midbrain dopamine neurons
    • Matsui A, Williams JT. Opioid-sensitive GABA inputs from rostromedial tegmental nucleus synapse onto midbrain dopamine neurons. J Neurosci 31: 17729-17735, 2011.
    • (2011) J Neurosci , vol.31 , pp. 17729-17735
    • Matsui, A.1    Williams, J.T.2
  • 40
    • 58149127270 scopus 로고    scopus 로고
    • Representation of negative motivational value in the primate lateral habenula
    • Matsumoto M, Hikosaka O. Representation of negative motivational value in the primate lateral habenula. Nat Neurosci 12: 77-84, 2009.
    • (2009) Nat Neurosci , vol.12 , pp. 77-84
    • Matsumoto, M.1    Hikosaka, O.2
  • 42
    • 0030026069 scopus 로고    scopus 로고
    • Preferential activation of midbrain dopamine neurons by appetitive rather than aversive stimuli
    • Mirenowicz J, Schultz W. Preferential activation of midbrain dopamine neurons by appetitive rather than aversive stimuli. Nature 379: 449-451, 1996.
    • (1996) Nature , vol.379 , pp. 449-451
    • Mirenowicz, J.1    Schultz, W.2
  • 43
    • 84893262308 scopus 로고    scopus 로고
    • Increased metabolic activity in the septum and habenula during stress is linked to subsequent expression of learned helplessness behavior
    • Mirrione MM, Schulz D, Lapidus KA, Zhang S, Goodman W, Henn FA. Increased metabolic activity in the septum and habenula during stress is linked to subsequent expression of learned helplessness behavior. Front Hum Neurosci 8: 29, 2014.
    • (2014) Front Hum Neurosci , vol.8 , pp. 29
    • Mirrione, M.M.1    Schulz, D.2    Lapidus, K.A.3    Zhang, S.4    Goodman, W.5    Henn, F.A.6
  • 44
    • 0029981543 scopus 로고    scopus 로고
    • A framework for mesencephalic dopamine systems based on predictive Hebbian learning
    • Montague PR, Dayan P, Sejnowski TJ. A framework for mesencephalic dopamine systems based on predictive Hebbian learning. J Neurosci 16: 1936-1947, 1996.
    • (1996) J Neurosci , vol.16 , pp. 1936-1947
    • Montague, P.R.1    Dayan, P.2    Sejnowski, T.J.3
  • 45
    • 78049294641 scopus 로고    scopus 로고
    • Adolescent maturation of cortical dopamine
    • O’Donnell P. Adolescent maturation of cortical dopamine. Neurotoxicity Res 18: 306-312, 2010.
    • (2010) Neurotoxicity Res , vol.18 , pp. 306-312
    • O’Donnell, P.1
  • 46
    • 70350437997 scopus 로고    scopus 로고
    • Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area
    • Omelchenko N, Bell R, Sesack SR. Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area. Eur J Neurosci 30: 1239-1250, 2009.
    • (2009) Eur J Neurosci , vol.30 , pp. 1239-1250
    • Omelchenko, N.1    Bell, R.2    Sesack, S.R.3
  • 47
    • 0023440668 scopus 로고
    • Monosynaptic inhibitory postsynaptic potentials from lateral habenula recorded in dorsal raphe neurons
    • Park MR. Monosynaptic inhibitory postsynaptic potentials from lateral habenula recorded in dorsal raphe neurons. Brain Res Bull 19: 581-586, 1987.
    • (1987) Brain Res Bull , vol.19 , pp. 581-586
    • Park, M.R.1
  • 48
    • 36448968271 scopus 로고    scopus 로고
    • Dopamine neurons encode the better option in rats deciding between differently delayed or sized rewards
    • Roesch MR, Calu DJ, Schoenbaum G. Dopamine neurons encode the better option in rats deciding between differently delayed or sized rewards. Nat Neurosci 10: 1615-1624, 2007.
    • (2007) Nat Neurosci , vol.10 , pp. 1615-1624
    • Roesch, M.R.1    Calu, D.J.2    Schoenbaum, G.3
  • 49
    • 84859339780 scopus 로고    scopus 로고
    • Surprise! Neural correlates of Pearce-Hall and Rescorla-Wagner coexist within the brain
    • Roesch MR, Esber GR, Li J, Daw ND, Schoenbaum G. Surprise! Neural correlates of Pearce-Hall and Rescorla-Wagner coexist within the brain. Eur J Neurosci 35: 1190-1200, 2012.
    • (2012) Eur J Neurosci , vol.35 , pp. 1190-1200
    • Roesch, M.R.1    Esber, G.R.2    Li, J.3    Daw, N.D.4    Schoenbaum, G.5
  • 50
    • 0031867046 scopus 로고    scopus 로고
    • Predictive reward signal of dopamine neurons
    • Schultz W. Predictive reward signal of dopamine neurons. J Neurophysiol 80: 1-27, 1998.
    • (1998) J Neurophysiol , vol.80 , pp. 1-27
    • Schultz, W.1
  • 51
    • 65949094567 scopus 로고    scopus 로고
    • Two GABAergic intraglomerular circuits differentially regulate tonic and phasic presynaptic inhibition of olfactory nerve terminals
    • Shao Z, Puche AC, Kiyokage E, Szabo G, Shipley MT. Two GABAergic intraglomerular circuits differentially regulate tonic and phasic presynaptic inhibition of olfactory nerve terminals. J Neurophysiol 101: 1988-2001, 2009.
    • (2009) J Neurophysiol , vol.101 , pp. 1988-2001
    • Shao, Z.1    Puche, A.C.2    Kiyokage, E.3    Szabo, G.4    Shipley, M.T.5
  • 52
    • 84930400900 scopus 로고    scopus 로고
    • Your chi-square test is statistically significant: Now what?
    • Sharpe D. Your chi-square test is statistically significant: now what? Pract Assess Res Eval 20: 2-10, 2015.
    • (2015) Pract Assess Res Eval , vol.20 , pp. 2-10
    • Sharpe, D.1
  • 53
    • 0025820663 scopus 로고
    • Repetitive firing properties of putative dopaminecontaining neurons in vitro: Regulation by an apamin-sensitive Ca2_-activated K_ conductance
    • Shepard PD, Bunney BS. Repetitive firing properties of putative dopaminecontaining neurons in vitro: regulation by an apamin-sensitive Ca2_-activated K_ conductance. Exp Brain Res 86: 141-150, 1991.
    • (1991) Exp Brain Res , vol.86 , pp. 141-150
    • Shepard, P.D.1    Bunney, B.S.2
  • 55
    • 84864456653 scopus 로고    scopus 로고
    • Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance
    • Stamatakis AM, Stuber GD. Activation of lateral habenula inputs to the ventral midbrain promotes behavioral avoidance. Nat Neurosci 15: 1105-1107, 2012.
    • (2012) Nat Neurosci , vol.15 , pp. 1105-1107
    • Stamatakis, A.M.1    Stuber, G.D.2
  • 56
    • 84907983792 scopus 로고    scopus 로고
    • Overriding phasic dopamine signals redirects action selection during risk/reward decision making
    • Stopper CM, Tse MT, Montes DR, Wiedman CR, Floresco SB. Overriding phasic dopamine signals redirects action selection during risk/reward decision making. Neuron 84: 177-189, 2014.
    • (2014) Neuron , vol.84 , pp. 177-189
    • Stopper, C.M.1    Tse, M.T.2    Montes, D.R.3    Wiedman, C.R.4    Floresco, S.B.5
  • 57
    • 0020024556 scopus 로고
    • The dorsal diencephalic conduction system: A review of the anatomy and functions of the habenular complex
    • Sutherland RJ. The dorsal diencephalic conduction system: a review of the anatomy and functions of the habenular complex. Neurosci Biobehav Rev 6: 1-13, 1982.
    • (1982) Neurosci Biobehav Rev , vol.6 , pp. 1-13
    • Sutherland, R.J.1
  • 59
    • 0017167056 scopus 로고
    • Selective activation of mesocortical DA system by stress
    • Thierry AM, Tassin JP, Blanc G, Glowinski J. Selective activation of mesocortical DA system by stress. Nature 263: 242-244, 1976.
    • (1976) Nature , vol.263 , pp. 242-244
    • Thierry, A.M.1    Tassin, J.P.2    Blanc, G.3    Glowinski, J.4
  • 60
    • 84924923541 scopus 로고    scopus 로고
    • Acute brain slice methods for adult and aging animals: Application of targeted patch clamp analysis and optogenetics
    • Ting JT, Daigle TL, Chen Q, Feng G. Acute brain slice methods for adult and aging animals: application of targeted patch clamp analysis and optogenetics. Methods Mol Biol 1183: 221-242, 2014.
    • (2014) Methods Mol Biol , vol.1183 , pp. 221-242
    • Ting, J.T.1    Daigle, T.L.2    Chen, Q.3    Feng, G.4
  • 61
    • 1642404961 scopus 로고    scopus 로고
    • Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli
    • Ungless MA, Magill PJ, Bolam JP. Uniform inhibition of dopamine neurons in the ventral tegmental area by aversive stimuli. Science 303: 2040-2042, 2004.
    • (2004) Science , vol.303 , pp. 2040-2042
    • Ungless, M.A.1    Magill, P.J.2    Bolam, J.P.3
  • 62
    • 84858626050 scopus 로고    scopus 로고
    • Activation of VTA GABA neurons disrupts reward consumption
    • van Zessen R, Phillips JL, Budygin EA, Stuber GD. Activation of VTA GABA neurons disrupts reward consumption. Neuron 73: 1184-1194, 2012.
    • (2012) Neuron , vol.73 , pp. 1184-1194
    • van Zessen, R.1    Phillips, J.L.2    Budygin, E.A.3    Stuber, G.D.4
  • 63
    • 79951909857 scopus 로고    scopus 로고
    • Convergent processing of both positive and negative motivational signals by the VTA dopamine neuronal populations
    • Wang DV, Tsien JZ. Convergent processing of both positive and negative motivational signals by the VTA dopamine neuronal populations. PLos One 6: e17047, 2011.
    • (2011) PLos One , vol.6
    • Wang, D.V.1    Tsien, J.Z.2
  • 64
    • 0035873231 scopus 로고    scopus 로고
    • Differential expression of the small-conductance, calcium-activated potassium channel SK3 is critical for pacemaker control in dopaminergic midbrain neurons
    • Wolfart J, Neuhoff H, Franz O, Roeper J. Differential expression of the small-conductance, calcium-activated potassium channel SK3 is critical for pacemaker control in dopaminergic midbrain neurons. J Neurosci 21: 3443-3456, 2001.
    • (2001) J Neurosci , vol.21 , pp. 3443-3456
    • Wolfart, J.1    Neuhoff, H.2    Franz, O.3    Roeper, J.4
  • 65
    • 84925203366 scopus 로고    scopus 로고
    • Glutamatergic and dopaminergic neurons in the mouse ventral tegmental area
    • Yamaguchi T, Qi J, Wang HL, Zhang S, Morales M. Glutamatergic and dopaminergic neurons in the mouse ventral tegmental area. Eur J Neurosci 41: 760-772, 2015.
    • (2015) Eur J Neurosci , vol.41 , pp. 760-772
    • Yamaguchi, T.1    Qi, J.2    Wang, H.L.3    Zhang, S.4    Morales, M.5
  • 66
    • 84893770996 scopus 로고    scopus 로고
    • Protracted maturation of forebrain afferent connections of the ventral tegmental area in the rat
    • Yetnikoff L, Reichard RA, Schwartz ZM, Parsely KP, Zahm DS. Protracted maturation of forebrain afferent connections of the ventral tegmental area in the rat. J Comp Neurol 522: 1031-1047, 2014.
    • (2014) J Comp Neurol , vol.522 , pp. 1031-1047
    • Yetnikoff, L.1    Reichard, R.A.2    Schwartz, Z.M.3    Parsely, K.P.4    Zahm, D.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.